# Medik8 vs Simple

Page: https://lovi.care/skincare/nl/compare/medik8-vs-simple

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Medik8 and Simple are British skincare brands representing distinct approaches to daily care, with the former founded in 2009 and the latter established in 1960. Medik8 offers [serums](https://lovi.care/skincare/nl/ingredients/serum), moisturizers, eye products, and toners built around [hyaluronic acid](https://lovi.care/skincare/nl/ingredients/hyaluronic-acid), suiting dry and dry sensitive skin best while utilizing its key ingredient to lengthen toxin wrinkle effect duration. Conversely, the second brand is beloved for gentle moisturizers, makeup removers, cleansers, and toners crafted with [niacinamide](https://lovi.care/skincare/nl/ingredients/niacinamide) and [glycerin](https://lovi.care/skincare/nl/ingredients/glycerin), which suit acne-prone skin and skin with dark spots best by improving hydration, barrier function, hyperpigmentation, and aging signs. Ultimately, both differ through their targeted formulations and ideal skin types, offering specific standout choices for distinct dermatological concerns.

Medik8 is a British skincare brand founded in 2009 and owned by L'Oréal Groupe since 2025.

[loreal.com](https://www.loreal.com/en/press-release/group/l-oreal-groupe-to-acquire-a-majority-stake-in-medik8/) [medik8.com](https://www.medik8.com/pages/founders-story) [tracxn.com](https://tracxn.com/d/companies/medik8/__vqs3N9eL3EfvIq0IoeUPADts7CrlGbzm7kjy9M9QY8o)

Simple is a British skincare brand founded in 1960 and owned by Unilever PLC since 2011.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Simple_Skincare) [sec.gov](https://www.sec.gov/Archives/edgar/data/1368457/000119312511134453/dex991.htm) [prnewswire.com](https://www.prnewswire.com/news-releases/alberto-culver-announces-that-unilever-has-received-approval-from-the-us-department-of-justice-to-complete-the-acquisition-of-the-company-121400884.html) [simple.co.uk](https://www.simple.co.uk/philosophy.html)

This page compares some of the most popular Medik8 and Simple products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg422947e36e).

### Popular Medik8 vs Simple products

#### Medik8

- [Liquid Peptides](https://lovi.care/skincare/nl/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [€98.05 at Amazon](https://www.amazon.nl/dp/B0DSJNWVV6?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [CRYSTAL RETINAL 3](https://lovi.care/skincare/nl/p/medik8/crystal-retinal-3/for/mature-skin) — High fit — [€88.77 at Amazon](https://www.amazon.nl/dp/B07Y5P314G?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [C-Tetra Serum](https://lovi.care/skincare/nl/p/medik8/c-tetra-serum/for/dry-sensitive-skin) — Average fit — [€89.00 at Amazon](https://www.amazon.nl/dp/B0F6Z3V4RJ?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Bakuchiol Peptides](https://lovi.care/skincare/nl/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [€71.00 at Amazon](https://www.amazon.nl/dp/B0DP31336Z?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Crystal Retinal Ceramide Eye 3](https://lovi.care/skincare/nl/p/medik8/crystal-retinal-ceramide-eye-3/for/mature-skin) — High fit — [€53.00 at Lookfantastic](https://www.lookfantastic.nl/p/medik8-crystal-retinal-ceramide-eye-3-15ml/14271143/)
- [Oxy-R Peptides](https://lovi.care/skincare/nl/p/medik8/oxy-r-peptides/for/mature-skin) — Superior fit — [€75.25 at Amazon](https://www.amazon.nl/dp/B093R4NDJS?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Total Moisture Daily Facial Cream](https://lovi.care/skincare/nl/p/medik8/total-moisture-daily-facial-cream/for/mature-skin) — High fit — [€65.00 at Notino](https://www.notino.nl/medik8/total-moisture-gezichtscreme-met-hydraterende-werking/p-16269775/)
- [Hydr8 B5 Intense](https://lovi.care/skincare/nl/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [€64.50 at Notino](https://www.notino.nl/medik8/hydro8-b5-intense-hyaluronzuur-serum/p-16088887/)

