# Vitamin C and palmitoyl pentapeptide-4

Page: https://lovi.care/skincare/nl/ingredients/vitamin-c-and-palmitoyl-pentapeptide-4

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Depends on the strength

Use them at different times of day, with [vitamin C](https://lovi.care/skincare/nl/ingredients/vitamin-c) in the morning and the peptide in the evening, because they cancel each other out. Vitamin C brightens and protects the skin, while the peptide smooths fine lines and firms the skin. You can switch to using them on alternate days or wait ten minutes between steps if you want to use both.

[Microneedle-Mediated Delivery of Copper Peptide Through Skin](https://pubmed.ncbi.nlm.nih.gov/25690343/)

- [All about vitamin C](https://lovi.care/skincare/nl/ingredients/vitamin-c)
- [All about palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/palmitoyl-pentapeptide-4)

### [Vitamin C](https://lovi.care/skincare/nl/ingredients/vitamin-c) products

- [Olay Super Serum](https://lovi.care/skincare/nl/p/olay/super-serum/for/dry-skin) — High fit — [€192.17 at Amazon](https://www.amazon.nl/dp/B0HD7BBPY7?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Charlotte Tilbury Charlotte's Magic Cream](https://lovi.care/skincare/nl/p/charlotte-tilbury/charlotte-s-magic-cream/for/mature-skin) — Superior fit — [€94.90 at Notino](https://www.notino.nl/charlotte-tilbury/charlottes-magic-cream-verstevigende-hydraterende-creme-spf-15/p-16318756/)
- [RoC Retinol Correxion Deep Wrinkle Night Cream](https://lovi.care/skincare/nl/p/roc/retinol-correxion-deep-wrinkle-night-cream/for/dark-spots) — High fit — [€44.90 at Amazon](https://www.amazon.nl/dp/B0FMK54Q87?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Paula's Choice 1% Retinol Treatment](https://lovi.care/skincare/nl/p/paula-s-choice/1-retinol-treatment/for/dark-spots) — Superior fit — [€57.00 at Amazon](https://www.amazon.nl/dp/B07P6M914G?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Summer Fridays Jet Lag Mask](https://lovi.care/skincare/nl/p/summer-fridays/jet-lag-mask/for/dry-skin) — High fit
- [Mad Hippie Vitamin C Serum](https://lovi.care/skincare/nl/p/mad-hippie/vitamin-c-serum/for/dry-skin) — High fit — [€71.86 at Amazon](https://www.amazon.nl/dp/B00D8GKC2Y?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Eve Lom Renewal Treatment Oil](https://lovi.care/skincare/nl/p/eve-lom/renewal-treatment-oil/for/dry-sensitive-skin) — High fit
- [ZO Skin Health Exfoliating Polish](https://lovi.care/skincare/nl/p/zo-skin-health/exfoliating-polish/for/mature-skin) — High fit
- [CeraVe Skin Renewing Vitamin C Serum](https://lovi.care/skincare/nl/p/cerave/skin-renewing-vitamin-c-serum/for/acne-prone-skin) — High fit — [€29.75 at Amazon](https://www.amazon.nl/dp/B0FHPZ4KGH?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Eucerin Anti-Pigment Dual Serum](https://lovi.care/skincare/nl/p/eucerin/anti-pigment-dual-serum/for/oily-skin) — Average fit — [€44.14 at Amazon](https://www.amazon.nl/dp/B07Q8F9TZK?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [RoC Retinol Correxion Deep Wrinkle Serum](https://lovi.care/skincare/nl/p/roc/retinol-correxion-deep-wrinkle-serum/for/oily-skin) — Average fit — [€32.97 at Amazon](https://www.amazon.nl/dp/B0GQZ5J61H?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [iS Clinical Cleansing Complex](https://lovi.care/skincare/nl/p/is-clinical/cleansing-complex/for/oily-acne-prone-skin) — Superior fit — [€60.72 at Amazon](https://www.amazon.nl/dp/B000P6W6XI?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)

