# BYOMA Clarifying Serum for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/nl/p/byoma/clarifying-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [BYOMA](https://lovi.care/skincare/nl/brands/byoma)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your normal skin, niacinamide and sodium hyaluronate provide humectant action and barrier repair, while gluconolactone offers moderate exfoliation and blemish reduction.
- Glycerin and sodium hyaluronate offer general hydration benefits, though they are not specialized for targeting wrinkles and fine lines.
- The product is safe for your normal skin with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/byoma/clarifying-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/nl/p/byoma/clarifying-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/nl/p/byoma/clarifying-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/nl/p/byoma/clarifying-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/nl/p/byoma/clarifying-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/nl/p/byoma/clarifying-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/nl/p/byoma/clarifying-serum/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/byoma/clarifying-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/byoma/clarifying-serum/for/oily-acne-prone-skin): High

## Key ingredients

Tri-Ceramide Complex, Blue Tansy, Niacinamide, Zinc, Gluconolactone

## What the research says

- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))
- Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients. ([The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of a ceramide complex cream significantly ameliorated lactic acid sensations and increased stratum corneum total ceramide content in 39 female subjects with sensitive skin compared with placebo. ([Archives of Dermatological Research, 2018](https://pubmed.ncbi.nlm.nih.gov/29728858/))
- A canine-specific ceramide complex consisting of a 4:1 ratio of CER [NS] to [EOP] reduced proinflammatory cytokine expression, upregulated skin barrier-related genes and enzymes, improved stratum corneum organization, and accelerated skin barrier repair in vitro and in vivo. ([Animals, 2026](https://pubmed.ncbi.nlm.nih.gov/42511026/))
- Topical chamazulene treatment mitigates UVB-induced photoaging in mouse skin by upregulating fatty acid metabolism genes, restoring fatty acid homeostasis, enhancing non-essential amino acid metabolism, and downregulating the p38 MAPK/COX-2 pathway, likely via PPARα/γ activation. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/41300477/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical zinc treatment enhanced MMP-1 expression beneath the neoepidermis and metallothionein expression under the neoepidermis and in the wound bed in human epidermal wounds compared to placebo and control treatments. ([European Journal of Cell Biology, 2021](https://pubmed.ncbi.nlm.nih.gov/33485703/))
- Topical preparations containing zinc(II) complexes with glycine and histidine effectively treat acne skin by providing high antibacterial activity against C. acnes and low cytotoxicity for skin cells, with no observed irritation or allergy in healthy volunteers. ([International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/33561977/))
- Topical copper and zinc formulations promote skin healing by exerting antimicrobial effects, modulating macrophage polarization, acting as enzyme cofactors, stimulating angiogenesis, and supporting re-epithelialization. ([Dermatology and Therapy, 2026](https://pubmed.ncbi.nlm.nih.gov/41205051/))
- Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/))
- Gluconolactone and tartaric acid significantly lower transepidermal water loss and erythema after sodium lauryl sulphate challenge compared to vehicle, untreated control, and glycolic acid in healthy subjects. ([The British Journal of Dermatology, 1997](https://pubmed.ncbi.nlm.nih.gov/9470910/))
- A polyhydroxy acid skin care regimen provided antiaging benefits comparable to an alpha-hydroxyacid regimen while demonstrating enhanced mildness and better tolerance in subjects. ([Cutis, 2004](https://pubmed.ncbi.nlm.nih.gov/15002657/))

## What reviewers say

Based on a very large amount of data, users with oily, acne-prone, and sensitive skin frequently praise this serum for its ability to clear breakouts and reduce redness without stripping the skin barrier. Many report smoother texture and unclogged pores, while a minority of reviewers found the formula sticky or ineffective for their specific skin concerns.

- Liked: Clears acne (mostly mentioned)
- Liked: Gentle and soothing (often mentioned)
- Liked: Great value (sometimes noted)
- Liked: Hydrating formula (sometimes noted)
- Liked: Improves texture (sometimes noted)
- Disliked: Sticky texture (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: No visible results (rarely noted)
- Disliked: Packaging issues (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes BYOMA Clarifying Serum a great fit for mature skin?

