BIOHEAL BOH Probioderm Lifting Cream for mature skin
Peptides
Sodium Hyaluronate
Collagen
Retinol
Vitamin EAverage
- HighNormal Skin Fit
- HighEffectiveness
- HighSafety
Works for mature skin; other moisturizers fit it better.
This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers moderate benefits for your normal skin, as peptides and niacinamide support collagen production and barrier function to address wrinkles and fine lines.
- The formula also includes ingredients like tocopherol and rutin, which provide antioxidant protection and can help improve skin elasticity.
- The product is safe for your skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.
How to apply
- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
People Say
★4.8Overall rating based on 300+ reviewsThis rich cream is highly praised for its intense hydration and luxurious texture, making it ideal for dry and mature skin types. Many users report a plumping effect and improved skin elasticity, with some experiencing a noticeable lifting of sagging contours. However, the heavy formula can be too occlusive for oily skin, and the strong fragrance is a concern for some.
Highlights
Intense hydration Mostly Mentioned
- “healed flakiness on nose”
- “skin stays plump until morning”
- “perfect for winter skincare”
- “deeply nourishing feel”
Luxurious texture Often Mentioned
- “velvet veil finish”
- “absorbs beautifully”
- “rich but not sticky”
- “melts into skin”
Firming effect Sometimes Noted
- “jawline looks slightly more lifted”
- “skin feels tighter”
- “pores look smaller”
- “bouncier texture”
Good ingredients Sometimes Noted
- “love the peptide complex”
- “strengthens skin barrier”
- “great for barrier repair”
- “contains ceramides”
Strong fragrance Sometimes Noted
- “fragrance was slightly strong”
- “sensitive skin itched”
- “wish it was fragrance-free”
- “smell is overpowering”
Too heavy Sometimes Noted
- “too heavy for morning”
- “left an oily feel”
- “caused breakouts on forehead”
- “shiny finish”
Bulky packaging Rarely Noted
- “packaging seems oversized”
- “jar is huge for 50ml”
- “takes up too much space”
High price Rarely Noted
- “pricey without discount”
- “wait for Olive Young sale”
- “expensive for the amount”
Sources: lovi.care, global.oliveyoung.com, gopicky.com, reddit.com, yesstyle.com, and more
Questions and answers
How well does BIOHEAL BOH Probioderm Lifting Cream work for mature skin?
This cream works moderately well for mature skin, as its peptides and niacinamide help smooth fine lines and support firmness. To fit mature skin even better, a moisturizing treatment needs a richer blend of targeted anti-aging ingredients and deep hydrators like sodium hyaluronate and snail mucin to improve skin density and elasticity.
International Journal of Molecular Medicine, 2016Dermatology Practical & Conceptual, 2022
Which ingredients make this cream a good fit for mature skin?
This cream works for mature skin because its peptides and niacinamide support collagen production and barrier function, while tocopherol and rutin provide antioxidant protection and elasticity. To fit this skin type even better, a moisturizing treatment needs ingredients like snail mucin and sodium hyaluronate to deeply enhance hydration alongside these anti-aging components.
International Journal of Molecular Medicine, 2016Journal of Cosmetic Dermatology, 2021
What do Peptides do for mature skin?
Peptides help mature skin by signaling skin cells to boost collagen production, which improves firmness and smooths out fine lines. They are generally safe to use daily, though their ability to deliver results depends heavily on how well the formula can sink into the skin.
International Journal of Cosmetic Science, 2009Biomolecules, 2025
What does Hyaluronic Acid do for mature skin?
Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Journal of Drugs in Dermatology, 2011Skin Research and Technology, 2024
Where does this cream go in a skincare routine for mature skin?
This cream goes in your evening routine as a moisturizing treatment after cleansing and before your final moisturizer. A mature skin cream of this type needs collagen-boosting peptides, nourishing hydrators like sodium hyaluronate, and firming ingredients such as retinol to properly address fine lines and loss of elasticity.
Journal of Drugs in Dermatology, 2023Journal of Drugs in Dermatology, 2025
Can I use this cream with vitamin C, and in what order?
How often should I use this cream?
This cream works well when applied twice a day as part of your daily routine to help keep mature skin hydrated and smooth. Regular daily use of this type of moisturizer supports skin elasticity and helps address fine lines over time.
Journal of Cosmetic Dermatology, 2020Health Science Reports, 2021
Can this cream clog pores, cause breakouts or purging for mature skin?
This cream is unlikely to clog pores or cause breakouts for mature skin since it avoids harsh ingredients, though it may feel a bit heavy. Mature skin dealing with heavy textures often benefits from lighter, non-greasy formulas containing hyaluronic acid, niacinamide, and antioxidants to smooth fine lines without feeling overly thick.
Can I use this cream around the eyes or on my body?
You can use this moisturizing treatment around your eyes and on your body, as its gentle formula is safe and unlikely to cause irritation. To properly care for mature skin in these areas, a product of this type needs firming ingredients like peptides and retinol, along with deep hydrators like hyaluronic acid and collagen to keep skin smooth.
Surgical and Radiologic Anatomy, 2002Journal of Biomedical Research, 2017
Is this cream fragrance-free and alcohol-free?
Yes, it has no fragrance and no drying alcohol.
What the research says
Both oral and topical collagen supplements help delay the skin aging process by improving moisture, elasticity, and hydration, with no differences arising between the two types of collagen.
Dermatology Practical & Conceptual, 2022The use of cosmetic products containing collagen or its peptides improves the general condition of the skin, reduces wrinkle depth, improves hydration and density, reduces transepithelial water loss, and delays the aging process, while oral bioactive collagen peptides also reduce nail breakage.
Current Issues in Molecular Biology, 2024Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.
Journal of Cosmetic Dermatology, 2021Rutin application increased skin elasticity and decreased wrinkle length, area, and number in 40 human subjects compared to a control group over 4 weeks.
International Journal of Molecular Medicine, 2016A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers.
Journal of Cosmetic Dermatology, 2020Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris.
Journal of Cosmetic Dermatology, 2022Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks.
International Journal of Molecular Sciences, 2022Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers.
Marine Drugs, 2023Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle.
International Journal of Cosmetic Science, 2017Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging.
The British Journal of Dermatology, 2019Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity.
Journal of Controlled Release, 2018Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls.
Journal of Cosmetic Dermatology, 2025Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.
Contemporary Clinical Trials Communications, 2021Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin.
Journal of Cosmetic Dermatology, 2024
Ingredients
Water, Lactobacillus Ferment, Dipropylene Glycol, Glycerin, Caprylic Capric Triglyceride, Hydrogenated Poly C6-14 Olefin, Hydrogenated Polydecene, Glyceryl Stearate Se, 12-Hexanediol, Hydrogenated Oil, Niacinamide, Tocopheryl Acetate, Tocopherol, Rutin, Copper Tripeptide-1, Lecithin, Oleic Acid, Olea Europaea Oil Olive Oil, Jojoba Esters, Sucrose, Curcuma Longa Root Extract, Dipotassium Glycyrrhizate, Ceramide Np, Peptides
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
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Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
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Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
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Medical Board
Cosmetic chemist, SCS, IFSCC member
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Medical Board, Medical Advisor
Dermatology MD
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Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
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Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
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