# ATOPALM MLE Cream for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/nl/p/atopalm/mle-cream/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [ATOPALM](https://lovi.care/skincare/nl/brands/atopalm)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/nl/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for combination skin; a few moisturizers fit it even better.

## Why this fit

- This product offers excellent moisturizing for your combination skin, with glycerin and shea butter providing hydration and enhancing barrier resilience to help manage oily shine.
- Squalane and sodium hyaluronate further support humectant and emollient actions, beneficial for maintaining balanced hydration without exacerbating oiliness.
- The formula is safe for your combination skin, as it lacks harsh ingredients and is unlikely to cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/atopalm/mle-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/nl/p/atopalm/mle-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/nl/p/atopalm/mle-cream/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/nl/p/atopalm/mle-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/nl/p/atopalm/mle-cream/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/nl/p/atopalm/mle-cream/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/nl/p/atopalm/mle-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/atopalm/mle-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/atopalm/mle-cream/for/oily-acne-prone-skin): High

## Key ingredients

Mle Multi-Lamellar Emulsion Technology, Butyrospermum Parkii Butter Shea Butter, Squalane, Jojoba Seed Oil, Sodium Hyaluronate

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Atopalm MLE Cream and Physiogel Intensive Cream both significantly increased stratum corneum hydration and improved lactic acid stinging test scores after 4 weeks in 60 patients with sensitive skin, while Atopalm MLE Cream also significantly lowered transepidermal water loss at 2 and 4 weeks. ([Dermatology and Therapy, 2016](https://pubmed.ncbi.nlm.nih.gov/26841947/))
- Multi-lamellar emulsion (MLE) as a vehicle for topical desonide increased epidermal retention and partially prevented steroid-induced skin barrier impairment without reducing the anti-inflammatory activity in murine models. ([Annals of Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23467730/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Clay jojoba oil facial masks reduced total skin lesions by a mean of 54% after 6 weeks in 133 participants with acne-prone, lesioned skin and mild acne compared to baseline. ([Forschende Komplementarmedizin, 2012](https://pubmed.ncbi.nlm.nih.gov/22585103/))
- Topical application of jojoba wax reduced LPS-induced secretion of IL-6, IL-8, and TNFα by approximately 30% and increased the synthesis of pro-collagen III and hyaluronic acid compared to untreated skin in an ex-vivo human skin organ culture model. ([Frontiers in Pharmacology, 2024](https://pubmed.ncbi.nlm.nih.gov/38344180/))
- Topical jojoba oil application in male mice decreased exercise-induced pro-inflammatory gene expression (Il-1b and Il-6 in soleus, Il-1b in gastrocnemius) compared to untreated exercised mice. ([Biomolecules, 2025](https://pubmed.ncbi.nlm.nih.gov/41154623/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## What reviewers say

Users frequently experience improvements in skin texture, reduced redness, and relief from itchiness, making it a favored product for adults and babies alike. Some users find the jar packaging unhygienic and a few note that it can be too heavy for facial use or is priced high.

- Liked: Deeply moisturizing (mostly mentioned)
- Liked: Absorbs quickly (often mentioned)
- Liked: Gentle on skin (often mentioned)
- Liked: Repairs skin barrier (often mentioned)
- Disliked: Jar packaging (sometimes noted)
- Disliked: High price (rarely noted)
- Disliked: Too heavy (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Atopalm MLE Cream a great fit for combination skin?

Atopalm MLE Cream is a great fit because glycerin and shea butter provide hydration and strengthen your skin barrier to help manage oily shine. Squalane and sodium hyaluronate maintain balanced hydration without making your skin more oily, and the formula is unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for combination skin?

Glycerin and shea butter provide hydration and strengthen your skin barrier to help manage oily shine, while squalane and sodium hyaluronate maintain balanced moisture without feeling heavy. The formula also has a very safe profile and is unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Multi-Lamellar Emulsion do for combination skin?

