# Calmoseptine Ointment for combination skin **Lovi Fit: Warning fit for combination skin.** Combination Skin Fit: Average · Effectiveness: Average · Safety: Warning. Page: https://lovi.care/skincare/nl/p/calmoseptine/ointment/for/combination-skin The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands. Brand: [Calmoseptine](https://lovi.care/skincare/nl/brands/calmoseptine) This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app. A poor match for combination skin; the products alongside fit it better. ## Fit by skin type - [Oily skin](https://lovi.care/skincare/nl/p/calmoseptine/ointment/for/oily-skin): Warning - [Dry skin](https://lovi.care/skincare/nl/p/calmoseptine/ointment/for/dry-skin): Warning - [Combination skin](https://lovi.care/skincare/nl/p/calmoseptine/ointment/for/combination-skin): Warning (this page) - [Sensitive skin](https://lovi.care/skincare/nl/p/calmoseptine/ointment/for/sensitive-skin): Warning - [Acne-prone skin](https://lovi.care/skincare/nl/p/calmoseptine/ointment/for/acne-prone-skin): Warning - [Skin with dark spots](https://lovi.care/skincare/nl/p/calmoseptine/ointment/for/dark-spots): Warning - [Mature skin](https://lovi.care/skincare/nl/p/calmoseptine/ointment/for/mature-skin): Warning - [Dry sensitive skin](https://lovi.care/skincare/nl/p/calmoseptine/ointment/for/dry-sensitive-skin): Warning - [Oily acne-prone skin](https://lovi.care/skincare/nl/p/calmoseptine/ointment/for/oily-acne-prone-skin): Warning ## Key ingredients Menthol, Zinc Oxide, Calamine, Chlorothymol, Glycerin ## What the research says - Coadministration of 40% topical L-menthol with 10% trans-cinnamaldehyde reduced spontaneous pain intensity, neurogenic inflammation, primary and secondary mechanical hyperalgesia, and heat hyperalgesia, but not cold hyperalgesia, in 14 healthy volunteers. ([The Journal of Pain, 2016](https://pubmed.ncbi.nlm.nih.gov/27260636/)) - Topical application of menthol-based cooling gel decreased intramuscular temperature by 1.9 °C and increased cutaneous blood flow by 0.3 ml/min in healthy males compared to placebo gel. ([International Journal of Sports Physical Therapy, 2018](https://pubmed.ncbi.nlm.nih.gov/30038834/)) - Cooling skin temperature or applying topical menthol reduced histamine-induced itch intensity and flare diameters in healthy male volunteers. ([Neuroscience Letters, 1995](https://pubmed.ncbi.nlm.nih.gov/7624016/)) - Topical 0.5% hyaluronic-ZnO nanogel applied twice daily reduced inflammatory-lesion counts by 58% at week four in human subjects compared to baseline without causing erythema. ([Biomedicines, 2025](https://pubmed.ncbi.nlm.nih.gov/41007718/)) - Nels cream achieved a similar reduction in inflammatory and noninflammatory lesion counts compared to 5% benzoyl peroxide in acne vulgaris patients, but caused significantly fewer side-effects such as peeling and dryness. ([Clinical and Experimental Dermatology, 2000](https://pubmed.ncbi.nlm.nih.gov/10671963/)) - Topically applied coated and uncoated zinc oxide nanoparticles under flexing and massage are retained in the stratum corneum with no significant penetration into the viable epidermis and no cellular toxicity in human skin. ([Nanomedicine, 2016](https://pubmed.ncbi.nlm.nih.gov/27102240/)) - Topical zinc oxide 20% ointment achieved a complete cure in 50% of patients with warts compared to 42% in the salicylic acid-lactic acid group, with no serious side-effects. ([International Journal of Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17442091/)) - A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)) - The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/)) - Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/)) ## Questions and answers ### Why does Lovi advise against Calmoseptine Ointment for combination skin? This ointment is a poor match because it lacks the ingredients needed to balance oily and dry areas on combination skin, such as niacinamide, propolis, or zinc PCA to manage shine and provide proper hydration without irritation. ### Which ingredients make this ointment a poor fit for combination skin? This ointment is a poor fit for combination skin because it uses heavy ingredients like lanolin and zinc oxide meant to block moisture and protect raw areas, which can feel too thick and clog the oily parts of your face. Combination skin needs lighter ingredients like niacinamide, zinc PCA, and propolis to balance oily shine and keep the skin hydrated without feeling greasy. ### What does Menthol do for combination skin? Menthol helps cool combination skin and may calm itchy feelings. It gives a refreshing sensation, but because it can sometimes dry out certain areas, it is unlikely to suit flaky or sensitive spots without extra moisture. Sources: [Neuroscience Letters, 1995](https://pubmed.ncbi.nlm.nih.gov/7624016/), [The British Journal of Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38345103/) ### What does Zinc Oxide do for combination skin? Zinc oxide helps calm oily and breakout-prone areas while protecting dry spots without clogging pores. This ingredient is unlikely to cause irritation and safely manages shine and redness. Sources: [Journal of Controlled Release, 