# Cetaphil Daily Facial Moisturizer for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/nl/p/cetaphil/daily-facial-moisturizer/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Cetaphil](https://lovi.care/skincare/nl/brands/cetaphil)
Category: [Sunscreens and SPF moisturizers](https://lovi.care/skincare/nl/best/sunscreens)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few sunscreens fit it even better.

## Why this fit

- Offers excellent sun protection for your combination skin due to avobenzone and octocrylene, while niacinamide and panthenol help soothe inflammation and reduce breakouts.
- Glycerin and niacinamide work synergistically to balance oil production and hydration, making it highly suitable for combination skin.
- The product is safe for your acne-prone skin, as it contains no harsh or prohibited ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/cetaphil/daily-facial-moisturizer/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/nl/p/cetaphil/daily-facial-moisturizer/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/nl/p/cetaphil/daily-facial-moisturizer/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/nl/p/cetaphil/daily-facial-moisturizer/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/nl/p/cetaphil/daily-facial-moisturizer/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/nl/p/cetaphil/daily-facial-moisturizer/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/nl/p/cetaphil/daily-facial-moisturizer/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/cetaphil/daily-facial-moisturizer/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/cetaphil/daily-facial-moisturizer/for/oily-acne-prone-skin): High

## Key ingredients

Avobenzone, Octocrylene, Glycerin, Niacinamide, Tocopheryl Acetate Vitamin E

## What the research says

- Incorporating rosmarinic acid into sunscreens enhanced the in vivo SPF of octocrylene by over 157% and reduced lipid peroxidation in the human stratum corneum. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40227214/))
- Encapsulating avobenzone in low-porosity TiO2-embedded mesoporous silica (TiO2/SBA-S) reduced cutaneous avobenzone absorption from 0.76 to 0.50 nmol/mg while providing effective pollutant adsorbability, UVA protection, and a two- to three-fold reduction in photoaged skin cytokines/chemokines compared to the non-treatment control. ([European Journal of Pharmaceutical Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/36455708/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The application of a sunscreen formulation containing ethylhexyl methoxycinnamate, ethylhexyl salicylate, methyl anthranilate, and octocrylene does not significantly affect critical acne-related species such as Cutibacterium acnes and Staphylococcus epidermidis, refuting the induction of facial dysbiosis in men. ([Archives of Dermatological Research, 2024](https://pubmed.ncbi.nlm.nih.gov/39499337/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Encapsulation of ethylhexyl methoxycinnamate and butyl methoxydibenzoylmethane in lipid microparticles significantly reduced their in vivo human skin penetration compared to nonencapsulated filters. ([Skin Pharmacology and Physiology, 2011](https://pubmed.ncbi.nlm.nih.gov/21336009/))
- Microencapsulation of the BMDBM/HP-beta-CD complex in lipid microparticles significantly decreased the percutaneous penetration of the UV filter into the stratum corneum of human volunteers compared to the non-encapsulated sunscreen agent. ([Journal of Pharmaceutical and Biomedical Analysis, 2011](https://pubmed.ncbi.nlm.nih.gov/20934293/))
- Following human skin application of an O/W emulsion containing 2% BMDBM loaded in lipospheres, 15% of the sunscreen accumulated in the uppermost layers of the stratum corneum without remarkably modifying skin permeation compared to unencapsulated sunscreen. ([Skin Pharmacology and Physiology, 2008](https://pubmed.ncbi.nlm.nih.gov/17934329/))
- Early application of sunscreen after ablative fractional skin resurfacing significantly increased the sensitization rate of the UV-filter, octocrylene, and the sunscreen compared to intact skin. ([The Journal of Dermatological Treatment, 2015](https://pubmed.ncbi.nlm.nih.gov/25633273/))
- Dermal sunscreen exposure in 20 healthy volunteers led to plasma concentrations of avobenzone, octocrylene, and its metabolite CDAA reaching up to 11 μg/L, 25 μg/L, and 1352 μg/L, respectively. ([Environment International, 2019](https://pubmed.ncbi.nlm.nih.gov/31470219/))
- Chemical sunscreens containing avobenzone, octocrylene, homosalate, and octisalate showed no to minimal risks of dermal irritation, sensitization, photo-allergy, and photo-irritation in human subjects. ([Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40911743/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- A topical antioxidant serum significantly reduced air pollution-induced skin pigmentation and proinflammatory gene expression ex vivo, and improved skin aging signs in 40 healthy adult females after 90 days of daily use. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35150043/))

