# Paula's Choice vs Shiseido

Page: https://lovi.care/skincare/nl/compare/paula-s-choice-vs-shiseido

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Paula's Choice and Shiseido are prominent skincare brands offering [serums](https://lovi.care/skincare/nl/ingredients/serum), cleansers, moisturizers, toners, and sunscreens. Paula's Choice is an American line known for formulas built around [hyaluronic acid](https://lovi.care/skincare/nl/ingredients/hyaluronic-acid), [glycerin](https://lovi.care/skincare/nl/ingredients/glycerin), and [vitamin c](https://lovi.care/skincare/nl/ingredients/vitamin-c), suiting acne-prone skin and oily skin best. Shiseido is a Japanese brand beloved for daily care formulated with key ingredients like glycerin, suiting sensitive skin and mature skin best. Both utilize glycerin, which clinical study findings show significantly increases skin hydration and restores barrier function, though they differ in their specific ingredient focus and heritage.

Paula's Choice is an American skincare brand founded in 1995 and owned by Unilever since 2021.

[unilever.com](https://www.unilever.com/news/press-and-media/press-releases/2021/unilever-to-acquire-paulas-choice-skincare/) [tracxn.com](https://tracxn.com/d/companies/paulas-choice/__3NzlGcC2yhs-Z9XjkOCar6Dxe0DJgowfl0PAX9OD5s8)

Shiseido is a Japanese skincare brand founded in 1872 and owned by Shiseido Company, Limited.

[corp.shiseido.com](https://corp.shiseido.com/en/company/info/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Shiseido) [marketscreener.com](https://www.marketscreener.com/quote/stock/SHISEIDO-COMPANY-LIMITED-6492328/news/Shiseido-Company-Limited-Announces-CEO-Changes-Effective-January-1-2025-47501230/)

This page compares some of the most popular Paula's Choice and Shiseido products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg06946ed220).

### Popular Paula's Choice vs Shiseido products

#### Paula's Choice

- [Skin Perfecting 2% BHA Liquid Exfoliant](https://lovi.care/skincare/nl/p/paula-s-choice/skin-perfecting-2-bha-liquid-exfoliant/for/oily-skin) — Superior fit — [€14.00 at Amazon](https://www.amazon.nl/dp/B07PQSRXR6?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [1% Retinol Treatment](https://lovi.care/skincare/nl/p/paula-s-choice/1-retinol-treatment/for/dark-spots) — Superior fit — [€57.00 at Amazon](https://www.amazon.nl/dp/B07P6M914G?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [10% Azelaic Acid Booster](https://lovi.care/skincare/nl/p/paula-s-choice/10-azelaic-acid-booster/for/acne-prone-skin) — High fit — [€49.00 at Amazon](https://www.amazon.nl/dp/B09S9R72XB?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [C15 Super Booster](https://lovi.care/skincare/nl/p/paula-s-choice/c15-super-booster/for/mature-skin) — High fit — [€65.00 at Amazon](https://www.amazon.nl/dp/B0H9975SCY?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/nl/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-acne-prone-skin) — Superior fit — [€29.00 at Amazon](https://www.amazon.nl/dp/B0D9Q99LKF?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [10% Niacinamide Booster](https://lovi.care/skincare/nl/p/paula-s-choice/10-niacinamide-booster/for/dry-sensitive-skin) — Superior fit — [€59.00 at Amazon](https://www.amazon.nl/dp/B07QCWTYJ2?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Weightless Body Treatment 2% BHA](https://lovi.care/skincare/nl/p/paula-s-choice/weightless-body-treatment-2-bha/for/oily-acne-prone-skin) — Average fit — [€39.00 at Amazon](https://www.amazon.nl/dp/B07TJRGDYC?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [€36.00 at Amazon](https://www.amazon.nl/dp/B07P7VZ2J9?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)

#### Shiseido

- [Benefiance Wrinkle Smoothing Eye Cream](https://lovi.care/skincare/nl/p/shiseido/benefiance-wrinkle-smoothing-eye-cream/for/mature-skin) — High fit — [€67.95 at Amazon](https://www.amazon.nl/dp/B07MZ7MJJ8?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/nl/p/shiseido/ultimune-power-infusing-concentrate/for/sensitive-skin) — Average fit — [€59.47 at Amazon](https://www.amazon.nl/dp/B0F5YYYNGW?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [VITAL PERFECTION](https://lovi.care/skincare/nl/p/shiseido/vital-perfection/for/mature-skin) — Average fit — [€69.33 at Amazon](https://www.amazon.nl/dp/B0CP67VGG7?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Clarifying Cleansing Foam](https://lovi.care/skincare/nl/p/shiseido/clarifying-cleansing-foam/for/mature-skin) — Average fit — [€35.00 at Amazon](https://www.amazon.nl/dp/B07HYRFVX7?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Essential Energy Hydrating Cream](https://lovi.care/skincare/nl/p/shiseido/essential-energy-hydrating-cream/for/mature-skin) — Superior fit — [€37.54 at Amazon](https://www.amazon.nl/dp/B09SBSPXTY?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Activating Essence](https://lovi.care/skincare/nl/p/shiseido/activating-essence/for/dry-skin) — High fit
- [FUTURE SOLUTION LX](https://lovi.care/skincare/nl/p/shiseido/future-solution-lx/for/sensitive-skin) — High fit
- [Bio-Performance Advanced Super Revitalizing Cream](https://lovi.care/skincare/nl/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/dry-skin) — Warning fit — [€51.99 at Amazon](https://www.amazon.nl/dp/B0092LG0SE?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)