#### Simple

- [Micellar Water](https://lovi.care/skincare/nl/p/simple/micellar-water/for/mature-skin) — Average fit — [€12.27 at Amazon](https://www.amazon.nl/dp/B00X3OQ6N0?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Micellar Cleansing Water](https://lovi.care/skincare/nl/p/simple/micellar-cleansing-water/for/sensitive-skin) — High fit — [€12.27 at Amazon](https://www.amazon.nl/dp/B00X3OQ6N0?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Hydrating Light Moisturiser](https://lovi.care/skincare/nl/p/simple/hydrating-light-moisturiser/for/dry-skin) — Average fit — [€15.31 at Amazon](https://www.amazon.nl/dp/B000LQX6XG?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Refreshing Facial Wash](https://lovi.care/skincare/nl/p/simple/refreshing-facial-wash/for/acne-prone-skin) — Average fit — [€11.17 at Amazon](https://www.amazon.nl/dp/B000LQUA6M?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Replenishing Rich Moisturiser](https://lovi.care/skincare/nl/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [€15.31 at Amazon](https://www.amazon.nl/dp/B000LQX6XG?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Water Boost Hydrating Gel Cream](https://lovi.care/skincare/nl/p/simple/water-boost-hydrating-gel-cream/for/dry-skin) — Average fit — [€15.31 at Amazon](https://www.amazon.nl/dp/B000LQX6XG?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Kind to Skin Soothing Facial Toner](https://lovi.care/skincare/nl/p/simple/kind-to-skin-soothing-facial-toner/for/mature-skin) — Superior fit — [€7.44 at Amazon](https://www.amazon.nl/dp/B014G4Z42O?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)

## People Say

Medik8

Simple

- Gentle and non-irritating formulation Mostly Mentioned Mostly Mentioned “Does not cause any form of irritation on the skin which I love. — Simple Micellar Cleansing Water” “The only cleanser that doesn't turn my face red. — Simple Micellar Water” “no artificial perfume — Simple Hydrating Light Moisturiser” “zero irritation or peeling — Medik8 CRYSTAL RETINAL 3”
- Hydrating texture and formula Rarely Noted Mostly Mentioned “banished dryness within days — Simple Replenishing Rich Moisturiser” “Instantly boosts skin's hydration... face doesn't feel dry and tight. — Simple Micellar Cleansing Water” “Leaves my face feeling soft, not tight. — Simple Micellar Water” “sinks in beautifully — Medik8 C-Tetra Serum”
- Lightweight and elegant texture Often Mentioned Often Mentioned “absorbed effortlessly — Medik8 Total Moisture Daily Facial Cream” “Absorbs fast — Medik8 Liquid Peptides” “sinks in instantly — Simple Water Boost Hydrating Gel Cream” “absorbs very quickly — Simple Hydrating Light Moisturiser”
- Improves skin texture and smoothness Often Mentioned Not noted “smoother skin — Medik8 Surface Radiance Cleanse” “My skin was smoother, my skin texture felt more resurfaced. — Medik8 Sleep Glycolic” “skin feels baby soft — Medik8 CRYSTAL RETINAL 3”
- Value for money and affordability Rarely Noted Often Mentioned “great value for money — Simple Kind to Skin Soothing Facial Toner” “super affordable — Simple Hydrating Light Moisturiser” “Can't beat the price for the quality. — Simple Micellar Water” “better value than Skinceuticals — Medik8 Super C Ferulic”
- Fades dark spots and brightens Often Mentioned Not noted “I wake up glowing. It adds back that youthful bloom that I've lost. — Medik8 Sleep Glycolic” “pigmentation lightened slightly — Medik8 Oxy-R Peptides” “immediate glow — Medik8 Super C Ferulic”
- High price point Often Mentioned Not noted “Expensive per bottle — Medik8 Liquid Peptides”
- Caused breakouts Rarely Noted Sometimes Noted “made me break out constantly — Medik8 C-Tetra Serum” “caused breakouts — Medik8 Oxy-R Peptides” “caused me to breakout — Medik8 Total Moisture Daily Facial Cream” “Gave me tiny bumps on my forehead. — Simple Micellar Water”
- Packaging issues and fragility Sometimes Noted Rarely Noted “Worried about the snap top bottle leaking when travelling. — Simple Micellar Cleansing Water” “The cap broke off immediately. — Simple Micellar Water” “hard to get last bit out — Simple Replenishing Rich Moisturiser” “Glass bottle breaks easily — Medik8 Liquid Peptides”

