# Niacinamide and acetyl hexapeptide-3 Page: https://lovi.care/skincare/nl/ingredients/niacinamide-and-acetyl-hexapeptide-3 The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands. Depends on the strength Use them together in the same routine, because [niacinamide](https://lovi.care/skincare/nl/ingredients/niacinamide) helps strengthen your skin while peptides work on firmness. Niacinamide boosts your skin barrier and pairs wonderfully with peptides to improve overall anti-aging results. You can keep using them both together without making any changes. - [All about niacinamide](https://lovi.care/skincare/nl/ingredients/niacinamide) - [All about acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3) ### [Niacinamide](https://lovi.care/skincare/nl/ingredients/niacinamide) products - [La Roche-Posay Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/oily-acne-prone-skin) — High fit — [€72.93 at Amazon](https://www.amazon.nl/dp/B01N9SPQHQ?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/nl/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [€21.00 at Amazon](https://www.amazon.nl/dp/B01N1LL62W?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [Cetaphil Gentle Skin Cleanser](https://lovi.care/skincare/nl/p/cetaphil/gentle-skin-cleanser/for/dry-skin) — Superior fit — [€13.45 at Amazon](https://www.amazon.nl/dp/B0CDXXGBK4?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [€21.95 at Amazon](https://www.amazon.nl/dp/B01N7T7JKJ?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [Dr. Althea 345 Relief Cream](https://lovi.care/skincare/nl/p/dr-althea/345-relief-cream/for/acne-prone-skin) — Superior fit — [€61.59 at Amazon](https://www.amazon.nl/dp/B0FMDRCHXV?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [Biodance Bio-Collagen Real Deep Mask](https://lovi.care/skincare/nl/p/biodance/bio-collagen-real-deep-mask/for/mature-skin) — Superior fit — [€4.70 at Amazon](https://www.amazon.nl/dp/B0D8B9MKMV?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [Olay Regenerist Micro-Sculpting Cream](https://lovi.care/skincare/nl/p/olay/regenerist-micro-sculpting-cream/for/mature-skin) — Superior fit — [€54.97 at Amazon](https://www.amazon.nl/dp/B00AZHHMLS?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [CeraVe Resurfacing Retinol Serum](https://lovi.care/skincare/nl/p/cerave/resurfacing-retinol-serum/for/dark-spots) — High fit — [€22.50 at Notino](https://www.notino.nl/cerave/blemish-control-active-serum-met-ratinol/p-16142856/) - [CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/nl/p/cerave/pm-facial-moisturizing-lotion/for/acne-prone-skin) — Superior fit — [€38.53 at Lookfantastic](https://www.lookfantastic.nl/p/cerave-evening-moisturising-routine-for-dry-skin-face-and-body-moisturiser-with-hyaluronic-acid/15370764/) - [Medicube PDRN Pink Peptide Serum](https://lovi.care/skincare/nl/p/medicube/pdrn-pink-peptide-serum/for/mature-skin) — High fit — [€18.80 at Amazon](https://www.amazon.nl/dp/B0DCJ7952P?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [CeraVe Renewing SA Cleanser](https://lovi.care/skincare/nl/p/cerave/renewing-sa-cleanser/for/oily-acne-prone-skin) — High fit — [€18.92 at Amazon](https://www.amazon.nl/dp/B09MMJS8ZM?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [Medicube Collagen Jelly Cream](https://lovi.care/skincare/nl/p/medicube/collagen-jelly-cream/for/mature-skin) — Superior fit — [€19.21 at Amazon](https://www.amazon.nl/dp/B0CM2PPNMW?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) ### [Acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3) products - [The Ordinary Multi-Peptide + Copper Peptides 1% Serum](https://lovi.care/skincare/nl/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/mature-skin) — High fit — [€34.95 at Amazon](https://www.amazon.nl/dp/B0C9DXGXZ3?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [The Ordinary Multi-Peptide + HA Serum](https://lovi.care/skincare/nl/p/the-ordinary/multi-peptide-ha-serum/for/dry-skin) — Superior fit — [€18.29 at Amazon](https://www.amazon.nl/dp/B0BLHW7JZM?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [Medik8 Liquid Peptides](https://lovi.care/skincare/nl/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [€98.05 at Amazon](https://www.amazon.nl/dp/B0DSJNWVV6?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [La Mer The Treatment Lotion](https://lovi.care/skincare/nl/p/la-mer/the-treatment-lotion/for/mature-skin) — Superior fit — [€143.70 at Amazon](https://www.amazon.nl/dp/B0B61KKT4K?