## People Say

Paula's Choice

Shiseido

- Deep hydration and moisture Not noted Mostly Mentioned “Immediate sensation of comfort — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “skin feels plump, soft and nourished, eliminates dryness, bouncy feel — Shiseido VITAL PERFECTION” “Skin feels more hydrated — Shiseido Activating Essence”
- Lightweight and fast absorbing formulas Mostly Mentioned Often Mentioned “Absorbs quickly and leaves no greasy residue behind. — Paula's Choice Clear Oil-Free Moisturizer” “absorbs instantly — Paula's Choice C15 Super Booster” “Lightweight, silky, non-sticky, sinks in instantly. — Shiseido Ultimune Power Infusing Concentrate” “Airy-soft texture — Shiseido Essential Energy Hydrating Cream”
- Smooth texture and skin softening Mostly Mentioned Often Mentioned “skin becomes very smooth — Paula's Choice 1% Retinol Treatment” “skin is insanely soft — Paula's Choice Weightless Body Treatment 2% BHA” “skin never been this silky — Paula's Choice Skin-Smoothing Retinol Body Treatment” “Velvety smooth — Shiseido FUTURE SOLUTION LX”
- Brightening and radiance Sometimes Noted Often Mentioned “Skin looks brighter, more radiant, and "glowy." — Shiseido Ultimune Power Infusing Concentrate” “faded pimple marks — Shiseido White Lucent Brightening Gel Cream” “Eyes look more awake — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “visible glow — Paula's Choice C15 Super Booster”
- Acne clearing and pore control Mostly Mentioned Not noted “cleared my bumps — Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant” “Helped clear my cystic acne — Paula's Choice CLEAR Pore Normalizing Cleanser” “pores look smaller — Paula's Choice 10% Niacinamide Booster”
- Luxurious and elegant texture Not noted Often Mentioned “silky smooth, rich but non-greasy, absorbs quickly, melts into skin — Shiseido VITAL PERFECTION” “Velvety, rich cream texture — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “Velvety texture — Shiseido FUTURE SOLUTION LX”
- High price point and expensive Mostly Mentioned Mostly Mentioned “tiny tube — Paula's Choice 10% Azelaic Acid Booster” “Sooooo expensive — Paula's Choice 25% Vitamin C + Glutathione Clinical Serum” “Very expensive for the size — Shiseido Benefiance Wrinkle Smoothing Eye Cream” “Expensive, pricey, high cost for the amount. — Shiseido Ultimune Power Infusing Concentrate”
- Strong fragrance and scent issues Often Mentioned Often Mentioned “smells like grain — Paula's Choice 10% Azelaic Acid Booster” “smells like hot dog water — Paula's Choice C15 Super Booster” “weird glue-like smell — Paula's Choice Weightless Body Treatment 2% BHA” “old lady smell — Shiseido Eudermine Revitalizing Essence”
- Packaging problems and design issues Sometimes Noted Sometimes Noted “dropper leaks — Paula's Choice C15 Super Booster” “dropper can be unpredictable — Paula's Choice Pro-Collagen Multi-Peptide Booster” “heavy to travel — Shiseido Eudermine Revitalizing Essence” “Heavy bottle but plastic pump, cannot see remaining product, straw too short to get last drops. — Shiseido Ultimune Power Infusing Concentrate”
- Skin irritation and burning Rarely Noted Sometimes Noted “burnt skin off — Paula's Choice 1% Retinol Treatment” “ruined my skin barrier — Paula's Choice Skin Perfecting 2% BHA Liquid Exfoliant” “stung my face — Paula's Choice 10% Azelaic Acid Booster” “Caused some irritation — Shiseido Bio-Performance Advanced Super Revitalizing Cream”

### Paula's Choice vs Shiseido routines for dry skin

#### Paula's Choice-focused routine

- Cleanser: [CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/nl/p/paula-s-choice/clear-pore-normalizing-cleanser/for/dry-skin) — Caution fit — [€29.00 at Amazon](https://www.amazon.nl/dp/B0D9Q99LKF?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Advanced Replenishing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/advanced-replenishing-toner/for/dry-skin) — Superior fit — [€34.00 at Amazon](https://www.amazon.nl/dp/B07P57D5SX?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [RESIST Intensive Wrinkle-Repair Retinol Serum](https://lovi.care/skincare/nl/p/paula-s-choice/resist-intensive-wrinkle-repair-retinol-serum/for/dry-skin) — Caution fit — [€57.00 at Amazon](https://www.amazon.nl/dp/B07P6M914G?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Youth-Extending Daily Hydrating Fluid SPF 50](https://lovi.care/skincare/nl/p/paula-s-choice/youth-extending-daily-hydrating-fluid-spf-50/for/dry-skin) — High fit — [€47.00 at Amazon](https://www.amazon.nl/dp/B07P5SRJ4H?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [ROUND LAB 1025 Dokdo Cleansing Water](https://lovi.care/skincare/nl/p/round-lab/1025-dokdo-cleansing-water/for/dry-skin) — Superior fit — [€13.99 at Amazon](https://www.amazon.nl/dp/B0BPB4KMJP?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Pro-Collagen Multi-Peptide Booster](https://lovi.care/skincare/nl/p/paula-s-choice/pro-collagen-multi-peptide-booster/for/dry-skin) — Superior fit — [€65.00 at Amazon](https://www.amazon.nl/dp/B0C5J46GVN?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [LANEIGE Water Sleeping Mask_EX](https://lovi.care/skincare/nl/p/laneige/water-sleeping-mask-ex/for/dry-skin) — Superior fit — [€33.90 at Amazon](https://www.amazon.nl/dp/B07XFLXW3S?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

