# Allies of Skin Tranexamic & Arbutin Advanced Brightening Serum for skin with dark spots

**Lovi Fit: High fit for skin with dark spots.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/nl/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/dark-spots

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Brand: [Allies of Skin](https://lovi.care/skincare/nl/brands/allies-of-skin)
Category: [Serums and treatments](https://lovi.care/skincare/nl/best/serums)

This fit is calculated for the concerns frequently associated with dark spots: hyperpigmentation, sun spots, and uneven skin tone. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best serums for skin with dark spots.

## Why this fit

- Highly suitable for your normal skin, this serum effectively targets pigmentation concerns with tranexamic acid and alpha-arbutin, which work to reduce dark spots and regulate melanogenesis. Niacinamide further supports barrier repair, enhancing overall skin health.
- The inclusion of Bisabolol and Panthenol provides soothing benefits, ensuring a comfortable experience for your normal skin.
- The product demonstrates a strong safety profile with no identified risks of irritation due to its gentle formulation and absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/nl/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/nl/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/nl/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/nl/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/nl/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/nl/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/dark-spots): High (this page)
- [Mature skin](https://lovi.care/skincare/nl/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/nl/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/nl/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Alpha Arbutin, Tranexamic Acid, Niacinamide, Mushroom Complex, 6 Brighteners, Peptides

## What the research says

- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Encapsulation of alpha arbutin in an optimized ethosomal gel significantly improved skin melanin reduction, moisture content, and elasticity in human volunteers compared to conventional formulations. ([Heliyon, 2023](https://pubmed.ncbi.nlm.nih.gov/37681127/))
- A non-hydroquinone topical formulation (SKNB19) improved hyperpigmentation by 28.5% in patient self-assessment and 27% in independent reviewer assessment compared with 4% hydroquinone in 18 adult subjects, while showing significantly less irritation and better tolerability. ([Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/33022197/))
- Combining a home-based radiofrequency device and arbutin cream reduced mMASI scores by 25.6% and melanin index by 22.8% at 8 weeks compared to baseline in 38 participants. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/39918262/))
- Polyvinyl pyrrolidone-K90/Eudragit RL100 dissolving microneedle patches loaded with alpha-arbutin and resveratrol enhanced intradermal delivery by approximately 2.6 times compared to cream and slightly decreased the melanin index in human participants without causing skin irritation. ([Biomaterials Science, 2023](https://pubmed.ncbi.nlm.nih.gov/37183632/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups. ([Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37171578/))
- Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment. ([The Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35570397/))

## What reviewers say

Users frequently report this serum effectively brightens skin and reduces hyperpigmentation like acne scars and melasma, with many appreciating its gentle, soothing, and lightweight formula suitable for sensitive skin. Some users find the price high and the results take longer than anticipated.

- Liked: Boosts radiance (often mentioned)
- Liked: Fades dark spots (often mentioned)
- Liked: Gentle and soothing (often mentioned)
- Liked: Lightweight texture (often mentioned)
- Disliked: High price point (often mentioned)
- Disliked: Slow results (sometimes noted)
- Disliked: Skin reactions (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Apply this serum as part of your PM routine starting 3x/week and build up to daily use if your skin likes it.
- Place the serum after cleansing and toning, but before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute for it to absorb.
- Apply the serum on dry skin to help fade pigmentation effectively.
- Avoid the eye area and always use SPF 30+ during the day.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Allies of Skin Tranexamic & Arbutin Advanced Brightening Serum a great fit for skin with dark spots?

This serum is a great fit for skin with dark spots because it combines tranexamic acid and alpha-arbutin to fade dark spots and even out skin tone. Niacinamide and soothing ingredients like bisabolol and panthenol help calm the skin and keep it comfortable with a very low risk of irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Which ingredients make this serum a good fit for skin with dark spots?

This serum is a great fit for skin with dark spots because it features tranexamic acid, alpha-arbutin, and niacinamide, which target dark spots and help fade pigmentation. These ingredients work together to lighten uneven areas while supporting overall skin health and comfort.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### What does Alpha Arbutin do for skin with dark spots?

