# Differin Gel for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/nl/p/differin/gel/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Differin](https://lovi.care/skincare/nl/brands/differin)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for oily shine and acne due to the presence of adapalene retinoid, which targets acne and oil production, making it suitable for your oily skin.
- Propylene glycol and water provide hydration and a soothing effect, helping to maintain skin comfort.
- The product is safe for your oily skin, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/differin/gel/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/nl/p/differin/gel/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/nl/p/differin/gel/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/nl/p/differin/gel/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/nl/p/differin/gel/for/acne-prone-skin): Low
- [Skin with dark spots](https://lovi.care/skincare/nl/p/differin/gel/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/nl/p/differin/gel/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/differin/gel/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/differin/gel/for/oily-acne-prone-skin): High

## Key ingredients

Adapalene, Carbomer 940, Methylparaben, Poloxamer 182, Edetate Disodium

## What the research says

- Tea tree oil nanoemulsion containing adapalene gel demonstrated significantly greater reductions in total, inflammatory, and non-inflammatory acne lesions as well as acne severity index compared to adapalene marketed gel in 100 patients with acne vulgaris over 12 weeks. ([Archives of Dermatological Research, 2022](https://pubmed.ncbi.nlm.nih.gov/34251536/))
- Daily application of adapalene 0.3%/benzoyl peroxide 2.5% gel reduced and prevented atrophic acne scar formation, achieving a total scar count change of -15.5% versus +14.4% for vehicle over 24 weeks in 67 subjects with moderate or severe facial acne. ([American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/))
- Once-daily fixed-dose clindamycin phosphate 1.2%/benzoyl peroxide 3.1%/adapalene 0.15% gel achieved superior treatment success (52.5%) and greater reductions in inflammatory and noninflammatory lesions compared to vehicle (8.1%) and dyad component gels in participants with moderate-to-severe acne over 12 weeks. ([American Journal of Clinical Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34674160/))
- Pranoprofen-loaded nanostructured lipid carriers dispersed in Carbomer 940 and Sepigel 305 gels provided sustained drug release and demonstrated anti-inflammatory efficacy in animal models without causing skin irritation or altering biophysical properties in humans. ([Gels, 2023](https://pubmed.ncbi.nlm.nih.gov/37367119/))
- Topical clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel achieved significantly greater treatment success and lesion reductions compared to vehicle in participants with moderate-to-severe acne. ([Journal of the American Academy of Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37656094/))
- Treatment with adapalene 0.3%/benzoyl peroxide 2.5% gel for 48 weeks reduced atrophic acne scar counts by 26.9% in subjects with moderate or severe facial acne, while delayed treatment starting at week 24 resulted in a smaller final reduction. ([American Journal of Clinical Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31209851/))
- Adapalene 0.3 %/benzoyl peroxide 2.5 % gel applied once daily for 12 weeks achieved a superior success rate of 33.7% compared to 11.0% for vehicle in subjects with moderate and severe inflammatory acne. ([American Journal of Clinical Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/26945741/))
- Topical chloramphenicol-betamethasone combined with sodium hyaluronate/trehalose/carbomer gel compared to chloramphenicol-betamethasone alone reduced most subjective symptoms at 1 week but increased blurred vision at 4 weeks following strabismus surgery in 31 patients, with no significant differences in conjunctival inflammation between treatments. ([Journal of Ocular Pharmacology and Therapeutics, 2019](https://pubmed.ncbi.nlm.nih.gov/31298607/))
- Incorporating nanoemulsions into hydrogels with increasing Carbopol 934 proportions from 1% to 3% progressively decreased the percutaneous flux rates of terbinafine and citral, increased drug accumulation in the stratum corneum while decreasing it in the epidermis/dermis compared to nanoemulsions alone, and shifted delivery routes from skin appendages to intercellular paths. ([International Journal of Nanomedicine, 2016](https://pubmed.ncbi.nlm.nih.gov/27877042/))
- Topical liquiritin carbomer gel treatment restored skin barrier function, increased barrier proteins and antioxidant enzymes, and decreased inflammatory cytokines and oxidative stress in a mouse model of glucocorticoid-induced skin inflammation. ([Pharmaceutics, 2024](https://pubmed.ncbi.nlm.nih.gov/39204346/))

## What reviewers say

Based on a very large amount of data, users with acne-prone, oily, and aging skin find this product effective for clearing breakouts and improving skin texture. While many users experience an initial worsening of acne and dryness, consistent use leads to significant improvements in cystic acne, skin smoothness, and hyperpigmentation. It is frequently noted as a cost-effective alternative to prescription treatments for hormonal acne and maskne, especially when combined with a gentle moisturizing routine.

