# Trilogy vs ISDIN Isdinceutics

Page: https://lovi.care/skincare/nl/compare/trilogy-vs-isdin-isdinceutics

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Trilogy and ISDIN Isdinceutics are distinct skincare labels celebrated for their effective formulations and thoughtful approach to daily maintenance. Trilogy is deeply loved for its thoughtful moisturizers and gentle cleansers, built on high-performing formulas that suit dry, balanced, and sensitive skin types best. Meanwhile, the Spanish brand ISDIN Isdinceutics is revered for its targeted eye products and advanced formulas tailored to mature, dry, and sensitive skin. While both share a gentle yet effective composition, they differ in their standout offerings, with the former addressing concerns like dark spots and mature skin, and the latter providing relief for dark circles, puffiness, and acne-prone skin.

ISDIN Isdinceutics is a Spanish skincare brand founded in 1975 and owned by Puig since 2027.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/)

This page compares some of the most popular Trilogy and ISDIN Isdinceutics products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pge7a110a830).

### Popular Trilogy vs ISDIN Isdinceutics products

#### ISDIN Isdinceutics

- [K-Ox Eyes](https://lovi.care/skincare/nl/p/isdin-isdinceutics/k-ox-eyes/for/dry-skin) — High fit

#### Trilogy

- [Rosehip Cream Cleanser](https://lovi.care/skincare/nl/p/trilogy/rosehip-cream-cleanser/for/sensitive-skin) — High fit
- [Line Smoothing Day Cream](https://lovi.care/skincare/nl/p/trilogy/line-smoothing-day-cream/for/dry-skin) — High fit
- [Vitamin C Ceramide Night Cream](https://lovi.care/skincare/nl/p/trilogy/vitamin-c-ceramide-night-cream/for/mature-skin) — High fit

## Questions and answers

### Trilogy or ISDIN Isdinceutics: which is better?

Trilogy has a High fit for dry skin, while ISDIN Isdinceutics has a High fit for dry skin and mature skin. Trilogy offers multiple products on this page with High fits for dry skin and skin with dark spots, though reviewers mostly mention product performance and formulation complaints.

### What is the difference between Trilogy and ISDIN Isdinceutics?

Trilogy offers a wider selection of products on this page, including cleansers and moisturizers, whereas ISDIN Isdinceutics features a specialized eye product. Reviewers mostly mention that Trilogy's moisturizers are hydrating and brightening, though there are also formulation complaints.

### Which is more affordable, Trilogy or ISDIN Isdinceutics?

Neither Trilogy nor ISDIN Isdinceutics is more affordable because pricing information is not available on this page.

### Which causes fewer breakouts, Trilogy or ISDIN Isdinceutics?

Neither brand has a dedicated anti-acne range on this page, but Trilogy offers products with High fit for dry and sensitive skin, while ISDIN Isdinceutics features an eye cream with High fit for mature skin.

### Between Trilogy and ISDIN Isdinceutics, which brand has been around longer?

ISDIN Isdinceutics has been around longer, having been founded in 1975 compared to Trilogy's founding in 2002.

### Which brand offers an eye product according to the page?

ISDIN Isdinceutics offers an eye product on this page with K-Ox Eyes, while Trilogy features cleansers and moisturizers instead.

### Which brand has products that include fragrance?

Both brands feature products on this page that contain fragrance, as Trilogy includes it in its cleanser and night cream, and ISDIN Isdinceutics includes it in its eye product.

## Research behind their key ingredients

- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Chrysin protects epidermal keratinocytes from UVA- and UVB-induced damage](https://pubmed.ncbi.nlm.nih.gov/21699266/) Chrysin · Journal of Agricultural and Food Chemistry, 2011
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Topical Almond Oil for Prevention of Pressure Injuries: A Single-Blinded Comparison Study](https://pubmed.ncbi.nlm.nih.gov/32379165/) Prunus amygdalus dulcis oil · Journal of Wound, Ostomy, and Continence Nursing, 2020
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Chitosan derivative nanocarrier: safety evaluation,antibacterial property and ascorbyl palmitate encapsulation](https://pubmed.ncbi.nlm.nih.gov/19566395/) Ascorbyl palmitate · Journal of Microencapsulation, 2010
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025
- [Monocentric, Vehicle-Controlled, Double-Blind Study to Assess the Short- and Long-Term Effects of a Ceramide NP C15-Containing Emollient on the Skin Microbiome and the Skin Barrier Function in Sensitive Skin](https://pubmed.ncbi.nlm.nih.gov/41758783/) Ceramide iii · Skin Pharmacology and Physiology, 2026
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026

## The brands

- Skincare: [Trilogy](https://lovi.care/skincare/nl/brands/trilogy)
- Spanish skincare: [ISDIN Isdinceutics](https://lovi.care/skincare/nl/brands/isdin-isdinceutics)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/trilogy-vs-isdin-isdinceutics
- United Kingdom: https://lovi.care/skincare/uk/compare/trilogy-vs-isdin-isdinceutics
- Ireland: https://lovi.care/skincare/ie/compare/trilogy-vs-isdin-isdinceutics
- Germany: https://lovi.care/skincare/de/compare/trilogy-vs-isdin-isdinceutics
- France: https://lovi.care/skincare/fr/compare/trilogy-vs-isdin-isdinceutics
- Italy: https://lovi.care/skincare/it/compare/trilogy-vs-isdin-isdinceutics
- Netherlands: https://lovi.care/skincare/nl/compare/trilogy-vs-isdin-isdinceutics (this page)
- Spain: https://lovi.care/skincare/es/compare/trilogy-vs-isdin-isdinceutics
- Canada: https://lovi.care/skincare/ca/compare/trilogy-vs-isdin-isdinceutics
- Australia: https://lovi.care/skincare/au/compare/trilogy-vs-isdin-isdinceutics
- Singapore: https://lovi.care/skincare/sg/compare/trilogy-vs-isdin-isdinceutics
- Saudi Arabia: https://lovi.care/skincare/sa/compare/trilogy-vs-isdin-isdinceutics
- United Arab Emirates: https://lovi.care/skincare/ae/compare/trilogy-vs-isdin-isdinceutics