# Centellian24 Madeca Cream for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/nl/p/centellian24/madeca-cream/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Centellian24](https://lovi.care/skincare/nl/brands/centellian24)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/nl/best/moisturizers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your normal skin, this product effectively addresses redness and irritation with Centella Asiatica Extract and Madecassic Acid, which calm and strengthen your skin barrier.
- Niacinamide and Allantoin further support barrier repair and soothing, ensuring comprehensive care for your sensitive skin.
- The formulation is safe for sensitive skin, avoiding harsh ingredients and incorporating soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/centellian24/madeca-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/nl/p/centellian24/madeca-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/nl/p/centellian24/madeca-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/nl/p/centellian24/madeca-cream/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/nl/p/centellian24/madeca-cream/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/nl/p/centellian24/madeca-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/nl/p/centellian24/madeca-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/centellian24/madeca-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/centellian24/madeca-cream/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica, Madecassoside, Teca Extract Titrated Of Centella Asiatica Extract, Niacinamide, Sodium Hyaluronate

## What the research says

- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Treatment with an asiaticoside-containing cream applied twice daily for 12 weeks significantly improved periorbital wrinkles in 65% of 27 female volunteers compared to a vehicle control cream. ([International Journal of Cosmetic Science, 2008](https://pubmed.ncbi.nlm.nih.gov/18452433/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Based on a very large amount of data, this cream is highly praised for its barrier repair and anti-aging benefits, delivering a radiant glow and soothing sensitive skin. It is particularly effective for dry and mature skin types. However, individuals with oily or acne-prone skin may find it too heavy, potentially leading to congestion.

- Liked: Intense hydration glow (often mentioned)
- Liked: Soothing barrier repair (often mentioned)
- Disliked: Strong herbal scent (often mentioned)
- Liked: Anti-aging effects (sometimes noted)
- Liked: Rich absorbent texture (sometimes noted)
- Disliked: Greasy/sticky finish (sometimes noted)
- Disliked: Causes breakouts (rarely noted)
- Disliked: Packaging issues (rarely noted)

## How to apply

- Use this soothing AM and PM routine every day to keep your normal skin calm. Always remember to apply SPF in the morning after your moisturizer.
- Apply your moisturizer after your toner in the morning, and after your serum in the evening. This step locks in hydration and protects your skin.
- Gently press a small amount of the moisturizer evenly across your face. Avoid rubbing to keep your sensitive skin happy and calm.
- You can apply this gentle formula on dry or slightly damp skin for the best comfort. It works wonderfully on clean skin to soothe redness and irritation.
- Do a patch test before your very first use to check your skin's reaction. Avoid getting the product directly into your eyes .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Centellian24 Madeca Cream a great fit for sensitive skin?

Centellian24 Madeca Cream is a great fit for sensitive skin because it helps calm redness and irritation while supporting your skin barrier with Centella Asiatica, Madecassic Acid, and Niacinamide. The formula is safe for sensitive skin as it leaves out harsh ingredients and includes soothing components.
Sources: [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this cream a good fit for sensitive skin?

This cream is a great fit for sensitive skin because it contains Centella Asiatica and Madecassic Acid, which help calm redness and irritation while strengthening your skin barrier. Niacinamide and Allantoin further support barrier repair and soothing, providing gentle and comprehensive care.
Sources: [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Centella Asiatica do for sensitive skin?

Centella asiatica helps calm sensitive skin and keeps it feeling soft by soothing irritation and supporting the skin barrier. It is unlikely to cause trouble and may help reduce redness and discomfort over a few weeks of regular use.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40682399/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Madecassoside do for sensitive skin?

Madecassoside helps calm sensitive skin by reducing irritation and supporting skin barrier repair. It also has soothing properties that may decrease redness and discomfort.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Planta Medica, 2010](https://pubmed.ncbi.nlm.nih.gov/19774506/)

### Where does this cream go in a skincare routine for sensitive skin?

This cream goes in the evening routine as a treatment, applied after your cleanser and soothing toner. It is a great fit for sensitive skin because it uses Centella Asiatica and Madecassic Acid to help calm redness and irritation while strengthening your skin barrier.
Sources: [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol, and applying it after your retinol helps calm and comfort sensitive skin. Centella Asiatica and Niacinamide support barrier repair and may reduce the irritation often caused by strong actives.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

You can use this moisturizing treatment twice a day as part of your routine. Regular daily application helps keep your skin calm and hydrated while supporting your skin barrier.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for sensitive skin?