#### Shiseido-focused routine

- Cleanser: [Clarifying Cleansing Foam](https://lovi.care/skincare/nl/p/shiseido/clarifying-cleansing-foam/for/dry-skin) — Caution fit — [€35.00 at Amazon](https://www.amazon.nl/dp/B07HYRFVX7?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Eudermine Revitalizing Essence](https://lovi.care/skincare/nl/p/shiseido/eudermine-revitalizing-essence/for/dry-skin) — Average fit — [€37.90 at Notino](https://www.notino.nl/shiseido/eudermine-activating-essence-revitaliserende-tonic-met-hydraterende-werking/p-16178706/) — Morning
- Moisturizer: [Essential Energy Hydrating Cream](https://lovi.care/skincare/nl/p/shiseido/essential-energy-hydrating-cream/for/dry-skin) — High fit — [€37.54 at Amazon](https://www.amazon.nl/dp/B09SBSPXTY?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Purito Daily Soft Touch Sunscreen](https://lovi.care/skincare/nl/p/purito/daily-soft-touch-sunscreen/for/dry-skin) — Superior fit — [€20.01 at Amazon](https://www.amazon.nl/dp/B0BS21D6SW?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [ROUND LAB 1025 Dokdo Cleansing Water](https://lovi.care/skincare/nl/p/round-lab/1025-dokdo-cleansing-water/for/dry-skin) — Superior fit — [€13.99 at Amazon](https://www.amazon.nl/dp/B0BPB4KMJP?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/nl/p/shiseido/ultimune-power-infusing-concentrate/for/dry-skin) — Low fit — [€59.47 at Amazon](https://www.amazon.nl/dp/B0F5YYYNGW?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [LANEIGE Water Sleeping Mask_EX](https://lovi.care/skincare/nl/p/laneige/water-sleeping-mask-ex/for/dry-skin) — Superior fit — [€33.90 at Amazon](https://www.amazon.nl/dp/B07XFLXW3S?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 98% fit](https://lovi.care/skincare/nl/skin/dry-skin)

### Paula's Choice vs Shiseido routines for oily skin

#### Paula's Choice-focused routine

- Cleanser: [CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/nl/p/paula-s-choice/clear-pore-normalizing-cleanser/for/oily-skin) — Superior fit — [€29.00 at Amazon](https://www.amazon.nl/dp/B0D9Q99LKF?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Advanced Replenishing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/advanced-replenishing-toner/for/oily-skin) — High fit — [€34.00 at Amazon](https://www.amazon.nl/dp/B07P57D5SX?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Clear Oil-Free Moisturizer](https://lovi.care/skincare/nl/p/paula-s-choice/clear-oil-free-moisturizer/for/oily-skin) — High fit — [€42.00 at Amazon](https://www.amazon.nl/dp/B07SC3JQ9M?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Youth-Extending Daily Hydrating Fluid SPF 50](https://lovi.care/skincare/nl/p/paula-s-choice/youth-extending-daily-hydrating-fluid-spf-50/for/oily-skin) — Average fit — [€47.00 at Amazon](https://www.amazon.nl/dp/B07P5SRJ4H?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/oily-skin) — High fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/nl/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [€18.05 at Amazon](https://www.amazon.nl/dp/B09SN5B88W?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Niacinamide 20% Treatment](https://lovi.care/skincare/nl/p/paula-s-choice/niacinamide-20-treatment/for/oily-skin) — Superior fit — [€63.00 at Amazon](https://www.amazon.nl/dp/B08SW6VPJL?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/nl/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€72.82 at Amazon](https://www.amazon.nl/dp/B0D1YJN279?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/nl/p/vt-cosmetics/cica-purifying-mask/for/oily-skin) — High fit — [€15.72 at Amazon](https://www.amazon.nl/dp/B083X5R6VR?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

#### Shiseido-focused routine

- Cleanser: [Deep Cleansing Foam](https://lovi.care/skincare/nl/p/shiseido/deep-cleansing-foam/for/oily-skin) — High fit — [€37.00 at Amazon](https://www.amazon.nl/dp/B07HYQXNKF?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Eudermine Revitalizing Essence](https://lovi.care/skincare/nl/p/shiseido/eudermine-revitalizing-essence/for/oily-skin) — Average fit — [€37.90 at Notino](https://www.notino.nl/shiseido/eudermine-activating-essence-revitaliserende-tonic-met-hydraterende-werking/p-16178706/) — Morning · Once a week
- Moisturizer: [Essential Energy Hydrating Cream](https://lovi.care/skincare/nl/p/shiseido/essential-energy-hydrating-cream/for/oily-skin) — Average fit — [€37.54 at Amazon](https://www.amazon.nl/dp/B09SBSPXTY?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — [€33.70 at Amazon](https://www.amazon.nl/dp/B0CF22FB86?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/oily-skin) — High fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/nl/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [€18.05 at Amazon](https://www.amazon.nl/dp/B09SN5B88W?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/nl/p/shiseido/ultimune-power-infusing-concentrate/for/oily-skin) — Average fit — [€59.47 at Amazon](https://www.amazon.nl/dp/B0F5YYYNGW?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/nl/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€72.82 at Amazon](https://www.amazon.nl/dp/B0D1YJN279?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/nl/p/vt-cosmetics/cica-purifying-mask/for/oily-skin) — High fit — [€15.72 at Amazon](https://www.amazon.nl/dp/B083X5R6VR?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 95% fit](https://lovi.care/skincare/nl/skin/oily-skin)