### [Palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/palmitoyl-pentapeptide-4) products

- [Olay Eye Lifting Serum](https://lovi.care/skincare/nl/p/olay/eye-lifting-serum/for/dry-skin) — High fit

## Questions and answers

### Can you use vitamin C and palmitoyl pentapeptide-4 together?

You should generally avoid using [vitamin C](https://lovi.care/skincare/nl/ingredients/vitamin-c) and [palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/palmitoyl-pentapeptide-4) together in the same routine, as they can reduce each other's effectiveness. Instead, use them in separate routines to help maintain their potency.

### Which goes first, vitamin C or palmitoyl pentapeptide-4?

You should use vitamin C and palmitoyl pentapeptide-4 in separate routines because combining [copper](https://lovi.care/skincare/nl/ingredients/copper) and peptides with vitamin C may reduce their effectiveness.

### Are vitamin C and palmitoyl pentapeptide-4 good for sensitive skin?

Yes, they can be good for sensitive skin depending on the strength and type used. Vitamin C and certain peptides may help improve photoaged skin.

[Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/) [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/)

## Research on vitamin C and palmitoyl pentapeptide-4

- [Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo](https://pubmed.ncbi.nlm.nih.gov/12823436/) Vitamin C · Experimental Dermatology, 2003
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Vitamin C · Journal of Cosmetic Dermatology, 2020
- [Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin](https://pubmed.ncbi.nlm.nih.gov/18492182/) Palmitoyl pentapeptide-4 · International Journal of Cosmetic Science, 2005
- [Stability, transdermal penetration, and cutaneous effects of ascorbic acid and its derivatives](https://pubmed.ncbi.nlm.nih.gov/23174055/) Vitamin C · Journal of Cosmetic Dermatology, 2012
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Vitamin C · Journal of Periodontology, 2009
- [Vitamin C mesotherapy versus topical application for gingival hyperpigmentation: a clinical and histopathological study](https://pubmed.ncbi.nlm.nih.gov/33966113/) Vitamin C · Clinical Oral Investigations, 2021
- [Skin moisturizing effect and skin penetration of ascorbyl palmitate entrapped in solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) incorporated into hydrogel](https://pubmed.ncbi.nlm.nih.gov/16259122/) Vitamin C · Die Pharmazie, 2005
- [Two superior antioxidants: Ferulic acid and ascorbic acid in reducing signs of photoaging-A split-face comparative study](https://pubmed.ncbi.nlm.nih.gov/34877760/) Vitamin C · Dermatologic Therapy, 2022
- [Ascorbic Acid Treatments as Effective and Safe Anti-Aging Therapies for Sensitive Skin](https://pubmed.ncbi.nlm.nih.gov/38397772/) Vitamin C · Antioxidants, 2024
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Vitamin C · Journal of Cosmetic Dermatology, 2019
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Vitamin C · International Journal of Cosmetic Science, 2009
