# Weleda vs Sesderma

Page: https://lovi.care/skincare/nl/compare/weleda-vs-sesderma

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Weleda and Sesderma are distinguished skincare brands rooted in botanical and scientific traditions, respectively. The Swiss brand, founded in 1921, is widely loved for its rich moisturizers and meticulously crafted formulas that suit sensitive skin best, offering targeted relief for acne-prone skin with the Skin Food Light and addressing dark spots with the Skin Food. Meanwhile, the Spanish brand, founded in 1989, is beloved for its advanced [serums](https://lovi.care/skincare/nl/ingredients/serum) and meticulously engineered formulas, suiting sensitive, hyperpigmented, and aging skin types best with standout solutions like the Azelac RU Serum for acne-prone skin. While both brands feature botanical [extracts](https://lovi.care/skincare/nl/ingredients/extract), they differ as the Swiss line relies on gentle botanical bases, whereas the Spanish line combines botanical extracts and active compounds to refine skin texture and promote a radiant complexion.

Weleda is a Swiss skincare brand founded in 1921 and owned by Weleda AG.

[assets.weleda.com](https://assets.weleda.com/binaries/content/assets/pdf/fr/rapport-annuel/annual_sustainability_report_weleda_2022.pdf) [en.wikipedia.org](https://en.wikipedia.org/wiki/Weleda) [cosmeticsbusiness.com](https://cosmeticsbusiness.com/weleda-s-organisational-restructure-drove-record-turnover-in-2024)

Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.

[skinexpert.sesderma.com](https://skinexpert.sesderma.com/en/jb-capital-joins-the-shareholding-of-sesderma-group-as-a-strategic-partner/) [sesderma.com](https://www.sesderma.com/us_en/about-us.html)

This page compares some of the most popular Weleda and Sesderma products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg4c9183c01b).

### Popular Weleda vs Sesderma products

#### Sesderma

- [Azelac RU Serum](https://lovi.care/skincare/nl/p/sesderma/azelac-ru-serum/for/acne-prone-skin) — High fit — [€30.28 at Amazon](https://www.amazon.nl/dp/B00987RKWW?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)

#### Weleda

- [Skin Food](https://lovi.care/skincare/nl/p/weleda/skin-food/for/dry-skin) — High fit — [€8.98 at Amazon](https://www.amazon.nl/dp/B000ORV3NC?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Skin Food Light](https://lovi.care/skincare/nl/p/weleda/skin-food-light/for/dry-skin) — Average fit — [€7.14 at Amazon](https://www.amazon.nl/dp/B07JK519V7?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)

## Questions and answers

### Weleda or Sesderma: which is better?

Neither brand is universally better, as Weleda offers High fit for dry and dry sensitive skin with products like Skin Food, while Sesderma provides High fit for acne-prone skin and skin with dark spots using Azelac RU [Serum](https://lovi.care/skincare/nl/ingredients/serum).

### What is the difference between Weleda and Sesderma?

Weleda and Sesderma differ mainly in their origin and product focus, as Weleda is a Swiss brand offering rich moisturizers like Skin Food, while Sesderma is a Spanish brand featuring targeted treatments like Azelac RU Serum. Both brands include fragrance in the products on this page.

### Which is more affordable, Weleda or Sesderma?

I am sorry, but the provided page facts and studies do not contain pricing information to determine whether Weleda or Sesderma is more affordable.

### Which causes fewer breakouts, Weleda or Sesderma?

For acne-prone skin, Sesderma fits better with a High rating for Azelac RU Serum, while the Weleda products on this page get Low or Caution ratings.

### Which brand has been established longer, Weleda or Sesderma?

Weleda has been established longer, having been founded in Switzerland in 1921 compared to Sesderma, which was founded in Spain in 1989.

### Do any products from Weleda or Sesderma contain fragrance?

Yes, all the products on this page from both Weleda and Sesderma contain fragrance.

### Which brand offers a moisturizer suitable for dry skin with a High Lovi fit level?

Weleda offers a moisturizer suitable for dry skin with a High Lovi fit level through its Skin Food product. Sesderma does not feature a moisturizer for dry skin with a High fit on this page.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Nicotinic acid/niacinamide and the skin](https://pubmed.ncbi.nlm.nih.gov/17147561/) Niacin · Journal of Cosmetic Dermatology, 2004
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol · The British Journal of Dermatology, 2019
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [A topical lipophilic niacin derivative increases NAD, epidermal differentiation and barrier function in photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/17518989/) Niacin · Experimental Dermatology, 2007
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [A pilot randomized double-blind placebo-controlled trial on topical chamomile (Matricaria chamomilla L.) oil for severe carpal tunnel syndrome](https://pubmed.ncbi.nlm.nih.gov/26573447/) Chamomilla recutita flower extract matricaria flower extract · Complementary Therapies in Clinical Practice, 2015
- [Exotic Vegetable Oils for Cosmetic O/W Nanoemulsions: In Vivo Evaluation](https://pubmed.ncbi.nlm.nih.gov/26927034/) Lanolin · Molecules, 2016
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [The efficacy of enoxolone in reducing erythema and pain after laser treatment: A randomized split-face pilot study](https://pubmed.ncbi.nlm.nih.gov/38622995/) Glycyrrhetinic acid · Journal of Cosmetic Dermatology, 2024
- [Dermatological Effects of a Beeswax-Pine Resin Mixture on Abdominal Skin: A Proof-of-Concept Study Supporting the Development of an Affordable Investigational Ostomy Pouching System in Low-Income Regions](https://pubmed.ncbi.nlm.nih.gov/42758164/) Beeswax cera alba cera · Journal of Wound, Ostomy, and Continence Nursing, 2026

## The brands

- Swiss skincare: [Weleda](https://lovi.care/skincare/nl/brands/weleda)
- Spanish skincare: [Sesderma](https://lovi.care/skincare/nl/brands/sesderma)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

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