### Paula's Choice vs Shiseido routines for combination skin

#### Paula's Choice-focused routine

- Cleanser: [CLEAR Pore Normalizing Cleanser](https://lovi.care/skincare/nl/p/paula-s-choice/clear-pore-normalizing-cleanser/for/combination-skin) — Superior fit — [€29.00 at Amazon](https://www.amazon.nl/dp/B0D9Q99LKF?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Advanced Replenishing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/advanced-replenishing-toner/for/combination-skin) — High fit — [€34.00 at Amazon](https://www.amazon.nl/dp/B07P57D5SX?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Clear Oil-Free Moisturizer](https://lovi.care/skincare/nl/p/paula-s-choice/clear-oil-free-moisturizer/for/combination-skin) — Average fit — [€42.00 at Amazon](https://www.amazon.nl/dp/B07SC3JQ9M?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Youth-Extending Daily Hydrating Fluid SPF 50](https://lovi.care/skincare/nl/p/paula-s-choice/youth-extending-daily-hydrating-fluid-spf-50/for/combination-skin) — High fit — [€47.00 at Amazon](https://www.amazon.nl/dp/B07P5SRJ4H?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/combination-skin) — Superior fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/nl/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [€16.99 at Amazon](https://www.amazon.nl/dp/B09V7Z4TJG?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Niacinamide 20% Treatment](https://lovi.care/skincare/nl/p/paula-s-choice/niacinamide-20-treatment/for/combination-skin) — Superior fit — [€63.00 at Amazon](https://www.amazon.nl/dp/B08SW6VPJL?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/nl/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — [€15.72 at Amazon](https://www.amazon.nl/dp/B083X5R6VR?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

#### Shiseido-focused routine

- Cleanser: [Deep Cleansing Foam](https://lovi.care/skincare/nl/p/shiseido/deep-cleansing-foam/for/combination-skin) — High fit — [€37.00 at Amazon](https://www.amazon.nl/dp/B07HYQXNKF?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Eudermine Revitalizing Essence](https://lovi.care/skincare/nl/p/shiseido/eudermine-revitalizing-essence/for/combination-skin) — High fit — [€37.90 at Notino](https://www.notino.nl/shiseido/eudermine-activating-essence-revitaliserende-tonic-met-hydraterende-werking/p-16178706/) — Morning · Once a week
- Moisturizer: [Essential Energy Hydrating Cream](https://lovi.care/skincare/nl/p/shiseido/essential-energy-hydrating-cream/for/combination-skin) — Average fit — [€37.54 at Amazon](https://www.amazon.nl/dp/B09SBSPXTY?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — [€33.70 at Amazon](https://www.amazon.nl/dp/B0CF22FB86?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/combination-skin) — Superior fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/nl/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [€16.99 at Amazon](https://www.amazon.nl/dp/B09V7Z4TJG?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Ultimune Power Infusing Concentrate](https://lovi.care/skincare/nl/p/shiseido/ultimune-power-infusing-concentrate/for/combination-skin) — Average fit — [€59.47 at Amazon](https://www.amazon.nl/dp/B0F5YYYNGW?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/nl/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — [€15.72 at Amazon](https://www.amazon.nl/dp/B083X5R6VR?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 94% fit](https://lovi.care/skincare/nl/skin/combination-skin)

## Questions and answers

### Paula's Choice or Shiseido: which is better?

Paula's Choice is better for acne clearing and pore control as well as smooth texture and skin softening, whereas Shiseido is better for deep hydration and moisture, brightening and radiance, and luxurious and elegant texture. Both brands have equal routine fit levels for dry, oily, combination, sensitive, acne-prone, mature, and dark spot-prone skin, but Shiseido offers a high fit for dry sensitive skin while Paula's Choice is average.

### What is the difference between Paula's Choice and Shiseido?

Paula's Choice focuses on fragrance-free formulations that help with acne clearing and pore control, whereas Shiseido tends to offer luxurious textures and deep hydration while frequently containing added fragrance.

### Paula's Choice or Shiseido for dry skin?

Both Paula's Choice and Shiseido offer a High routine fit for dry skin, so either brand helps provide good moisture. Paula's Choice features fragrance-free formulas with key ingredients like [hyaluronic acid](https://lovi.care/skincare/nl/ingredients/hyaluronic-acid) and [glycerin](https://lovi.care/skincare/nl/ingredients/glycerin) across the products on this page, whereas Shiseido often includes fragrance while delivering deep hydration.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Paula's Choice or Shiseido: which cleanser is better?

Both Paula's Choice and Shiseido offer highly rated cleansers, but Paula's Choice is better suited for acne-prone skin while Shiseido excels in deep cleansing. Paula's Choice products on this page contain no fragrance, making them a gentler choice, whereas many Shiseido cleansers feature strong fragrances.

### Which is more affordable, Paula's Choice or Shiseido?

Both Paula's Choice and Shiseido share a high price point, so neither brand stands out as more affordable.

### Between Paula's Choice and Shiseido, which brand does better for deep hydration and moisture?

Shiseido does better than Paula's Choice for deep hydration and moisture. The products on this page help deliver deep hydration with a focus on luxurious textures and radiant skin.

### Which brand has a stronger fragrance or scent issues when comparing Paula's Choice and Shiseido?

Shiseido is often noted by reviewers for having a strong fragrance and scent issues, whereas Paula's Choice lists no fragrance across the products on this page.

