HISTOLAB Soft Deep Cleansing Enzyme Powder Wash for acne-prone skin
Papaya Enzyme
Rice Powder
Baking Soda
Camellia Sinensis Extract
Ascorbic AcidHigh
- HighCombination Skin Fit
- AverageEffectiveness
- ExcellentSafety
A great choice for acne-prone skin; a few products fit it even better.
This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers excellent cleansing for your combination skin, as Sodium Lauroyl Glutamate and Sodium Cocoyl Isethionate effectively remove impurities and excess oil from pores. Papain and bromelain provide moderate enzymatic exfoliation, which helps manage oiliness and promotes smoother skin, though it may not be specialized enough for severe acne.
- Allantoin and Tocopherol Vitamin E offer soothing benefits, minimizing irritation potential for your acne-prone skin.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.
How to apply
- Use your enzyme powder cleanser as part of your PM weekly routine. Start by using it once a week and build up slowly if your skin is happy.
- Place this step after your regular cleanser and before applying your hydrating toner. Follow the weekly routine order for the best results.
- Mix the powder with a little water in your hands to create a soft foam. Gently massage onto your face and avoid rubbing too hard.
- Apply the enzyme powder cleanser on slightly damp skin to help activate the formula evenly. Make sure your face is clean before applying.
- Avoid the sensitive eye area during application. Do a patch test first and do not combine this with strong acids on the same night.
People Say
★4.0Overall rating based on 100+ reviewsBased on limited available data, users find this enzymatic cleanser to be gentle and effective, leaving skin soft and smooth without stripping natural oils. It is particularly beneficial for oily and acne-prone skin, helping to manage sebum and unclog pores. Some users note a learning curve for lathering the powder format.
Highlights
Gentle Exfoliation Often Mentioned
- “leaves skin soft”
- “non-stripping cleanse”
- “gentle enzyme action”
Travel-Friendly Often Mentioned
- “perfect for travel”
- “compact size”
- “easy to pack”
Good for Oily/Acne Skin Sometimes Noted
- “reduces closed comedones”
- “calms oily skin”
- “good for breakouts”
Post-Wash Feel Sometimes Noted
- “squeaky clean but soft”
- “refreshed feeling”
- “smooth complexion”
Lathering difficulty Sometimes Noted
- “doesn't lather well”
- “hard to foam”
- “needs mixing effort”
Availability Rarely Noted
- “inconvenient to buy”
- “shipping takes long”
- “niche product”
Price & Size Rarely Noted
- “wish it was larger”
- “expensive for size”
- “hard to find”
Scent Rarely Noted
- “acquired taste”
- “scent is disappointing”
- “odd smell at first”
Sources: lovi.care, histolab.ca, ubuy.com, hwahae.co.kr, ebay.com, gosupps.com, and more
Questions and answers
What makes HISTOLAB Enzyme Powder Wash a great fit for acne-prone skin?
HISTOLAB Soft Deep Cleansing Enzyme Powder Wash is a great fit for acne-prone skin because it gently clears away excess oil and impurities while providing mild enzymatic exfoliation to keep skin smooth. Soothing ingredients like allantoin and vitamin E help keep irritation low, giving it an excellent safety profile for sensitive or breakout-prone skin.
Giornale Italiano Di Dermatologia E Venereologia, 2015Journal of Cosmetic Science, 2007
Which ingredients make this cleanser a good fit for acne-prone skin?
Sodium Lauroyl Glutamate and Sodium Cocoyl Isethionate make this cleanser a great fit by washing away pore-clogging oil, while papain and bromelain gently smooth the skin. Allantoin and vitamin E help calm irritation, making it very safe for your skin type.
What does Papaya Enzyme do for acne-prone skin?
Papaya enzyme gently removes dead surface buildup to help clear pores and smooth out rough texture. It helps keep skin calm and is unlikely to cause irritation when used as directed.
What does Rice Powder do for acne-prone skin?
Rice Powder helps absorb excess oil and calms dry, irritated areas while being very unlikely to irritate acne-prone skin. It supports a smooth, clear look by keeping shine under control without clogging pores.
Journal of Cosmetic Dermatology, 2022International Journal of Toxicology, 2006
Where does this cleanser go in a skincare routine for acne-prone skin?
This enzyme powder cleanser is used once a week in your weekly routine step. It helps remove impurities and excess oil while keeping your skin calm and smooth.
Can I use this cleanser with retinol, and in what order?
You can use this enzyme powder cleanser alongside retinol, but since both can be active on your skin, it is best to use them on separate days or times to prevent irritation. Using this cleanser on your weekly routine day and your retinol on other nights helps keep your skin smooth while managing oiliness safely.
