# Bioderma Pigmentbio Sensitive Areas for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/nl/p/bioderma/pigmentbio-sensitive-areas/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Bioderma](https://lovi.care/skincare/nl/brands/bioderma)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate exfoliation for your acne and blemishes due to the presence of salicylic acid and azelaic acid, which help to unclog pores and reduce inflammation.
- The formula is highly suitable for your combination skin, as these ingredients also regulate melanogenesis to even skin tone.
- The product is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/bioderma/pigmentbio-sensitive-areas/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/nl/p/bioderma/pigmentbio-sensitive-areas/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/nl/p/bioderma/pigmentbio-sensitive-areas/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/nl/p/bioderma/pigmentbio-sensitive-areas/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/nl/p/bioderma/pigmentbio-sensitive-areas/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/nl/p/bioderma/pigmentbio-sensitive-areas/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/nl/p/bioderma/pigmentbio-sensitive-areas/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/bioderma/pigmentbio-sensitive-areas/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/bioderma/pigmentbio-sensitive-areas/for/oily-acne-prone-skin): High

## Key ingredients

Azelaic Acid, Licorice Root Extract, Salicylic Acid, Andrographis Paniculata Leaf Extract, Laminaria Ochroleuca Extract

## What the research says

- Azelaic acid nanocrystal hydrogel 10% achieved a higher success rate and greater lesion reduction than azelaic acid cream 20% in patients with mild to moderate facial acne. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/))
- Application of 15% azelaic acid gel significantly reduced post-inflammatory erythema and hyperpigmentation, decreased hemoglobin and melanin content, improved quality of life, and contributed to acne improvement in patients with mild to moderate acne compared to placebo. ([Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Combined treatment of andrographolide and Bidens pilosa extract activated RXR alpha, enhanced extracellular matrix protein gene expression with antioxidant and anti-inflammatory efficacies, and improved wrinkles, skin elasticity, and hydration without causing irritating side effects in human subjects. ([Biomolecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40001599/))
- Topical application of a dermocosmetic containing Myrtus communis extract and azelaic acid reduced acne relapses and helped maintain remission compared to a light moisturizing cream in adult females in the acne maintenance phase over 16 weeks. ([Journal of the European Academy of Dermatology and Venereology, 2023](https://pubmed.ncbi.nlm.nih.gov/36729399/))
- Topical administration of 20% azelaic acid cream and 5% tranexamic acid solution comparably improved acne-related postinflammatory hyperpigmentation in patients with acne vulgaris, while tranexamic acid demonstrated a significantly better safety profile at week 4. ([Journal of Research in Medical Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/37213446/))
- Azelaic acid 15% gel showed comparable efficacy to adapalene 0.1% gel in reducing lesions, severity, and Dermatology Life Quality Index in women with adult acne, with significantly lower dryness and scaling, and demonstrated superiority during maintenance compared to no further treatment. ([Journal of the European Academy of Dermatology and Venereology, 2015](https://pubmed.ncbi.nlm.nih.gov/25399481/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Cryotherapy with liquid nitrogen achieved a higher cure rate (39%) than salicylic acid (24%) and a wait-and-see approach (16%) for cutaneous warts at 13 weeks in primary care patients. ([CMAJ, 2010](https://pubmed.ncbi.nlm.nih.gov/20837684/))
- Treatment with 2% supramolecular salicylic acid hydrogel resulted in a regression and markedly improvement rate of 51.01% compared to 43.10% for Adapaline gel in patients with mild to moderate facial acne vulgaris, showing no significant difference in efficacy. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590107/))
- Topical 5% benzoyl peroxide plus salicylic acid achieved the greatest lesion reduction at early 2 to 4 week time points compared to benzoyl peroxide, clindamycin, and combination benzoyl peroxide/clindamycin, while 5% benzoyl peroxide plus salicylic acid and combination benzoyl peroxide/clindamycin showed similar efficacy at 10 to 12 weeks in acne patients. ([Journal of the American Academy of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20488582/))
- An Andrographis paniculata extract promoted epidermal stem cell proliferation, up-regulated integrin beta1 and vascular endothelial growth factor expression, enhanced collagen production, and improved skin hydration, dermal density, wrinkling, and sagging in clinical evaluation. ([Molecules, 2015](https://pubmed.ncbi.nlm.nih.gov/26402665/))
- Topical administration of andrographolide sodium bisulfate prevented UV-induced skin photoaging in mice by increasing collagen content, reducing epidermal thickness and MDA levels, upregulating SOD and CAT activities, and downregulating IL-1β, IL-6, IL-10, and TNF-α production compared to UV-irradiated mice without ASB. ([Mediators of Inflammation, 2016](https://pubmed.ncbi.nlm.nih.gov/26903706/))
- Matrine, baicalin, ursolic acid, sodium danshensu, magnolol, honokiol, hesperidin, and andrographolide significantly reduced IL-8 and TNF-alpha production in human HaCaT keratinocytes pretreated with heat-killed Propionibacterium acnes. ([Natural Product Research, 2012](https://pubmed.ncbi.nlm.nih.gov/21999396/))

## What reviewers say

Based on limited data, this product is highly praised for its ability to gently fade hyperpigmentation and dark spots in delicate areas. Users with sensitive skin appreciate its soothing, non-irritating, and hydrating formula, though some note that achieving visible lightening outcomes requires consistent, long-term application.