### How do Paula's Choice and Shiseido compare in routine fit for dry sensitive skin?

Shiseido is a High fit for dry sensitive skin, whereas Paula's Choice is an Average fit.

### Paula's Choice or Shiseido for oily skin?

Both Paula's Choice and Shiseido offer a High routine fit for oily skin. Paula's Choice focuses on fragrance-free formulas with active ingredients like [salicylic acid](https://lovi.care/skincare/nl/ingredients/salicylic-acid) and [niacinamide](https://lovi.care/skincare/nl/ingredients/niacinamide) to help with pore control and acne clearing. Shiseido provides options with luxurious textures that help deliver deep hydration and radiance, though many of its products on this page contain added fragrance.

### Paula's Choice or Shiseido: which moisturizer is better?

Both brands offer moisturizers with high fit levels, but Shiseido excels in providing deep hydration and luxurious textures while Paula's Choice features fragrance-free options. The products on this page help improve skin texture and moisture levels.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Paula's Choice or Shiseido for sensitive skin?

Both Paula's Choice and Shiseido offer a High routine fit for sensitive skin. Paula's Choice features fragrance-free formulas across all the products on this page, whereas many Shiseido products contain added fragrance.

### Paula's Choice or Shiseido: which sunscreen is better?

Paula's Choice sunscreen is better for fragrance-sensitive users because every product on its page lists no fragrance, whereas most Shiseido sunscreens contain fragrance. Both brands offer solid options depending on your skin type, with Shiseido's Benefiance Wrinkle Smoothing Day Cream achieving a Superior fit for mature and sensitive skin.