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [The Ordinary Argireline Solution 10%](https://lovi.care/skincare/nl/p/the-ordinary/argireline-solution-10/for/mature-skin) — Average fit — [€10.58 at Amazon](https://www.amazon.nl/dp/B072JH13CD?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [Good Molecules Super Peptide Serum](https://lovi.care/skincare/nl/p/good-molecules/super-peptide-serum/for/mature-skin) — High fit — [€23.92 at Amazon](https://www.amazon.nl/dp/B091MTKS35?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [Clinique Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/nl/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/mature-skin) — Average fit — [€93.33 at Amazon](https://www.amazon.nl/dp/B0CY5JHJ9C?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [La Mer The Renewal Oil](https://lovi.care/skincare/nl/p/la-mer/the-renewal-oil/for/mature-skin) — High fit — [€201.44 at Amazon](https://www.amazon.nl/dp/B0163GAMI4?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [Estée Lauder Micro Essence Treatment Lotion](https://lovi.care/skincare/nl/p/estee-lauder/micro-essence-treatment-lotion/for/oily-acne-prone-skin) — Superior fit — [€85.99 at Amazon](https://www.amazon.nl/dp/B09Y3DG7WT?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [The INKEY List Collagen Peptide Serum](https://lovi.care/skincare/nl/p/the-inkey-list/collagen-peptide-serum/for/dry-sensitive-skin) — High fit - [La Mer The Eye Concentrate](https://lovi.care/skincare/nl/p/la-mer/the-eye-concentrate/for/mature-skin) — High fit — [€189.00 at Amazon](https://www.amazon.nl/dp/B085614WX5?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [NATURIUM Multi-Peptide Advanced Serum](https://lovi.care/skincare/nl/p/naturium/multi-peptide-advanced-serum/for/mature-skin) — High fit ## Questions and answers ### Can you use niacinamide and acetyl hexapeptide-3 together? Yes, you can use [niacinamide](https://lovi.care/skincare/nl/ingredients/niacinamide) and [acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3) together depending on the strength, and they are found together in products like Rhode Peptide Glazing Fluid and La Mer The Regenerating [Serum](https://lovi.care/skincare/nl/ingredients/serum). This combination helps strengthen the skin barrier and complement peptide regeneration. Clinical trials show that using these ingredients together helps reduce the progression of skin aging. [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/) [American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/) ### Which goes first, niacinamide or acetyl hexapeptide-3? Whether niacinamide or acetyl hexapeptide-3 goes first depends on the product strength you are using. You can find both ingredients together in finished products like Rhode Peptide Glazing Fluid and Heimish Marine Care Eye Cream. ### Are niacinamide and acetyl hexapeptide-3 good for sensitive skin? Niacinamide and acetyl hexapeptide-3 depend on the product strength for sensitive skin, and they are ideal together in anti-aging and barrier repair products to strengthen the skin barrier. Products like Heimish Marine Care Eye Cream and Rhode Peptide Glazing Fluid contain both ingredients. ## Research on niacinamide and acetyl hexapeptide-3 - [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002 - [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021 - [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021 - [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-3 · American Journal of Clinical Dermatology, 2013 - [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024 - [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-3 · Annals of Dermatology, 2019 - [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-3 · Journal of Cosmetic Dermatology, 2017 - [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-3 · Journal of Cosmetic and Laser Therapy, 2013 ## Other combinations - Depends on the strength: [Retinol and niacinamide](https://lovi.care/skincare/nl/ingredients/retinol-and-niacinamide) - Depends on the strength: [AHA blend glycolic and citric acids and niacinamide](https://lovi.care/skincare/nl/ingredients/aha-blend-glycolic-and-citric-acids-and-niacinamide) - Depends on the strength: [Niacinamide and citric acid](https://lovi.care/skincare/nl/ingredients/niacinamide-and-citric-acid) - Depends