# IT'S SKIN Power 10 Formula VC Effector for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/nl/p/it-s-skin/power-10-formula-vc-effector/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: IT'S SKIN
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for combination skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your combination skin due to Ascorbyl Tetraisopalmitate and Camellia Sinensis Leaf Extract, which offer antioxidant activity and seboregulation to address oily shine.
- The product provides excellent brightening and evening of skin tone, though it lacks specialized ingredients for enhanced oil control.
- The safety profile is excellent, with no risks of irritation for your combination skin due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/it-s-skin/power-10-formula-vc-effector/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/nl/p/it-s-skin/power-10-formula-vc-effector/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/nl/p/it-s-skin/power-10-formula-vc-effector/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/nl/p/it-s-skin/power-10-formula-vc-effector/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/nl/p/it-s-skin/power-10-formula-vc-effector/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/nl/p/it-s-skin/power-10-formula-vc-effector/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/nl/p/it-s-skin/power-10-formula-vc-effector/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/it-s-skin/power-10-formula-vc-effector/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/it-s-skin/power-10-formula-vc-effector/for/oily-acne-prone-skin): High

## Key ingredients

Ascorbic Acid Ascorbyl Tetraisopalmitate, Glycerin, Polyglutamic Acid, Camellia Sinensis Leaf Extract, Butylene Glycol

## What the research says

- An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/))
- Topical formulations containing ascorbyl tetraisopalmitate, coenzyme Q10, green tea polyphenols, and resveratrol reduced the release of inflammatory cytokines and attenuated inflammatory signs compared to untreated skin and vehicle in 25 Japanese volunteers exposed to sodium dodecyl sulfate. ([European Journal of Pharmaceutics and Biopharmaceutics, 2017](https://pubmed.ncbi.nlm.nih.gov/28385617/))
- Enzymatic alpha glucosylation of EGCG yielded EGCG-G1, which enhanced epidermal penetration, decreased melanogenesis through down-regulation of 13 genes including MITF, stimulated skin Lactobacillus growth, and decreased hyperpigmented spots while increasing skin brightness and homogeneity compared to EGCG and vitamin C across a large panel of phototypes. ([Molecules, 2024](https://pubmed.ncbi.nlm.nih.gov/39598779/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical ascorbic acid application resulted in a statistically significant improvement in Ra and shadows north-south facial axis values as well as clinical, photographic, and patient self-appraisal scores compared with vehicle control in nineteen patients with mild to moderately photodamaged facial skin. ([Archives of Otolaryngology--head & Neck Surgery, 1999](https://pubmed.ncbi.nlm.nih.gov/10522500/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Curcumin-loaded polyglutamic acid and gum arabic electrospun nanofibers accelerated wound healing, increased TGF-beta1 and VEGF expression, reduced inflammatory factors, and enhanced re-epithelialization and tissue regeneration in a mouse model with acute full-thickness skin defects. ([International Journal of Biological Macromolecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38554903/))
- Polyglutamic acid and polylysine composite hydrogels promote wound repair and hemostasis through high water absorption, bioadhesion, calcium ion-mediated coagulation factor activation, and inherent antibacterial properties in a deep skin defect model. ([Macromolecular Bioscience, 2021](https://pubmed.ncbi.nlm.nih.gov/33656254/))
- Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction. ([Journal of Clinical and Diagnostic Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28384900/))
- Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/))
- Topical application of green tea extract encapsulated chitosan microparticles improved skin elasticity, melanin index, and facial wrinkles compared to a placebo in female volunteers without causing skin irritation. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34965006/))

## What reviewers say

Based on a very large amount of data, this Vitamin C serum is frequently praised for its brightening effects and hydrating properties, making it a popular choice for those with dry or dull skin. It is also noted for being gentle and suitable for sensitive or beginner users. Some users experience a sticky finish or find the results take a considerable amount of time to become apparent, and a few report issues with the packaging or breakouts. The potency is considered mild by some, not ideal for those seeking significant anti-aging benefits.