### Paula's Choice or Shiseido for acne-prone skin?

Both Paula's Choice and Shiseido offer a high routine fit for acne-prone skin. Paula's Choice stands out for acne clearing and pore control, with every product on the page listing no fragrance.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Sodium hyaluronate · Drug Delivery, 2017
- [Green tea polyphenol (-)-epigallocatechin-3-gallate treatment of human skin inhibits ultraviolet radiation-induced oxidative stress](https://pubmed.ncbi.nlm.nih.gov/11181450/) Epigallocatechin gallate · Carcinogenesis, 2001
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Formation and stability of oil-in-water nanoemulsions containing rice bran oil: in vitro and in vivo assessments](https://pubmed.ncbi.nlm.nih.gov/21952107/) Rice bran oil · Journal of Nanobiotechnology, 2011
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002
- [Caffeine's mechanisms of action and its cosmetic use](https://pubmed.ncbi.nlm.nih.gov/23075568/) Caffeine · Skin Pharmacology and Physiology, 2013
- [Epigallocatechin-3-gallate improves acne in humans by modulating intracellular molecular targets and inhibiting P. acnes](https://pubmed.ncbi.nlm.nih.gov/23096708/) Epigallocatechin gallate · The Journal of Investigative Dermatology, 2013
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Peroxidated squalene induces the production of inflammatory mediators in HaCaT keratinocytes: a possible role in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/16778793/) Squalane · The Journal of Investigative Dermatology, 2006
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol · Journal of Cosmetic Dermatology, 2020
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Psychophysical study of the effects of topical application of menthol in healthy volunteers](https://pubmed.ncbi.nlm.nih.gov/16527405/) Menthol · Pain, 2006
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol, Bakuchiol · The British Journal of Dermatology, 2019
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Ascorbyl glucoside · Journal of Periodontology, 2009
- [Evaluation of efficacy and tolerance of a nighttime topical antioxidant containing resveratrol, baicalin, and vitamin e for treatment of mild to moderately photodamaged skin](https://pubmed.ncbi.nlm.nih.gov/25607790/) Scutellaria baicalensis root extract · Journal of Drugs in Dermatology, 2014
- [Ethanol extracts of Sanguisorba officinalis L. suppress TNF-α/IFN-γ-induced pro-inflammatory chemokine production in HaCaT cells](https://pubmed.ncbi.nlm.nih.gov/26655409/) Sanguisorba officinalis root extract · Phytomedicine, 2015
- [Skin-whitening and skin-condition-improving effects of topical oxidized glutathione: a double-blind and placebo-controlled clinical trial in healthy women](https://pubmed.ncbi.nlm.nih.gov/25378941/) Glutathione · Clinical, Cosmetic and Investigational Dermatology, 2014
- [Skin barrier disruption by sodium lauryl sulfate-exposure alters the expressions of involucrin, transglutaminase 1, profilaggrin, and kallikreins during the repair phase in human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/18007579/) Sodium lauryl sulfate · The Journal of Investigative Dermatology, 2008
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [Panax ginseng induces human Type I collagen synthesis through activation of Smad signaling](https://pubmed.ncbi.nlm.nih.gov/16890388/) Panax ginseng root extract · Journal of Ethnopharmacology, 2007
- [Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects](https://pubmed.ncbi.nlm.nih.gov/26648450/) Ubiquinone · BioFactors, 2015
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [A Double-Blind, Randomized Trial Shows the Role of Zonal Priming and Direct Topical Application of Epigallocatechin-3-Gallate in the Modulation of Cutaneous Scarring in Human Skin](https://pubmed.ncbi.nlm.nih.gov/30822414/) Epigallocatechin gallate · The Journal of Investigative Dermatology, 2019
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramides · Scientific Reports, 2022
- [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide · The Cochrane Database of Systematic Reviews, 2020
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ferulic acid, Tocopherol, Ascorbic acid, Tocopherol vitamin e · Journal of Cosmetic Dermatology, 2020
- [Licochalcone A activates Nrf2 in vitro and contributes to licorice extract-induced lowered cutaneous oxidative stress in vivo](https://pubmed.ncbi.nlm.nih.gov/25381913/) Licorice root extract, Glycyrrhiza glabra root extract licorice root extract · Experimental Dermatology, 2015
- [Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study](https://pubmed.ncbi.nlm.nih.gov/34211271/) Retinyl palmitate · International Journal of Nanomedicine, 2021
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [A review of topical high-concentration L-menthol as a translational model of cold allodynia and hyperalgesia](https://pubmed.ncbi.nlm.nih.gov/23963768/) Menthol · European Journal of Pain, 2014
- [Design, preparation, and evaluation of liposomal gel formulations for treatment of acne: in vitro and in vivo studies](https://pubmed.ncbi.nlm.nih.gov/30442066/) Lauric acid · Drug Development and Industrial Pharmacy, 2019
- [The clinical effect of glutathione on skin color and other related skin conditions: A systematic review](https://pubmed.ncbi.nlm.nih.gov/30895708/) Glutathione · Journal of Cosmetic Dermatology, 2019
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide · Journal of Shoulder and Elbow Surgery, 2021
- [Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial](https://pubmed.ncbi.nlm.nih.gov/19845667/) Acetyl glucosamine · The British Journal of Dermatology, 2010
- [Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine](https://pubmed.ncbi.nlm.nih.gov/17348991/) Acetyl glucosamine · Journal of Cosmetic Dermatology, 2007
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide · American Journal of Clinical Dermatology, 2022
- [In vitro antioxidant, collagenase inhibition, and in vivo anti-wrinkle effects of combined formulation containing Punica granatum, Ginkgo biloba, Ficus carica, and Morus alba fruits extract](https://pubmed.ncbi.nlm.nih.gov/26203268/) Ginkgo biloba leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2015
- [A randomized, controlled comparative study of the wrinkle reduction benefits of a cosmetic niacinamide/peptide/retinyl propionate product regimen vs. a prescription 0.02% tretinoin product regimen](https://pubmed.ncbi.nlm.nih.gov/20374604/) Retinyl propionate · The British Journal of Dermatology, 2010
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid, Salicylic acid bha · BioMed Research International, 2020
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, Panthenol vitamin b5 · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant](https://pubmed.ncbi.nlm.nih.gov/31130869/) Caffeine · Frontiers in Physiology, 2019
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin, Panthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [Topical glutathione amino acid precursors protect skin against environmental and oxidative stress](https://pubmed.ncbi.nlm.nih.gov/38189670/) Glutathione · Journal of the European Academy of Dermatology and Venereology, 2024
