Sesderma vs Endocare
Sesderma and Endocare are Spanish skincare brands offering advanced serums, nurturing moisturizers, and sophisticated formulas. Sesderma suits sensitive, hyperpigmented, and aging skin types best through products like the Azelac RU Serum, while Endocare suits mature and dry skin best through standout choices like the Tensage Cream. Both rely on botanical extracts, active compounds, and advanced scientific formulations to refine skin texture and promote a radiant complexion. Ultimately, these brands differ in their founding years, ownership, and target skin concerns.
Sesderma is a Spanish skincare brand founded in 1989 and owned by Grupo Sesderma since 2026.
skinexpert.sesderma.comsesderma.com
Endocare is a Spanish skincare brand founded in 1996 and owned by Cantabria Labs.
This page compares some of the most popular Sesderma and Endocare products; for every product of both brands, with a fit score for your own skin, use the Lovi app.
Questions and answers
Sesderma or Endocare: which is better?
Neither brand is universally better, as Sesderma achieves a High fit for acne-prone skin and dark spots with its Azelac RU Serum, while Endocare avoids fragrance across the products on this page and achieves an Average fit for mature skin.
What is the difference between Sesderma and Endocare?
Sesderma offers the products on this page with fragrance, whereas every Endocare product on this page lists no fragrance. For dark spots, Sesderma Azelac RU Serum has a High Lovi fit, while Endocare Tensage Cream has an Average fit.
Which is more affordable, Sesderma or Endocare?
I am sorry, but the provided page facts and studies do not contain pricing or affordability information for either Sesderma or Endocare.
Which causes fewer breakouts, Sesderma or Endocare?
Endocare products on this page are unlikely to suit breakout-prone skin well, as Tensage Cream has a Low fit for acne-prone skin and Caution for oily or combination skin. Sesderma's Azelac RU Serum helps with acne-prone skin with a High fit.
Which brand was founded earlier, Sesderma or Endocare?
Sesderma was founded earlier in 1989, while Endocare was founded in 1996.
Do products from Sesderma or Endocare contain fragrance?
For the products on this page, Sesderma includes fragrance in its Azelac RU Serum, while Endocare lists no fragrance in the ingredients for any of its products.
Which company currently owns Sesderma?
Grupo Sesderma currently owns Sesderma.
Research behind their key ingredients
The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer
Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo
Behind this comparison
Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
-

Co-founder, Medical Director
Cosmetic chemist, cosmetologist, aesthetic products developer
-

Co-founder, CEO and CTO
PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
-

Dr. Sofía Perea Pérez, MD, MSc
Medical Board
Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine
-

Medical Board
Specialist dermatologist, MBBS, MD, IFAAD
-

Medical Board
Cosmetic chemist, SCS, IFSCC member
-

Medical Board, Medical Advisor
Dermatology MD
-

Elina Nazarenko, MD
Medical Board
Dermatology and diagnostic consultant
-

Victoria Derkova, MS
Medical Board
Cosmetic chemist, cosmetic development technologist
How does it fit your skin?
Scan your face, then any product: Lovi shows how well it fits you and what fits even better.