Alpha arbutin helps fade dark spots by slowing down the enzyme that produces skin pigment, leading to a more even skin tone. It is unlikely to cause irritation and is generally well tolerated.
Sources: [Heliyon, 2023](https://pubmed.ncbi.nlm.nih.gov/37681127/)

### What does Tranexamic Acid do for skin with dark spots?

Tranexamic acid helps fade dark spots and uneven patches by slowing down the signals that trigger excess pigment in the skin. Studies show that using it regularly can significantly improve skin tone with a low risk of side effects.
Sources: [Clinical and Experimental Dermatology, 2016](https://pubmed.ncbi.nlm.nih.gov/27135282/), [Journal of Drugs in Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31741361/)

### Where does this serum go in a skincare routine for skin with dark spots?

This treatment serum goes in your evening routine after cleansing and toning, and before moisturizing. Putting treatments in the evening helps maintain extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

Yes, you can use this serum with retinol by applying the serum first in your routine and following it with your retinol product. This approach helps target dark spots while keeping your skin comfortable, as the gentle formulation is unlikely to cause irritation.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### How often should I use this serum?

This treatment serum works best in your evening routine, applied once a day. This gentle formulation has a very safe profile and is unlikely to cause irritation on normal skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Can this serum clog pores, cause breakouts or purging for skin with dark spots?

This serum is unlikely to cause breakouts or clog pores on skin with dark spots because it has a gentle formula without harsh ingredients. It brings a very low chance of skin reactions, making it comfortable for everyday use.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for skin with dark spots

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/nl/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dark-spots) — High fit — €10.20 at Amazon
- [Clinique Fresh Pressed Daily Booster with Pure Vitamin C 10%](https://lovi.care/skincare/nl/p/clinique/fresh-pressed-daily-booster-with-pure-vitamin-c-10/for/dark-spots) — High fit — €99.41 at Amazon
- [Guerlain Abeille Royale Double R Renew & Repair Serum](https://lovi.care/skincare/nl/p/guerlain/abeille-royale-double-r-renew-and-repair-advanced-serum/for/dark-spots) — High fit — €203.88 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/nl/p/cerave/foaming-facial-cleanser/for/dark-spots) — Superior fit — €21.00 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/nl/p/pyunkang-yul/calming-deep-moisture-toner/for/dark-spots) — Superior fit — €14.31 at Amazon
- Moisturizer: [SKIN1004 Centella Cream](https://lovi.care/skincare/nl/p/skin1004/centella-cream/for/dark-spots) — Superior fit — €19.20 at Amazon

## Where to buy

- Notino: €95.50 (https://www.notino.nl/allies-of-skin/tranexamic-arbutin-advanced-verhelderende-serum-tegen-oneffenheden/p-16290575/)
- Lookfantastic: €106.95 (https://www.lookfantastic.nl/p/allies-of-skin-tranexamic-arbutin-advanced-brightening-serum/15943021/)
Prices checked 10 Oct 2026.

## Ingredients

Water, Niacinamide, Ganoderma Lucidum Extract Ferment Filtrate Lentinus Edodes Extract Ferment Filtrate, C13-15 Alkane, Tranexamic Acid, Glycerin, Alpha-Arbutin, Pentylene Glycol, Butylene Glycol, Tocopheryl Acetate, Palmaria Palmata Extract, Asparagopsis Armata Extract, Helianthus Annuus Seed Oil, Ascophyllum Nodosum Extract, Glycyrrhiza Glabra Root Extract, Pancratium Maritimum Extract, Lactobacillus Ferment, Hydrolyzed Pea, Hydrolyzed Pea Protein, Bisabolol, Panthenol, Tocopherol, Arginine Lysine Polypeptide, Glucose, Pentapeptide-34 Trifluoroacetate, 2-Hexanediol, Caprylyl Glycol, C14-22 Alcohols, Xanthan Gum, Hydrogenated Hydrolysate Starch, C12-20 Alkyl Glucoside, Propanediol, Sorbitan Caprylate, Carbomer, Sodium Phytate, Sodium Succinate, Sodium Chloride, Sorbic Acid, Sodium Benzoate, Potassium Sorbate, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/dark-spots
- United Kingdom: https://lovi.care/skincare/uk/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/dark-spots
- Ireland: https://lovi.care/skincare/ie/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/dark-spots
- Germany: https://lovi.care/skincare/de/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/dark-spots
- France: https://lovi.care/skincare/fr/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/dark-spots
- Italy: https://lovi.care/skincare/it/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/dark-spots
- Netherlands: https://lovi.care/skincare/nl/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/dark-spots (this page)
- Spain: https://lovi.care/skincare/es/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/dark-spots
- Canada: https://lovi.care/skincare/ca/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/dark-spots
- Australia: https://lovi.care/skincare/au/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/dark-spots
- Singapore: https://lovi.care/skincare/sg/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/dark-spots
- Saudi Arabia: https://lovi.care/skincare/sa/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/dark-spots
- United Arab Emirates: https://lovi.care/skincare/ae/p/allies-of-skin/tranexamic-and-arbutin-advanced-brightening-serum/for/dark-spots