on the strength: [Glycolic acid and niacinamide](https://lovi.care/skincare/nl/ingredients/glycolic-acid-and-niacinamide) - Depends on the strength: [Niacinamide and lactic acid](https://lovi.care/skincare/nl/ingredients/niacinamide-and-lactic-acid) - Depends on the strength: [Niacinamide and mandelic acid](https://lovi.care/skincare/nl/ingredients/niacinamide-and-mandelic-acid) - Depends on the strength: [Niacinamide and salicylic acid](https://lovi.care/skincare/nl/ingredients/niacinamide-and-salicylic-acid) - Keep them apart: [Adapalene and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/adapalene-and-acetyl-hexapeptide-3) - Keep them apart: [Acetyl hexapeptide-3 and granactive retinoid](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-granactive-retinoid) - Keep them apart: [Acetyl hexapeptide-3 and hydroxypinacolone retinoate](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-hydroxypinacolone-retinoate) - Keep them apart: [Pro-retinol and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/pro-retinol-and-acetyl-hexapeptide-3) - Keep them apart: [Retinal and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/retinal-and-acetyl-hexapeptide-3) - Keep them apart: [Acetyl hexapeptide-3 and retinoid blend](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-retinoid-blend) - Depends on the strength: [Retinol and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/retinol-and-acetyl-hexapeptide-3) - Keep them apart: [Tretinoin and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/tretinoin-and-acetyl-hexapeptide-3) - Keep them apart: [Vitamin A and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/vitamin-a-and-acetyl-hexapeptide-3) - Work well together: [Liposome and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/liposome-and-acetyl-hexapeptide-3) - Work well together: [Acetyl hexapeptide-3 and microcapsule](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-microcapsule) - Depends on the strength: [Vitamin C and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/vitamin-c-and-acetyl-hexapeptide-3) - Depends on the strength: [Niacinamide and gluconolactone](https://lovi.care/skincare/nl/ingredients/niacinamide-and-gluconolactone) - Depends on the strength: [Niacinamide and lactobionic acid](https://lovi.care/skincare/nl/ingredients/niacinamide-and-lactobionic-acid) - Work well together: [Niacinamide and cholesterol](https://lovi.care/skincare/nl/ingredients/niacinamide-and-cholesterol) - Work well together: [Niacinamide and lauric acid](https://lovi.care/skincare/nl/ingredients/niacinamide-and-lauric-acid) - Work well together: [Niacinamide and linoleic acid](https://lovi.care/skincare/nl/ingredients/niacinamide-and-linoleic-acid) - Work well together: [Niacinamide and tri-ceramide complex](https://lovi.care/skincare/nl/ingredients/niacinamide-and-tri-ceramide-complex) - Depends on the strength: [Adapalene and niacinamide](https://lovi.care/skincare/nl/ingredients/adapalene-and-niacinamide) - Depends on the strength: [Niacinamide and granactive retinoid](https://lovi.care/skincare/nl/ingredients/niacinamide-and-granactive-retinoid) - Depends on the strength: [Niacinamide and hydroxypinacolone retinoate](https://lovi.care/skincare/nl/ingredients/niacinamide-and-hydroxypinacolone-retinoate) - Depends on the strength: [Niacinamide and pro-retinol](https://lovi.care/skincare/nl/ingredients/niacinamide-and-pro-retinol) - Depends on the strength: [Niacinamide and retinal](https://lovi.care/skincare/nl/ingredients/niacinamide-and-retinal) - Depends on the strength: [Niacinamide and retinoid blend](https://lovi.care/skincare/nl/ingredients/niacinamide-and-retinoid-blend) - Depends on the strength: [Niacinamide and tretinoin](https://lovi.care/skincare/nl/ingredients/niacinamide-and-tretinoin) - Depends on the strength: [Niacinamide and vitamin A](https://lovi.care/skincare/nl/ingredients/niacinamide-and-vitamin-a) - Work well together: [Acetyl hexapeptide-3 and betaine](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-betaine) - Work well together: [Glycerin and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/glycerin-and-acetyl-hexapeptide-3) - Work well together: [Acetyl hexapeptide-3 and hyaluronic acid](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid) - Work well together: [Panthenol and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/panthenol-and-acetyl-hexapeptide-3) - Depends