# La Roche-Posay Effaclar Ultra Concentrated Serum for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/nl/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [La Roche-Posay](https://lovi.care/skincare/nl/brands/la-roche-posay)
Category: [Exfoliants](https://lovi.care/skincare/nl/best/exfoliators)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best products for sensitive skin.

## Why this fit

- Offers excellent exfoliation for your normal skin due to glycolic acid and salicylic acid, which effectively decongest pores and smooth texture without causing irritation.
- While beneficial for general skin health, the formula's exfoliating properties are not specifically targeted to address your primary concerns of redness and irritation.
- The product is safe for your normal skin with sensitivity, as it lacks harsh ingredients and poses no risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/nl/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/nl/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/nl/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/nl/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/nl/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/nl/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/oily-acne-prone-skin): High

## Key ingredients

Glycolic Acid, Salicylic Acid, Niacinamide, Biosaccharide Gum-1, Capryloyl Salicylic Acid

## What the research says

- Twice daily application of a multitargeted dermocosmetic cream provided comparable efficacy to benzoyl peroxide 5% gel in reducing inflammatory, non-inflammatory, and total lesions in 150 Caucasian subjects with mild-to-moderate acne over 56 days, while demonstrating superior skin tolerability. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/))
- Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/))
- The use of a salicylic acid-based dermocosmetic significantly reduces the needed quantity of benzoyl peroxide without impacting efficacy in mild to moderate acne, and as maintenance post-benzoyl peroxide allows a significant reduction of acne relapse compared to vehicle. ([Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/38051857/))
- Repeated short-contact 70% glycolic acid peels provided superior results in atrophic acne scars compared to daily low-strength glycolic acid cream or placebo in 58 women over 24 weeks. ([International Journal of Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/11095203/))
- Serial glycolic acid peels combined with a modified Kligman formula significantly reduced facial PIH severity in Indian patients compared to the modified Kligman formula alone. ([Dermatologic Surgery, 2017](https://pubmed.ncbi.nlm.nih.gov/28114204/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Capryloyl salicylic acid peel reduced fine lines, wrinkles, and hyperpigmentation comparably to glycolic acid peel in 44 female volunteers, with no statistically significant differences between the two treatments. ([Journal of Cosmetic Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19146601/))
- Combining a salicylic acid and lipohydroxy acid facial serum and mask improved closed comedones and acne severity significantly more than serum alone in adults with acne over 8 weeks, with no adverse reactions reported. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36999489/))
- Parity was demonstrated between an OTC BPO 5.5% formulation with lipohydroxy acid and tretinoin cream 0.025% versus prescription clindamycin 1%-BPO 5% gel and tretinoin cream 0.025% in participants with mild to moderate acne vulgaris at 12 weeks. ([Cutis, 2012](https://pubmed.ncbi.nlm.nih.gov/22838094/))

## What reviewers say

Based on a very large amount of data, this serum is highly rated by users with oily, acne-prone, and textured skin for its ability to rapidly reduce breakouts and smooth skin surface. While effective for many in clearing congestion and tightening pores, a notable minority of users experience purging, stickiness, or irritation due to its potent acid blend.

- Liked: Reduces acne (mostly mentioned)
- Liked: Minimizes pores (often mentioned)
- Liked: Smoother texture (often mentioned)
- Liked: Controls oil (sometimes noted)
- Disliked: Drying and irritation (sometimes noted)
- Disliked: Initial breakouts (sometimes noted)
- Disliked: Sticky texture (sometimes noted)
- Disliked: Strong scent (rarely noted)

## How to apply

- Use your exfoliant PM once a week to help with redness and irritation. Start slowly and only increase frequency if your skin feels happy and comfortable.
- Apply the exfoliant after cleansing and toner , but always before your moisturizer . This ensures the product absorbs properly into the skin.
- Gently press 2-3 drops of the exfoliant into your skin without rubbing . Let it absorb for a minute before moving on.
- Since your skin is sensitive , apply the exfoliant on completely dry skin for the best tolerance. This helps prevent any extra stinging or discomfort.
- Always do a patch test before your first use and avoid the delicate eye area .
- Video: https://storage.pora.ai/028e5e793422a3b665c02ff502cf5a68.mp4

