# Good Molecules Niacinamide Serum for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/nl/p/good-molecules/niacinamide-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Good Molecules](https://lovi.care/skincare/nl/brands/good-molecules)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Suitable for normal skin, this serum utilizes niacinamide and glycerin to provide antioxidant, anti-inflammatory, and humectant actions, which are beneficial for general skin health and hydration.
- While it offers good pore-cleansing and texture improvement, it lacks specialized ingredients to directly target your redness and irritation.
- The formulation is safe for your sensitive skin, as it avoids harsh or prohibited ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/good-molecules/niacinamide-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/nl/p/good-molecules/niacinamide-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/nl/p/good-molecules/niacinamide-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/nl/p/good-molecules/niacinamide-serum/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/nl/p/good-molecules/niacinamide-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/nl/p/good-molecules/niacinamide-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/nl/p/good-molecules/niacinamide-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/good-molecules/niacinamide-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/good-molecules/niacinamide-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Glycerin, Dipropylene Glycol, Betaine, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% niacinamide significantly decreased sebum excretion rate in Japanese individuals and casual sebum levels in Caucasian individuals compared to placebo or baseline. ([Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical dry mouth products containing olive oil, betaine, and xylitol significantly increased unstimulated whole salivary flow rates, reduced xerostomia complaints, and improved quality of life in adults with polypharmacy-induced xerostomia compared to their normal routine care, with no clinically significant adverse events. ([Journal of Oral Rehabilitation, 2007](https://pubmed.ncbi.nlm.nih.gov/17824884/))
- Soaps containing betaine caused the least skin irritation compared to other tested soaps in twenty-eight healthy subjects, though irritation did not decrease with increasing concentrations of betaine. ([Skin Research and Technology, 2003](https://pubmed.ncbi.nlm.nih.gov/12535284/))
- A combination of Aloe barbadensis leaf extract and trimethylglycine in a 1:1 mass ratio synergistically increased aquaporin 3 expression by up to 380% in keratinocytes and safely improved skin hydration in healthy volunteers. ([Molecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38611819/))

## Why other serums fit sensitive skin better

- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))

## What reviewers say

Based on a very large amount of data, this serum is highly regarded for its lightweight, non-sticky feel and its effectiveness in visibly reducing pores and smoothing skin texture, all at an accessible price. Many users found it beneficial for controlling oil and redness. A smaller number of users reported experiencing breakouts or irritation, indicating it might not be suitable for all sensitive skin types.

- Liked: Affordable price (mostly mentioned)
- Liked: Improves texture (often mentioned)
- Liked: Minimizes pores (often mentioned)
- Liked: Controls oil/redness (sometimes noted)
- Liked: Elegant texture (sometimes noted)
- Disliked: Caused breakouts (sometimes noted)
- Disliked: No visible results (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Skin irritation (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Good Molecules Niacinamide Serum work for sensitive skin?

Good Molecules Niacinamide Serum works reasonably well for sensitive skin because it avoids harsh ingredients and uses glycerin to help keep skin hydrated, though it lacks specialized ingredients to calm redness. A treatment of this type needs soothing ingredients and calming plant extracts to properly target sensitive skin concerns.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for sensitive skin?

This serum works for your sensitive skin because it contains niacinamide and glycerin, which calm and hydrate without causing irritation. For this skin, a treatment needs soothing ingredients to actively target redness and irritation while keeping hydration balanced.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for sensitive skin?

Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
Sources: [Cutis, 2005](https://pubmed.ncbi.nlm.nih.gov/16209160/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Glycerin do for sensitive skin?

Glycerin helps keep sensitive skin soft and deeply hydrated while supporting the skin barrier. It is unlikely to cause irritation and may protect against dryness and roughness.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Acta Dermato-venereologica, 1999](https://pubmed.ncbi.nlm.nih.gov/10598752/)

### Where does it go in a skincare routine for sensitive skin?

This treatment is applied in the evening after your cleanser and soothing toner, followed by a moisturizer. It is unlikely to irritate your sensitive skin, but a product for this skin also needs soothing ingredients to calm redness.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first and following it with your retinol product. This helps keep your skin hydrated while you use retinol, though sensitive skin needs a product that also specifically targets redness and irritation.

### How often should I use it?

You can safely use this serum in your evening routine, as it has a gentle formula that avoids harsh ingredients. To properly care for sensitive skin, a product of this type needs calming ingredients and extra soothing agents to actively reduce redness and irritation.

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to cause breakouts for sensitive skin, though some reviewers mention this issue. A product for this skin needs soothing ingredients like centella asiatica or green tea to calm redness while keeping pores clear.

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/nl/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — €160.00 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — €35.50 at Amazon
- [COSRX The Vitamin C 23 Serum](https://lovi.care/skincare/nl/p/cosrx/the-vitamin-c-23-serum/for/sensitive-skin) — High fit — €19.00 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — €21.95 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/nl/p/skin1004/centella-asiatica-toning-toner/for/sensitive-skin) — Superior fit — €17.96 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/nl/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — €19.79 at Amazon

## Where to buy

- Amazon.nl: €17.96 (https://www.amazon.nl/dp/B08R994Q1L?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Niacinamide, Dipropylene Glycol, Glycerin, 1,2-Hexanediol, Betaine, Hydroxyethyl Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Xanthan Gum, Ethylhexylglycerin, Polysorbate 60, Sorbitan Isostearate, Diphenyl Dimethicone, Disodium Edta, Triethylhexanoin, Polyglyceryl-10 Oleate, Hydrogenated Lecithin, Phenoxyethanol, Chlorphenesin, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/good-molecules/niacinamide-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/good-molecules/niacinamide-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/good-molecules/niacinamide-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/good-molecules/niacinamide-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/good-molecules/niacinamide-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/good-molecules/niacinamide-serum/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/good-molecules/niacinamide-serum/for/sensitive-skin (this page)
- Spain: https://lovi.care/skincare/es/p/good-molecules/niacinamide-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/good-molecules/niacinamide-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/good-molecules/niacinamide-serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/good-molecules/niacinamide-serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/good-molecules/niacinamide-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/good-molecules/niacinamide-serum/for/sensitive-skin