# COSRX The Niacinamide 15 Serum for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/nl/p/cosrx/the-niacinamide-15-serum/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [COSRX](https://lovi.care/skincare/nl/brands/cosrx)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your oily skin, this serum effectively addresses acne, blemishes, and oiliness with niacinamide and zinc PCA to regulate sebum and reduce inflammation.
- Allantoin further soothes the skin, complementing the primary actives for a balanced and comfortable experience.
- The formula is safe for your skin, containing no harsh ingredients and featuring beneficial components that minimize irritation risk.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/cosrx/the-niacinamide-15-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/nl/p/cosrx/the-niacinamide-15-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/nl/p/cosrx/the-niacinamide-15-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/nl/p/cosrx/the-niacinamide-15-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/nl/p/cosrx/the-niacinamide-15-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/nl/p/cosrx/the-niacinamide-15-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/nl/p/cosrx/the-niacinamide-15-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/cosrx/the-niacinamide-15-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/cosrx/the-niacinamide-15-serum/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Niacinamide, Acetyl Glucosamine, Zinc Pca, Trehalose, Allantoin

## What the research says

- Topical nicotinamide plus an antibacterial adhesive agent and zinc-pyrrolidone carboxylic acid combined with adapalene significantly reduced noninflammatory acne lesions by the second week of therapy compared to placebo with adapalene in patients with moderate acne vulgaris. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- SD-101 6% cream showed no statistically significant difference compared to vehicle in time to target wound closure or the proportion of patients achieving complete target wound closure within 3 months in patients with epidermolysis bullosa. ([Orphanet Journal of Rare Diseases, 2020](https://pubmed.ncbi.nlm.nih.gov/32576219/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide. ([Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/))
- N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers. ([Advanced Pharmaceutical Bulletin, 2016](https://pubmed.ncbi.nlm.nih.gov/28101465/))
- Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants. ([Journal of Cosmetic and Laser Therapy, 2019](https://pubmed.ncbi.nlm.nih.gov/30040516/))
- Zinc PCA inhibits UVA-induced matrix metalloproteinase-1 production through suppressed AP-1 activation and enhances type I collagen synthesis by increasing SVCT2 mRNA expression in cultured normal human dermal fibroblasts. ([International Journal of Cosmetic Science, 2012](https://pubmed.ncbi.nlm.nih.gov/21834944/))
- Sodium trehalose sulfate decreased transepidermal water loss and increased stratum corneum water content in participants with low stratum corneum water content when applied for 4 weeks compared to placebo. ([Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38606717/))
- Topical chloramphenicol-betamethasone combined with sodium hyaluronate/trehalose/carbomer gel compared to chloramphenicol-betamethasone alone reduced most subjective symptoms at 1 week but increased blurred vision at 4 weeks following strabismus surgery in 31 patients, with no significant differences in conjunctival inflammation between treatments. ([Journal of Ocular Pharmacology and Therapeutics, 2019](https://pubmed.ncbi.nlm.nih.gov/31298607/))
- Topical treatment with Thealoz Duo significantly improved dry eye disease symptoms, tear break-up time, and restored tear lipid layer functionality by reducing inflammatory response proteins in moderate to severe dry eye patients over 56 days. ([Journal of Clinical Medicine, 2025](https://pubmed.ncbi.nlm.nih.gov/40807147/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Prophylactic application of a topical scar gel containing Allium cepae extract, allantoin, and heparin significantly improves patient-assessed scar color, stiffness, and irregularity compared to no treatment in women following a cesarean section. ([Journal of Drugs in Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24509969/))

## What reviewers say

This serum is widely praised by users with oily and acne-prone skin for its ability to significantly control sebum and refine pore texture, often delivering a smoother, "glass skin" finish. The high 15% concentration is effective for many, but frequently causes irritation, stinging, or barrier damage for those with sensitive or dry skin types. This summary is based on a very large amount of data and should be definitely taken into account.

- Liked: Controls excess oil (mostly mentioned)
- Liked: Lightweight absorption (often mentioned)
- Liked: Reduces pore visibility (often mentioned)
- Liked: Smoothes skin texture (often mentioned)
- Liked: Fades acne marks (sometimes noted)
- Disliked: Causes irritation (sometimes noted)
- Disliked: Too strong (sometimes noted)
- Disliked: Drying effect (rarely noted)
- Disliked: Induces breakouts (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes COSRX The Niacinamide 15 Serum a great fit for oily acne-prone skin?

COSRX The Niacinamide 15 Serum is a great fit for your oily acne-prone skin because it uses niacinamide and zinc PCA to control excess oil and calm blemishes. Allantoin further soothes your skin for a comfortable experience, and the gentle formula helps keep the risk of irritation low.
Sources: [The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/), [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

This serum is a great fit for your oily acne-prone skin because it contains niacinamide and zinc PCA to control excess oil and calm inflammation, along with allantoin to keep your skin comfortable. These ingredients work together to help reduce blemishes while remaining gentle on your skin.
Sources: [The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/), [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### What does Niacinamide do for oily acne-prone skin?

Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/)

### What does Acetyl Glucosamine do for oily acne-prone skin?

Acetyl glucosamine helps fade dark spots and uneven areas while keeping your skin hydrated and smooth. Studies show it is safe for daily use and works especially well when paired with ingredients like niacinamide.
Sources: [Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/), [The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/19845667/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This serum goes in the evening routine after cleansing and before moisturizing, fitting well into your schedule for simplicity and safety. It helps regulate oil and reduce inflammation with niacinamide and zinc PCA while soothing the skin.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/)

### Can I use this serum with retinol, and in what order?

You can use this serum alongside a retinol, applying the treatment serum after your cleansing steps and before your moisturizer. The formula helps balance oil and soothe the skin, minimizing irritation risk when paired with active routines.
Sources: [The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/), [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### How often should I use this serum?

This serum is a great fit and is best used in the evening as part of your routine to keep oily skin balanced and calm. It contains niacinamide and zinc PCA, which help regulate oil and reduce blemishes safely and comfortably.
Sources: [The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/), [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is a great fit for your oily acne-prone skin, as niacinamide and zinc PCA help control oil and reduce blemishes while minimizing irritation. While some reviewers report breakouts or irritation because the formula may feel too strong, ingredients like allantoin help soothe your skin.
Sources: [The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32983333/), [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/nl/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-acne-prone-skin) — Superior fit — €10.20 at Amazon
- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/nl/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/oily-acne-prone-skin) — Superior fit — €99.41 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — €35.50 at Amazon

## Pairs well with

- Cleanser: [Paula's Choice CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/nl/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — €29.00 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — €36.00 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/oily-acne-prone-skin) — Superior fit — €19.20 at Amazon

## Where to buy

No store in Netherlands has a checked price for this product, so the page shows none.

## Ingredients

Water, Pentylene Glycol, Niacinamide, Butylene Glycol, Acetyl Glucosamine, 1,2-Hexanediol, Zinc Pca, Trehalose, Hydrolyzed Sclerotium Gum, Pullulan, Allantoin, Ethylhexylglycerin, Sodium Phytate, Tocopherol, Xanthan Gum, Citric Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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- United Kingdom: https://lovi.care/skincare/uk/p/cosrx/the-niacinamide-15-serum/for/oily-acne-prone-skin
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