## What reviewers say

Based on a very large amount of data, users with sensitive and combination skin frequently praise this moisturizer for being lightweight and non-irritating, often noting it provides effective hydration without clogging pores or causing acne breakouts. A notable subset of users experiences a burning or stinging sensation upon application, and those with darker skin tones often report a visible white cast, particularly with the SPF 35 and SPF 50 versions.

- Liked: Gentle for sensitive skin (often mentioned)
- Liked: Lightweight & non-greasy (often mentioned)
- Liked: Effective hydration (sometimes noted)
- Liked: Fragrance-free (sometimes noted)
- Disliked: Burning sensation (sometimes noted)
- Disliked: White cast (sometimes noted)
- Disliked: Eye irritation (rarely noted)
- Disliked: Greasy finish (rarely noted)

## How to apply

- Apply this moisturizing sunscreen AM every morning as the final step of your daily routine.
- Layer the moisturizing sunscreen after your moisturizer has fully absorbed, right before heading out into the sun .
- Smooth a nickel-sized amount of the moisturizing sunscreen evenly over your face, avoiding harsh rubbing.
- Apply the moisturizing sunscreen onto clean, dry skin to ensure even coverage and protection.
- Perform a patch test before first use and avoid direct contact with the eyes.
- Video: https://storage.pora.ai/53e9a436d82fca2a189dd08aa21de2fd.mp4

## Questions and answers

### What makes Cetaphil Daily Facial Moisturizer a great fit for acne-prone skin?

Cetaphil Daily Facial Moisturizer is a great fit for acne-prone skin because it offers sun protection while niacinamide and panthenol help soothe inflammation and reduce breakouts. Glycerin and niacinamide also work together to balance oil and hydration without causing irritation.
Sources: [Archives of Dermatological Research, 2024](https://pubmed.ncbi.nlm.nih.gov/39499337/), [Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/)

### Which ingredients make this moisturizer a good fit for acne-prone skin?

Niacinamide and panthenol help soothe inflammation and reduce breakouts, while glycerin helps balance oil and hydration. It is safe for acne-prone skin because it contains no harsh or prohibited ingredients that could cause irritation.

### What does Avobenzone do for acne-prone skin?

Avobenzone protects acne-prone skin from UV rays that can worsen dark spots and inflammation, though it does not directly treat breakouts. To properly care for acne-prone skin, sunscreens should also feel light, clog-free, and non-greasy.
Sources: [American Journal of Clinical Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/19209950/)

### What does Octocrylene do for acne-prone skin?

Octocrylene is a sunscreen ingredient that protects acne-prone skin from UV rays without disturbing the balance of bacteria living on the face. It is unlikely to trigger breakouts, but a sunscreen for this skin type still needs a lightweight, non-greasy texture and ingredients that do not clog pores.
Sources: [Archives of Dermatological Research, 2024](https://pubmed.ncbi.nlm.nih.gov/39499337/)

### Where does this moisturizer go in a skincare routine for acne-prone skin?

This moisturizer goes in the morning step of your routine right after your hydrating toner and before your sunscreen. It is a great fit for your acne-prone skin because ingredients like glycerin and niacinamide balance oil and hydration while soothing inflammation.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/)

### Can I use this moisturizer with retinol, and in what order?

You can use this moisturizer with retinol by applying your retinol first and following it with this product to keep your skin calm and hydrated. Using a moisturizing cream with active ingredients like niacinamide and panthenol helps soothe inflammation and supports your skin barrier while you use retinoids.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22648223/)

