# LANEIGE Radian-C Vitamin Spot Serum 15.2% for acne-prone skin

**Lovi Fit: Superior fit for acne-prone skin.**
Combination Skin Fit: Superior · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/nl/p/laneige/radian-c-vitamin-spot-serum-15-2/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [LANEIGE](https://lovi.care/skincare/nl/brands/laneige)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for acne-prone skin.

## Why this fit

- Excellent suitability for your combination skin and acne concerns is provided by the high concentrations of Ascorbic Acid and 3-O-Ethyl Ascorbic Acid, which effectively brighten and even your skin tone while offering antioxidant and anti-inflammatory benefits. Niacinamide and Tranexamic Acid further support these actions by regulating melanogenesis and reducing inflammation, contributing to clearer, more radiant skin.
- The inclusion of Tocopherol and Centella Asiatica Stem Extract Flower Leaf ensures a soothing experience, minimizing any potential irritation for your combination skin.
- This formula is safe for your skin, with no harsh ingredients and a focus on soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/laneige/radian-c-vitamin-spot-serum-15-2/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/nl/p/laneige/radian-c-vitamin-spot-serum-15-2/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/nl/p/laneige/radian-c-vitamin-spot-serum-15-2/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/nl/p/laneige/radian-c-vitamin-spot-serum-15-2/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/nl/p/laneige/radian-c-vitamin-spot-serum-15-2/for/acne-prone-skin): Superior (this page)
- [Skin with dark spots](https://lovi.care/skincare/nl/p/laneige/radian-c-vitamin-spot-serum-15-2/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/nl/p/laneige/radian-c-vitamin-spot-serum-15-2/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/laneige/radian-c-vitamin-spot-serum-15-2/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/laneige/radian-c-vitamin-spot-serum-15-2/for/oily-acne-prone-skin): High

## Key ingredients

Ascorbic Acid, Niacinamide, Tranexamic Acid, Glutathione, Licorice Root Extract

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- A multi-component dissolving microneedle patch loaded with glabridin, 3-O-ethyl-L-ascorbic acid, and tranexamic acid effectively reduced chloasma and age spots while demonstrating safety in clinical evaluation, alongside significant antioxidant, anti-tyrosinase, and melanin-reduction effects in vitro and in vivo. ([Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Glutathione amino acid precursors effectively increase cellular glutathione levels, reducing oxidative stress, ATP depletion, and DNA damage in human keratinocytes, clinical subjects, and ex vivo skin compared to controls. ([Journal of the European Academy of Dermatology and Venereology, 2024](https://pubmed.ncbi.nlm.nih.gov/38189670/))
- Topical oxidized glutathione significantly decreases the skin melanin index and improves moisture content, smoothness, wrinkle formation, and elasticity compared to placebo in healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25378941/))
- Topical glutathione improves hyperpigmentation, reduces ultraviolet-induced erythema and wrinkles, decreases transepidermal water loss, and enhances antioxidant capacity. ([The Journal of Clinical and Aesthetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41416233/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))

## What reviewers say

Based on limited data, users frequently praise this serum for effectively fading dark spots and brightening skin tone, noting it is gentle enough for sensitive skin. A significant number of reviewers report issues with the product oxidizing quickly, and some find the scent unpleasant or the finish sticky. There are also moderate reports of packaging issues and the product quantity being small for the price.

- Liked: Brightens skin tone (often mentioned)
- Liked: Fades dark spots (often mentioned)
- Disliked: Rapid oxidation (often mentioned)
- Liked: Fast absorption (sometimes noted)
- Liked: Gentle formula (sometimes noted)
- Disliked: Packaging issues (sometimes noted)
- Disliked: Small quantity (sometimes noted)
- Disliked: Sticky/oily finish (sometimes noted)
- Disliked: Unpleasant scent (sometimes noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes LANEIGE Radian-C Vitamin Spot Serum one of the best fits for acne-prone skin?

This serum is one of the best fits for acne-prone skin because high concentrations of Ascorbic Acid and 3-O-Ethyl Ascorbic Acid brighten uneven skin tone while offering antioxidant and anti-inflammatory benefits. Niacinamide and Tranexamic Acid further support this by reducing inflammation for clearer skin, while soothing ingredients like Centella Asiatica Stem Extract minimize any potential irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/)

### Which ingredients make this serum a good fit for acne-prone skin?

This serum is a great fit because of Ascorbic Acid, 3-O-Ethyl Ascorbic Acid, Niacinamide, and Tranexamic Acid, which help brighten skin and reduce inflammation. Tocopherol and Centella Asiatica Stem Extract Flower Leaf are also included to calm acne-prone skin and minimize irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37571190/)

### What does Vitamin C do for acne-prone skin?

Vitamin C helps brighten skin, smooth out uneven tones, and fade dark spots left behind by breakouts. It is also packed with antioxidants that may help protect acne-prone skin from everyday environmental stress.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37128827/), [Journal of Drugs in Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/39231081/)

### What does Niacinamide do for acne-prone skin?

Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/), [Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/38725769/)

### Where does this serum go in a skincare routine for acne-prone skin?

This treatment serum goes in the evening routine after cleansing and before moisturizing, though some can also be used in the morning or twice a day. It is very well suited for acne-prone skin because it combines powerful brightening vitamins with soothing ingredients that help keep your skin clear while minimizing irritation.

### Can I use this serum with retinol, and in what order?

You can use this treatment in your routine with retinol by applying the retinol first and following with this serum, or by using retinol at night and this serum in the morning. This formula has a very good safety profile with soothing ingredients that are unlikely to cause irritation when combined thoughtfully.

### How often should I use this serum?

This treatment serum works best in your evening routine, applied once a day. Lovi routines place treatments in the evening for simplicity and extra safety around sun exposure.

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is unlikely to clog pores or cause breakouts for acne-prone skin because it relies on soothing and brightening ingredients like vitamin C, niacinamide, and centella extract that help calm redness and clear uneven tone. It also has a safe profile with no harsh components that typically trigger irritation or congestion.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (limonene, parfum, linalool, and citral).

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/nl/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — €10.20 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — €35.80 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/nl/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — €160.00 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/nl/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — €19.90 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — €19.20 at Amazon

## Where to buy

No store in Netherlands has a checked price for this product, so the page shows none.

## Ingredients

Water, Ascorbic Acid, Propanediol, Dimethicone, Dipropylene Glycol, Tromethamine, 3-O-Ethyl Ascorbic Acid, Squalane, Panthenol, Sodium Chloride, Acetyl Glucosamine, Limonene, Caffeine, Sodium Hyaluronate, Sodium Sulfite, Disodium Edta, Glutathione, Parfum, Gardenia Florida Fruit Extract, Dextrin, Linalool, Citral, Butylene Glycol, Arginine, Xanthan Gum, Niacinamide, Tranexamic Acid, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Tocopherol, Methyl Trimethicone, Carthamus Tinctorius Seed Oil, 1,2-Hexanediol, Ethylhexylglycerin, Centella Asiatica Stem Extract Flower Leaf
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/laneige/radian-c-vitamin-spot-serum-15-2/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/laneige/radian-c-vitamin-spot-serum-15-2/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/laneige/radian-c-vitamin-spot-serum-15-2/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/laneige/radian-c-vitamin-spot-serum-15-2/for/acne-prone-skin
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- Netherlands: https://lovi.care/skincare/nl/p/laneige/radian-c-vitamin-spot-serum-15-2/for/acne-prone-skin (this page)
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