- [An Open-Label Single-Arm, Monocentric Study Assessing the Efficacy and Safety of Natural Pterostilbene (Pterocarpus marsupium) for Skin Brightening and Antiaging Effects](https://pubmed.ncbi.nlm.nih.gov/32099438/) Blueberry fruit extract · Clinical, Cosmetic and Investigational Dermatology, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf extract · Phytochemistry, 2001
- [In vivo skin irritation potential of a Castanea sativa (Chestnut) leaf extract, a putative natural antioxidant for topical application](https://pubmed.ncbi.nlm.nih.gov/18793273/) Chestnut leaf extract · Basic & Clinical Pharmacology & Toxicology, 2008
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid, Salicylic acid bha · Journal of Cosmetic Dermatology, 2024
- [Clinical evaluation of photoprotective effect by a topical antioxidants combination (tocopherols and tocotrienols)](https://pubmed.ncbi.nlm.nih.gov/21917024/) Tocotrienols · Journal of the European Academy of Dermatology and Venereology, 2012
- [Tocotrienol-rich fraction attenuates UV-induced inflammaging: A bench to bedside study](https://pubmed.ncbi.nlm.nih.gov/28952200/) Tocotrienols · Journal of Cosmetic Dermatology, 2018
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [Efficacy and Tolerability of a Skin Brightening/Anti-Aging Cosmeceutical Containing Retinol 0.5%, Niacinamide, Hexylresorcinol, and Resveratrol](https://pubmed.ncbi.nlm.nih.gov/27391637/) Hexylresorcinol · Journal of Drugs in Dermatology, 2016
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2015
- [Changes in Skin Barrier Function after Repeated Exposition to Phospholipid-Based Surfactants and Sodium Dodecyl Sulfate In Vivo and Corneocyte Surface Analysis by Atomic Force Microscopy](https://pubmed.ncbi.nlm.nih.gov/33804924/) Sodium lauryl sulfate · Pharmaceutics, 2021
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid, Salicylic acid bha · Journal of Drugs in Dermatology, 2023
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide · Journal of the American Academy of Dermatology, 2023
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide](https://pubmed.ncbi.nlm.nih.gov/34958693/) Hexylresorcinol · International Journal of Cosmetic Science, 2022
- [Chemical peels for acne vulgaris: a systematic review of randomised controlled trials](https://pubmed.ncbi.nlm.nih.gov/29705755/) Mandelic acid · BMJ Open, 2018
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release](https://pubmed.ncbi.nlm.nih.gov/35929319/) Oenothera biennis oil · Biomaterials Advances, 2022
- [A novel model of inflammatory pain in human skin involving topical application of sodium lauryl sulfate](https://pubmed.ncbi.nlm.nih.gov/20358390/) Sodium lauryl sulfate · Inflammation Research, 2010
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study](https://pubmed.ncbi.nlm.nih.gov/36729399/) Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Is benzyl alcohol a significant contact sensitizer?](https://pubmed.ncbi.nlm.nih.gov/35080274/) Benzyl alcohol · Journal of the European Academy of Dermatology and Venereology, 2022
- [Inhibitory effects of shell of Camellia oleifera Abel extract on mushroom tyrosinase and human skin melanin](https://pubmed.ncbi.nlm.nih.gov/31033161/) Butylene glycol · Journal of Cosmetic Dermatology, 2019
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow bark extract · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow bark extract · Planta Medica, 2019
- [Apple Extract (Malus sp.) and Rutin as Photochemopreventive Agents: Evaluation of Ultraviolet B-Induced Alterations on Skin Biopsies and Tissue-Engineered Skin](https://pubmed.ncbi.nlm.nih.gov/32242497/) Pyrus malus fruit extract · Rejuvenation Research, 2020
- [Administration of skin care regimens containing β-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study](https://pubmed.ncbi.nlm.nih.gov/33128496/) Beta-glucan · Journal of Cosmetic Dermatology, 2021
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [In vivo and in vitro evaluation of octyl methoxycinnamate liposomes](https://pubmed.ncbi.nlm.nih.gov/24376350/) Ethylhexyl methoxycinnamate · International Journal of Nanomedicine, 2013
- [A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/32390309/) Lauric acid · Dermatologic Therapy, 2020
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [The impacts of sodium lauroyl sarcosinate in facial cleanser on facial skin microbiome and lipidome](https://pubmed.ncbi.nlm.nih.gov/37990616/) Sodium lauroyl sarcosinate · Journal of Cosmetic Dermatology, 2024
- [Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine](https://pubmed.ncbi.nlm.nih.gov/28101465/) Acetyl glucosamine · Advanced Pharmaceutical Bulletin, 2016
- [Repair of acetone- and sodium lauryl sulphate-damaged human skin barrier function using topically applied emulsions containing barrier lipids](https://pubmed.ncbi.nlm.nih.gov/12482041/) Phytosphingosine · Journal of the European Academy of Dermatology and Venereology, 2002
- [Stability, antioxidant activity, in vivo safety and efficacy of creams with standardized wild apple fruit extract: a comparison of conventional and biodegradable emulsifiers](https://pubmed.ncbi.nlm.nih.gov/31050807/) Pyrus malus fruit extract · International Journal of Cosmetic Science, 2019
- [Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis](https://pubmed.ncbi.nlm.nih.gov/33128473/) Borago officinalis oil, Borago officinalis seed oil · Lipids, 2020
- [Development, Characterization, and Clinical Investigation of a New Topical Emulsion System Containing a Castanea sativa Spiny Burs Active Extract](https://pubmed.ncbi.nlm.nih.gov/34683927/) Chestnut leaf extract · Pharmaceutics, 2021
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Betaine · Molecules, 2024
- [Microbicidal activity of tripotassium phosphate and fatty acids toward spoilage and pathogenic bacteria associated with poultry](https://pubmed.ncbi.nlm.nih.gov/16013388/) Myristic acid · Journal of Food Protection, 2005
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 2-o-ethyl ascorbic acid · Polymers, 2023
- [Synergistic approach for acne vulgaris treatment using glycerosomes loaded with lincomycin and lauric acid: Formulation, in silico, in vitro, LC-MS/MS skin deposition assay and in vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/37805147/) Lauric acid · International Journal of Pharmaceutics, 2023
- [Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects](https://pubmed.ncbi.nlm.nih.gov/39383579/) Palmitoyl tripeptide-5 · Colloids and Surfaces. B, Biointerfaces, 2025
- [Effects of Investigational Moisturizers on the Skin Barrier and Microbiome following Exposure to Environmental Aggressors: A Randomized Clinical Trial and Ex Vivo Analysis](https://pubmed.ncbi.nlm.nih.gov/37763018/) Hydrolyzed yeast extract · Journal of Clinical Medicine, 2023
- [Epigallocatechin Gallate Enzymatic Alpha Glucosylation Potentiates Its Skin-Lightening Activity-Involvement of Skin Microbiota](https://pubmed.ncbi.nlm.nih.gov/39598779/) Camellia oleifera leaf extract camellia sinensis leaf extract · Molecules, 2024
- [Novel beads made of alpha-cyclodextrin and oil for topical delivery of a lipophilic drug](https://pubmed.ncbi.nlm.nih.gov/17671830/) Glycine soja oil soybean oil · Pharmaceutical Research, 2008
