# Anua Heartleaf 77% Clear Pad for acne-prone skin

**Lovi Fit: High fit for acne-prone skin.**
Combination Skin Fit: Superior · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/nl/p/anua/heartleaf-77-clear-pad/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Anua](https://lovi.care/skincare/nl/brands/anua)
Category: [Toners](https://lovi.care/skincare/nl/best/toners)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for acne-prone skin; a few toners fit it even better.

## Why this fit

- Excellent suitability for your combination skin is provided by Houttuynia Cordata Extract and Gluconolactone, which offer anti-inflammatory and gentle exfoliating actions respectively, addressing your acne and breakouts.
- The high concentration of Houttuynia Cordata Extract and Centella Asiatica Extract ensures effective soothing and calming of irritated skin, further supporting your skin's needs.
- The product is safe for your skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/anua/heartleaf-77-clear-pad/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/nl/p/anua/heartleaf-77-clear-pad/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/nl/p/anua/heartleaf-77-clear-pad/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/nl/p/anua/heartleaf-77-clear-pad/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/nl/p/anua/heartleaf-77-clear-pad/for/acne-prone-skin): High (this page)
- [Skin with dark spots](https://lovi.care/skincare/nl/p/anua/heartleaf-77-clear-pad/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/nl/p/anua/heartleaf-77-clear-pad/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/anua/heartleaf-77-clear-pad/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/anua/heartleaf-77-clear-pad/for/oily-acne-prone-skin): High

## Key ingredients

Houttuynia Cordata Extract, Centella Asiatica Extract, Madecassoside, Oenothera Biennis Flower Extract, Betaine

## What the research says

- Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients. ([The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/))
- Glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene showed no hindrance compared to adapalene monotherapy and provided benefits in reducing complications in 25 subjects with mild-to-moderate acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30858720/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Soaps containing betaine caused the least skin irritation compared to other tested soaps in twenty-eight healthy subjects, though irritation did not decrease with increasing concentrations of betaine. ([Skin Research and Technology, 2003](https://pubmed.ncbi.nlm.nih.gov/12535284/))
- Quercetin phospholipids 1% cream significantly reduced UV-, histamine-, and chemical-induced skin erythema (-10.05%) and mean wheal diameter in 30 healthy human volunteers, showing comparable efficacy to 1% dexchlorpheniramine cream. ([Clinical, Cosmetic and Investigational Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27013898/))
- Quercetin-loaded niosomes formulated with Span60-RH40 at a 9:11 mass ratio improved quercetin solubility, photostability, sustained release, and transdermal penetration, yielding a skin retention 2.95 times higher than quercetin solution. ([Molecules, 2019](https://pubmed.ncbi.nlm.nih.gov/31238562/))
- Optimized rutin-loaded glycerosomes formulated into a nanosunscreen gel demonstrated sustained drug release, greater skin permeation, good antioxidant activity, and better epidermal retention compared to the dermis, indicating high safety, stability, and sun protection factor values for topical administration. ([Gels, 2023](https://pubmed.ncbi.nlm.nih.gov/37754433/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Electrospun poly (vinyl butyral-co-vinyl alcohol-co-vinyl acetate) patches loaded with evening primrose oil applied to the forearm of volunteers for 6 hours increased skin moisture, with pore size, shape, and fiber diameter influencing oil transport. ([Biomaterials Advances, 2022](https://pubmed.ncbi.nlm.nih.gov/35929319/))
- A topical preparation containing urea, sunflower oil, evening primrose oil, wheat germ oil, and sodium pyruvate led to clinical improvement after a month in diverse hyperkeratotic skin conditions except pityriasis lichenoides. ([Medicina Cutanea Ibero-latino-americana, 1986](https://pubmed.ncbi.nlm.nih.gov/3528709/))
- Oenothera biennis cell culture aqueous extract promoted matrix collagen contraction, actin polymerization, and essential extracellular matrix protein production by increasing MYLK gene expression in in vitro, cell, and ex vivo skin aging models. ([Metabolites, 2021](https://pubmed.ncbi.nlm.nih.gov/34436468/))
- Topical dry mouth products containing olive oil, betaine, and xylitol significantly increased unstimulated whole salivary flow rates, reduced xerostomia complaints, and improved quality of life in adults with polypharmacy-induced xerostomia compared to their normal routine care, with no clinically significant adverse events. ([Journal of Oral Rehabilitation, 2007](https://pubmed.ncbi.nlm.nih.gov/17824884/))
- A combination of Aloe barbadensis leaf extract and trimethylglycine in a 1:1 mass ratio synergistically increased aquaporin 3 expression by up to 380% in keratinocytes and safely improved skin hydration in healthy volunteers. ([Molecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38611819/))
- Mixed surfactant systems of sodium dodecyl sulfate and dimethyl dodecyl amido betaine significantly reduce acute skin irritation potential in human volunteers compared with the individual surfactants, demonstrating that irritation potential cannot be predicted by simple summation. ([Food and Chemical Toxicology, 1998](https://pubmed.ncbi.nlm.nih.gov/9609395/))

