# Farmacy 10% Niacinamide Night Mask for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/nl/p/farmacy/10-niacinamide-night-mask/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Farmacy](https://lovi.care/skincare/nl/brands/farmacy)
Category: [Face masks](https://lovi.care/skincare/nl/best/face-masks)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other nourishing masks fit it better.

## Why this fit

- Suitable for normal skin, this product offers excellent nourishing and barrier-enhancing effects due to niacinamide and beta-glucan, which improve skin resilience. Panthenol and allantoin provide hydration and soothing benefits that are supportive for your wrinkles and fine lines.
- The formulation is highly compatible with normal skin due to the antioxidant activity of niacinamide and humectant action of panthenol.
- The safety profile is excellent, with no risks of irritation for your normal skin due to the absence of prohibited or harsh ingredients and the presence of soothing ingredients like niacinamide and bisabolol.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/farmacy/10-niacinamide-night-mask/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/nl/p/farmacy/10-niacinamide-night-mask/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/nl/p/farmacy/10-niacinamide-night-mask/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/nl/p/farmacy/10-niacinamide-night-mask/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/nl/p/farmacy/10-niacinamide-night-mask/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/nl/p/farmacy/10-niacinamide-night-mask/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/nl/p/farmacy/10-niacinamide-night-mask/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/farmacy/10-niacinamide-night-mask/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/farmacy/10-niacinamide-night-mask/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Panthenol Vitamin B5, Upcycled Blueberry Seed Oil, Beta-Glucan, Shea Butter

## What the research says

- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups. ([Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37171578/))
- Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment. ([The Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35570397/))
- Topical application of oat beta-glucan ameliorates epidermal hyperplasia and accelerates epidermal barrier recovery by promoting keratinocyte differentiation through dectin-1-mediated ERK and p38 signaling pathways that upregulate CaSR expression. ([International Journal of Biological Macromolecules, 2021](https://pubmed.ncbi.nlm.nih.gov/34237364/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))

## Why other nourishing masks fit mature skin better

- Caviar oil enhanced adipocyte differentiation in vitro, reduced MMP expression while increasing collagen and elastin formation ex vivo, and improved skin moisture, elasticity, and density in 102 participants over four weeks of Cavi Balm usage compared to baseline. ([In Vivo, 2023](https://pubmed.ncbi.nlm.nih.gov/37652485/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))

## What reviewers say

Based on a very large amount of data, this product is highly praised for improving skin texture, refining pores, and providing deep hydration. It is generally well-tolerated by various skin types, though some users find it expensive or potentially irritating for highly reactive skin.

- Liked: Improves texture (mostly mentioned)
- Liked: Deeply hydrating (often mentioned)
- Liked: Refines pores (often mentioned)
- Liked: Non-sticky texture (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Causes irritation (rarely noted)
- Disliked: Comedogenic ingredients (rarely noted)
- Disliked: Inconvenient packaging (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using the creamy mask 3x a week and build up to daily use if your skin tolerates it.
- Apply the creamy mask after cleansing and toning , but always before your favorite moisturizer.
- Smooth an even layer of the creamy mask over your skin, avoiding any unnecessary rubbing.
- For the best results , apply the creamy mask directly onto clean and dry skin.
- Always do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/1bd8a450c8dc72304ff10d2ee9cf85f9.mp4

## Questions and answers

### How well does Farmacy 10% Niacinamide Night Mask work for mature skin?

This mask works reasonably well for mature skin, helping to keep it calm and hydrated with niacinamide and panthenol. Mature skin needs a nourishing mask with powerful firming peptides and rich antioxidants to smooth fine lines and deeply support aging skin.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### Which ingredients make this mask a good fit for mature skin?

This mask works for mature skin thanks to niacinamide and beta-glucan, which help strengthen the skin and improve resilience. Panthenol and allantoin also provide soothing hydration that is supportive for fine lines. Mature skin generally needs formulas packed with targeted anti-wrinkle actives, deep moisturizers, and firming peptides to effectively smooth lines and restore elasticity.
Sources: [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### What does Niacinamide do for mature skin?

Niacinamide helps mature skin by smoothing out fine lines and wrinkles, reducing dark spots, and improving overall skin elasticity. It is also very well tolerated and supports a strong skin barrier to keep skin looking healthy.
Sources: [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Panthenol do for mature skin?