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Vitamin C · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [Efficacy of cosmetic formulations containing dispersion of liposome with magnesium ascorbyl phosphate, alpha-lipoic acid and kinetin](https://pubmed.ncbi.nlm.nih.gov/22236139/) Vitamin C · Photochemistry and Photobiology, 2012
- [Derivatives of L-Ascorbic Acid in Emulgel: Development and Comprehensive Evaluation of the Topical Delivery System](https://pubmed.ncbi.nlm.nih.gov/36986679/) Vitamin C · Pharmaceutics, 2023
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Vitamin C · Drug Research, 2017
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) Vitamin C · Polymers, 2023
- [Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid](https://pubmed.ncbi.nlm.nih.gov/38794349/) Vitamin C · Pharmaceutics, 2024
- [Efficacy of ethyl ascorbyl ether-containing cosmetic cream on blue light-induced skin changes](https://pubmed.ncbi.nlm.nih.gov/34002928/) Vitamin C · Journal of Cosmetic Dermatology, 2022
- [Comparative physicochemical stability and clinical anti-wrinkle efficacy of transdermal emulgel preparations of 5% sodium ascorbyl phosphate and or ascorbic acid on human volunteers](https://pubmed.ncbi.nlm.nih.gov/32383548/) Vitamin C · Journal of Cosmetic Dermatology, 2021
- [Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials](https://pubmed.ncbi.nlm.nih.gov/41142247/) Vitamin C · Frontiers in Pharmacology, 2025
- [Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes](https://pubmed.ncbi.nlm.nih.gov/39778604/) Vitamin C · Free Radical Biology & Medicine, 2025
- [Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects](https://pubmed.ncbi.nlm.nih.gov/22142309/) Vitamin C · Experimental Dermatology, 2012
- [Moisturizing potentials of ascorbyl palmitate and calcium ascorbate in various topical formulations](https://pubmed.ncbi.nlm.nih.gov/18494922/) Vitamin C · International Journal of Cosmetic Science, 2004
- [Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients](https://pubmed.ncbi.nlm.nih.gov/41628877/) Vitamin C · International Journal of Biological Macromolecules, 2026
- [Liposomal formulation of a vitamin C derivative: a promising strategy to increase skin permeability](https://pubmed.ncbi.nlm.nih.gov/39985147/) Vitamin C · Journal of Liposome Research, 2025
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Vitamin C · International Journal of Molecular Sciences, 2024
- [Open-label topical application of tetrahexyldecyl ascorbate and acetyl zingerone containing serum improves the appearance of photoaging and uneven pigmentation](https://pubmed.ncbi.nlm.nih.gov/38634176/) Vitamin C · Journal of Cosmetic Dermatology, 2024
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Vitamin C · Cureus, 2026
- [Use of a Serum With the Infinite Glow® Device Improves Signs of Facial Aging: A Split-Face Case Report Using VISIA Analysis](https://pubmed.ncbi.nlm.nih.gov/42500768/) Palmitoyl pentapeptide-4 · Cureus, 2026

