# La Roche-Posay Cicaplast B5 Serum for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/nl/p/la-roche-posay/cicaplast-b5-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [La Roche-Posay](https://lovi.care/skincare/nl/brands/la-roche-posay)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/nl/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate suitability for combination skin as glycerin and panthenol provide humectant action and support skin barrier repair, though it lacks targeted ingredients for acne and breakouts.
- The formula provides general hydration and soothing benefits, which you may notice, but these are not the primary concerns for your acne-prone skin.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components like panthenol and glycerin.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/la-roche-posay/cicaplast-b5-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/nl/p/la-roche-posay/cicaplast-b5-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/nl/p/la-roche-posay/cicaplast-b5-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/nl/p/la-roche-posay/cicaplast-b5-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/nl/p/la-roche-posay/cicaplast-b5-serum/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/nl/p/la-roche-posay/cicaplast-b5-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/nl/p/la-roche-posay/cicaplast-b5-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/la-roche-posay/cicaplast-b5-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/la-roche-posay/cicaplast-b5-serum/for/oily-acne-prone-skin): High

## Key ingredients

B5 Panthenol, Thermal Water, Sodium Hyaluronate, Glycerin, Dimethicone

## What the research says

- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Malaysian thermal spring water as an adjunct to standard acne therapy improved skin hydration, reduced dryness and stinging, enhanced overall tolerability, and improved the acne disability index in patients with mild to moderate acne. ([The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Balneotherapy with thermal water altered specific skin microbiota at genus and species levels in healthy female volunteers compared to tap water, which produced no significant microbiome changes. ([Life, 2023](https://pubmed.ncbi.nlm.nih.gov/36983902/))
- A 2% Sphingomonas xenophaga ferment extract cream applied twice daily for 4 weeks significantly decreased facial vascular disorder scores compared to vehicle in 86 Caucasian female subjects, alongside dose-dependent inhibition of pre-kallikrein activity in vitro. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/40545753/))
- A formulation containing vitamin C, biopeptides, hyaluronic acid, and mineralizing water accelerated cell turnover to 17.1 days versus 19.2 days for untreated skin, and reduced crow's-feet, forehead, and nasolabial folds by 9%, 11%, and 5% respectively after 28 days in female subjects. ([International Journal of Cosmetic Science, 2021](https://pubmed.ncbi.nlm.nih.gov/33038010/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))

## Why other moisturizers fit acne-prone skin better

- Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients. ([The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))

## What reviewers say

This serum is widely praised as a rescue product for compromised skin barriers, effectively soothing redness, dehydration, and irritation. Most users with dry or sensitive skin report rapid healing and improved texture. A minority experience stinging upon application or find the formula too tacky and the dropper packaging messy.

- Liked: Intense barrier repair (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Liked: Soothing for sensitive skin (often mentioned)
- Disliked: Poor packaging design (often mentioned)
- Liked: Improves skin texture (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Unpleasant texture/finish (sometimes noted)
- Disliked: Caused irritation/stinging (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Cicaplast B5 Serum work for acne-prone skin?

La Roche-Posay Cicaplast B5 Serum works as an average fit for acne-prone skin because it provides general hydration and calms irritation with panthenol and glycerin, but it lacks targeted ingredients for breakouts. To fit acne-prone skin better, a moisturizing treatment needs ingredients like niacinamide, peptides, or centella asiatica to address blemishes while keeping skin balanced.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this serum a good fit for acne-prone skin?

