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Citric acid and peptide-rich plasma

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes · How the Fit score works

Citric acid and peptide-rich plasma: keep them apart

Keep them apart

Apply the peptide serum in the morning and the citric acid at night to prevent the acid from breaking down the peptides. Citric acid makes the skin too acidic, which ruins the firming power of peptides and makes them useless. You can use both if you space them out by several hours or switch to gentler products.

Citric acid products

Peptide-rich plasma products

Questions and answers

Can you use citric acid and peptide-rich plasma together?

No, you should keep citric acid and peptide-rich plasma apart because the low pH of the acid destabilizes the peptides and reduces their activity. Use them in separate steps or routines, such as applying one in the morning and the other at night.

Which goes first, citric acid or peptide-rich plasma?

Keep citric acid and peptide-rich plasma apart by using them in separate steps or routines, such as morning and evening separation. The acidic environment of citric acid may destabilize peptide bonds and reduce their bioactivity if combined.

Are citric acid and peptide-rich plasma good for sensitive skin?

Citric acid and peptide-rich plasma are best kept apart in your routine, especially for sensitive skin, because the low pH of the acid may destabilize the peptide bonds and reduce their effectiveness. Use them in separate steps or routines instead.

Research on citric acid and peptide-rich plasma

Behind this pairing advice

Lovi checks every pairing with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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