# CLIV PHA Mild Enzyme Powder for skin with dark spots

**Lovi Fit: High fit for skin with dark spots.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/nl/p/cliv/pha-mild-enzyme-powder/for/dark-spots

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: CLIV
Category: [Exfoliants](https://lovi.care/skincare/nl/best/exfoliators)

This fit is calculated for the concerns frequently associated with dark spots: hyperpigmentation, sun spots, and uneven skin tone. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for skin with dark spots; a few products fit it even better.

## Why this fit

- Offers moderate exfoliation for your pigmentation concerns and normal skin type, as papain and bromelain provide enzymatic cleansing to support desquamation regulation.
- The inclusion of allantoin and glycerin further soothes your skin, while sodium hyaluronate and lactobacillus punica granatum extract fruit ferment offer hydration and barrier support.
- The product is safe for your normal skin due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/cliv/pha-mild-enzyme-powder/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/nl/p/cliv/pha-mild-enzyme-powder/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/nl/p/cliv/pha-mild-enzyme-powder/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/nl/p/cliv/pha-mild-enzyme-powder/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/nl/p/cliv/pha-mild-enzyme-powder/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/nl/p/cliv/pha-mild-enzyme-powder/for/dark-spots): High (this page)
- [Mature skin](https://lovi.care/skincare/nl/p/cliv/pha-mild-enzyme-powder/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/cliv/pha-mild-enzyme-powder/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/cliv/pha-mild-enzyme-powder/for/oily-acne-prone-skin): High

## Key ingredients

Papain, Bromelain, Gluconolactone, Sodium Hyaluronate, Allantoin

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- Topical papain treatment may slightly decrease pain within 30 minutes in humans stung by Chrysaora chinensis compared to placebo. ([Wilderness & Environmental Medicine, 2016](https://pubmed.ncbi.nlm.nih.gov/26827260/))
- A fixed combination of hydroxypinacolone retinoate, retinol glycospheres, and papain glycospheres in aqueous gel applied once daily for 12 weeks achieved a 41% mean reduction in GAGS score and a 40.8% mean reduction in total lesions, with 15.3% of patients experiencing mild to moderate local side effects, in 94 evaluable patients with comedonal-papular, mild to moderate acne of the face. ([Giornale Italiano Di Dermatologia E Venereologia, 2015](https://pubmed.ncbi.nlm.nih.gov/25876142/))
- Reflux extraction of Carica papaya leaves yielded higher antioxidant capacity and superior in vitro wound-healing activities including fibroblast proliferation, cell migration, and collagen synthesis in human skin fibroblasts compared to ultrasonic-assisted extraction and agitation. ([Molecules, 2020](https://pubmed.ncbi.nlm.nih.gov/31991676/))
- Oral bromelain slightly reduced pain compared to controls (mean difference -0.27) and topical bromelain reduced time to complete debridement by 6.89 days, with no major health risks reported. ([Nutrition and Health, 2023](https://pubmed.ncbi.nlm.nih.gov/37157782/))
- An upcycled pineapple leaf fibre crosspolymer forms a physical barrier that protects against environmental aggressors while providing antioxidant, anti-inflammatory, antipollution, UV protection, hydration, and hair benefits. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/41524117/))
- A coaxial electrospun core-shell nanofiber scaffold delivering bromelain and salvianolic acid B demonstrated sustained drug release, in vitro endothelial cell migration, increased capillary formation in an in ovo assay, and in vivo efficacy for skin regeneration and wound healing. ([Biomedical Materials, 2017](https://pubmed.ncbi.nlm.nih.gov/28580904/))
- Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/))
- Gluconolactone and tartaric acid significantly lower transepidermal water loss and erythema after sodium lauryl sulphate challenge compared to vehicle, untreated control, and glycolic acid in healthy subjects. ([The British Journal of Dermatology, 1997](https://pubmed.ncbi.nlm.nih.gov/9470910/))
- Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients. ([The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Prophylactic application of a topical scar gel containing Allium cepae extract, allantoin, and heparin significantly improves patient-assessed scar color, stiffness, and irregularity compared to no treatment in women following a cesarean section. ([Journal of Drugs in Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24509969/))

## What reviewers say

Based on limited data, this enzyme powder is highly praised for its ability to gently exfoliate and deeply cleanse the skin without causing irritation or dryness. Users with sensitive and mixed skin types report that it effectively removes impurities and makeup, leaving the skin feeling exceptionally smooth, soft, and hydrated.

- Liked: Non-stripping cleanse (mostly mentioned)
- Liked: Gentle exfoliation (often mentioned)
- Liked: Skin texture improvement (often mentioned)
- Disliked: Limited availability (often mentioned)
- Liked: Suitable for sensitive skin (sometimes noted)
- Disliked: Price point (sometimes noted)
- Disliked: Messy application (rarely noted)
- Disliked: Potential irritants (rarely noted)

## How to apply

- Could be used as part of your PM routine once a week. Always remember to wear SPF in the morning.
- Use as the third step in your weekly routine, after cleansing and before your hydrating toner. Apply only when following the weekly routine.
- Mix the enzyme powder exfoliant with a little water in your hands to create a paste. Gently pat onto your face and avoid rubbing.
- Apply the enzyme powder exfoliant on slightly damp skin for the best results. Clean skin helps the product work on your pigmentation.
- Avoid the eye area and do a patch test before first use. Do not combine this product with strong acids or retinoids in the same routine.
- Video: https://storage.pora.ai/767f9b79c33b777aa28f84f66e309d62.mp4

## Questions and answers

### What makes PHA Mild Enzyme Powder a great fit for skin with dark spots?

This enzyme powder exfoliant is a great fit because papain and bromelain provide gentle cleansing that helps fade dark spots, while ingredients like allantoin and sodium hyaluronate soothe the skin and keep it hydrated.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### Which ingredients make this exfoliant a good fit for skin with dark spots?