## Other combinations

- Keep them apart: [Vitamin C and salicylic acid](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-salicylic-acid)
- Keep them apart: [Vitamin C and retinol](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-retinol)
- Keep them apart: [Adapalene and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/adapalene-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Granactive retinoid and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/granactive-retinoid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Hydroxypinacolone retinoate and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/hydroxypinacolone-retinoate-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Pro-retinol and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/pro-retinol-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Retinal and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/retinal-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Retinoid blend and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/retinoid-blend-and-palmitoyl-pentapeptide-4)
- Depends on the strength: [Retinol and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/retinol-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Tretinoin and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/tretinoin-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Vitamin A and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/vitamin-a-and-palmitoyl-pentapeptide-4)
- Work well together: [Liposome and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/liposome-and-palmitoyl-pentapeptide-4)
- Work well together: [Microcapsule and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/microcapsule-and-palmitoyl-pentapeptide-4)
- Depends on the strength: [Vitamin C and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-acetyl-hexapeptide-3)
- Keep them apart: [Vitamin C and bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-bio-placenta-peptides)
- Keep them apart: [Vitamin C and collagen peptide](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-collagen-peptide)
- Keep them apart: [Vitamin C and copper](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-copper)
- Keep them apart: [Vitamin C and copper complex](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-copper-complex)
- Keep them apart: [Vitamin C and copper peptide](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-copper-peptide)
- Depends on the strength: [Vitamin C and hexapeptide](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-hexapeptide)
- Depends on the strength: [Vitamin C and hexapeptide-9](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-hexapeptide-9)
- Depends on the strength: [Vitamin C and palmitoyl tripeptide-1](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-palmitoyl-tripeptide-1)
- Keep them apart: [Vitamin C and peptide-rich plasma](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-peptide-rich-plasma)
- Keep them apart: [Vitamin C and triple peptide blend](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-triple-peptide-blend)
- Work well together: [Betaine and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/betaine-and-palmitoyl-pentapeptide-4)
- Work well together: [Glycerin and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/glycerin-and-palmitoyl-pentapeptide-4)
- Work well together: [Hyaluronic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/hyaluronic-acid-and-palmitoyl-pentapeptide-4)
- Depends on the strength: [Niacinamide and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/niacinamide-and-palmitoyl-pentapeptide-4)
- Work well together: [Panthenol and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/panthenol-and-palmitoyl-pentapeptide-4)
- Work well together: [Bakuchiol and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/bakuchiol-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Benzoyl peroxide and vitamin C](https://lovi.care/skincare/nl/ingredients/benzoyl-peroxide-and-vitamin-c)
- Work well together: [Arginine and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/arginine-and-palmitoyl-pentapeptide-4)
- Work well together: [GABA and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/gaba-and-palmitoyl-pentapeptide-4)
- Work well together: [Silk amino acids and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/silk-amino-acids-and-palmitoyl-pentapeptide-4)
- Work well together: [Taurine and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/taurine-and-palmitoyl-pentapeptide-4)
- Work well together: [Palmitoyl pentapeptide-4 and theanine](https://lovi.care/skincare/nl/ingredients/palmitoyl-pentapeptide-4-and-theanine)
- Keep them apart: [AHA blend glycolic and citric acids and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/aha-blend-glycolic-and-citric-acids-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Citric acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/citric-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Glycolic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/glycolic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Lactic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/lactic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Mandelic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/mandelic-acid-and-palmitoyl-pentapeptide-4)
- Work well together: [Coenzyme Q10 and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/coenzyme-q10-and-palmitoyl-pentapeptide-4)
- Work well together: [Green tea and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/green-tea-and-palmitoyl-pentapeptide-4)
- Work well together: [Vitamin E and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/vitamin-e-and-palmitoyl-pentapeptide-4)
- Work well together: [Beta-sitosterol and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/beta-sitosterol-and-palmitoyl-pentapeptide-4)
- Work well together: [Ceramide-building complex and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/ceramide-building-complex-and-palmitoyl-pentapeptide-4)
- Work well together: [Cholesterol and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/cholesterol-and-palmitoyl-pentapeptide-4)
- Work well together: [Phytosphingosine and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/phytosphingosine-and-palmitoyl-pentapeptide-4)
- Work well together: [Phytosterol and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/phytosterol-and-palmitoyl-pentapeptide-4)
- Work well together: [Squalene and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/squalene-and-palmitoyl-pentapeptide-4)
- Work well together: [Tri-ceramide complex and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/tri-ceramide-complex-and-palmitoyl-pentapeptide-4)
- Work well together: [Vitamin C and gluconolactone](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-gluconolactone)