### Medik8 vs Simple routines for dry skin

#### Medik8-focused routine

- Cleanser: [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [€21.95 at Amazon](https://www.amazon.nl/dp/B01N7T7JKJ?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/nl/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — [€16.89 at Amazon](https://www.amazon.nl/dp/B07B65NJLV?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/nl/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [€64.50 at Notino](https://www.notino.nl/medik8/hydro8-b5-intense-hyaluronzuur-serum/p-16088887/) — Morning · Evening · Once a week
- SPF: [Purito Daily Soft Touch Sunscreen](https://lovi.care/skincare/nl/p/purito/daily-soft-touch-sunscreen/for/dry-skin) — Superior fit — [€20.01 at Amazon](https://www.amazon.nl/dp/B0BS21D6SW?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/nl/p/medik8/press-and-glow/for/dry-skin) — Superior fit — [€41.99 at Amazon](https://www.amazon.nl/dp/B08KYV8H21?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Bakuchiol Peptides](https://lovi.care/skincare/nl/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [€71.00 at Amazon](https://www.amazon.nl/dp/B0DP31336Z?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [LANEIGE Water Sleeping Mask_EX](https://lovi.care/skincare/nl/p/laneige/water-sleeping-mask-ex/for/dry-skin) — Superior fit — [€33.90 at Amazon](https://www.amazon.nl/dp/B07XFLXW3S?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/nl/p/simple/refreshing-facial-wash/for/dry-skin) — Low fit — [€11.17 at Amazon](https://www.amazon.nl/dp/B000LQUA6M?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/nl/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — [€16.89 at Amazon](https://www.amazon.nl/dp/B07B65NJLV?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/nl/p/simple/replenishing-rich-moisturiser/for/dry-skin) — Average fit — [€15.31 at Amazon](https://www.amazon.nl/dp/B000LQX6XG?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Purito Daily Soft Touch Sunscreen](https://lovi.care/skincare/nl/p/purito/daily-soft-touch-sunscreen/for/dry-skin) — Superior fit — [€20.01 at Amazon](https://www.amazon.nl/dp/B0BS21D6SW?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/nl/p/simple/micellar-cleansing-water/for/dry-skin) — High fit — [€12.27 at Amazon](https://www.amazon.nl/dp/B00X3OQ6N0?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [ROUND LAB 1025 Dokdo Cleansing Water](https://lovi.care/skincare/nl/p/round-lab/1025-dokdo-cleansing-water/for/dry-skin) — Superior fit — [€13.99 at Amazon](https://www.amazon.nl/dp/B0BPB4KMJP?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/nl/p/peach-and-lily/glass-skin-refining-serum/for/dry-skin) — Superior fit — [€86.59 at Amazon](https://www.amazon.nl/dp/B08H4QPM19?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [LANEIGE Water Sleeping Mask_EX](https://lovi.care/skincare/nl/p/laneige/water-sleeping-mask-ex/for/dry-skin) — Superior fit — [€33.90 at Amazon](https://www.amazon.nl/dp/B07XFLXW3S?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 98% fit](https://lovi.care/skincare/nl/skin/dry-skin)