on the strength: [Niacinamide and bio-placenta peptides](https://lovi.care/skincare/nl/ingredients/niacinamide-and-bio-placenta-peptides) - Depends on the strength: [Niacinamide and collagen peptide](https://lovi.care/skincare/nl/ingredients/niacinamide-and-collagen-peptide) - Depends on the strength: [Niacinamide and copper peptide](https://lovi.care/skincare/nl/ingredients/niacinamide-and-copper-peptide) - Depends on the strength: [Niacinamide and hexapeptide](https://lovi.care/skincare/nl/ingredients/niacinamide-and-hexapeptide) - Depends on the strength: [Niacinamide and hexapeptide-9](https://lovi.care/skincare/nl/ingredients/niacinamide-and-hexapeptide-9) - Depends on the strength: [Niacinamide and palmitoyl pentapeptide-4](https://lovi.care/skincare/nl/ingredients/niacinamide-and-palmitoyl-pentapeptide-4) - Depends on the strength: [Niacinamide and palmitoyl tripeptide-1](https://lovi.care/skincare/nl/ingredients/niacinamide-and-palmitoyl-tripeptide-1) - Depends on the strength: [Niacinamide and peptide-rich plasma](https://lovi.care/skincare/nl/ingredients/niacinamide-and-peptide-rich-plasma) - Depends on the strength: [Niacinamide and triple peptide blend](https://lovi.care/skincare/nl/ingredients/niacinamide-and-triple-peptide-blend) - Work well together: [Bakuchiol and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/bakuchiol-and-acetyl-hexapeptide-3) - Work well together: [Arginine and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/arginine-and-acetyl-hexapeptide-3) - Work well together: [Acetyl hexapeptide-3 and GABA](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-gaba) - Work well together: [Silk amino acids and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/silk-amino-acids-and-acetyl-hexapeptide-3) - Work well together: [Taurine and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/taurine-and-acetyl-hexapeptide-3) - Work well together: [Acetyl hexapeptide-3 and theanine](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-theanine) - Work well together: [Niacinamide and hyaluronic acid](https://lovi.care/skincare/nl/ingredients/niacinamide-and-hyaluronic-acid) - Keep them apart: [AHA blend glycolic and citric acids and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/aha-blend-glycolic-and-citric-acids-and-acetyl-hexapeptide-3) - Keep them apart: [Acetyl hexapeptide-3 and citric acid](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-citric-acid) - Keep them apart: [Glycolic acid and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/glycolic-acid-and-acetyl-hexapeptide-3) - Keep them apart: [Lactic acid and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/lactic-acid-and-acetyl-hexapeptide-3) - Keep them apart: [Acetyl hexapeptide-3 and mandelic acid](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-mandelic-acid) - Work well together: [Coenzyme Q10 and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3) - Work well together: [Green tea and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/green-tea-and-acetyl-hexapeptide-3) - Work well together: [Vitamin E and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/vitamin-e-and-acetyl-hexapeptide-3) - Work well together: [Acetyl hexapeptide-3 and beta-sitosterol](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-beta-sitosterol) - Work well together: [Ceramide-building complex and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/ceramide-building-complex-and-acetyl-hexapeptide-3) - Work well together: [Acetyl hexapeptide-3 and cholesterol](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-cholesterol) - Work well together: [Acetyl hexapeptide-3 and phytosphingosine](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-phytosphingosine) - Work well together: [Acetyl hexapeptide-3 and phytosterol](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-phytosterol) - Work well together: [Acetyl hexapeptide-3 and squalene](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-squalene) - Work well together: [Acetyl hexapeptide-3 and tri-ceramide complex](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-tri-ceramide-complex) - Work well together: [Niacinamide and bakuchiol](https://lovi.care/skincare/nl/ingredients/niacinamide-and-bakuchiol) - Keep them apart: [Salicylic acid and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/salicylic-acid-and-acetyl-hexapeptide-3) - Keep