- Work well together: [Vitamin C and lactobionic acid](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-lactobionic-acid)
- Keep them apart: [Salicylic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/salicylic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Adapalene and vitamin C](https://lovi.care/skincare/nl/ingredients/adapalene-and-vitamin-c)
- Keep them apart: [Vitamin C and granactive retinoid](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-granactive-retinoid)
- Keep them apart: [Vitamin C and hydroxypinacolone retinoate](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-hydroxypinacolone-retinoate)
- Keep them apart: [Vitamin C and pro-retinol](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-pro-retinol)
- Keep them apart: [Vitamin C and retinal](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-retinal)
- Keep them apart: [Vitamin C and retinoid blend](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-retinoid-blend)
- Keep them apart: [Vitamin C and tretinoin](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-tretinoin)
- Keep them apart: [Baking soda and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/baking-soda-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Bleach and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/bleach-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Potassium hydroxide and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/potassium-hydroxide-and-palmitoyl-pentapeptide-4)
- Work well together: [Vitamin C and baicalin](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-baicalin)
- Work well together: [Vitamin C and caffeic acid](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-caffeic-acid)
- Work well together: [Vitamin C and chrysin](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-chrysin)
- Work well together: [Vitamin C and ellagic acid](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-ellagic-acid)
- Work well together: [Vitamin C and ferulic acid](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-ferulic-acid)
- Work well together: [Vitamin C and hesperidin](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-hesperidin)
- Work well together: [Vitamin C and oxyresveratrol](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-oxyresveratrol)
- Work well together: [Vitamin C and phloretin](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-phloretin)
- Work well together: [Vitamin C and pterostilbene](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-pterostilbene)
- Work well together: [Vitamin C and resveratrol](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-resveratrol)
- Work well together: [Vitamin C and rutin](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-rutin)
- Work well together: [Vitamin C and silymarin](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-silymarin)
- Work well together: [Vitamin C and troxerutin](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-troxerutin)
- Keep them apart: [Behenyl alcohol and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/behenyl-alcohol-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Isopropyl alcohol and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/isopropyl-alcohol-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Polyvinyl alcohol and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/polyvinyl-alcohol-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Copper and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/copper-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Benzoyl peroxide and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/benzoyl-peroxide-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Vitamin C and behenyl alcohol](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-behenyl-alcohol)
- Keep them apart: [Vitamin C and isopropyl alcohol](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-isopropyl-alcohol)
- Keep them apart: [Vitamin C and polyvinyl alcohol](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-polyvinyl-alcohol)
- Keep them apart: [Magnesium and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/magnesium-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Zinc and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/zinc-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Zinc sulfate and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/zinc-sulfate-and-palmitoyl-pentapeptide-4)
- Work well together: [Vitamin C and hyaluronic acid](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-hyaluronic-acid)
- Keep them apart: [Vitamin C and baking soda](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-baking-soda)
- Keep them apart: [Vitamin C and bleach](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-bleach)
- Keep them apart: [Vitamin C and potassium hydroxide](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-potassium-hydroxide)
- Keep them apart: [Vitamin C and tromethamine](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-tromethamine)
- Work well together: [Vitamin C and vitamin E](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-vitamin-e)
- Keep them apart: [Azelaic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/azelaic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Protease and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/protease-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Superoxide dismutase and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/superoxide-dismutase-and-palmitoyl-pentapeptide-4)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/vitamin-c-and-palmitoyl-pentapeptide-4
- United Kingdom: https://lovi.care/skincare/uk/ingredients/vitamin-c-and-palmitoyl-pentapeptide-4
- Ireland: https://lovi.care/skincare/ie/ingredients/vitamin-c-and-palmitoyl-pentapeptide-4
- Germany: https://lovi.care/skincare/de/ingredients/vitamin-c-and-palmitoyl-pentapeptide-4
- France: https://lovi.care/skincare/fr/ingredients/vitamin-c-and-palmitoyl-pentapeptide-4
- Italy: https://lovi.care/skincare/it/ingredients/vitamin-c-and-palmitoyl-pentapeptide-4
- Netherlands: https://lovi.care/skincare/nl/ingredients/vitamin-c-and-palmitoyl-pentapeptide-4 (this page)
- Spain: https://lovi.care/skincare/es/ingredients/vitamin-c-and-palmitoyl-pentapeptide-4
- Canada: https://lovi.care/skincare/ca/ingredients/vitamin-c-and-palmitoyl-pentapeptide-4
- Australia: https://lovi.care/skincare/au/ingredients/vitamin-c-and-palmitoyl-pentapeptide-4
- Singapore: https://lovi.care/skincare/sg/ingredients/vitamin-c-and-palmitoyl-pentapeptide-4
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/vitamin-c-and-palmitoyl-pentapeptide-4
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/vitamin-c-and-palmitoyl-pentapeptide-4