### Medik8 vs Simple routines for oily skin

#### Medik8-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/nl/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [€21.00 at Amazon](https://www.amazon.nl/dp/B01N1LL62W?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [€19.90 at Amazon](https://www.amazon.nl/dp/B08125WDCF?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/nl/p/medik8/hydr8-b5-intense/for/oily-skin) — High fit — [€64.50 at Notino](https://www.notino.nl/medik8/hydro8-b5-intense-hyaluronzuur-serum/p-16088887/) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — [€33.70 at Amazon](https://www.amazon.nl/dp/B0CF22FB86?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/oily-skin) — High fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/nl/p/medik8/press-and-glow/for/oily-skin) — Average fit — [€41.99 at Amazon](https://www.amazon.nl/dp/B08KYV8H21?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Oxy-R Peptides](https://lovi.care/skincare/nl/p/medik8/oxy-r-peptides/for/oily-skin) — High fit — [€75.25 at Amazon](https://www.amazon.nl/dp/B093R4NDJS?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/nl/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€72.82 at Amazon](https://www.amazon.nl/dp/B0D1YJN279?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/nl/p/vt-cosmetics/cica-purifying-mask/for/oily-skin) — High fit — [€15.72 at Amazon](https://www.amazon.nl/dp/B083X5R6VR?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/nl/p/simple/refreshing-facial-wash/for/oily-skin) — Average fit — [€11.17 at Amazon](https://www.amazon.nl/dp/B000LQUA6M?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [€19.90 at Amazon](https://www.amazon.nl/dp/B08125WDCF?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/nl/p/simple/replenishing-rich-moisturiser/for/oily-skin) — Average fit — [€15.31 at Amazon](https://www.amazon.nl/dp/B000LQX6XG?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — [€33.70 at Amazon](https://www.amazon.nl/dp/B0CF22FB86?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/nl/p/simple/micellar-cleansing-water/for/oily-skin) — High fit — [€12.27 at Amazon](https://www.amazon.nl/dp/B00X3OQ6N0?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/nl/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [€18.05 at Amazon](https://www.amazon.nl/dp/B09SN5B88W?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [The Ordinary Niacinamide 10% + Zinc 1%](https://lovi.care/skincare/nl/p/the-ordinary/niacinamide-10-zinc-1/for/oily-skin) — Superior fit — [€5.75 at Amazon](https://www.amazon.nl/dp/B01MDTVZTZ?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/nl/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€72.82 at Amazon](https://www.amazon.nl/dp/B0D1YJN279?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/nl/p/vt-cosmetics/cica-purifying-mask/for/oily-skin) — High fit — [€15.72 at Amazon](https://www.amazon.nl/dp/B083X5R6VR?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 95% fit](https://lovi.care/skincare/nl/skin/oily-skin)

### Medik8 vs Simple routines for combination skin

#### Medik8-focused routine

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/nl/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — [€16.50 at Amazon](https://www.amazon.nl/dp/B07RY6Q6QM?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [€36.00 at Amazon](https://www.amazon.nl/dp/B07P7VZ2J9?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/nl/p/medik8/hydr8-b5-intense/for/combination-skin) — High fit — [€64.50 at Notino](https://www.notino.nl/medik8/hydro8-b5-intense-hyaluronzuur-serum/p-16088887/) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — [€33.70 at Amazon](https://www.amazon.nl/dp/B0CF22FB86?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/combination-skin) — Superior fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/nl/p/medik8/press-and-glow/for/combination-skin) — High fit — [€41.99 at Amazon](https://www.amazon.nl/dp/B08KYV8H21?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Oxy-R Peptides](https://lovi.care/skincare/nl/p/medik8/oxy-r-peptides/for/combination-skin) — High fit — [€75.25 at Amazon](https://www.amazon.nl/dp/B093R4NDJS?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/nl/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — [€15.72 at Amazon](https://www.amazon.nl/dp/B083X5R6VR?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