How often should I use this cleanser?
This enzyme powder cleanser is a great fit for your acne-prone skin and is used once a week in the Lovi routine. People who tolerate this type of gentle exfoliation well and see good results can carefully use it more often.
Can this cleanser clog pores, cause breakouts or purging for acne-prone skin?
This cleanser is a great fit for acne-prone skin because gentle cleansers like sodium lauroyl glutamate and sodium cocoyl isethionate effectively remove excess oil and impurities from pores without disrupting the skin barrier. Papain and bromelain provide light exfoliation that helps manage oiliness, while soothing ingredients like allantoin and vitamin E minimize irritation and keep skin calm. It is unlikely to clog pores or cause breakouts.
Is this cleanser fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A fixed combination of hydroxypinacolone retinoate, retinol glycospheres, and papain glycospheres in aqueous gel applied once daily for 12 weeks achieved a 41% mean reduction in GAGS score and a 40.8% mean reduction in total lesions, with 15.3% of patients experiencing mild to moderate local side effects, in 94 evaluable patients with comedonal-papular, mild to moderate acne of the face.
Giornale Italiano Di Dermatologia E Venereologia, 2015Sodium cocoyl isethionate micelles are too large to penetrate stratum corneum aqueous pores, resulting in significant steric hindrance that prevents skin barrier perturbation and explains its skin mildness.
Journal of Cosmetic Science, 2007Topical application of (-)-epigallocatechin-3-gallate (EGCG) to human skin before UV irradiation decreases UV-induced production of hydrogen peroxide by 68-90% and nitric oxide by 30-100%, inhibits leukocyte infiltration and lipid peroxidation by 41-84%, and restores glutathione levels and glutathione peroxidase activity compared to UV exposure alone.
Carcinogenesis, 2001Application of green tea extracts on normal human skin resulted in dose-dependent inhibition of UV-evoked erythema, reduced sunburn cells, protected Langerhans cells, and decreased UV-induced DNA damage compared to untreated UV-exposed skin.
Journal of the American Academy of Dermatology, 2001Topical papain treatment may slightly decrease pain within 30 minutes in humans stung by Chrysaora chinensis compared to placebo.
Wilderness & Environmental Medicine, 2016Reflux extraction of Carica papaya leaves yielded higher antioxidant capacity and superior in vitro wound-healing activities including fibroblast proliferation, cell migration, and collagen synthesis in human skin fibroblasts compared to ultrasonic-assisted extraction and agitation.
Molecules, 2020Carica papaya leaf extracts obtained via supercritical fluid and conventional methods demonstrated antioxidant and cytoprotective effects on skin fibroblasts against oxidative stress, driven by their respective lipophilic and hydrophilic constituents.
Molecules, 2021Daily application of a cream containing niosomes loaded with purple glutinous rice extract in 20 human volunteers for 28 days resulted in a significant decrease in melanin index and skin roughness by -14.05% and -9.95%, and increases in skin hydration and elastic recovery by +48.73% and +35.98% compared to initial values.
International Journal of Cosmetic Science, 2020The iontophoretic delivery of hyaluronic acid nanogel-loaded Saccharomyces/Rice Ferment Filtrate significantly reduced advanced glycation end products and mitigated skin stiffening in an ex vivo skin tissue glycation model.
International Journal of Nanomedicine, 2025Red rice extract suppressed UVB-induced inflammation and skin aging in human skin fibroblasts by inhibiting the MAPK signaling pathway, leading to decreased NF-kappa B and AP-1 activation, reduced ECM degradation, and increased ECM synthesis compared to UVB-irradiated controls.
Natural Product Communications, 2016Oral sodium bicarbonate improved Yo-Yo IR2 distance by 21% and repeated sprint completion time by 1.9%, while topical sodium bicarbonate improved repeated sprint time by 2.0% without affecting Yo-Yo IR2 distance, in recreationally trained male athletes compared to placebo.
Journal of the International Society of Sports Nutrition, 2023Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction.
Journal of Clinical and Diagnostic Research, 2017Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo.
Experimental Dermatology, 2009An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne.
Clinical, Cosmetic and Investigational Dermatology, 2019Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers.
Experimental Dermatology, 2003Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation.
Journal of Periodontology, 2009Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream.
Journal of Cosmetic Dermatology, 2022
Ingredients
Sodium Lauroyl Glutamate, Sodium Cocoyl Isethionate, Papain, Bromelain, Sodium Bicarbonate, Silica, Allantoin, Tocopherol Vitamin E, Ascorbic Acid, Water
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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