# Tretinoin and bio-placenta peptides

Page: https://lovi.care/skincare/nl/ingredients/tretinoin-and-bio-placenta-peptides

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Keep them apart

Use them at different times of day, applying your peptides in the morning and [tretinoin](https://lovi.care/skincare/nl/ingredients/tretinoin) at night to prevent irritation. Using both strong ingredients at the same time can make skin overly sensitive and red. You can alternate their use or switch to a gentler peptide formula if irritation happens.

- [All about tretinoin](https://lovi.care/skincare/nl/ingredients/tretinoin)
- [All about bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides)

### [Tretinoin](https://lovi.care/skincare/nl/ingredients/tretinoin) products

- [Retin-A Cream](https://lovi.care/skincare/nl/p/retin-a/cream/for/oily-skin) — High fit
- [Tri-Luma Cream](https://lovi.care/skincare/nl/p/tri-luma/cream/for/dark-spots) — Average fit
- [Musely The Spot Cream](https://lovi.care/skincare/nl/p/musely/the-spot-cream/for/mature-skin) — High fit
- [Obagi Tretinoin Cream 0.05%](https://lovi.care/skincare/nl/p/obagi/tretinoin-cream-0-05/for/oily-skin) — High fit
- [Taro Tretinoin Cream](https://lovi.care/skincare/nl/p/taro/tretinoin-cream/for/combination-skin) — High fit
- [Mylan Tretinoin](https://lovi.care/skincare/nl/p/mylan/tretinoin/for/acne-prone-skin) — Average fit
- [Curology Formula](https://lovi.care/skincare/nl/p/curology/formula/for/oily-skin) — High fit
- [Menarini A-Ret Gel](https://lovi.care/skincare/nl/p/menarini/a-ret-gel/for/oily-skin) — High fit

### [Bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides) products

- [LION POSE PEP TALK](https://lovi.care/skincare/nl/p/lion-pose/pep-talk/for/dry-skin) — Average fit

## Questions and answers

### Can you use tretinoin and bio-placenta peptides together?

No, you should keep [tretinoin](https://lovi.care/skincare/nl/ingredients/tretinoin) and [bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides) apart in your routine because combining them may increase skin irritation. Instead, alternate their usage by applying your retinoid in the evening and peptides in the morning.

### Which goes first, tretinoin or bio-placenta peptides?

Keep tretinoin and bio-placenta peptides apart by using them at different times, such as applying your retinoid in the evening and peptides in the morning.

### Are tretinoin and bio-placenta peptides good for sensitive skin?

Keep tretinoin and bio-placenta peptides apart in your routine because combining them may increase irritation. Alternate their usage by applying your retinoid at night and peptides in the morning.

## Research on tretinoin and bio-placenta peptides

- [Restoration of collagen formation in photodamaged human skin by tretinoin (retinoic acid)](https://pubmed.ncbi.nlm.nih.gov/8336752/) Tretinoin · The New England Journal of Medicine, 1993
- [Clinical Assessment of New Topical Cream Containing Two Essential Oils Combined with Tretinoin in the Treatment of Acne](https://pubmed.ncbi.nlm.nih.gov/32210603/) Tretinoin · Clinical, Cosmetic and Investigational Dermatology, 2020
- [Efficacy assessments of tretinoin-loaded nano lipid carriers in acne vulgaris: a double blind, split-face randomized clinical study](https://pubmed.ncbi.nlm.nih.gov/34146120/) Tretinoin · Archives of Dermatological Research, 2022
- [Topical tretinoin for treating photoaging: A systematic review of randomized controlled trials](https://pubmed.ncbi.nlm.nih.gov/35620028/) Tretinoin · International Journal of Women's Dermatology, 2022