#### Simple-focused routine

- Cleanser: [Refreshing Facial Wash](https://lovi.care/skincare/nl/p/simple/refreshing-facial-wash/for/combination-skin) — Average fit — [€11.17 at Amazon](https://www.amazon.nl/dp/B000LQUA6M?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [€36.00 at Amazon](https://www.amazon.nl/dp/B07P7VZ2J9?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Replenishing Rich Moisturiser](https://lovi.care/skincare/nl/p/simple/replenishing-rich-moisturiser/for/combination-skin) — Average fit — [€15.31 at Amazon](https://www.amazon.nl/dp/B000LQX6XG?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — [€33.70 at Amazon](https://www.amazon.nl/dp/B0CF22FB86?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Micellar Cleansing Water](https://lovi.care/skincare/nl/p/simple/micellar-cleansing-water/for/combination-skin) — Average fit — [€12.27 at Amazon](https://www.amazon.nl/dp/B00X3OQ6N0?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/nl/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [€16.99 at Amazon](https://www.amazon.nl/dp/B09V7Z4TJG?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/nl/p/peach-and-lily/glass-skin-refining-serum/for/combination-skin) — Superior fit — [€86.59 at Amazon](https://www.amazon.nl/dp/B08H4QPM19?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/nl/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — [€15.72 at Amazon](https://www.amazon.nl/dp/B083X5R6VR?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 94% fit](https://lovi.care/skincare/nl/skin/combination-skin)

## Questions and answers

### Medik8 or Simple: which is better?

Medik8 is better for dry, dry sensitive, and sensitive skin, where Lovi rates its routines as Superior. Simple offers better value for money and gentler, more hydrating formulations according to reviewers, but Medik8 performs better for improving skin texture and fading dark spots.

### What is the difference between Medik8 and Simple?

Medik8 is best for dry, dry sensitive, and sensitive skin with a Superior routine fit, while Simple focuses best on acne-prone skin, skin with dark spots, and oily skin. The products on this page from Medik8 feature key ingredients like [hyaluronic acid](https://lovi.care/skincare/nl/ingredients/hyaluronic-acid) to help improve hydration, whereas Simple uses ingredients like [niacinamide](https://lovi.care/skincare/nl/ingredients/niacinamide) to help manage pigmentation.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Medik8 or Simple for dry skin?

Medik8 is the better choice for dry skin, as the products on this page achieve a Superior routine fit compared to Simple's High fit. The key ingredient hyaluronic acid helps deliver deep hydration and anti-aging benefits.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Medik8 or Simple: which cleanser is better?

Medik8 Surface Radiance Cleanse has a superior Lovi fit for acne-prone skin and skin with dark spots on the products on this page, whereas Simple Refreshing Facial Wash has an average fit for those skin types.

### Which is more affordable, Medik8 or Simple?

Simple is more affordable, as its products offer value for money and lower price points compared to Medik8, which reviewers often note has a high price point.

### Between Medik8 and Simple, which brand is better for dry sensitive skin?

Medik8 is better for dry sensitive skin, achieving a Superior routine fit compared to Simple's High fit on the products on this page. The key ingredients across the products on this page help provide deep hydration and skin quality improvements.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### Which brand has fragrance-free products, Medik8 or Simple?

Both Medik8 and Simple offer products on this page that list no fragrance in their ingredients. Simple features fragrance-free formulas across all its products, while 11 of the 12 Medik8 products on this page are also fragrance-free.

### What are the main company background differences between Medik8 and Simple?

Medik8 was founded in 2009 in the United Kingdom and is owned by L'Oréal Groupe, while Simple was founded in 1960 in the United Kingdom and is owned by Unilever PLC.

### Medik8 or Simple for oily skin?

Medik8 and Simple both offer high routine fit levels for oily skin on the products on this page. Reviewers report that Simple provides lightweight, value-friendly moisturizers, while Medik8 features key ingredients like hyaluronic acid to help deliver hydration.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Medik8 or Simple: which moisturizer is better?

Medik8 is generally better for intense or targeted moisture, with products on this page like Hydr8 B5 Intense achieving a Superior fit for dry skin. Simple focuses more on everyday lightweight hydration, such as with its Hydrating Light Moisturiser, which may work well for basic daily use.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Medik8 or Simple for sensitive skin?

Medik8 is the better fit for sensitive skin, earning a Superior routine fit level compared to Simple's High. The products on this page for Medik8 feature gentle and non-irritating formulations and key ingredients like hyaluronic acid that helps improve skin quality.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Medik8 or Simple for acne-prone skin?

Medik8 and Simple are both a High fit for acne-prone skin. Medik8 features key ingredients like hyaluronic acid to help with hydration, while Simple uses niacinamide and [glycerin](https://lovi.care/skincare/nl/ingredients/glycerin).

