Dr. Lili Fan Probiotic Age Defying Eye Serum for oily acne-prone skin
Sodium Hyaluronate
Myristoyl Pentapeptide-17
Palmitoyl Tetrapeptide-7
Lactobacillus Ulkenia Extract Ferment Filtrate
Bifida Lysate Ferment
Average
- HighOily Skin Fit
- AverageEffectiveness
- HighSafety
Works for oily acne-prone skin; other eye cares fit it better.
This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- This serum offers moderate benefits for your oily skin, with Lactobacillus Ulkenia Extract Ferment Filtrate and Bifida Lysate Ferment helping to balance the skin's microbiome and reduce inflammation. Myristoyl Pentapeptide-17 and Palmitoyl Tetrapeptide-7 provide excellent plumping and firming for the delicate eye area, though the formula lacks targeted ingredients for your primary concerns of acne and oiliness.
- While the product is safe for your oily skin and free from harsh ingredients, its primary function is for anti-aging and plumping, offering only supportive hydration for your specific skin issues.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of prohibited or harsh ingredients.
Questions and answers
How well does Dr. Lili Fan Probiotic Age Defying Eye Serum work for oily acne-prone skin?
This eye serum works moderately well for oily acne-prone skin, offering safe hydration and anti-aging benefits without clogging pores or causing irritation. However, because it lacks oil-controlling and acne-fighting ingredients, an eye care product for this skin type needs targeted blemish-fighting ingredients and oil-balancing agents.
Journal of Cosmetic Dermatology, 2023Dermatologic Therapy, 2022
Which ingredients make this serum a good fit for oily acne-prone skin?
This eye serum works for your oily acne-prone skin because Lactobacillus Ulkenia Extract Ferment Filtrate and Bifida Lysate Ferment help balance your skin and reduce inflammation without causing breakouts. To be a better fit for this skin type, a product of this type needs acne-fighting and oil-controlling ingredients like niacinamide and tranexamic acid.
What does Hyaluronic Acid do for oily acne-prone skin?
Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.
The Journal of Investigative Dermatology, 2017Journal of Cosmetic Dermatology, 2022
What does Myristoyl Pentapeptide-17 do for oily acne-prone skin?
Myristoyl Pentapeptide-17 is not typically used to treat oily or acne-prone skin, as it is primarily known for conditioning and supporting lash and brow growth. Oily, acne-prone skin needs products with ingredients like ceramides, niacinamide, or soothing plant extracts that help clear blemishes, balance oil, and calm redness without clogging pores.
Where does it go in a skincare routine for oily acne-prone skin?
This eye serum goes in your routine after cleansing and toning, and before moisturizing, and it may be used both morning and night. Because it focuses mainly on firming and soothing the eye area rather than clearing breakouts or reducing oil, oily acne-prone skin also needs products with ingredients like salicylic acid, niacinamide, or benzoyl peroxide to target blemishes.
Journal of Cosmetic Dermatology, 2023International Journal of Cosmetic Science, 2026
Can I use this serum with retinol, and in what order?
You can use this serum with retinol, applying the serum first to give your delicate eye area plumping and firming support while keeping your skin calm. The formula is safe and unlikely to cause irritation for your oily skin, though an oily skin type needs products with targeted acne-fighting ingredients and oil-balancing agents to fully address breakouts.
Journal of Cosmetic Dermatology, 2015Journal of Cosmetic Dermatology, 2023
How often should I use it?
You can use this eye serum daily to firm and plump the delicate eye area. Oily acne-prone skin needs a product of this type that also includes targeted ingredients to help control oil and clear breakouts.
Journal of Cosmetic Dermatology, 2015Journal of Cosmetic Dermatology, 2023
Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?
This serum is unlikely to clog pores or cause breakouts for oily acne-prone skin, as it is free from harsh ingredients and has a very safe formula. However, because it focuses on anti-aging rather than targeting breakouts, this skin type needs acne-fighting ingredients like salicylic acid and oil-balancing agents to properly manage oil and blemishes.
Is it fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.
Journal of Cosmetic Dermatology, 2015Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro.
Journal of Cosmetic Dermatology, 2023Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components.
International Journal of Cosmetic Science, 2026Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone.
Dermatologic Therapy, 2022Optimized transfersomes loaded with epigallocatechin-3-gallate and hyaluronic acid increased cell viability while reducing lipid peroxidation, intracellular ROS, and MMP expression in HaCaT cells, and exhibited higher skin permeation and deposition compared to plain EGCG.
Drug Delivery, 2017Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019
Why other eye cares fit oily acne-prone skin better
Topical combination of 5% sodium ascorbyl phosphate and 0.2% retinol reduced inflammatory acne lesions by 29.28% at 4 weeks and 63.10% at 8 weeks, outperforming either agent alone.
International Journal of Cosmetic Science, 2009Sodium ascorbyl phosphate provides effective antimicrobial action, prevents sebum oxidation, and demonstrates superior clinical efficacy compared to a standard acne treatment in patients with acne vulgaris.
International Journal of Cosmetic Science, 2005
Ingredients
Water, Sodium Hyaluronate, Menthyl Lactate, Asiatic Acid, Pentylene Glycol, Panthenol, Steareth-20, Glycerin, Lysolecithin, N-Hydroxysuccinimide, Hydroxyethylcellulose, Chrysin, Myristoyl Pentapeptide-17, Cocoyl-Oligopeptide, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Rice Protein, Lactobacillus Ulkenia Extract Ferment Filtrate, Bifida Lysate Ferment, Phenoxyethanol, Caprylyl Glycol
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-
Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-
Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-
Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-
Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-
Medical Board
Cosmetic chemist, SCS, IFSCC member
-
Medical Board, Medical Advisor
Dermatology MD
-
Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-
Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.