Multi-lamellar emulsion helps keep combination skin balanced by locking in moisture without feeling heavy, while supporting the skin barrier. Creams of this type for combination skin need lightweight hydrators and skin-identical lipids that nourish dry areas while staying comfortable on oily zones.
Sources: [Dermatology and Therapy, 2016](https://pubmed.ncbi.nlm.nih.gov/26841947/), [International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/39113294/)

### What does Butyrospermum Parkii Butter do for combination skin?

Butyrospermum parkii butter helps keep combination skin soft and smooth while supporting the skin barrier. This ingredient is generally well tolerated, though a product for this skin type also needs lightweight hydration to balance oilier zones without clogging pores.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32385930/), [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/28707186/)

### Where does this cream go in a skincare routine for combination skin?

This cream goes after your hydrating toner in the morning and after your treatment in the evening, as part of your daily routine. It helps lock in moisture and keeps your combination skin balanced without feeling heavy or greasy.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying it either before or after your retinol treatment to help keep your skin comfortable and hydrated. Using a barrier-supporting moisturizer alongside active treatments like retinoids is unlikely to cause irritation and may improve how well your skin adjusts to the routine.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22648223/)

### How often should I use this cream?

You can use this moisturizer twice a day, morning and evening, as part of your regular skincare routine. Daily application helps maintain balanced hydration and supports your skin barrier without causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for combination skin?

This cream is unlikely to cause irritation or breakouts on combination skin because it lacks harsh ingredients and uses barrier-supporting ingredients to maintain balanced hydration without clogging pores. Its formula is well-suited to keep your skin calm and smooth.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream around the eyes or on my body?

You can use this cream safely around your eyes and on your body because its gentle formula provides excellent moisture without causing irritation. Ingredients like squalane, shea butter, and sodium hyaluronate help keep delicate areas smooth and well-hydrated.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for combination skin

- [The Ordinary Natural Moisturizing Factors + HA](https://lovi.care/skincare/nl/p/the-ordinary/natural-moisturizing-factors-ha/for/combination-skin) — High fit — €13.02 at Amazon
- [Anua Heartleaf 78% Soothing Cream](https://lovi.care/skincare/nl/p/anua/heartleaf-78-soothing-cream/for/combination-skin) — High fit — €25.29 at Amazon
- [ANUA Heartleaf 70% Soothing Cream](https://lovi.care/skincare/nl/p/anua/heartleaf-70-soothing-cream/for/combination-skin) — High fit — €25.29 at Amazon

## Pairs well with

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/nl/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — €16.50 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — €36.00 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — €33.70 at Amazon

## Where to buy

No store in Netherlands has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Caprylic Capric Triglyceride, Cetearyl Alcohol, Pentaerythrityl Stearate Caprate Caprylate Adipate, Pentylene Glycol, Butyrospermum Parkii Butter Shea Butter, Propanediol, Sorbitan Stearate, Stearic Acid, Squalane, Polyglyceryl-5 Stearate, Jojoba Seed Oil, Glyceryl Stearate, Palmitoyl Palmitamide Mea, N-Decanoyl Serinol, Bis-Capryloyloxypalmitamido Isopropanol, Allantoin, Houttuynia Cordata Extract, Leucine, Lysine, Valine, Threonine, Phenylalanine, Hydrogenated Oil, Olea Europaea Oil Fruit Olive Oil Fruit, Tocopherol, Carbomer, Phytosterols, Phytosteryl Oleate, Carthamus Tinctorius Seed Oil, Vitis Vinifera Seed Oil Grape Seed Oil, Sodium Phytate, Arginine, Portulaca Oleracea Extract, Xanthan Gum, Helianthus Annuus Seed Oil Sunflower Seed Oil, Mistletoe Fruit Extract, Camellia Sinensis Seed Oil, Sodium Hyaluronate, Sunflower Decyl Esters Oil, Salvia Officinalis Oil, Beta-Glucan, Elettaria Cardamomum Seed Oil, Pogostemon Cablin Oil, Juniperus Mexicana Oil, Juniperus Communis Oil Fruit, Anthemis Nobilis Oil Flower, Butylene Glycol, 1,2-Hexanediol, Caprylic Capric Glycerides
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/atopalm/mle-cream/for/combination-skin
- United Kingdom: https://lovi.care/skincare/uk/p/atopalm/mle-cream/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/atopalm/mle-cream/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/atopalm/mle-cream/for/combination-skin
- France: https://lovi.care/skincare/fr/p/atopalm/mle-cream/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/atopalm/mle-cream/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/atopalm/mle-cream/for/combination-skin (this page)
- Spain: https://lovi.care/skincare/es/p/atopalm/mle-cream/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/atopalm/mle-cream/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/atopalm/mle-cream/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/atopalm/mle-cream/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/atopalm/mle-cream/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/atopalm/mle-cream/for/combination-skin