- [Randomized prospective study of low-dose isotretinoin alone and combination with salicylic acid and mandelic peel against acne tarda](https://pubmed.ncbi.nlm.nih.gov/35388606/) Mandelic acid · Journal of Cosmetic Dermatology, 2022
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid](https://pubmed.ncbi.nlm.nih.gov/38794349/) Betaine · Pharmaceutics, 2024
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Anatomical site differences of sodium lauryl sulfate-induced irritation: randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/30637727/) Sodium lauryl sulfate · The British Journal of Dermatology, 2019
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively](https://pubmed.ncbi.nlm.nih.gov/12535284/) Betaine · Skin Research and Technology, 2003
- [Skin recovery by Lavandula angustifolia leaf callus extract: Redox control of Nrf2 signaling](https://pubmed.ncbi.nlm.nih.gov/40345503/) Lavandula angustifolia oil lavender oil · Free Radical Biology & Medicine, 2025
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, Panthenol vitamin b5 · Journal of Cosmetic Dermatology, 2025
- [Standardized wild apple fruit extract as a bioactive agent in dermocosmetic products for efficacy skin hydration-In vitro and in vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/35048513/) Pyrus malus fruit extract · Journal of Cosmetic Dermatology, 2022
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [The effect of a vitamin A palmitate and antioxidant-containing oil-based moisturizer on photodamaged skin of several body sites](https://pubmed.ncbi.nlm.nih.gov/23438139/) Retinyl palmitate · Journal of Cosmetic Dermatology, 2013
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Avobenzone · European Journal of Pharmaceutical Sciences, 2023
- [Prospective, randomized, double-blind clinical study of split-body comparison of topical hydroquinone and hexylresorcinol for skin pigment appearance](https://pubmed.ncbi.nlm.nih.gov/36502500/) Hexylresorcinol · Archives of Dermatological Research, 2023
- [Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/27430380/) Diglycerin · Journal of Oleo Science, 2016
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Combining Topical and Oral Botanicals for Skin Redness, Pigmentation, Sleep, and Mood: A Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/36431167/) Theanine · Journal of Clinical Medicine, 2022
- [Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes](https://pubmed.ncbi.nlm.nih.gov/39778604/) 2-o-ethyl ascorbic acid · Free Radical Biology & Medicine, 2025
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Improving the outcome of treating striae gravidarum by combined therapies using topical β-glucan and 1565-nm non-ablative fractional laser: A prospective randomized vehicle-controlled parallel group study](https://pubmed.ncbi.nlm.nih.gov/35570397/) Beta-glucan · The Journal of Dermatology, 2022
- [Treatment of Stretch Marks Using a New Formulation Combining Nanofractional Radiofrequency Plus Magnetic Nanofractional Radiofrequency](https://pubmed.ncbi.nlm.nih.gov/37171578/) Beta-glucan · Dermatology and Therapy, 2023
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Transdermal Delivery of Baicalin Based on Bio-Vesicles and Its Efficacy in Antiaging of the Skin](https://pubmed.ncbi.nlm.nih.gov/39946269/) Scutellaria baicalensis root extract · Journal of Cosmetic Dermatology, 2025
- [Effect of isosecotanapartholide isolated from Artemisia princeps Pampanini on IL‑33 production and STAT‑1 activation in HaCaT keratinocytes](https://pubmed.ncbi.nlm.nih.gov/28447741/) Artemisia princeps leaf extract · Molecular Medicine Reports, 2017
- [Liposomal formulation of a vitamin C derivative: a promising strategy to increase skin permeability](https://pubmed.ncbi.nlm.nih.gov/39985147/) 2-o-ethyl ascorbic acid · Journal of Liposome Research, 2025
- [Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients](https://pubmed.ncbi.nlm.nih.gov/41628877/) 2-o-ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026
- [Noninvasive Monitoring of Palmitoyl Hexapeptide-12 in Human Skin Layers: Mechanical Interaction with Skin Components and Its Potential Skincare Benefits](https://pubmed.ncbi.nlm.nih.gov/39964201/) Palmitoyl hexapeptide-12 · ACS Applied Bio Materials, 2025
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl methoxycinnamate, Octocrylene · Archives of Dermatological Research, 2024
- [Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling](https://pubmed.ncbi.nlm.nih.gov/35920724/) Portulaca oleracea extract purslane extract · Cutaneous and Ocular Toxicology, 2022
- [Topical application of retinyl propionate, 4 hexyl resorcinol, and niacinamide reverses molecular and clinical features of ageing](https://pubmed.ncbi.nlm.nih.gov/38685700/) Retinyl propionate · International Journal of Cosmetic Science, 2024
- [Retinyl propionate and climbazole combination demonstrates clinical improvement to the appearance of hyperpigmentation and deep wrinkling with minimal irritation](https://pubmed.ncbi.nlm.nih.gov/28733999/) Retinyl propionate · International Journal of Cosmetic Science, 2017
- [Potassium 4-Methoxysalicylate (4MSK) Exerts a Skin Lightening Effect by Acting on Melanocytes and Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/40071590/) Potassium methoxysalicylate · Journal of Cosmetic Dermatology, 2025
- [New Chalcone-Derived Molecule for the Topical Regulation of Hyperpigmentation and Skin Aging](https://pubmed.ncbi.nlm.nih.gov/39598529/) Angelica keiskei leaf extract · Pharmaceutics, 2024
- [Mitigation of ultraviolet-induced erythema and inflammation by para-hydroxycinnamic acid in human skin](https://pubmed.ncbi.nlm.nih.gov/39138602/) Ethylhexyl methoxycinnamate · International Journal of Cosmetic Science, 2025
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter, Saccharide isomerate · Lasers in Medical Science, 2025
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [Low-temperature extracted Portulaca oleracea L. as a functional ingredient in facial masks for photorejuvenation of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41182319/) Portulaca oleracea extract purslane extract · Cutaneous and Ocular Toxicology, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study](https://pubmed.ncbi.nlm.nih.gov/41211697/) Saccharide isomerate · The Journal of Dermatological Treatment, 2025
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tetrapeptide-7, Palmitoyl tripeptide-1 · International Journal of Cosmetic Science, 2026
- [Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/37194909/) Uji green tea extract · Journal of Cosmetic Dermatology, 2023
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Homosalate · Journal of Drugs in Dermatology, 2025

## The brands

- American skincare: [Paula's Choice](https://lovi.care/skincare/nl/brands/paula-s-choice)
- Japanese skincare: [Shiseido](https://lovi.care/skincare/nl/brands/shiseido)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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- United Arab Emirates: https://lovi.care/skincare/ae/compare/paula-s-choice-vs-shiseido