This serum works for acne-prone skin because B5 Panthenol and Thermal Water help soothe and hydrate, though other products fit this skin type better. To truly fit acne-prone skin, a moisturizing treatment needs ingredients like Niacinamide, Hydrolyzed Hyaluronic Acid, peptides, or Centella Asiatica to target breakouts and blemishes effectively without clogging pores.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/)

### What does Panthenol do for acne-prone skin?

Panthenol helps calm red and irritated skin while supporting the skin barrier with excellent suitability for acne-prone skin. It may also help regulate oil and improve hydration without causing negative reactions.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/)

### What does Thermal Water do for acne-prone skin?

Thermal water helps calm acne-prone skin by reducing irritation, redness, and dryness while supporting the skin barrier. It is unlikely to cause irritation and may improve overall skin comfort when used alongside your regular acne routine.
Sources: [The Medical Journal of Malaysia, 2024](https://pubmed.ncbi.nlm.nih.gov/38553920/), [Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37338719/)

### Where does this serum go in a skincare routine for acne-prone skin?

This serum goes in your evening routine, after cleansing and before moisturizing. It has a very safe formula with soothing ingredients like panthenol and glycerin, but acne-prone skin needs a product of this type that also includes targeted ingredients for breakouts.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to help keep your skin calm and hydrated while you use retinol. This product of this type needs barrier-repairing ingredients like ceramides and soothing agents to support acne-prone skin during retinization.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### How often should I use this serum?

You can use this serum in the evening as part of your routine, as treatments fit best at night for simplicity and safety around sun exposure. Some serums may also be used in the morning or twice a day if your skin tolerates them well.

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is unlikely to clog pores or cause breakouts because it has a very safe formula with soothing ingredients that do not irritate your skin. However, since it lacks targeted ingredients for acne and breakouts, acne-prone skin needs products that also include blemish-fighting ingredients like salicylic acid or benzoyl peroxide.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Can I use this serum around the eyes or on my body?

You can use this serum safely around the eyes and on the body because its gentle formula has a very high safety profile. It helps keep thin and body skin soft and hydrated without causing irritation.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Is this serum fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol denat).

## Alternatives for acne-prone skin

- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/nl/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/acne-prone-skin) — High fit — €37.80 at Amazon
- [MISSHA Super Aqua Ultra Hyalron Ampoule](https://lovi.care/skincare/nl/p/missha/super-aqua-ultra-hyalron-ampoule/for/acne-prone-skin) — Average fit — €22.80 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/nl/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/acne-prone-skin) — High fit — €26.90 at Notino

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/nl/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — €19.90 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/nl/p/d-alba/piedmont-waterfull-mild-sunscreen/for/acne-prone-skin) — Superior fit — €16.75 at Amazon

## Where to buy

- Amazon.nl: €33.75 (https://www.amazon.nl/dp/B0C5RTTF6Q?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- Notino: €35.10 (https://www.notino.nl/la-roche-posay/cicaplast-baume-b5-set-voor-het-kalmeren-van-de-huid/p-16387493/)
- Lookfantastic: €38.64 (https://www.lookfantastic.nl/p/la-roche-posay-cicaplast-b5-face-serum-for-dehydrated-skin-30ml/14239221/)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Water, Panthenol, Glycerin, Alcohol Denat, Dimethicone, Hydroxyethylpiperazine Ethane Sulfonic Acid, Peg-20 Methyl Glucose Sesquistearate, Sodium Hyaluronate, Ammonium Polyacryloyldimethyl Taurate, Caprylyl Glycol, Vitreoscilla Ferment, Citric Acid, Xanthan Gum, Octyldodecanol, Tocopherol, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/la-roche-posay/cicaplast-b5-serum/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/la-roche-posay/cicaplast-b5-serum/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/la-roche-posay/cicaplast-b5-serum/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/la-roche-posay/cicaplast-b5-serum/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/la-roche-posay/cicaplast-b5-serum/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/la-roche-posay/cicaplast-b5-serum/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/la-roche-posay/cicaplast-b5-serum/for/acne-prone-skin (this page)
- Spain: https://lovi.care/skincare/es/p/la-roche-posay/cicaplast-b5-serum/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/la-roche-posay/cicaplast-b5-serum/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/la-roche-posay/cicaplast-b5-serum/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/la-roche-posay/cicaplast-b5-serum/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/la-roche-posay/cicaplast-b5-serum/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/la-roche-posay/cicaplast-b5-serum/for/acne-prone-skin