# Mesoestetic vs Blume Page: https://lovi.care/skincare/nl/compare/mesoestetic-vs-blume The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands. Mesoestetic and Blume are distinct skincare brands founded in Spain and Canada respectively, offering targeted [serums](https://lovi.care/skincare/nl/ingredients/serum), nourishing moisturizers, and meticulously crafted formulas that elevate daily routines. Mesoestetic suits mature, sensitive, and uneven skin best, with standout solutions like the Cosmelan 2 for acne-prone skin, while the Canadian brand suits sensitive, acne-prone, and dry skin best, featuring standout products like the Meltdown Gel Cream. Both brands differ in their founding eras and specialized ingredients, yet every application from each delivers balanced nourishment to support long-term skin health and a healthy complexion. Mesoestetic is a Spanish skincare brand founded in 1984 and owned by Mesoestetic Pharma Group, S.L.. [mesoestetic.com](https://www.mesoestetic.com/about-us) [tracxn.com](https://tracxn.com/d/companies/mesoestetic/__1eAnF7uALQzHII_So8HqZbHfSUJuilusj9hTisrG0tk) Blume is a Canadian skincare brand founded in 2018. [beautymatter.com](https://beautymatter.com/articles/next50-2025-blume) [businessinsider.com](https://www.businessinsider.com/millennial-cofounders-feminine-care-startup-blume-raised-millions-one-month) [tracxn.com](https://tracxn.com/d/companies/blume/__jaX9OkWmricZDTbbibw7yJbRPVQYVtNZDJ0cH8e2j4s) [blume.com](https://www.blume.com/blogs/blume-university/blume-formerly-known-as-ellebox) This page compares some of the most popular Mesoestetic and Blume products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg6c84da5a3d). ### Popular Mesoestetic vs Blume products #### Blume - [Meltdown Gel Cream](https://lovi.care/skincare/nl/p/blume/meltdown-gel-cream/for/acne-prone-skin) — High fit #### Mesoestetic - [Cosmelan 2](https://lovi.care/skincare/nl/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit ## Questions and answers ### Mesoestetic or Blume: which is better? Blume fits acne-prone, oily, and sensitive skin at a High level on Lovi, while Mesoestetic fits those skin types at Average or Low levels. Both brands offer products with no fragrance. ### What is the difference between Mesoestetic and Blume? Blume has a High Lovi fit for acne-prone skin with its Meltdown Gel Cream, whereas Mesoestetic has an Average fit with Cosmelan 2. Both brands feature no fragrance across all products on this page. ### Which is more affordable, Mesoestetic or Blume? I cannot answer that question because the provided page facts do not include pricing or affordability details for either Mesoestetic or Blume. ### Which causes fewer breakouts, Mesoestetic or Blume? Blume is a better fit for acne-prone skin, as Lovi rates Meltdown Gel Cream as having a High fit for acne-prone and oily acne-prone skin, whereas Mesoestetic rates an Average fit for those skin types. ### Where were Mesoestetic and Blume founded, and in what years? Mesoestetic was founded in 1984 in Spain, while Blume was founded in 2018 in Canada. ### How do Mesoestetic and Blume differ in terms of company ownership? Mesoestetic is owned by Mesoestetic Pharma Group, S.L. and was founded in Spain, whereas Blume is independently owned and was founded in Canada. ### Do products from Mesoestetic and Blume contain fragrance according to their ingredients? No, every product from Mesoestetic and Blume on this page lists no fragrance in its ingredients. ## Research behind their key ingredients - [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002 - [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022 - [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Centella asiatica extract · Indian Journal of Pharmaceutical Sciences, 2016 - [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018 - [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramides · Scientific Reports, 2022 - [Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study](https://pubmed.ncbi.nlm.nih.gov/34211271/) Retinyl palmitate · International Journal of