# Derma E Vitamin C Intense Night Cream for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/nl/p/derma-e/vitamin-c-intense-night-cream/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Derma E](https://lovi.care/skincare/nl/brands/derma-e)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/nl/best/moisturizers)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate moisturizing and texture smoothing for your combination skin due to sodium hyaluronate and retinyl palmitate, which hydrate and refine skin. This product provides general skincare benefits but lacks specialized ingredients to effectively target your acne, blemishes, and breakouts.
- While glycerin and sodium hyaluronate offer humectant action suitable for combination skin, the formula does not provide sufficient ingredients for optimal oil control on your oilier areas.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-intense-night-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-intense-night-cream/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-intense-night-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-intense-night-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-intense-night-cream/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-intense-night-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-intense-night-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-intense-night-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-intense-night-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Ascorbic Acid, Sodium Hyaluronate, Probiotics, Aspalathus Linearis, Retinol

## What the research says

- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Ginkgo formulation increased skin moisturization by 27.88% and smoothness by 4.32% while reducing roughness by 0.4% and wrinkles by 4.63%, and significantly improved skin moisturization compared to the tea and rooibos formula. ([International Journal of Cosmetic Science, 2010](https://pubmed.ncbi.nlm.nih.gov/20412217/))
- The addition of Aspalathus linearis extracts to topical sunscreen formulas containing OMC and BMDBM increased protection factors by up to 50% and protected the filters against photodegradation under radiation doses up to 14.4 standard erythemal doses. ([Photochemical & Photobiological Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/41591727/))
- The combination of fermented and unfermented Aspalathus linearis extracts showed a synergistic photoprotective effect on Normal Human Dermal Fibroblast survival after UVB radiation, which further improved when combined with Polypodium leucotomos extract. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/40076948/))
- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))

## Why other moisturizers fit acne-prone skin better

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/))

## What reviewers say

Based on a very large amount of data, users consistently praise this cream for its ability to brighten dull complexions and fade hyperpigmentation while providing deep hydration without a greasy residue. A significant number of recent reviews highlight irritation and redness attributed to a formula change, making it potentially unsuitable for very sensitive skin.

- Liked: Brightens and evens tone (mostly mentioned)
- Liked: Excellent hydration (often mentioned)
- Liked: Pleasant scent (often mentioned)
- Liked: Good value (sometimes noted)
- Disliked: Irritation from new formula (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Thick texture (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help keep breakouts under control.
- Apply after your cleanser and toner, and make sure to use your SPF right after in the morning.
- Gently spread a small amount of moisturizer over your face using soft motions. Let it absorb into the skin for a minute before getting dressed or applying makeup.
- Apply on slightly damp skin to help lock in extra moisture. This keeps your combination skin balanced without feeling heavy.
- Avoid the eye area and do a patch test before your first use. Stop using if you feel any irritation.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Derma E Vitamin C Intense Night Cream work for acne-prone skin?

Derma E Vitamin C Intense Night Cream works moderately well for acne-prone skin, offering basic hydration and smoothing without targeting breakouts directly. A product of this type needs specific blemish-fighting ingredients, oil control, and soothing extracts to truly fit acne-prone skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for acne-prone skin?

This cream works adequately for acne-prone skin because it contains sodium hyaluronate and retinyl palmitate to smooth and hydrate the surface. However, a moisturizing treatment for this skin type needs targeted blemish-fighting ingredients and oil-control agents to manage breakouts effectively.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What does Vitamin C do for acne-prone skin?

Vitamin C helps brighten skin, smooth out uneven tones, and fade dark spots left behind by breakouts. It is also packed with antioxidants that may help protect acne-prone skin from everyday environmental stress.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37128827/), [Journal of Drugs in Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/39231081/)

### What does Hyaluronic Acid do for acne-prone skin?

Hyaluronic acid helps acne-prone skin by soothing irritation, calming redness, and keeping the skin balanced without clogging pores. When combined with targeted ingredients like zinc oxide, it may also help reduce breakouts.
Sources: [Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/), [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### Where does this cream go in a skincare routine for acne-prone skin?

