Biossance Squalane + Amino Aloe Gentle Cleanser for acne-prone skin

How to apply

Questions and answers

What the research says

• Sodium cocoyl isethionate micelles are too large to penetrate stratum corneum aqueous pores, resulting in significant steric hindrance that prevents skin barrier perturbation and explains its skin mildness.

  Journal of Cosmetic Science, 2007

• A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.

  Clinical Pharmacology, 2018

• Moringa oleifera leaf extracts provided significant UV protection with an SPF of 2 at 2% to 4% concentrations and showed no significant irritant potential in cosmetic formulations.

  Molecules, 2018

• Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts.

  Molecules, 2025

• Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway.

  Antioxidants, 2025

• Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief.

  Plastic and Reconstructive Surgery, 2018

• Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo.

  Journal of Alternative and Complementary Medicine, 2010

• Formulations containing 0.10%, 0.25%, and 0.50% freeze-dried Aloe vera extract increased stratum corneum water content compared with the vehicle in 20 female subjects, while transepidermal water loss was not modified.

  Skin Research and Technology, 2006

• A topical formulation containing retinol, pea peptide, and antioxidants significantly improved hydration, transepidermal water loss, elasticity, and nine other skin parameters without irritation in 30 adult subjects over 8 weeks compared to baseline.

  Dermatology and Therapy, 2025

• Plant protein-based electrospun fiber scaffolds and patches derived from zein, soy, wheat gluten, and pea protein support cell adhesion, promote angiogenesis, and facilitate extracellular matrix remodeling to accelerate skin regeneration and wound healing.

  Macromolecular Rapid Communications, 2025

• Aqueous standardized leaf extracts of Moringa oleifera showed the highest human dermal fibroblast and human keratinocyte proliferation and migration properties, leading to the development of an alginate-pectin film dressing with optimal physicochemical properties.

  Journal of Ethnopharmacology, 2018

• Topical administration of Moringa oleifera seed extract on excision wounds in male albino rabbits significantly increased the wound healing rate, elevated TGF-β1, VEGF, and Type I collagen relative expression, and reduced inflammatory markers like IL-1β and TNF-α compared to untreated and MEBO-treated groups.

  Antioxidants, 2022

• Encapsulating Moringa oleifera Lam. isothiocyanate in flexible nanoliposomes modified with amphiphilic hyaluronic acid conjugated with ceramide improved entrapment efficiency, particle size, skin permeation, and cellular uptake while protecting HaCaT cells against UVB-induced photoaging damage.

  Drug Delivery, 2022

Ingredients

Water, Aloebarbadensis Leaf Juice, Cocamidopropyl Hydroxysultaine, Glycerin, Sodium Cocoyl Isethionate, Disodium Coco-Glucoside Citrate, Squalane, Cocoyl Proline, Moringa Oleifera Leaf Extract, Rosamarinus Officinalis Oil Leaf Rosemary Oil Leaf, Cymbopogon Schoenanthus Oil, Pelargonium Graveolens Oil, Salvia Sclarea Oil, Hydrolyzed Pea Protein, Medicago Sativa Extract, Sodium Levulinate, Caramel, Magnesium Chloride, Potassium Sorbate, Sodium Gluconate, Citric Acid, Citral, Citronellol, Linalool

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.