- Liked: Clears stubborn acne (mostly mentioned)
- Disliked: Initial breakout (mostly mentioned)
- Liked: Accessible and affordable (often mentioned)
- Liked: Improves skin texture (often mentioned)
- Disliked: Dryness and peeling (often mentioned)
- Liked: Anti-aging benefits (sometimes noted)
- Disliked: Irritation and sensitivity (sometimes noted)
- Disliked: Slow results (sometimes noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Differin Gel work for oily skin?

Differin Differin Gel works reasonably well for oily skin by offering moderate benefits for oily shine and acne, though other products fit this skin better. An ideal product for oily skin of this type needs ingredients like niacinamide, ferulic acid, and zinc PCA to control excess oil and pores, along with ceramides and panthenol for hydration.
Sources: [Archives of Dermatological Research, 2022](https://pubmed.ncbi.nlm.nih.gov/34251536/), [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/)

### Which ingredients make this treatment a good fit for oily skin?

Adapalene makes this treatment a good fit for oily skin because it targets acne and oil production, while propylene glycol and water provide hydration and keep the skin calm and comfortable. To fit oily skin even better, this type of product needs ingredients like niacinamide and ferulic acid to control excess oil and pores, along with soothing and barrier-supporting components like zinc PCA, ceramide NP, and panthenol.
Sources: [Archives of Dermatological Research, 2022](https://pubmed.ncbi.nlm.nih.gov/34251536/), [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/)

### What does Adapalene do for oily skin?

Adapalene helps keep pores clear and calm for oily skin by targeting microcomedones and reducing inflammation. It serves as a core treatment for acne, though a product of this type for oily skin also needs ingredients that support barrier restoration to reduce potential dryness.
Sources: [Dermatology and Therapy, 2017](https://pubmed.ncbi.nlm.nih.gov/28585191/)

### What does Carbomer do for oily skin?

Carbomer helps create lightweight gel formulas that feel comfortable on oily skin without clogging pores or causing irritation. It allows products to spread smoothly while maintaining a safe, gentle profile for daily use.
Sources: [Gels, 2023](https://pubmed.ncbi.nlm.nih.gov/37367119/), [Gels, 2024](https://pubmed.ncbi.nlm.nih.gov/39057500/)

### Where does this treatment go in a skincare routine for oily skin?

This treatment goes in the evening routine after cleansing and before moisturizing, and it can also be used once a week in weekly routines. It helps manage oily shine and acne while keeping skin comfortable, though oily skin often does better with products that offer stronger oil-balancing and blemish-clearing benefits.

### Can I use this treatment with benzoyl peroxide, and in what order?

You can use this treatment alongside benzoyl peroxide, but apply them in separate steps or at different times of day to help keep your skin calm and comfortable.
Sources: [American Family Physician, 2012](https://pubmed.ncbi.nlm.nih.gov/23062156/)

### How often should I use this treatment?

You can use this treatment in the evening as part of your routine. Oily skin needs a product with retinoids to target oil production and acne, alongside soothing ingredients to maintain skin comfort.
Sources: [Archives of Dermatological Research, 2022](https://pubmed.ncbi.nlm.nih.gov/34251536/), [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/)

### Can this treatment clog pores, cause breakouts or purging for oily skin?

This treatment is likely to cause an initial breakout and peeling on oily skin because it contains adapalene, which speeds up skin renewal to clear out pores. To best care for oily skin, a treatment of this type needs ingredients that target oil production and acne without causing severe dryness.
Sources: [Archives of Dermatological Research, 2022](https://pubmed.ncbi.nlm.nih.gov/34251536/), [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/)

### Is this treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily skin

- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/nl/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/oily-skin) — Superior fit — €99.41 at Amazon
- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/nl/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-skin) — Superior fit — €10.20 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/oily-skin) — Superior fit — €35.80 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/nl/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — €21.00 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — €19.90 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/oily-skin) — Superior fit — €19.20 at Amazon

## Where to buy

No store in Netherlands has a checked price for this product, so the page shows none.

## Ingredients

Adapalene Retinoid, Carbomer 940, Edetate Disodium, Methylparaben, Poloxamer 182, Propylene Glycol, Water, Sodium Hydroxide, Hydrochloric Acid May Contain To Adjust Ph
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/differin/gel/for/oily-skin
- United Kingdom: https://lovi.care/skincare/uk/p/differin/gel/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/differin/gel/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/differin/gel/for/oily-skin
- France: https://lovi.care/skincare/fr/p/differin/gel/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/differin/gel/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/differin/gel/for/oily-skin (this page)
- Spain: https://lovi.care/skincare/es/p/differin/gel/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/differin/gel/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/differin/gel/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/differin/gel/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/differin/gel/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/differin/gel/for/oily-skin