## What reviewers say

Based on a very large amount of data, users with sensitive, acne-prone, and combination skin frequently praise these pads for their ability to gently exfoliate and calm redness without stripping moisture. While many report smoother texture and reduced breakouts, a minority of users experienced sticky residue or skin purging that led to worsening acne.

- Liked: Soothing and calming (mostly mentioned)
- Liked: Gentle exfoliation (often mentioned)
- Liked: Hydrating finish (often mentioned)
- Liked: Hygienic packaging (sometimes noted)
- Liked: Improves skin texture (sometimes noted)
- Disliked: Caused breakouts (sometimes noted)
- Disliked: Ineffective for some (rarely noted)
- Disliked: Not for dry skin (rarely noted)
- Disliked: Sticky residue (rarely noted)

## How to apply

- Use your soothing toner AM and PM daily to help keep breakouts under control.
- Apply this soothing toner right after cleansing and before your moisturizer or SPF.
- Gently press 2-3 drops of the soothing toner into your skin and let it absorb.
- Pat the soothing toner onto clean, slightly damp skin for the best absorption.
- Always do a patch test before first use and avoid getting the soothing toner in your eyes.
- Video: https://storage.pora.ai/25abe7eb181ba53153fd15de2058c2a9.mp4

## Questions and answers

### What makes ANUA Heartleaf 77% Clear Pad a great fit for acne-prone skin?

ANUA Heartleaf 77% Clear Pad is a great fit for acne-prone skin because it uses Houttuynia Cordata Extract and Centella Asiatica Extract to calm irritation, while gluconolactone provides gentle exfoliation to help clear breakouts. This formula has an excellent safety profile with no harsh ingredients, making it very unlikely to cause irritation.
Sources: [The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Which ingredients make this toner a good fit for acne-prone skin?

This toner is a great fit for your acne-prone skin thanks to Houttuynia Cordata extract and gluconolactone, which help calm redness and gently clear breakouts. It also includes centella asiatica extract to soothe irritated areas safely without harsh ingredients.
Sources: [The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Houttuynia Cordata Extract do for acne-prone skin?

Houttuynia cordata extract helps acne-prone skin by fighting bacteria and calming redness and swelling. It reduces cell damage from inflammation and supports skin repair, making it a soothing addition to your routine.
Sources: [Antioxidants, 2022](https://pubmed.ncbi.nlm.nih.gov/35204104/), [Heliyon, 2024](https://pubmed.ncbi.nlm.nih.gov/38420455/)

### What does Centella Asiatica Extract do for acne-prone skin?

Centella asiatica extract helps calm angry skin, reduces redness, and supports healing for breakouts. It is unlikely to cause irritation and may improve overall skin clarity when used consistently.
Sources: [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/), [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/)

### Where does this toner go in a skincare routine for acne-prone skin?

This soothing toner fits great into an acne-prone routine as a cleansing toner used in the evening after your cleanser and before your treatment. It helps calm irritated skin and clear breakouts safely without harsh ingredients.
Sources: [The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use this toner with retinol, and in what order?