Panthenol helps mature skin by boosting hydration, smoothing dryness, and supporting the skin barrier to keep it soft and comfortable. It is unlikely to cause irritation and may help reduce the look of fine lines by improving overall moisture levels.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29577586/)

### Where does this mask go in a skincare routine for mature skin?

This nourishing mask goes into your weekly evening routine, after cleansing and an enzyme powder, and before your treatment and moisturizer. Mature skin also needs targeted anti-aging ingredients like peptides, retinoids, or potent antioxidants to firm and smooth fine lines.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/), [Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/)

### Can I use this mask with retinol, and in what order?

You can use this mask in your evening routine along with retinol, applying it after your retinol treatment to help soothe and hydrate your skin. This type of product needs rich nourishing ingredients like ceramides, peptides, and botanical oils to better support firmness and elasticity in mature skin.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/)

### How often should I use this mask?

This mask works well as a weekly step in your routine for mature skin. A product of this type for your skin needs nourishing and barrier-enhancing ingredients like niacinamide and beta-glucan, along with panthenol and shea butter to help smooth fine lines and keep the skin soft.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26151786/)

### Can this mask clog pores, cause breakouts or purging for mature skin?

This mask is unlikely to clog pores or cause breakouts for mature skin, as it contains no harsh ingredients and features soothing components that help keep skin calm. Mature skin often needs richer, deeply nourishing ingredients like shea butter and protective oils to stay soft and smooth.

### Is this mask fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for mature skin

- [La Prairie Skin Caviar Luxe Sleep Mask](https://lovi.care/skincare/nl/p/la-prairie/skin-caviar-luxe-sleep-mask/for/mature-skin) — High fit — €22.74 at Amazon
- [Allies of Skin 1A Retinal + Peptides Overnight Mask](https://lovi.care/skincare/nl/p/allies-of-skin/1a-retinal-and-peptides-overnight-mask/for/mature-skin) — High fit — €98.00 at Amazon
- [Saturday Skin Yuzu Vitamin C Sleep Mask](https://lovi.care/skincare/nl/p/saturday-skin/yuzu-vitamin-c-sleep-mask/for/mature-skin) — High fit — €87.92 at Amazon

## Pairs well with

- Cleanser: [d'Alba White Truffle Return Oil Cream Cleanser](https://lovi.care/skincare/nl/p/d-alba/white-truffle-return-oil-cream-cleanser/for/mature-skin) — Superior fit — €25.07 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/mature-skin) — Superior fit — €19.90 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/nl/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — €48.84 at Amazon

## Where to buy

No store in Netherlands has a checked price for this product, so the page shows none.

## Ingredients

Water, Propanediol, Niacinamide, C15-19 Alkane, Caprylic Capric Triglyceride, Glycerin, Panthenol, 1,2-Hexanediol, Cetearyl Olivate, Cetearyl Alcohol, Sorbitan Olivate, Butyrospermum Parkii Butter Shea Butter, Betaine, Blueberry Seed Oil, Tocopheryl Acetate, Beta-Glucan, Bisabolol, Allantoin, Melia Azadirachta Flower Extract, Glycogen, Coccinia Indica Fruit Extract, Lactobacillus Ferment, Corallina Officinalis Extract, Solanum Melongena Fruit Extract, Aloe Barbadensis Flower Extract, Jojoba Seed Oil, Zingiber Officinale Root Extract, Curcuma Longa Root Extract, Ocimum Basilicum Leaf Extract Flower, Ocimum Sanctum Leaf Extract, Maltodextrin, Arginine, Carbomer, Pentylene Glycol, Sodium Phytate, Melia Azadirachta Leaf Extract, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/farmacy/10-niacinamide-night-mask/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/farmacy/10-niacinamide-night-mask/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/farmacy/10-niacinamide-night-mask/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/farmacy/10-niacinamide-night-mask/for/mature-skin
- France: https://lovi.care/skincare/fr/p/farmacy/10-niacinamide-night-mask/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/farmacy/10-niacinamide-night-mask/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/farmacy/10-niacinamide-night-mask/for/mature-skin (this page)
- Spain: https://lovi.care/skincare/es/p/farmacy/10-niacinamide-night-mask/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/farmacy/10-niacinamide-night-mask/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/farmacy/10-niacinamide-night-mask/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/farmacy/10-niacinamide-night-mask/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/farmacy/10-niacinamide-night-mask/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/farmacy/10-niacinamide-night-mask/for/mature-skin