- Liked: Brightens complexion (often mentioned)
- Liked: Hydrating formula (often mentioned)
- Liked: Gentle on skin (sometimes noted)
- Liked: Pleasant texture (sometimes noted)
- Disliked: Slow results (sometimes noted)
- Liked: Citrus scent (rarely noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Low potency (rarely noted)
- Disliked: Packaging design (rarely noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes IT'S SKIN Power 10 Formula VC Effector a great fit for combination skin?

IT'S SKIN Power 10 Formula VC Effector is a great fit for combination skin because Ascorbyl Tetraisopalmitate and Camellia Sinensis Leaf Extract help control oily shine and even out skin tone. It is very safe and unlikely to cause irritation, thanks to soothing ingredients and the lack of harsh components.
Sources: [Molecules, 2024](https://pubmed.ncbi.nlm.nih.gov/39598779/), [Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/)

### Which ingredients make this serum a good fit for combination skin?

Ascorbyl Tetraisopalmitate and Camellia Sinensis Leaf Extract make this serum a great fit for your combination skin. These ingredients help control extra oil and protect your skin with antioxidants, while being very gentle and unlikely to cause irritation.
Sources: [Molecules, 2024](https://pubmed.ncbi.nlm.nih.gov/39598779/), [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/)

### What does Ascorbic Acid do for combination skin?

Ascorbic acid helps brighten skin tone and smooth out rough areas on combination skin. It is unlikely to cause irritation when used regularly, and it helps protect against everyday environmental stress.
Sources: [Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35064615/)

### What does Glycerin do for combination skin?

Glycerin helps keep combination skin soft and smooth by pulling moisture in and keeping it there. It improves hydration and supports your skin barrier, which is unlikely to cause irritation.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this serum go in a skincare routine for combination skin?

This treatment serum goes in your evening routine after cleansing and toning, and before moisturizing. Putting treatments in the evening keeps things simple and provides extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this treatment with retinol by applying the vitamin C serum in your morning routine and your retinol at night to avoid overwhelming your combination skin. This product is very gentle, but using them at different times of day helps prevent potential irritation.

### How often should I use this serum?

You can use this treatment serum in your evening routine. It is a great fit for your combination skin and helps brighten tone and manage oily shine with a very low risk of irritation.
Sources: [Molecules, 2024](https://pubmed.ncbi.nlm.nih.gov/39598779/), [Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to cause breakouts on combination skin due to its very safe makeup and soothing ingredients, though a small number of shoppers have reported breakouts. It helps balance oil and brighten skin while keeping irritation risks low.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/nl/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — €10.20 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — €35.80 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/nl/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — €474.90 at Amazon

## Pairs well with

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/nl/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — €16.50 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/combination-skin) — Superior fit — €19.20 at Amazon

## Where to buy

No store in Netherlands has a checked price for this product, so the page shows none.

## Ingredients

Water, Butylene Glycol, Glycerin, Polyglutamic Acid, Ascorbyl Tetraisopalmitate, Peg-60 Hydrogenated Castor Oil, Carbomer, Methylparaben, Triethanolamine, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Camellia Sinensis Leaf Extract, Chlorphenesin, Disodium Edta, Dipropylene Glycol, Ethyl Hexanediol, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/it-s-skin/power-10-formula-vc-effector/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/it-s-skin/power-10-formula-vc-effector/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/it-s-skin/power-10-formula-vc-effector/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/it-s-skin/power-10-formula-vc-effector/for/combination-skin
- France: https://lovi.care/skincare/fr/p/it-s-skin/power-10-formula-vc-effector/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/it-s-skin/power-10-formula-vc-effector/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/it-s-skin/power-10-formula-vc-effector/for/combination-skin (this page)
- Spain: https://lovi.care/skincare/es/p/it-s-skin/power-10-formula-vc-effector/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/it-s-skin/power-10-formula-vc-effector/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/it-s-skin/power-10-formula-vc-effector/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/it-s-skin/power-10-formula-vc-effector/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/it-s-skin/power-10-formula-vc-effector/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/it-s-skin/power-10-formula-vc-effector/for/combination-skin