Papain and bromelain make this exfoliant a great fit for skin with dark spots by providing gentle enzymatic cleansing to help clear uneven tone. At the same time, ingredients like allantoin and glycerin soothe your skin, while sodium hyaluronate adds hydration and supports your skin barrier.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/)

### What does Papain do for skin with dark spots?

Papain helps smooth the skin by gently removing dead surface cells, which may improve overall texture over time. This type of ingredient works best for dark spots when combined with brightening agents and daily sun protection.
Sources: [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34897928/)

### What does Bromelain do for skin with dark spots?

Bromelain helps clear away surface layers of skin to remove unwanted pigment and dark spots. Topical use may reduce the time needed for skin to renew itself, with very low risk of side effects.
Sources: [Nutrition and Health, 2023](https://pubmed.ncbi.nlm.nih.gov/37157782/)

### Where does this exfoliant go in a skincare routine for skin with dark spots?

This enzyme powder exfoliant goes into your weekly routine once a week, after makeup remover and cleanser, followed by a nourishing mask, treatment, and moisturizer. It offers moderate exfoliation for dark spots using papain and bromelain, while keeping your skin calm with soothing ingredients.

### Can I use this exfoliant with retinol, and in what order?

You can use this enzyme powder exfoliant in your weekly routine, but avoid applying it on the same nights you use retinol to prevent irritation. On nights when you use retinol, skip the exfoliant and focus on gentle hydration and moisture.

### How often should I use this exfoliant?

Start by using this exfoliant once a week, and if your skin handles it well and you see good results, you can carefully use it more often. This gentle approach helps prevent irritation while managing dark spots with papain and bromelain.

### Can this exfoliant clog pores, cause breakouts or purging for skin with dark spots?

This exfoliant is unlikely to clog pores or cause breakouts for skin with dark spots because it features a gentle formula with soothing ingredients and no harsh components. It helps clear away dead skin cells smoothly while keeping your skin calm.

### Is this exfoliant fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for skin with dark spots

- [Dermalogica Daily Microfoliant](https://lovi.care/skincare/nl/p/dermalogica/daily-microfoliant/for/dark-spots) — High fit — €72.82 at Amazon
- [Eminence Organic Skin Care Strawberry Rhubarb Dermafoliant](https://lovi.care/skincare/nl/p/eminence-organic-skin-care/strawberry-rhubarb-dermafoliant/for/dark-spots) — High fit — €92.45 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/nl/p/cerave/foaming-facial-cleanser/for/dark-spots) — Superior fit — €21.00 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/nl/p/pyunkang-yul/calming-deep-moisture-toner/for/dark-spots) — Superior fit — €14.31 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/dark-spots) — Superior fit — €19.20 at Amazon

## Where to buy

No store in Netherlands has a checked price for this product, so the page shows none.

## Ingredients

Zea Mays Starch, Sodium Cocoyl Isethionate, Sodium Lauroyl Glutamate, Sodium Palmitate, Diglycerin, Allantoin, Maltodextrin, Papain, Bromelain, Gluconolactone, Sodium Hyaluronate, Lauryl Betaine, Sodium Chloride, Lactobacillus Punica Granatum Extract Fruit Ferment, Portulaca Oleracea Extract, Rosa Multiflora Fruit Extract, Ceratonia Siliqua Fruit Extract, Chenopodium Quinoa Seed Extract, Lens Esculenta Fruit Extract, Nelumbo Nucifera Seed Extract, Glycerin, 1,2-Hexanediol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cliv/pha-mild-enzyme-powder/for/dark-spots
- United Kingdom: https://lovi.care/skincare/uk/p/cliv/pha-mild-enzyme-powder/for/dark-spots
- Ireland: https://lovi.care/skincare/ie/p/cliv/pha-mild-enzyme-powder/for/dark-spots
- Germany: https://lovi.care/skincare/de/p/cliv/pha-mild-enzyme-powder/for/dark-spots
- France: https://lovi.care/skincare/fr/p/cliv/pha-mild-enzyme-powder/for/dark-spots
- Italy: https://lovi.care/skincare/it/p/cliv/pha-mild-enzyme-powder/for/dark-spots
- Netherlands: https://lovi.care/skincare/nl/p/cliv/pha-mild-enzyme-powder/for/dark-spots (this page)
- Spain: https://lovi.care/skincare/es/p/cliv/pha-mild-enzyme-powder/for/dark-spots
- Canada: https://lovi.care/skincare/ca/p/cliv/pha-mild-enzyme-powder/for/dark-spots
- Australia: https://lovi.care/skincare/au/p/cliv/pha-mild-enzyme-powder/for/dark-spots
- Singapore: https://lovi.care/skincare/sg/p/cliv/pha-mild-enzyme-powder/for/dark-spots
- Saudi Arabia: https://lovi.care/skincare/sa/p/cliv/pha-mild-enzyme-powder/for/dark-spots
- United Arab Emirates: https://lovi.care/skincare/ae/p/cliv/pha-mild-enzyme-powder/for/dark-spots