- Liked: Fades dark spots (often mentioned)
- Liked: Gentle on skin (often mentioned)
- Liked: Absorbs very quickly (sometimes noted)
- Liked: Hydrating and moisturizing (sometimes noted)
- Disliked: Slow visible results (sometimes noted)
- Disliked: Half empty tubes (rarely noted)
- Disliked: Poor packaging design (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Bioderma Pigmentbio Sensitive Areas work for acne-prone skin?

This treatment works moderately well for acne-prone skin, as it contains salicylic acid and azelaic acid to unclog pores and help reduce blemishes without irritating. To fit this skin type best, a treatment needs ingredients like niacinamide, propolis, or zinc PCA that balance oil and hydration while keeping skin clear.
Sources: [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/), [Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/)

### Which ingredients make this cream a good fit for acne-prone skin?

This cream works for acne-prone skin because salicylic acid and azelaic acid provide moderate exfoliation that helps to unclog pores and reduce inflammation. To fit this skin type even better, products need ingredients like niacinamide, zinc PCA, or propolis that balance oil and hydrate without causing excess oiliness or dryness.
Sources: [BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/)

### What does Azelaic Acid do for acne-prone skin?

Azelaic acid helps clear acne-prone skin by fighting bacteria and calming redness, while also fading dark spots left behind by breakouts. It targets multiple causes of acne at once to keep your skin smooth and even-toned.
Sources: [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26355614/), [Postepy Dermatologii I Alergologii, 2023](https://pubmed.ncbi.nlm.nih.gov/38282869/)

### What does Licorice Root Extract do for acne-prone skin?

Licorice Root Extract helps calm red, irritated skin and soothe breakouts. It also works to fade the dark marks that pimples often leave behind.
Sources: [The Journal of Dermatological Treatment, 2003](https://pubmed.ncbi.nlm.nih.gov/14522625/)

### Where does this cream go in a skincare routine for acne-prone skin?

This treatment goes in the evening routine after cleansing, and products for this skin need exfoliating acids like salicylic acid or azelaic acid to help clear pores and reduce blemishes.

### Can I use this cream with retinol, and in what order?

You can use this treatment alongside a retinol, applying the treatment in your PM routine after cleansing and toning, and before your moisturizer. Because this product already contains exfoliating ingredients like salicylic acid and azelaic acid, combining it with retinol may increase skin sensitivity, so it is best to introduce them slowly. An acne-prone skin routine works best when it includes gentle soothing ingredients and barrier-repairing agents to prevent dryness and irritation.

### How often should I use this cream?

You can use this treatment in your evening routine once a week to start, and then slowly use it more often if your skin tolerates it well. A product of this type needs soothing ingredients and gentle exfoliants that unclog pores without causing irritation.
Sources: [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/), [Dermatology and Therapy, 2024](https://pubmed.ncbi.nlm.nih.gov/38734843/)

### Can this cream clog pores, cause breakouts or purging for acne-prone skin?

This cream is unlikely to clog pores or cause breakouts because it contains salicylic acid and azelaic acid, which help to unclog pores and reduce inflammation. However, because this is an average fit for acne-prone skin, a product of this type needs more targeted oil-controlling ingredients and lightweight hydrators to fully prevent breakouts.
Sources: [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/nl/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — €10.20 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/nl/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — €35.80 at Amazon
- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/nl/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/acne-prone-skin) — Superior fit — €99.41 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/nl/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.99 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — €19.90 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — €19.20 at Amazon

## Where to buy

- Amazon.nl: €39.46 (https://www.amazon.nl/dp/B09231D8X3?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- Notino: €39.70 (https://www.notino.nl/bioderma/pigmentbio-sensitive-areas-whitening-creme-voor-het-gezicht-en-gevoelige-plekjes/p-16277872/)
Prices checked 16 Oct – 4 Nov 2026.

## Ingredients

Water, Glycerin, Cetyl Alcohol, Dimethicone, Polymethylsilsesquioxane, Dipropylene Glycol, Propylheptyl Caprylate, Caprylic Capric Triglyceride, Hdi Trimethylol Hexyllactone Crosspolymer, C14-22 Alcohols, Pentylene Glycol, Carbomer, Polysilicone-11, Caprylyl Glycol, 1,2-Hexanediol, Ammonium Acryloyldimethyltaurate Vp Copolymer, Butylene Glycol, Disodium Edta, Lysine, C12-20 Alkyl Glucoside, Azelaic Acid, Laminaria Ochroleuca Extract, Mannitol, Salicylic Acid, Xylitol, Andrographis Paniculata Leaf Extract, Rhamnose, Sodium Hydroxide, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Decyl Glucoside, Fructooligosaccharides, Tocopherol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/bioderma/pigmentbio-sensitive-areas/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/bioderma/pigmentbio-sensitive-areas/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/bioderma/pigmentbio-sensitive-areas/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/bioderma/pigmentbio-sensitive-areas/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/bioderma/pigmentbio-sensitive-areas/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/bioderma/pigmentbio-sensitive-areas/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/bioderma/pigmentbio-sensitive-areas/for/acne-prone-skin (this page)
- Spain: https://lovi.care/skincare/es/p/bioderma/pigmentbio-sensitive-areas/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/bioderma/pigmentbio-sensitive-areas/for/acne-prone-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/bioderma/pigmentbio-sensitive-areas/for/acne-prone-skin