Nanomedicine, 2021 - [Licochalcone A activates Nrf2 in vitro and contributes to licorice extract-induced lowered cutaneous oxidative stress in vivo](https://pubmed.ncbi.nlm.nih.gov/25381913/) Licorice root extract · Experimental Dermatology, 2015 - [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021 - [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017 - [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021 - [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020 - [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica extract · Molecules, 2023 - [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024 - [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024 - [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023 - [Standardized Terminalia chebula Fruit Extract: A Natural Ingredient That Provides Long-Lasting Antioxidant Protection and Reverses Visible Signs of Pollution-Induced Skin Damage](https://pubmed.ncbi.nlm.nih.gov/34557011/) Terminalia chebula fruit extract · Clinical, Cosmetic and Investigational Dermatology, 2021 - [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Terminalia chebula fruit extract · Health Science Reports, 2025 ## The brands - Spanish skincare: [Mesoestetic](https://lovi.care/skincare/nl/brands/mesoestetic) - Canadian skincare: [Blume](https://lovi.care/skincare/nl/brands/blume) ## More comparisons - [SKIN1004 vs Mesoestetic](https://lovi.care/skincare/nl/compare/skin1004-vs-mesoestetic) - [SKIN1004 vs Blume](https://lovi.care/skincare/nl/compare/skin1004-vs-blume) - [Anua vs Mesoestetic](https://lovi.care/skincare/nl/compare/anua-vs-mesoestetic) - [Anua vs Blume](https://lovi.care/skincare/nl/compare/anua-vs-blume) - [Medicube vs Mesoestetic](https://lovi.care/skincare/nl/compare/medicube-vs-mesoestetic) - [Medicube vs Blume](https://lovi.care/skincare/nl/compare/medicube-vs-blume) - [The Ordinary vs Mesoestetic](https://lovi.care/skincare/nl/compare/the-ordinary-vs-mesoestetic) - [The Ordinary vs Blume](https://lovi.care/skincare/nl/compare/the-ordinary-vs-blume) - [Beauty of Joseon vs Mesoestetic](https://lovi.care/skincare/nl/compare/beauty-of-joseon-vs-mesoestetic) - [Beauty of Joseon vs Blume](https://lovi.care/skincare/nl/compare/beauty-of-joseon-vs-blume) - [COSRX vs Mesoestetic](https://lovi.care/skincare/nl/compare/cosrx-vs-mesoestetic) - [COSRX vs Blume](https://lovi.care/skincare/nl/compare/cosrx-vs-blume) - [CeraVe vs Mesoestetic](https://lovi.care/skincare/nl/compare/cerave-vs-mesoestetic) - [CeraVe vs Blume](https://lovi.care/skincare/nl/compare/cerave-vs-blume) - [La Roche-Posay vs Mesoestetic](https://lovi.care/skincare/nl/compare/la-roche-posay-vs-mesoestetic) - [La Roche-Posay vs Blume](https://lovi.care/skincare/nl/compare/la-roche-posay-vs-blume) - [Dr. Althea vs Mesoestetic](https://lovi.care/skincare/nl/compare/dr-althea-vs-mesoestetic) - [Dr. Althea vs Blume](https://lovi.care/skincare/nl/compare/dr-althea-vs-blume) - [Some By Mi vs Mesoestetic](https://lovi.care/skincare/nl/compare/some-by-mi-vs-mesoestetic) - [Some By Mi vs Blume](https://lovi.care/skincare/nl/compare/some-by-mi-vs-blume) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/compare/mesoestetic-vs-blume - United Kingdom: https://lovi.care/skincare/uk/compare/mesoestetic-vs-blume - Ireland: https://lovi.care/skincare/ie/compare/mesoestetic-vs-blume - Germany: https://lovi.care/skincare/de/compare/mesoestetic-vs-blume - France: https://lovi.care/skincare/fr/compare/mesoestetic-vs-blume - Italy: https://lovi.care/skincare/it/compare/mesoestetic-vs-blume - Netherlands: https://lovi.care/skincare/nl/compare/mesoestetic-vs-blume (this page) - Spain: https://lovi.care/skincare/es/compare/mesoestetic-vs-blume - Canada: https://lovi.care/skincare/ca/compare/mesoestetic-vs-blume - Australia: https://lovi.care/skincare/au/compare/mesoestetic-vs-blume - Singapore: https://lovi.care/skincare/sg/compare/mesoestetic-vs-blume - Saudi Arabia: https://lovi.care/skincare/sa/compare/mesoestetic-vs-blume - United Arab Emirates: https://lovi.care/skincare/ae/compare/mesoestetic-vs-blume