# ma:nyo Bifida Biome Aqua Barrier Cream for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/nl/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [ma:nyo](https://lovi.care/skincare/nl/brands/ma-nyo)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/nl/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Excellent for your oily skin, this cream utilizes niacinamide and betaine salicylate to help regulate oil production and gently exfoliate pores, addressing your concerns with acne and breakouts.
- The inclusion of Bifida Lysate Ferment and Centella Asiatica Leaf Water provides significant barrier support and hydration, enhancing skin resilience.
- This formula is safe for your skin, featuring soothing ingredients like Centella Asiatica Leaf Water and Licorice Root Extract with no risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/nl/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/nl/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/nl/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/nl/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/nl/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/nl/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Bifida Lysate Ferment, Centella Asiatica Leaf Water, Niacinamide, Sodium Hyaluronate, Ceramide Np

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

This cream is highly praised for its lightweight, gel-like texture that effectively soothes sensitive skin and repairs the moisture barrier without causing breakouts. It is particularly beneficial for combination and oily skin types, providing deep hydration and a plump appearance. However, individuals with very dry skin or those in dry climates may find it insufficient on its own, needing to layer it with a richer product.

- Liked: Lightweight, non-greasy (mostly mentioned)
- Liked: Hydrating and plumping (often mentioned)
- Liked: Soothing and calming (often mentioned)
- Liked: Strengthens barrier (sometimes noted)
- Disliked: Not enough occlusion (sometimes noted)
- Disliked: Minor irritation (rarely noted)
- Disliked: Unstable packaging (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes ma:nyo Aqua Barrier Cream a great fit for oily acne-prone skin?

This cream is a great fit because niacinamide and betaine salicylate help control oil and clear pores, while Centella Asiatica Leaf Water and licorice root soothe the skin without causing irritation. It also helps strengthen your skin barrier and provides lightweight hydration.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Which ingredients make this cream a good fit for oily acne-prone skin?

Niacinamide and betaine salicylate make this cream a great fit for your oily acne-prone skin because they help regulate oil production and gently exfoliate pores. Additionally, Centella asiatica leaf water and licorice root extract provide soothing benefits with an excellent safety profile that is unlikely to cause irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Bifida Ferment Lysate do for oily acne-prone skin?

Bifida Ferment Lysate helps calm oily acne-prone skin by strengthening your skin barrier and lowering irritation. It is unlikely to clog pores and may help keep your skin feeling smooth and balanced.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/), [Experimental Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/19624730/)

### What does Centella Asiatica Leaf Water do for oily acne-prone skin?

Centella Asiatica Leaf Water helps calm red, angry blemishes and supports barrier repair without feeling heavy on oily skin. It helps reduce moisture loss and may reduce acne breakouts.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Where does this cream go in a skincare routine for oily acne-prone skin?

This cream goes as the moisturizer step in your morning and evening skincare routines. It helps hydrate your skin while keeping oil production balanced and calming breakouts.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this cream with retinol, and in what order?

Yes, you can use this cream with retinol by applying the moisturizer before or after your retinol treatment to help soothe your skin and keep it hydrated. Using a barrier-supporting moisturizer alongside retinol helps reduce common irritation and dryness while improving your skin's tolerance.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37276158/)

### How often should I use this cream?

You can use this cream daily as part of your morning and evening routine to keep your skin hydrated and balanced. Daily application helps improve skin moisture and supports the skin barrier while managing oil and breakouts.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?

This cream is unlikely to clog pores or cause breakouts on oily acne-prone skin, as it features niacinamide and betaine salicylate to help balance oil and gently clear pores. Its soothing ingredients also keep the risk of irritation very low.

### Can I use this cream around the eyes or on my body?

This cream is safe to use around the eyes and on the body because it features gentle, soothing ingredients like Centella asiatica leaf water and licorice root extract with no risk of irritation. Its light moisturizing treatment formula provides safe hydration and barrier support for delicate areas.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/nl/p/belif/the-true-cream-aqua-bomb/for/oily-acne-prone-skin) — High fit — €35.96 at Amazon
- [ANUA Heartleaf 70% Soothing Cream](https://lovi.care/skincare/nl/p/anua/heartleaf-70-soothing-cream/for/oily-acne-prone-skin) — High fit — €25.29 at Amazon
- [Anua Heartleaf 78% Soothing Cream](https://lovi.care/skincare/nl/p/anua/heartleaf-78-soothing-cream/for/oily-acne-prone-skin) — High fit — €25.29 at Amazon

## Pairs well with

- Cleanser: [Paula's Choice CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/nl/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — €29.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-acne-prone-skin) — Superior fit — €33.70 at Amazon

## Where to buy

- Amazon.nl: €21.54 (https://www.amazon.nl/dp/B09DKGF8DV?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Bifida Lysate Ferment, Centella Asiatica Leaf Water, Water, Propanediol, Glycerin, Butylene Glycol, Niacinamide, Isononyl Isononanoate, 1,2-Hexanediol, Hydrogenated Polydecene, Pentylene Glycol, Dimethicone, Bifida Ferment Filtrate, Lactobacillus Pumpkin Fruit Ferment Filtrate, Lactobacillus Lysate Ferment, Lactococcus Lysate Ferment, Saccharomyces Ferment Filtrate, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Lactobacillus Ferment, Witch Hazel Water, Vincetoxicum Atratum Extract, Anastatica Hierochuntica Extract, Chrysanthemum Zawadskii Extract, Artemisia Capillaris Extract, Cyperus Rotundus Root Extract, Leonurus Sibiricus Stem Extract Flower Leaf, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Oenothera Biennis Extract, Pinus Palustris Leaf Extract, Pueraria Lobata Root Extract, Ulmus Davidiana Root Extract, Panthenol, Borago Officinalis Extract, Centaurea Cyanus Flower Extract, Chamomilla Recutita Leaf Extract Flower Matricaria Leaf Extract Flower, Hyacinthus Orientalis Extract, Lavender Flower Water, Salvia Sclarea Extract, Ceramide Np, Hydrogenated Olive Oil, Squalane, Sodium Hyaluronate Crosspolymer, Fructooligosaccharides, Fructose, Tromethamine, Asiaticoside, Asiatic Acid, Madecassic Acid, Chlorella Vulgaris Extract, Pentaerythrityl Tetraethylhexaate, Paeonia Albiflora Flower Extract, Gossypium Herbaceum Seed Extract, Ammonium Acryloyldimethyltaurate Vp Copolymer, Polydecene, Glucose, Polyglyceryl-3 Methylglucose Distearate, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Theobroma Cacao Seed Extract, Hydrolyzed Glycosaminoglycans, Agar, Guar Gum, Xanthan Gum, Ethylhexylglycerin, Glyceryl Acrylate Acrylic Acid Copolymer, Dimethyl Sulfone, Betaine Salicylate, Hydrogenated Lecithin, Benzyl Glycol, Dextrin, Sodium Phytate, Adenosine, Tocopherol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/oily-acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/oily-acne-prone-skin (this page)
- Spain: https://lovi.care/skincare/es/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/ma-nyo/bifida-biome-aqua-barrier-cream/for/oily-acne-prone-skin