# Jole Azelaic Acid 10% Serum for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/nl/p/jole/azelaic-acid-10-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Jole](https://lovi.care/skincare/nl/brands/jole)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for sensitive skin.

## Why this fit

- Highly suitable for your normal skin, this serum contains azelaic acid and niacinamide to help regulate oil and reduce inflammation, while bisabolol soothes redness and irritation.
- The inclusion of squalane and glyceryl glucoside provides additional hydration, supporting your skin's barrier function.
- The formula is safe for your sensitive skin, as it lacks harsh ingredients and includes soothing components like niacinamide and bisabolol.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/jole/azelaic-acid-10-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/nl/p/jole/azelaic-acid-10-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/nl/p/jole/azelaic-acid-10-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/nl/p/jole/azelaic-acid-10-serum/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/nl/p/jole/azelaic-acid-10-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/nl/p/jole/azelaic-acid-10-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/nl/p/jole/azelaic-acid-10-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/jole/azelaic-acid-10-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/jole/azelaic-acid-10-serum/for/oily-acne-prone-skin): High

## Key ingredients

Azelaic Acid, Niacinamide, Squalane, Bisabolol, Allantoin

## What the research says

- Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo. ([Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/))
- Topical application of glyceryl glucoside significantly increased AQP3 mRNA levels and reduced transepidermal water loss compared with vehicle-controlled areas in volunteer subjects. ([Skin Pharmacology and Physiology, 2012](https://pubmed.ncbi.nlm.nih.gov/22584263/))
- Topical oil-in-water and water-in-oil emulsions containing glyceryl glucoside, natural moisturizing factors, and ceramide significantly improved skin hydration and barrier function while reducing visible dryness and tactile roughness in subjects with very dry skin compared to untreated sites and vehicles. ([The Journal of Clinical and Aesthetic Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22916312/))
- Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/))
- Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks. ([Journal of the European Academy of Dermatology and Venereology, 2023](https://pubmed.ncbi.nlm.nih.gov/36729399/))
- Topical administration of 20% azelaic acid cream and 5% tranexamic acid solution comparably improved acne-related postinflammatory hyperpigmentation in patients with acne vulgaris, while tranexamic acid demonstrated a significantly better safety profile at week 4. ([Journal of Research in Medical Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/37213446/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Application of an alpha-bisabolol-containing cream produced a significant skin-lightening effect in pigmented skin compared to a vehicle control in the majority of female subjects after 8 weeks. ([International Journal of Cosmetic Science, 2010](https://pubmed.ncbi.nlm.nih.gov/20642768/))
- The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate reduces UVB-induced PGE2, inflammatory cytokines, and mitochondrial superoxide in human epidermal keratinocytes. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38433250/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))

## What reviewers say

Users highly recommend this serum for acne-prone and sensitive skin, noting its strong effectiveness in clearing active breakouts, reducing inflammation, and fading post-acne hyperpigmentation. The lightweight formula absorbs quickly and improves overall skin texture, though a small number of users experienced temporary dryness or a brief purging phase.

- Liked: Reduces acne breakouts (mostly mentioned)
- Liked: Fades post-acne marks (often mentioned)
- Liked: Absorbs very quickly (sometimes noted)
- Liked: Calms skin redness (sometimes noted)
- Disliked: Causes mild dryness (rarely noted)
- Disliked: Faulty pump dispenser (rarely noted)
- Disliked: Initial skin purging (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Jole Jole Azelaic Acid 10% Serum a great fit for sensitive skin?

This serum is a great fit because it uses azelaic acid and niacinamide to calm redness and irritation without harsh ingredients. Soothing components like bisabolol and hydrating ingredients like squalane and glyceryl glucoside help keep sensitive skin comfortable.
Sources: [Skin Pharmacology and Physiology, 2012](https://pubmed.ncbi.nlm.nih.gov/22584263/), [The Journal of Clinical and Aesthetic Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22916312/)

### Which ingredients make this serum a good fit for sensitive skin?

This serum is a great fit for sensitive skin because it features soothing components like bisabolol and niacinamide to calm redness and irritation without harsh ingredients. It also includes squalane and glyceryl glucoside to support your skin barrier and keep your skin hydrated.
Sources: [Skin Pharmacology and Physiology, 2012](https://pubmed.ncbi.nlm.nih.gov/22584263/), [The Journal of Clinical and Aesthetic Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22916312/)

### What does Azelaic Acid do for sensitive skin?

Azelaic acid helps calm sensitive, red, or easily irritated skin by soothing inflammation and reducing redness. It is generally well-tolerated and is unlikely to cause severe reactions, making it a gentle option for skin that flares up easily.
Sources: [Experimental Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20545756/), [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/21637903/)

### What does Niacinamide do for sensitive skin?

Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
Sources: [Cutis, 2005](https://pubmed.ncbi.nlm.nih.gov/16209160/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in the evening routine after your cleansing and toning steps, followed by a moisturizer. Putting treatments in the evening provides simplicity and extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first, waiting for it to absorb, and then following with your retinol. Because this formula is free of harsh ingredients and includes calming components like niacinamide and bisabolol, it is unlikely to irritate your sensitive skin.

### How often should I use this serum?

This treatment is used in the evening once a week to start, and people who tolerate it well and see good results may carefully use it more often. It helps calm redness and soothe sensitive skin while supporting hydration and barrier function.

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores, and initial skin purging is low for sensitive skin. The formula helps calm redness and irritation while supporting your skin barrier with soothing ingredients.
Sources: [Skin Pharmacology and Physiology, 2012](https://pubmed.ncbi.nlm.nih.gov/22584263/), [The Journal of Clinical and Aesthetic Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22916312/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/nl/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — €160.00 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — €35.50 at Amazon
- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/nl/p/cosrx/the-vitamin-c-23-serum/for/sensitive-skin) — High fit — €19.00 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — €21.95 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/nl/p/skin1004/centella-asiatica-toning-toner/for/sensitive-skin) — Superior fit — €17.96 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/nl/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — €19.79 at Amazon

## Where to buy

No store in Netherlands has a checked price for this product, so the page shows none.

## Ingredients

Water, Ethoxydiglycol, Azelaic Acid, Niacinamide, Glyceryl Glucoside, Squalane, Bisabolol, Allantoin, Ammonium Acryloyldimethyltaurate Vp Copolymer, Valine, Proline, Lysine, Serine, Sorbitan Caprylate, 1,2 Propanediol, Benzoic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/jole/azelaic-acid-10-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/jole/azelaic-acid-10-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/jole/azelaic-acid-10-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/jole/azelaic-acid-10-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/jole/azelaic-acid-10-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/jole/azelaic-acid-10-serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/jole/azelaic-acid-10-serum/for/sensitive-skin (this page)
- Spain: https://lovi.care/skincare/es/p/jole/azelaic-acid-10-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/jole/azelaic-acid-10-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/jole/azelaic-acid-10-serum/for/sensitive-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/jole/azelaic-acid-10-serum/for/sensitive-skin