This moisturizing treatment goes in the evening routine after cleansing and before your final moisturizer, or it can be used alone as your nighttime moisturizer. Because this product offers only an average fit for acne-prone skin, a better choice for this skin type needs targeted oil-control ingredients and blemish-fighting actives to properly manage breakouts.

### Can I use this cream with niacinamide, and in what order?

You can use this cream with niacinamide by applying niacinamide first and following with this moisturizing treatment. This cream is safe for your skin and is unlikely to cause irritation. Acne-prone skin needs a product with oil control and specialized blemish-fighting ingredients.

### How often should I use this cream?

You can use this moisturizing treatment in the evening as part of your routine. While it offers moderate hydration, acne-prone skin needs specialized oil control and blemish-targeting ingredients to work best.

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is unlikely to cause severe irritation or breakouts for acne-prone skin, though some users report occasional clogged pores because it lacks specialized oil-controlling ingredients. An acne-prone skin routine needs ingredients like salicylic acid or niacinamide to help clear blemishes and manage excess oil.

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment on your body and around the eyes, as it has a safe and gentle formula for different areas of skin. However, because the skin around the eyes is very thin, a product used there needs ingredients like hyaluronic acid and plant extracts to hydrate and smooth fine lines without causing irritation.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol and cetearyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for acne-prone skin

- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/nl/p/belif/the-true-cream-aqua-bomb/for/acne-prone-skin) — High fit — €35.96 at Amazon
- [ANUA Heartleaf 70% Soothing Cream](https://lovi.care/skincare/nl/p/anua/heartleaf-70-soothing-cream/for/acne-prone-skin) — High fit — €25.29 at Amazon
- [Purito Centella Unscented Recovery Cream](https://lovi.care/skincare/nl/p/purito/centella-unscented-recovery-cream/for/acne-prone-skin) — High fit — €12.55 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/nl/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — €19.90 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/nl/p/d-alba/piedmont-waterfull-mild-sunscreen/for/acne-prone-skin) — Superior fit — €16.75 at Amazon

## Where to buy

No store in Netherlands has a checked price for this product, so the page shows none.

## Ingredients

Water, Caprylic Capric Triglyceride, Glycerin, Sodium Hyaluronate, Cetyl Alcohol, Ethylhexyl Palmitate, Cetearyl Alcohol, Cetearyl Glucoside, Cetyl Palmitate, Sorbitan Palmitate, Sorbitan Oleate, Diheptyl Succinate, Capryloyl Glycerin Sebacic Acid Copolymer, Pseudozyma Epicola, Prunus Armeniaca Kernel Oil Apricot Kernel Oil, Helianthus Annuus Seed Oil Sunflower Seed Oil, Prunus Amygdalus Dulcis Oil, Saururus Chinensis Extract Ferment Filtrate, Aspalathus Linearis Leaf Extract, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Rosa Canina Oil Fruit Rosehip Oil Fruit, Camellia Sinensis Leaf Extract, Olea Europaea Oil Fruit Olive Oil Fruit, Retinyl Vitamin A Palmitate, Panthenol Vitamin B5, Tocopheryl Acetate Vitamin E, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Ethylhexylglycerin, Oils
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/derma-e/vitamin-c-intense-night-cream/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/derma-e/vitamin-c-intense-night-cream/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/derma-e/vitamin-c-intense-night-cream/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/derma-e/vitamin-c-intense-night-cream/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/derma-e/vitamin-c-intense-night-cream/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/derma-e/vitamin-c-intense-night-cream/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/derma-e/vitamin-c-intense-night-cream/for/acne-prone-skin (this page)
- Spain: https://lovi.care/skincare/es/p/derma-e/vitamin-c-intense-night-cream/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/derma-e/vitamin-c-intense-night-cream/for/acne-prone-skin
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