## Questions and answers

### What makes Effaclar Ultra Concentrated Serum a great fit for sensitive skin?

La Roche-Posay Effaclar Ultra Concentrated Serum is a great fit because it contains glycolic acid and salicylic acid to clear out pores and smooth texture without causing irritation on sensitive skin. It is safe for this skin type because it lacks harsh ingredients and poses no risk of irritation.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/), [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/)

### Which ingredients make this serum a good fit for sensitive skin?

This serum is a great fit for your sensitive skin because it contains glycolic acid, salicylic acid, and capryloyl salicylic acid, which effectively smooth texture and decongest pores. It also includes niacinamide and biosaccharide gum-1 to help keep your skin calm and comfortable.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/), [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/)

### What does Glycolic Acid do for sensitive skin?

Glycolic acid can be too harsh for sensitive skin, leaving it dry and irritated, so this type of skin needs a gentler exfoliating ingredient and calming plant extracts to keep the skin barrier safe and comfortable.
Sources: [Cutaneous and Ocular Toxicology, 2022](https://pubmed.ncbi.nlm.nih.gov/35920724/)

### What does Salicylic Acid do for sensitive skin?

Salicylic acid may cause irritation on sensitive skin, so it requires careful use and good sun protection to keep skin comfortable. A product for this skin type needs gentle, soothing ingredients and a mild formula that respects the skin barrier.
Sources: [The British Journal of Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10233334/), [International Journal of Toxicology, 2003](https://pubmed.ncbi.nlm.nih.gov/14617432/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in your evening routine, applied after your cleanser and soothing toner and before your moisturizer. Lovi routines start exfoliating steps once a week, and people who tolerate them well and see good results may carefully use them more often.

### Can I use this serum with retinol, and in what order?

This serum can be used alongside retinol by applying it during your evening routine after cleansing and toning, and before moisturizing. Because both ingredients are strong, using them together may cause dryness, so it is best to introduce them slowly or alternate nights to keep your skin calm and comfortable.

### How often should I use this serum?

Start using this serum once a week in your evening routine, and if your sensitive skin tolerates it well and shows good results, you can carefully use it more often. This approach helps you build tolerance safely while smoothing your skin texture and decongesting pores.

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum may cause initial breakouts or purging when you first start using it due to the exfoliating ingredients that clear out deep congestion. However, it is unlikely to cause lasting irritation on sensitive skin since it is formulated without harsh irritants.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37941097/), [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/)

### Is this serum fragrance-free and alcohol-free?

It contains fragrance (parfum) and drying alcohol (alcohol denat).

## Alternatives for sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/nl/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — €160.00 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — €35.50 at Amazon
- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/nl/p/cosrx/the-vitamin-c-23-serum/for/sensitive-skin) — High fit — €19.00 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — €21.95 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/nl/p/skin1004/centella-asiatica-toning-toner/for/sensitive-skin) — Superior fit — €17.96 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/nl/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — €19.79 at Amazon

## Where to buy

- Amazon.nl: €33.80 (https://www.amazon.nl/dp/B08H81SZKH?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €38.64 (https://www.lookfantastic.nl/p/la-roche-posay-effaclar-ultra-concentrate-serum-for-blemish-prone-skin-30ml/12667336/)
Prices checked 10 Oct – 5 Nov 2026.

## Ingredients

Water, Alcohol Denat, Propanediol, Glycolic Acid, Niacinamide, Dimethyl Isosorbide, Pentylene Glycol, Salicylic Acid, Sodium Hydroxide, Peg-60 Hydrogenated Castor Oil, Hydroxyethylpiperazine Ethane Sulfonic Acid, Citric Acid, Peg-30 Glyceryl Cocoate, Capryloyl Salicylic Acid, Biosaccharide Gum-1, Maltodextrin, Phytic Acid, Polyquaternium-10, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/sensitive-skin (this page)
- Spain: https://lovi.care/skincare/es/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/effaclar-ultra-concentrated-serum/for/sensitive-skin