## Other combinations

- Keep them apart: [Tretinoin and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/tretinoin-and-acetyl-hexapeptide-3)
- Keep them apart: [Adapalene and bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/adapalene-and-bio-placenta-peptides)
- Keep them apart: [Bio-placenta peptides and granactive retinoid](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-granactive-retinoid)
- Keep them apart: [Bio-placenta peptides and hydroxypinacolone retinoate](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-hydroxypinacolone-retinoate)
- Keep them apart: [Bio-placenta peptides and pro-retinol](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-pro-retinol)
- Keep them apart: [Bio-placenta peptides and retinal](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-retinal)
- Keep them apart: [Bio-placenta peptides and retinoid blend](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-retinoid-blend)
- Depends on the strength: [Retinol and bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/retinol-and-bio-placenta-peptides)
- Keep them apart: [Bio-placenta peptides and vitamin A](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-vitamin-a)
- Keep them apart: [Tretinoin and collagen peptide](https://lovi.care/skincare/nl/ingredients/tretinoin-and-collagen-peptide)
- Keep them apart: [Tretinoin and copper peptide](https://lovi.care/skincare/nl/ingredients/tretinoin-and-copper-peptide)
- Keep them apart: [Tretinoin and hexapeptide](https://lovi.care/skincare/nl/ingredients/tretinoin-and-hexapeptide)
- Keep them apart: [Tretinoin and hexapeptide-9](https://lovi.care/skincare/nl/ingredients/tretinoin-and-hexapeptide-9)
- Keep them apart: [Tretinoin and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/tretinoin-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Tretinoin and palmitoyl tripeptide-1](https://lovi.care/skincare/nl/ingredients/tretinoin-and-palmitoyl-tripeptide-1)
- Keep them apart: [Tretinoin and peptide-rich plasma](https://lovi.care/skincare/nl/ingredients/tretinoin-and-peptide-rich-plasma)
- Keep them apart: [Tretinoin and triple peptide blend](https://lovi.care/skincare/nl/ingredients/tretinoin-and-triple-peptide-blend)
- Work well together: [Bio-placenta peptides and liposome](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-liposome)
- Work well together: [Bio-placenta peptides and microcapsule](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-microcapsule)
- Keep them apart: [Vitamin C and bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-bio-placenta-peptides)
- Depends on the strength: [Niacinamide and tretinoin](https://lovi.care/skincare/nl/ingredients/niacinamide-and-tretinoin)
- Work well together: [Bio-placenta peptides and betaine](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-betaine)
- Work well together: [Glycerin and bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/glycerin-and-bio-placenta-peptides)
- Work well together: [Bio-placenta peptides and hyaluronic acid](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-hyaluronic-acid)
- Depends on the strength: [Niacinamide and bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/niacinamide-and-bio-placenta-peptides)
- Work well together: [Panthenol and bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/panthenol-and-bio-placenta-peptides)
- Work well together: [Bio-placenta peptides and bakuchiol](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-bakuchiol)
- Work well together: [Bio-placenta peptides and arginine](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-arginine)
- Work well together: [Bio-placenta peptides and GABA](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-gaba)
- Work well together: [Bio-placenta peptides and silk amino acids](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-silk-amino-acids)
- Work well together: [Bio-placenta peptides and taurine](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-taurine)
- Work well together: [Bio-placenta peptides and theanine](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-theanine)
- Keep them apart: [AHA blend glycolic and citric acids and bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/aha-blend-glycolic-and-citric-acids-and-bio-placenta-peptides)
- Keep them apart: [Bio-placenta peptides and citric acid](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-citric-acid)
- Keep them apart: [Glycolic acid and bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/glycolic-acid-and-bio-placenta-peptides)
- Keep them apart: [Bio-placenta peptides and lactic acid](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-lactic-acid)
- Keep them apart: [Bio-placenta peptides and mandelic acid](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-mandelic-acid)
- Work well together: [Bio-placenta peptides and coenzyme q10](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-coenzyme-q10)
- Work well together: [Green tea and bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/green-tea-and-bio-placenta-peptides)
- Work well together: [Bio-placenta peptides and vitamin E](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-vitamin-e)