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, Panthenol vitamin b5 · American Journal of Clinical Dermatology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol vitamin e, Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent](https://pubmed.ncbi.nlm.nih.gov/25648593/) Hydrolyzed opuntia ficus-indica flower extract · Molecules, 2015
- [Topical anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica](https://pubmed.ncbi.nlm.nih.gov/25821823/) Hydrolyzed opuntia ficus-indica flower extract · BioMed Research International, 2015
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [Topical delivery of tetrahydrocurcumin lipid nanoparticles effectively inhibits skin inflammation: in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/29938544/) Tetrahydrodiferuloylmethane · Drug Development and Industrial Pharmacy, 2018
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012
- [Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/26061570/) Hydrolyzed opuntia ficus-indica flower extract · Journal of Medicinal Food, 2015
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol vitamin e, Ferulic acid · Journal of Cosmetic Dermatology, 2020
- [Inhibitory effect of mulberroside A and its derivatives on melanogenesis induced by ultraviolet B irradiation](https://pubmed.ncbi.nlm.nih.gov/21946069/) Hydroxyresveratrol · Food and Chemical Toxicology, 2011
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, Panthenol vitamin b5 · The Journal of Dermatological Treatment, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Urologia Internationalis, 2019
- [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Moisturizing factors nmf, Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone, Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Panthenol, Panthenol vitamin b5, Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel leaf water · Phytochemistry, 2001
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Moisturizing factors nmf · Molecules, 2021
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Efficacy and Tolerability of Topical Nicotinamide Plus Antibacterial Adhesive Agents and Zinc-Pyrrolidone Carboxylic Acid Versus Placebo as an Adjuvant Treatment for Moderate Acne Vulgaris in Indonesia: A Multicenter, Double-blind, Randomized, Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32983333/) Zinc pca · The Journal of Clinical and Aesthetic Dermatology, 2020
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Understanding Solar Skin Elastosis-Cause and Treatment](https://pubmed.ncbi.nlm.nih.gov/30052192/) Witch hazel leaf water · Journal of Cosmetic Science, 2018
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Aloe barbadensis flower extract · Molecules, 2024
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial](https://pubmed.ncbi.nlm.nih.gov/40464749/) Ferulic acid · The Journal of Dermatological Treatment, 2025
- [Borage Oil Treated with Immobilized Lipase Inhibits Melanogenesis](https://pubmed.ncbi.nlm.nih.gov/33128473/) Borago officinalis seed oil · Lipids, 2020
- [Depth-dependent hydration dynamics in human skin: Vehicle-controlled efficacy assessment of a functional 10% urea plus NMF moisturizer by near-infrared confocal spectroscopic imaging (KOSIM IR) and capacitance method complemented by volunteer perception](https://pubmed.ncbi.nlm.nih.gov/35034387/) Moisturizing factors nmf · Skin Research and Technology, 2022
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/35745923/) Moringa oleifera seed oil · Polymers, 2022
- [Assessment of the efficacy and safety of a new complex skin cream in Asian women: A controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/28512843/) Hydroxyresveratrol · Journal of Cosmetic Dermatology, 2017
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, Panthenol vitamin b5 · Journal of Cosmetic Dermatology, 2025
- [Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects](https://pubmed.ncbi.nlm.nih.gov/22142309/) Sodium ascorbyl phosphate · Experimental Dermatology, 2012
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/) Pha polyhydroxy acid · Cutis, 2004
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Saccharide isomerate · Lasers in Medical Science, 2025
- [Preclinical Safety Evaluation of Dual Drug-Loaded Nanolipidic Carriers of Dissolvable Patches: In-Vitro and In-Vivo Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/41186117/) Tetrahydrodiferuloylmethane · Molecular Pharmaceutics, 2025
- [Acai Oil-Based Organogel Containing Hyaluronic Acid for Topical Cosmetic: In Vitro and Ex Vivo Assessment](https://pubmed.ncbi.nlm.nih.gov/39339231/) Euterpe oleracea fruit extract · Pharmaceutics, 2024
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [A novel facial moisturizer containing Saccharide isomerate accelerates skin barrier restoration following intense pulsed light treatment: a randomized split-face study](https://pubmed.ncbi.nlm.nih.gov/41211697/) Saccharide isomerate · The Journal of Dermatological Treatment, 2025
- [Saccharide isomerate ameliorates cosmetic scalp conditions in a Chinese study population](https://pubmed.ncbi.nlm.nih.gov/35279940/) Saccharide isomerate · Journal of Cosmetic Dermatology, 2023