BYOMA Clarifying Serum is a great fit because niacinamide and sodium hyaluronate provide hydration and barrier support while gluconolactone gently exfoliates. These ingredients help keep skin looking smooth and calm without harsh risks.
Sources: [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/), [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which ingredients make this serum a good fit for mature skin?

Niacinamide and sodium hyaluronate make this serum a good fit for mature skin by helping improve aging signs, while gluconolactone provides gentle exfoliation without irritation. Glycerin further supports this by keeping the skin hydrated.
Sources: [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/), [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What do Ceramides do for mature skin?

Ceramides help mature skin by rebuilding the moisture barrier, increasing hydration, and improving texture and firmness. Topical application of ceramides is unlikely to cause irritation and may significantly reduce dryness in aging skin.
Sources: [Experimental Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39912256/), [International Journal of Immunopathology and Pharmacology, 2008](https://pubmed.ncbi.nlm.nih.gov/18336739/)

### What does Blue Tansy do for mature skin?

Blue Tansy helps calm dry or irritated mature skin and may reduce the look of redness. This plant extract brings soothing benefits that keep skin feeling soft and comfortable.

### Where does this serum go in a skincare routine for mature skin?

This treatment serum goes in the evening routine after your cleansing toner and before your moisturizer. It is very safe for your skin and is unlikely to cause irritation.

### Can I use it with retinol, and in what order?

You can use this treatment alongside retinol, but apply your retinol first and let it absorb before adding this serum to avoid irritation. Using gentle ingredients like niacinamide alongside retinoids is unlikely to cause problems and may even help soothe your skin.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/), [Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/)

### How often should I use this serum?

Use this treatment in your evening routine once a week to start. You may carefully use it more often if your skin tolerates it well and you see good results.

### Can it clog pores, cause breakouts or purging for mature skin?

It is unlikely to clog pores or cause breakouts for mature skin as it has a safe formula without harsh ingredients, though a low number of reviewers did report minor breakouts. The gentle exfoliator and barrier-supporting ingredients help keep skin clear and smooth.
Sources: [The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/nl/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — €160.00 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — €35.50 at Amazon
- [La Mer The Regenerating Serum](https://lovi.care/skincare/nl/p/la-mer/the-regenerating-serum/for/mature-skin) — High fit — €419.00 at Amazon

## Pairs well with

- Cleanser: [d'Alba White Truffle Return Oil Cream Cleanser](https://lovi.care/skincare/nl/p/d-alba/white-truffle-return-oil-cream-cleanser/for/mature-skin) — Superior fit — €25.07 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/mature-skin) — Superior fit — €19.90 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/nl/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — €48.84 at Amazon

## Where to buy

No store in Netherlands has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Niacinamide, 1,2-Hexanediol, Polyglyceryl-10 Laurate, Gluconolactone, Glyceryl Caprylate, Ceramide Np, Cholesterol, Caprylic Capric Triglyceride, Phytosphingosine, Stearic Acid, Oleic Acid, Zinc Lactate, Hydrogenated Lecithin, Ethylhexylglycerin, Sodium Hyaluronate, Tanacetum Annuum Oil Flower, Hydroxyethylcellulose, Ammonium Acryloyldimethyltaurate Vp Copolymer, Glyceryl Acrylate Acrylic Acid Copolymer, Sodium Phytate, Tocopherol, Lactic Acid, Caprylyl Glycol, Caprylhydroxamic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/byoma/clarifying-serum/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/byoma/clarifying-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/byoma/clarifying-serum/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/byoma/clarifying-serum/for/mature-skin
- France: https://lovi.care/skincare/fr/p/byoma/clarifying-serum/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/byoma/clarifying-serum/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/byoma/clarifying-serum/for/mature-skin (this page)
- Spain: https://lovi.care/skincare/es/p/byoma/clarifying-serum/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/byoma/clarifying-serum/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/byoma/clarifying-serum/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/byoma/clarifying-serum/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/byoma/clarifying-serum/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/byoma/clarifying-serum/for/mature-skin