# Derma E Vitamin C Concentrated Serum for skin with dark spots

**Lovi Fit: High fit for skin with dark spots.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/nl/p/derma-e/vitamin-c-concentrated-serum/for/dark-spots

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Derma E](https://lovi.care/skincare/nl/brands/derma-e)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with dark spots: hyperpigmentation, sun spots, and uneven skin tone. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for skin with dark spots.

## Why this fit

- This serum offers excellent brightening and evening of skin tone for your normal skin, as Tocopheryl Acetate and Rosa Canina Seed Oil provide antioxidant protection and improve skin tone. Glycerin and Sodium Hyaluronate further enhance hydration, making it highly suitable for your skin type.
- The formula is safe for your normal skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
- It addresses your pigmentation concerns effectively due to the presence of Vitamin C and Vitamin E in concentrations that provide antioxidant and brightening effects.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-concentrated-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-concentrated-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-concentrated-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-concentrated-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-concentrated-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-concentrated-serum/for/dark-spots): High (this page)
- [Mature skin](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-concentrated-serum/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-concentrated-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/derma-e/vitamin-c-concentrated-serum/for/oily-acne-prone-skin): High

## Key ingredients

Ascorbic Acid, Sodium Hyaluronate, Probiotics, Camellia Sinensis Extract, Rosehip Seed Oil

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction. ([Journal of Clinical and Diagnostic Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28384900/))
- Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/))
- An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/))
- Topical treatments containing rosehip extract may reduce the size and erythema of postsurgical scars through macrophage polarization and inflammatory cytokine inhibition, though current clinical evidence remains insufficient to recommend its routine use. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/37605366/))
- Sunflower and rosehip oil nanoemulsions prepared with a mix of phospholipids and synthetic emulsifiers permeated intact skin to the dermis and showed a more prominent healing effect in a human organotypic skin explant culture wound model compared to nanoemulsions prepared only with phospholipids. ([Pharmaceutics, 2023](https://pubmed.ncbi.nlm.nih.gov/36986857/))
- A nanoemulsion containing 1 mg/mL kojic dipalmitate and 5% rosehip oil demonstrated high incorporation efficiency, suitable physicochemical stability, antioxidant and depigmenting efficacy close to 1 mM ascorbic acid, and no cytotoxicity at concentrations from 0.06% to 1% in vitro. ([Pharmaceutics, 2023](https://pubmed.ncbi.nlm.nih.gov/36839792/))

## What reviewers say

Based on a very large amount of data, users frequently praise this serum for its ability to brighten dull complexions and provide lightweight hydration without irritating sensitive skin. A minority of users report no visible changes in hyperpigmentation or fine lines, and some experience a tacky residue or breakouts.

- Liked: Brightens skin tone (mostly mentioned)
- Liked: Gentle for sensitive skin (often mentioned)
- Liked: Lightweight and absorbs (often mentioned)
- Liked: Hydrating and softening (sometimes noted)
- Liked: Pleasant scent (sometimes noted)
- Disliked: No visible results (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Scent dislike (rarely noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Apply this serum as part of your PM routine starting 3x/week and build up to daily use if your skin likes it.
- Place the serum after cleansing and toning, but before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute for it to absorb.
- Apply the serum on dry skin to help fade pigmentation effectively.
- Avoid the eye area and always use SPF 30+ during the day.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Derma E Vitamin C Concentrated Serum a great fit for skin with dark spots?

Derma E Vitamin C Concentrated Serum is a great fit for skin with dark spots because it contains vitamin C and vitamin E, which brighten skin tone and fade dark spots. Additionally, ingredients like glycerin and sodium hyaluronate keep your skin hydrated, while the formula's gentle profile avoids harsh irritants.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### Which ingredients make this serum a good fit for skin with dark spots?

Ascorbic acid and tocopheryl acetate make this serum a great fit because they brighten dark spots and provide antioxidant protection. Rosa canina seed oil, glycerin, and sodium hyaluronate further help by improving skin tone and keeping your skin hydrated.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Vitamin C do for skin with dark spots?

Vitamin C helps fade dark spots and brightens uneven skin. It works by slowing down pigment production and boosting overall skin clarity.
Sources: [Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029672/)

### What does Hyaluronic Acid do for skin with dark spots?

Hyaluronic acid is unlikely to directly fade dark spots, but it helps keep dry and uneven skin plump and deeply hydrated. To effectively target dark spots, this type of skin needs brightening ingredients like vitamin C or niacinamide alongside your hydrator.