## The brands

- British skincare: [Medik8](https://lovi.care/skincare/nl/brands/medik8)
- British skincare: [Simple](https://lovi.care/skincare/nl/brands/simple)

## More comparisons

- [SKIN1004 vs Medik8](https://lovi.care/skincare/nl/compare/skin1004-vs-medik8)
- [SKIN1004 vs Simple](https://lovi.care/skincare/nl/compare/skin1004-vs-simple)
- [Anua vs Medik8](https://lovi.care/skincare/nl/compare/anua-vs-medik8)
- [Anua vs Simple](https://lovi.care/skincare/nl/compare/anua-vs-simple)
- [Medicube vs Medik8](https://lovi.care/skincare/nl/compare/medicube-vs-medik8)
- [Medicube vs Simple](https://lovi.care/skincare/nl/compare/medicube-vs-simple)
- [The Ordinary vs Medik8](https://lovi.care/skincare/nl/compare/the-ordinary-vs-medik8)
- [The Ordinary vs Simple](https://lovi.care/skincare/nl/compare/the-ordinary-vs-simple)
- [Beauty of Joseon vs Medik8](https://lovi.care/skincare/nl/compare/beauty-of-joseon-vs-medik8)
- [Beauty of Joseon vs Simple](https://lovi.care/skincare/nl/compare/beauty-of-joseon-vs-simple)
- [COSRX vs Medik8](https://lovi.care/skincare/nl/compare/cosrx-vs-medik8)
- [COSRX vs Simple](https://lovi.care/skincare/nl/compare/cosrx-vs-simple)
- [CeraVe vs Medik8](https://lovi.care/skincare/nl/compare/cerave-vs-medik8)
- [CeraVe vs Simple](https://lovi.care/skincare/nl/compare/cerave-vs-simple)
- [La Roche-Posay vs Medik8](https://lovi.care/skincare/nl/compare/la-roche-posay-vs-medik8)
- [La Roche-Posay vs Simple](https://lovi.care/skincare/nl/compare/la-roche-posay-vs-simple)
- [Dr. Althea vs Medik8](https://lovi.care/skincare/nl/compare/dr-althea-vs-medik8)
- [Dr. Althea vs Simple](https://lovi.care/skincare/nl/compare/dr-althea-vs-simple)
- [Some By Mi vs Medik8](https://lovi.care/skincare/nl/compare/some-by-mi-vs-medik8)
- [Some By Mi vs Simple](https://lovi.care/skincare/nl/compare/some-by-mi-vs-simple)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/medik8-vs-simple
- United Kingdom: https://lovi.care/skincare/uk/compare/medik8-vs-simple
- Ireland: https://lovi.care/skincare/ie/compare/medik8-vs-simple
- Germany: https://lovi.care/skincare/de/compare/medik8-vs-simple
- France: https://lovi.care/skincare/fr/compare/medik8-vs-simple
- Italy: https://lovi.care/skincare/it/compare/medik8-vs-simple
- Netherlands: https://lovi.care/skincare/nl/compare/medik8-vs-simple (this page)
- Spain: https://lovi.care/skincare/es/compare/medik8-vs-simple
- Canada: https://lovi.care/skincare/ca/compare/medik8-vs-simple
- Australia: https://lovi.care/skincare/au/compare/medik8-vs-simple
- Singapore: https://lovi.care/skincare/sg/compare/medik8-vs-simple
- Saudi Arabia: https://lovi.care/skincare/sa/compare/medik8-vs-simple
- United Arab Emirates: https://lovi.care/skincare/ae/compare/medik8-vs-simple