2025](https://pubmed.ncbi.nlm.nih.gov/40254135/), [Dermatologic Therapy, 2018](https://pubmed.ncbi.nlm.nih.gov/29193602/) ### Where does this ointment go in a skincare routine for combination skin? This ointment is a poor match for combination skin, so it is best to skip it in your routine. Combination skin needs lightweight hydrators and gentle balancing ingredients rather than heavy barrier ointments. ### Can I use this ointment with hydrocortisone, and in what order? It is generally best to ask your doctor before layering this ointment with hydrocortisone, as combining active medicated products can sometimes cause unexpected irritation. If your doctor approves, apply the hydrocortisone first and let it absorb completely before adding this ointment on top to seal it in. ### How often should I use this ointment? This ointment is a poor match for combination skin, so it is best to avoid using it daily or regularly on your face. A product of this type needs soothing and balancing ingredients like glycerin to hydrate dry areas without making oily zones greasy. ### Can this ointment clog pores, cause breakouts or purging for combination skin? This ointment is a poor match for combination skin and may clog pores or cause breakouts because it is a very thick barrier cream with lanolin and heavy ingredients meant to protect irritated skin rather than balance oily and dry areas. Combination skin needs a lightweight moisturizer with glycerin or hyaluronic acid to hydrate dry spots without trapping oil. ### Is this ointment fragrance-free and alcohol-free? Yes, it has no fragrance and no drying alcohol. ## Alternatives for combination skin - [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/nl/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — €10.20 at Amazon - [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — €35.80 at Amazon - [Herbivore Botanicals Blue Tansy Resurfacing Clarity Mask](https://lovi.care/skincare/nl/p/herbivore-botanicals/blue-tansy-bha-and-enzyme-pore-refining-mask/for/combination-skin) — Superior fit — €139.77 at Amazon ## Routine for combination skin ### AM - Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/nl/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — €16.50 at Amazon - Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon - Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/combination-skin) — Superior fit — €19.20 at Amazon - SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — €33.70 at Amazon ### PM - Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/combination-skin) — Superior fit — €11.83 at Amazon - Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/nl/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — €16.50 at Amazon - Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/nl/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — €16.99 at Amazon - Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/nl/p/peach-and-lily/glass-skin-refining-serum/for/combination-skin) — Superior fit — €86.59 at Amazon - Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/combination-skin) — Superior fit — €19.20 at Amazon ### Weekly - Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/combination-skin) — Superior fit — €11.83 at Amazon - Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/nl/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — €16.50 at Amazon - Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/nl/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — €16.99 at Amazon - Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/nl/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — €15.72 at Amazon - Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon - Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/nl/p/peach-and-lily/glass-skin-refining-serum/for/combination-skin) — Superior fit — €86.59 at Amazon ## Where to buy No store in Netherlands has a checked price for this product, so the page shows none. ## Ingredients Menthol, Zinc Oxide, Calamine, Chlorothymol, Glycerin, Lanolin, Phenol, Sodium Bicarbonate, Thymol ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/p/calmoseptine/ointment/for/combination-skin - United Kingdom: https://lovi.care/skincare/uk/p/calmoseptine/ointment/for/combination-skin - Ireland: https://lovi.care/skincare/ie/p/calmoseptine/ointment/for/combination-skin - Germany: https://lovi.care/skincare/de/p/calmoseptine/ointment/for/combination-skin - France: https://lovi.care/skincare/fr/p/calmoseptine/ointment/for/combination-skin - Italy: https://lovi.care/skincare/it/p/calmoseptine/ointment/for/combination-skin - Netherlands: https://lovi.care/skincare/nl/p/calmoseptine/ointment/for/combination-skin (this page) - Spain: https://lovi.care/skincare/es/p/calmoseptine/ointment/for/combination-skin - Canada: https://lovi.care/skincare/ca/p/calmoseptine/ointment/for/combination-skin - Australia: https://lovi.care/skincare/au/p/calmoseptine/ointment/for/combination-skin - Singapore: https://lovi.care/skincare/sg/p/calmoseptine/ointment/for/combination-skin - Saudi Arabia: https://lovi.care/skincare/sa/p/calmoseptine/ointment/for/combination-skin - United Arab Emirates: https://lovi.care/skincare/ae/p/calmoseptine/ointment/for/combination-skin