### Where does it go in a skincare routine for skin with dark spots?

This treatment goes in the evening routine after cleansing and before moisturizing, which helps simplify your routine and keeps your skin safe around sun exposure. Using an antioxidant serum like this one effectively targets dark spots and helps brighten your skin over time.
Sources: [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36607762/)

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying this Vitamin C serum in the morning and your retinol at night to prevent irritation. Using them at different times of day helps your skin handle both active ingredients safely while brightening dark spots and keeping your skin smooth.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use it?

Use this treatment in the evening as part of your routine. It is a good fit for skin with dark spots, and it helps brighten your skin tone and provide antioxidant protection with a low risk of irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/), [Facial Plastic Surgery, 2014](https://pubmed.ncbi.nlm.nih.gov/24488631/)

### Can this serum clog pores, cause breakouts or purging for skin with dark spots?

This serum is unlikely to cause breakouts, as it has a very low rate of complaints for causing them and contains safe, gentle ingredients. It may help brighten dark spots while keeping your skin calm and smooth.

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for skin with dark spots

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/nl/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dark-spots) — High fit — €10.20 at Amazon
- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/nl/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/dark-spots) — High fit — €99.41 at Amazon
- [Guerlain Abeille Royale Double R Renew & Repair Serum](https://lovi.care/skincare/nl/p/guerlain/abeille-royale-double-r-renew-and-repair-advanced-serum/for/dark-spots) — High fit — €203.88 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/nl/p/cerave/foaming-facial-cleanser/for/dark-spots) — Superior fit — €21.00 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/nl/p/pyunkang-yul/calming-deep-moisture-toner/for/dark-spots) — Superior fit — €14.31 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/dark-spots) — Superior fit — €19.20 at Amazon

## Where to buy

No store in Netherlands has a checked price for this product, so the page shows none.

## Ingredients

Water, Aloe Barbadensis Leaf Juice, Glycerin, Camellia Sinensis Leaf Extract, Sodium Hyaluronate, Tocopheryl Acetate Vitamin E, Polymnia Sonchifolia Root Juice, Rosa Canina Seed Oil, Lactobacillus, Citric Acid, Alpha-Glucan Oligosaccharide, Allantoin, Panthenol Vitamin B5, Cellulose Gum, Microcrystalline Cellulose, Caprylic Capric Triglyceride, Ethylhexyl Palmitate, Xanthan Gum, Maltodextrin, Sodium Citrate, Ethylhexylglycerin, Phenoxyethanol, Oil
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/derma-e/vitamin-c-concentrated-serum/for/dark-spots
- United Kingdom: https://lovi.care/skincare/uk/p/derma-e/vitamin-c-concentrated-serum/for/dark-spots
- Ireland: https://lovi.care/skincare/ie/p/derma-e/vitamin-c-concentrated-serum/for/dark-spots
- Germany: https://lovi.care/skincare/de/p/derma-e/vitamin-c-concentrated-serum/for/dark-spots
- France: https://lovi.care/skincare/fr/p/derma-e/vitamin-c-concentrated-serum/for/dark-spots
- Italy: https://lovi.care/skincare/it/p/derma-e/vitamin-c-concentrated-serum/for/dark-spots
- Netherlands: https://lovi.care/skincare/nl/p/derma-e/vitamin-c-concentrated-serum/for/dark-spots (this page)
- Spain: https://lovi.care/skincare/es/p/derma-e/vitamin-c-concentrated-serum/for/dark-spots
- Canada: https://lovi.care/skincare/ca/p/derma-e/vitamin-c-concentrated-serum/for/dark-spots
- Australia: https://lovi.care/skincare/au/p/derma-e/vitamin-c-concentrated-serum/for/dark-spots
- Singapore: https://lovi.care/skincare/sg/p/derma-e/vitamin-c-concentrated-serum/for/dark-spots
- Saudi Arabia: https://lovi.care/skincare/sa/p/derma-e/vitamin-c-concentrated-serum/for/dark-spots
- United Arab Emirates: https://lovi.care/skincare/ae/p/derma-e/vitamin-c-concentrated-serum/for/dark-spots