This moisturizing treatment is unlikely to cause breakouts for sensitive skin, as it avoids harsh ingredients and features a safe, soothing profile. Reviewers rarely report breakouts, and its calming ingredients help keep skin clear and comfortable.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Can I use this cream around the eyes or on my body?

This cream is generally suitable for use around the eyes and on the body because its soothing ingredients are very well tolerated by delicate skin. Clinical studies on similar moisturizing creams show they can safely improve skin texture in these areas without causing irritation.
Sources: [European Journal of Pharmaceutics and Biopharmaceutics, 2014](https://pubmed.ncbi.nlm.nih.gov/24056055/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (limonene).

## Alternatives for sensitive skin

- [COSRX Advanced Snail 92 All in One Cream](https://lovi.care/skincare/nl/p/cosrx/advanced-snail-92-all-in-one-cream/for/sensitive-skin) — Superior fit — €9.99 at Amazon
- [belif The True Cream Aqua Bomb](https://lovi.care/skincare/nl/p/belif/the-true-cream-aqua-bomb/for/sensitive-skin) — High fit — €35.96 at Amazon
- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/nl/p/the-ordinary/natural-moisturizing-factors-ha/for/sensitive-skin) — High fit — €13.02 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — €21.95 at Amazon
- Soothing Toner: [SKIN1004 Centella Asiatica Toning Toner](https://lovi.care/skincare/nl/p/skin1004/centella-asiatica-toning-toner/for/sensitive-skin) — Superior fit — €17.96 at Amazon
- Moisturizer with Sun Protection: [Bioderma Bioderma Photoderm Mineral SPF 50+](https://lovi.care/skincare/nl/p/bioderma/photoderm-mineral-fluide-spf50/for/sensitive-skin) — Superior fit — €19.79 at Amazon

## Where to buy

- Amazon.nl: €17.41 (https://www.amazon.nl/dp/B0DFY92NDB?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- Notino: €48.00 (https://www.notino.nl/centellian24/madeca-cream-time-reverse-signature-edition-gift-set-voor-herstel-van-huidstevigheid/p-16397143/)
Prices checked 17 Oct – 5 Nov 2026.

## Ingredients

Centella Asiatica Extract, Cyclohexasiloxane, Niacinamide, Dicaprylyl Ether, 1,2-Hexanediol, C14-22 Alcohols, Dipropylene Glycol, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Ficus Carica Fruit Extract, Monarda Didyma Leaf Extract, Chrysanthemum Parthenium Extract Feverview Extract, Salvia Officinalis Leaf Water, Water-Soluble Collagen, Citrus Aurantium Dulcis Peel Oil, Hydrogenated Lecithin, Olea Europaea Oil Fruit Olive Oil Fruit, Centella Asiatica Oil, Polyglyceryl-10 Laurate, Sodium Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Water, Dimethicone Vinyl Dimethicone Crosspolymer, Polyisobutene, C12-20 Alkyl Glucoside, Glyceryl Stearate Se, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Beta-Glucan, Sorbitan Oleate, Caprylyl Capryl Glucoside, Adenosine, Fructooligosaccharides, Sodium Stearoyl Glutamate, Disodium Edta, Glycerin, Sodium Laurate, Allantoin, Hydrolyzed Hyaluronic Acid, Lauric Acid, Madecassic Acid, Asiaticoside, Glucose, Asiatic Acid, Ceramide Np, Soluble Proteoglycan, Elastin, Sodium Hyaluronate, Polysorbate 60, Ethylhexylglycerin, Limonene
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/centellian24/madeca-cream/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/centellian24/madeca-cream/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/centellian24/madeca-cream/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/centellian24/madeca-cream/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/centellian24/madeca-cream/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/centellian24/madeca-cream/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/centellian24/madeca-cream/for/sensitive-skin (this page)
- Spain: https://lovi.care/skincare/es/p/centellian24/madeca-cream/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/centellian24/madeca-cream/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/centellian24/madeca-cream/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/centellian24/madeca-cream/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/centellian24/madeca-cream/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/centellian24/madeca-cream/for/sensitive-skin