### How often should I use this moisturizer?

You can use this moisturizer every morning as part of your daily routine to protect your skin and keep it hydrated. Its formula helps calm breakouts and balance oil production safely without causing irritation.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Archives of Dermatological Research, 2024](https://pubmed.ncbi.nlm.nih.gov/39499337/)

### Can this moisturizer clog pores, cause breakouts or purging for acne-prone skin?

This moisturizer is a great fit for acne-prone skin because it contains no harsh or prohibited ingredients that are likely to cause irritation or breakouts. Glycerin and niacinamide work together to balance oil and hydration, while vitamin E has been shown in studies to have a safe, non-comedogenic profile.
Sources: [Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/)

### Is this moisturizer fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for acne-prone skin

- [Olay Regenerist Micro-Sculpting Cream SPF 30](https://lovi.care/skincare/nl/p/olay/regenerist-micro-sculpting-cream-face-moisturizer-with-spf-30/for/acne-prone-skin) — High fit — €59.97 at Amazon
- [Perricone MD Vitamin C Ester Photo-Brightening Moisturizer SPF 30](https://lovi.care/skincare/nl/p/perricone-md/vitamin-c-ester-photo-brightening-moisturizer-spf-30/for/acne-prone-skin) — High fit — €74.15 at Amazon
- [Olay Regenerist Whip Face Moisturizer SPF 40](https://lovi.care/skincare/nl/p/olay/regenerist-whip-face-moisturizer-with-sunscreen-spf-40/for/acne-prone-skin) — High fit — €68.55 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/nl/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — €19.90 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — €19.20 at Amazon

## Where to buy

- Amazon.nl: €30.52 (https://www.amazon.nl/dp/B07TZ56QF8?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €16.13 (https://www.lookfantastic.nl/p/cetaphil-daily-hydrating-moisturiser-88ml/13105756/)
- Notino: €15.50 (https://www.notino.nl/cetaphil/daily-defence-face-moisturiser-beschermende-huidcreme-spf-30/p-16375418/)
Prices checked 10 Oct – 6 Nov 2026.

## Ingredients

Water, Glycerin, Dipropylene Glycol, Panthenol Vitamin B5, Ethylhexyl Methoxycrylene, Isopropyl Palmitate, Silica, Niacinamide, Cetearyl Olivate, Cetearyl Alcohol, Glyceryl Stearate, Potassium Cetyl Phosphate, Sorbitan Olivate, Tocopheryl Acetate Vitamin E Acetate, Caprylyl Glycol, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Palmitic Acid, Ethylhexylglycerin, Leontopodium Extract Leontopodium Alpinum Extract, Stearic Acid, 1,2-Hexanediol, Rice Extract Lees Extract, Propanediol, Sodium Hydroxide, Adenosine, Potassium Sorbate, Sodium Benzoate, Citric Acid, Myristic Acid, Buddleja Davidii Leaf Extract, Thymus Vulgaris Leaf Extract, Tocopherol Vitamin E, Avobenzone, Octocrylene
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/cetaphil/daily-facial-moisturizer/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/cetaphil/daily-facial-moisturizer/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/cetaphil/daily-facial-moisturizer/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/cetaphil/daily-facial-moisturizer/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/cetaphil/daily-facial-moisturizer/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/cetaphil/daily-facial-moisturizer/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/cetaphil/daily-facial-moisturizer/for/acne-prone-skin (this page)
- Spain: https://lovi.care/skincare/es/p/cetaphil/daily-facial-moisturizer/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/cetaphil/daily-facial-moisturizer/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/cetaphil/daily-facial-moisturizer/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/cetaphil/daily-facial-moisturizer/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/cetaphil/daily-facial-moisturizer/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/cetaphil/daily-facial-moisturizer/for/acne-prone-skin