Cetaphil Redness Relieving Night Moisturizer for sensitive skin
Allantoin
Niacinamide
Panthenol Vitamin B5
Tocopheryl Acetate Vitamin E
Ceramide NpAverage
- HighNormal Skin Fit
- AverageEffectiveness
- HighSafety
Works for sensitive skin; other moisturizers fit it better.
- American Journal of Clinical Dermatology, 2002
- Clinical, Cosmetic and Investigational Dermatology, 2017
This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate moisturizing for your normal skin, as glycerin and sodium hyaluronate provide hydration while allantoin and panthenol soothe redness and irritation. Niacinamide further supports skin barrier function and reduces inflammation, enhancing overall comfort.
- The formulation is highly suitable for normal skin due to its humectant and soothing properties, effectively addressing your concerns.
- The safety profile is excellent, with no risks of irritation for your sensitive skin due to the absence of harsh ingredients and the presence of soothing components.
How to apply
- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
People Say
★4.4Overall rating based on 3.4k+ reviewsMany users report a visible reduction in redness and a calmer complexion by morning. A subset of reviewers find it functions better as a gentle maintenance moisturizer rather than a treatment that actively eliminates existing redness.
Highlights
Gentle & soothing Often Mentioned
- “feels soothing”
- “stops burning”
- “cools skin”
- “no stinging”
Lightweight texture Often Mentioned
- “absorbs quickly”
- “not greasy”
- “lightweight feel”
- “doesn't feel heavy”
Reduces redness Often Mentioned
- “less red in morning”
- “skin looks balanced”
- “stopped the flushing”
Fragrance-free Sometimes Noted
- “no scent”
- “doesn't irritate nose”
- “great for sensitive skin”
- “no chemical smell”
Hydrating Sometimes Noted
- “skin feels soft”
- “good moisture”
- “eliminates dry patches”
- “hydrates overnight”
Ineffective on redness Sometimes Noted
- “didn't help redness”
- “just a moisturizer”
- “no change in color”
- “redness persisted”
Caused irritation Rarely Noted
- “burned my face”
- “caused breakout”
- “stung upon application”
- “made face redder”
Packaging issues Rarely Noted
- “pump stopped working”
- “hard to get last bit”
- “defective dispenser”
- “wasteful bottle”
Small quantity Rarely Noted
- “bottle is tiny”
- “expensive for size”
- “runs out fast”
- “wish it was bigger”
Texture too thin Rarely Noted
- “too watery”
- “runny consistency”
- “not rich enough”
- “need more moisture”
Sources: lovi.care, walmart.com, target.com, iherb.com, cetaphil.com, walgreens.com, and more
Questions and answers
How well does Cetaphil Redness Relieving Night Moisturizer work for sensitive skin?
Cetaphil Redness Relieving Night Moisturizer works moderately well for sensitive skin, offering good hydration alongside soothing ingredients that help calm redness and irritation. To fit sensitive skin even better, a moisturizing treatment needs highly effective soothing components like fermented Centella Asiatica and cica ceramide, plus nourishing oils to strengthen the skin barrier without overwhelming it.
Which ingredients make this cream a good fit for sensitive skin?
Glycerin and sodium hyaluronate bring hydration, while allantoin and panthenol help calm redness and irritation. To fit sensitive skin even better, a moisturizing treatment of this type needs fermented Centella Asiatica, Cica Ceramide, and nourishing oils.
What does Allantoin do for sensitive skin?
Allantoin helps calm sensitive skin and keeps it comfortable by soothing irritation and reducing redness. It is frequently included in gentle face products because it has a very safe profile and supports the skin barrier well.
International Journal of Cosmetic Science, 2022Journal of Cosmetic Dermatology, 2022
What does Niacinamide do for sensitive skin?
Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
Where does it go in a skincare routine for sensitive skin?
This moisturizing treatment goes in the evening routine after your toner and before your moisturizer. Sensitive skin needs a product of this type that also delivers extra barrier-strengthening ceramides and soothing plant extracts.
Can I use this cream with retinol, and in what order?
You can use this cream with retinol by applying your retinol first and following with this moisturizer to help calm irritation and keep your skin soft. This routine is unlikely to cause irritation for your sensitive skin due to the soothing ingredients and lack of harsh components.
How often should I use it?
You can use this moisturizing treatment in your evening routine daily. Daily application of moisturizers helps keep your skin soft and smooth while supporting the skin barrier.
Can this cream clog pores, cause breakouts or purging for sensitive skin?
This cream is unlikely to cause irritation or breakouts for sensitive skin because it avoids harsh ingredients and includes soothing components like allantoin and panthenol. A product of this type for sensitive skin needs calming ingredients like niacinamide and ceramides alongside gentle hydrators to keep skin soft and comfortable.
American Journal of Clinical Dermatology, 2002The Journal of Dermatological Treatment, 2017
Can I use it around the eyes or on my body?
This moisturizer is safe to use around the eyes and on the body, as it has an excellent safety profile with soothing ingredients that help prevent irritation on thin or delicate skin. Sensitive skin needs a product of this type that features gentle hydrators and calming ingredients like glycerin, allantoin, and panthenol to keep the skin soft and comfortable.
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol, behenyl alcohol, and cetyl alcohol are fatty alcohols, which soften the skin.
What the research says
Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment.
American Journal of Clinical Dermatology, 2002A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability.
The Journal of Dermatological Treatment, 2017Emulsions containing ceramides 1 and 3 improved skin hydration and reduced transepidermal water loss in sodium lauryl sulfate-irritated skin of fifteen healthy Asian women compared to a control emulsion.
International Journal of Dermatology, 2008Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo.
Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment.
Aesthetic Plastic Surgery, 2018Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.
The Journal of Investigative Dermatology, 2008Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.
Dermatologic Surgery, 2005Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.
Journal of Cosmetic Dermatology, 2019Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans.
Arzneimittel-Forschung, 2000Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two.
Auris, Nasus, Larynx, 2020Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls.
Journal of Cosmetic Dermatology, 2025Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.
Contemporary Clinical Trials Communications, 2021Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin.
Journal of Cosmetic Dermatology, 2024
Ingredients
Water, Caprylic Capric Triglyceride, Glycerin, Propanediol, Pentylene Glycol, Helianthus Annuus Seed Oil Sunflower Seed Oil, Sorbitol, Dimethicone, Butyrospermum Parkii Butter Shea Butter, Cetearyl Alcohol, Behenyl Alcohol, Glyceryl Stearate, Sodium Hydroxide, Tocopheryl Acetate, Allantoin, Dipotassium Glycyrrhizate, Sodium Hyaluronate, Ceramide Np, Panthenol, Caffeine, Citric Acid, Cetyl Alcohol, Ceteareth-20, Glyceryl Stearate Citrate, Disodium Ethylene Dicocamide Peg-15 Disulfate, Niacinamide, Caprylyl Glycol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Disodium Edta, Xanthan Gum, Bht
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
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