- Keep them apart: [AHA blend glycolic and citric acids and tretinoin](https://lovi.care/skincare/nl/ingredients/aha-blend-glycolic-and-citric-acids-and-tretinoin)
- Keep them apart: [Tretinoin and citric acid](https://lovi.care/skincare/nl/ingredients/tretinoin-and-citric-acid)
- Keep them apart: [Glycolic acid and tretinoin](https://lovi.care/skincare/nl/ingredients/glycolic-acid-and-tretinoin)
- Keep them apart: [Tretinoin and lactic acid](https://lovi.care/skincare/nl/ingredients/tretinoin-and-lactic-acid)
- Keep them apart: [Tretinoin and mandelic acid](https://lovi.care/skincare/nl/ingredients/tretinoin-and-mandelic-acid)
- Work well together: [Bio-placenta peptides and beta-sitosterol](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-beta-sitosterol)
- Work well together: [Ceramide-building complex and bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/ceramide-building-complex-and-bio-placenta-peptides)
- Work well together: [Bio-placenta peptides and cholesterol](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-cholesterol)
- Work well together: [Bio-placenta peptides and phytosphingosine](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-phytosphingosine)
- Work well together: [Bio-placenta peptides and phytosterol](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-phytosterol)
- Work well together: [Bio-placenta peptides and squalene](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-squalene)
- Work well together: [Bio-placenta peptides and tri-ceramide complex](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-tri-ceramide-complex)
- Keep them apart: [Salicylic acid and bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/salicylic-acid-and-bio-placenta-peptides)
- Keep them apart: [Salicylic acid and tretinoin](https://lovi.care/skincare/nl/ingredients/salicylic-acid-and-tretinoin)
- Keep them apart: [Vitamin C and tretinoin](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-tretinoin)
- Keep them apart: [Bio-placenta peptides and baking soda](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-baking-soda)
- Keep them apart: [Bio-placenta peptides and bleach](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-bleach)
- Keep them apart: [Bio-placenta peptides and potassium hydroxide](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-potassium-hydroxide)
- Keep them apart: [Bio-placenta peptides and behenyl alcohol](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-behenyl-alcohol)
- Keep them apart: [Bio-placenta peptides and isopropyl alcohol](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-isopropyl-alcohol)
- Keep them apart: [Bio-placenta peptides and polyvinyl alcohol](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-polyvinyl-alcohol)
- Keep them apart: [Bio-placenta peptides and copper](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-copper)
- Keep them apart: [Benzoyl peroxide and tretinoin](https://lovi.care/skincare/nl/ingredients/benzoyl-peroxide-and-tretinoin)
- Keep them apart: [Bio-placenta peptides and magnesium](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-magnesium)
- Keep them apart: [Bio-placenta peptides and zinc](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-zinc)
- Keep them apart: [Bio-placenta peptides and zinc sulfate](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-zinc-sulfate)
- Keep them apart: [Benzoyl peroxide and bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/benzoyl-peroxide-and-bio-placenta-peptides)
- Keep them apart: [Azelaic acid and bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/azelaic-acid-and-bio-placenta-peptides)
- Keep them apart: [Bio-placenta peptides and protease](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-protease)
- Keep them apart: [Bio-placenta peptides and superoxide dismutase](https://lovi.care/skincare/nl/ingredients/bio-placenta-peptides-and-superoxide-dismutase)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/tretinoin-and-bio-placenta-peptides
- United Kingdom: https://lovi.care/skincare/uk/ingredients/tretinoin-and-bio-placenta-peptides
- Ireland: https://lovi.care/skincare/ie/ingredients/tretinoin-and-bio-placenta-peptides
- Germany: https://lovi.care/skincare/de/ingredients/tretinoin-and-bio-placenta-peptides
- France: https://lovi.care/skincare/fr/ingredients/tretinoin-and-bio-placenta-peptides
- Italy: https://lovi.care/skincare/it/ingredients/tretinoin-and-bio-placenta-peptides
- Netherlands: https://lovi.care/skincare/nl/ingredients/tretinoin-and-bio-placenta-peptides (this page)
- Spain: https://lovi.care/skincare/es/ingredients/tretinoin-and-bio-placenta-peptides
- Canada: https://lovi.care/skincare/ca/ingredients/tretinoin-and-bio-placenta-peptides
- Australia: https://lovi.care/skincare/au/ingredients/tretinoin-and-bio-placenta-peptides
- Singapore: https://lovi.care/skincare/sg/ingredients/tretinoin-and-bio-placenta-peptides
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/tretinoin-and-bio-placenta-peptides
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/tretinoin-and-bio-placenta-peptides