You can use this soothing toner with retinol because it contains gentle ingredients that calm irritated skin and address breakouts without harsh risks. Apply the toner first on clean skin to help soothe your face, and follow with your retinol treatment once it absorbs.

### How often should I use this toner?

Start using this toner once a week to see how your acne-prone skin reacts, and carefully use it more often if you tolerate it well and see good results. It is a great fit because Houttuynia Cordata Extract and Gluconolactone help calm breakouts and gently exfoliate without harsh risks.
Sources: [The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can this toner clog pores, cause breakouts or purging for acne-prone skin?

This toner is a great fit for acne-prone skin because it uses Houttuynia Cordata Extract and gluconolactone to calm breakouts and gently exfoliate without harsh ingredients. While reviewers sometimes report breakouts, studies show these ingredients have a safe profile with very low risks of irritation.
Sources: [The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this toner fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Pyunkang Yul Calming Toner Pad](https://lovi.care/skincare/nl/p/pyunkang-yul/calming-toner-pad/for/acne-prone-skin) — Superior fit — €24.99 at Amazon
- [1004 Skin Madagascar Centella Toning Toner](https://lovi.care/skincare/nl/p/1004-skin/madagascar-centella-toning-toner/for/acne-prone-skin) — Superior fit — €17.96 at Amazon
- [Numbuzin No.1 Pure-Full Calming Herb Toner](https://lovi.care/skincare/nl/p/numbuzin/no-1-pure-full-calming-herb-toner/for/acne-prone-skin) — High fit — €17.50 at Amazon

## Pairs well with

- Cleanser: [B.LAB Matcha Hydrating Foam Cleanser](https://lovi.care/skincare/nl/p/b-lab/matcha-hydrating-foam-cleanser/for/acne-prone-skin) — Superior fit — €13.99 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/acne-prone-skin) — Superior fit — €19.20 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/nl/p/d-alba/piedmont-waterfull-mild-sunscreen/for/acne-prone-skin) — Superior fit — €16.75 at Amazon

## Where to buy

- Amazon.nl: €22.00 (https://www.amazon.nl/dp/B08JLMRTZS?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €20.24 (https://www.lookfantastic.nl/p/anua-heartleaf-77-clearpad-160ml/16201623/)
- Notino: €25.90 (https://www.notino.nl/anua/heartleaf-77-toner-pad-exfolierende-reiniging-pads-anti-blackheads/p-16242674/)
Prices checked 14 Oct – 5 Nov 2026.

## Ingredients

Houttuynia Cordata Extract, Water, Gluconolactone, Propanediol, Tromethamine, Butylene Glycol, 1,2-Hexanediol, Betaine, Ammonium Acryloyldimethyltaurate Vp Copolymer, Ulmus Davidiana Root Extract, Pueraria Lobata Root Extract, Pinus Palustris Leaf Extract, Oenothera Biennis Flower Extract, Camellia Sinensis Leaf Extract, Coix Lacryma-Jobi Seed Extract, Portulaca Oleracea Extract, Centella Asiatica Extract, Madecassoside, Asiatic Acid, Asiaticoside, Madecassic Acid, Sodium Phytate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/anua/heartleaf-77-clear-pad/for/acne-prone-skin
- United Kingdom: https://lovi.care/skincare/uk/p/anua/heartleaf-77-clear-pad/for/acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/anua/heartleaf-77-clear-pad/for/acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/anua/heartleaf-77-clear-pad/for/acne-prone-skin
- France: https://lovi.care/skincare/fr/p/anua/heartleaf-77-clear-pad/for/acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/anua/heartleaf-77-clear-pad/for/acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/anua/heartleaf-77-clear-pad/for/acne-prone-skin (this page)
- Spain: https://lovi.care/skincare/es/p/anua/heartleaf-77-clear-pad/for/acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/anua/heartleaf-77-clear-pad/for/acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/anua/heartleaf-77-clear-pad/for/acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/anua/heartleaf-77-clear-pad/for/acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/anua/heartleaf-77-clear-pad/for/acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/anua/heartleaf-77-clear-pad/for/acne-prone-skin