them apart: [Acetyl hexapeptide-3 and baking soda](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-baking-soda) - Keep them apart: [Acetyl hexapeptide-3 and bleach](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-bleach) - Keep them apart: [Acetyl hexapeptide-3 and potassium hydroxide](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-potassium-hydroxide) - Keep them apart: [Acetyl hexapeptide-3 and behenyl alcohol](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-behenyl-alcohol) - Keep them apart: [Acetyl hexapeptide-3 and isopropyl alcohol](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-isopropyl-alcohol) - Keep them apart: [Acetyl hexapeptide-3 and polyvinyl alcohol](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-polyvinyl-alcohol) - Work well together: [Niacinamide and zinc](https://lovi.care/skincare/nl/ingredients/niacinamide-and-zinc) - Work well together: [Niacinamide and zinc gluconate](https://lovi.care/skincare/nl/ingredients/niacinamide-and-zinc-gluconate) - Work well together: [Niacinamide and zinc oxide](https://lovi.care/skincare/nl/ingredients/niacinamide-and-zinc-oxide) - Work well together: [Niacinamide and zinc sulfate](https://lovi.care/skincare/nl/ingredients/niacinamide-and-zinc-sulfate) - Work well together: [Benzoyl peroxide and niacinamide](https://lovi.care/skincare/nl/ingredients/benzoyl-peroxide-and-niacinamide) - Keep them apart: [Niacinamide and lipohydroxy acid](https://lovi.care/skincare/nl/ingredients/niacinamide-and-lipohydroxy-acid) - Keep them apart: [Copper and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/copper-and-acetyl-hexapeptide-3) - Work well together: [Ferulic acid and niacinamide](https://lovi.care/skincare/nl/ingredients/ferulic-acid-and-niacinamide) - Work well together: [Green tea and niacinamide](https://lovi.care/skincare/nl/ingredients/green-tea-and-niacinamide) - Work well together: [Niacinamide and vitamin E](https://lovi.care/skincare/nl/ingredients/niacinamide-and-vitamin-e) - Keep them apart: [Niacinamide and isopropyl alcohol](https://lovi.care/skincare/nl/ingredients/niacinamide-and-isopropyl-alcohol) - Keep them apart: [Magnesium and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/magnesium-and-acetyl-hexapeptide-3) - Keep them apart: [Acetyl hexapeptide-3 and zinc](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-zinc) - Keep them apart: [Acetyl hexapeptide-3 and zinc sulfate](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-zinc-sulfate) - Keep them apart: [Benzoyl peroxide and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/benzoyl-peroxide-and-acetyl-hexapeptide-3) - Work well together: [Niacinamide and ascorbyl glucoside](https://lovi.care/skincare/nl/ingredients/niacinamide-and-ascorbyl-glucoside) - Keep them apart: [Azelaic acid and acetyl hexapeptide-3](https://lovi.care/skincare/nl/ingredients/azelaic-acid-and-acetyl-hexapeptide-3) - Keep them apart: [Acetyl hexapeptide-3 and protease](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-protease) - Keep them apart: [Acetyl hexapeptide-3 and superoxide dismutase](https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-superoxide-dismutase) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/ingredients/niacinamide-and-acetyl-hexapeptide-3 - United Kingdom: https://lovi.care/skincare/uk/ingredients/niacinamide-and-acetyl-hexapeptide-3 - Ireland: https://lovi.care/skincare/ie/ingredients/niacinamide-and-acetyl-hexapeptide-3 - Germany: https://lovi.care/skincare/de/ingredients/niacinamide-and-acetyl-hexapeptide-3 - France: https://lovi.care/skincare/fr/ingredients/niacinamide-and-acetyl-hexapeptide-3 - Italy: https://lovi.care/skincare/it/ingredients/niacinamide-and-acetyl-hexapeptide-3 - Netherlands: https://lovi.care/skincare/nl/ingredients/niacinamide-and-acetyl-hexapeptide-3 (this page) - Spain: https://lovi.care/skincare/es/ingredients/niacinamide-and-acetyl-hexapeptide-3 - Canada: https://lovi.care/skincare/ca/ingredients/niacinamide-and-acetyl-hexapeptide-3 - Australia: https://lovi.care/skincare/au/ingredients/niacinamide-and-acetyl-hexapeptide-3 - Singapore: https://lovi.care/skincare/sg/ingredients/niacinamide-and-acetyl-hexapeptide-3 - Saudi Arabia: https://lovi.care/skincare/sa/ingredients/niacinamide-and-acetyl-hexapeptide-3 - United Arab Emirates: https://lovi.care/skincare/ae/ingredients/niacinamide-and-acetyl-hexapeptide-3