# Medik8 vs Aēsop

Page: https://lovi.care/skincare/nl/compare/medik8-vs-aesop

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Medik8 and Aēsop are two distinct skincare lines known for their unique approaches to daily maintenance and targeted care. Medik8 centers its British formulas on [hyaluronic acid](https://lovi.care/skincare/nl/ingredients/hyaluronic-acid), serving dry and dry sensitive skin best through specialized [serums](https://lovi.care/skincare/nl/ingredients/serum), moisturizers, eye products, and toners. Aēsop relies on botanical and scientifically validated ingredients within its thoughtfully formulated moisturizers, cleansers, and serums to suit balanced, combination, and sensitive skin. While both offer standout solutions for acne, dark spots, and mature concerns, the former emphasizes targeted molecular science while the latter leans into gentle, harmonious plant [extracts](https://lovi.care/skincare/nl/ingredients/extract).

Medik8 is a British skincare brand founded in 2009 and owned by L'Oréal Groupe since 2025.

[loreal.com](https://www.loreal.com/en/press-release/group/l-oreal-groupe-to-acquire-a-majority-stake-in-medik8/) [medik8.com](https://www.medik8.com/pages/founders-story) [tracxn.com](https://tracxn.com/d/companies/medik8/__vqs3N9eL3EfvIq0IoeUPADts7CrlGbzm7kjy9M9QY8o)

This page compares some of the most popular Medik8 and Aēsop products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgbade9b76c1).

### Popular Medik8 vs Aēsop products

#### Medik8

- [Liquid Peptides](https://lovi.care/skincare/nl/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [€98.05 at Amazon](https://www.amazon.nl/dp/B0DSJNWVV6?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [CRYSTAL RETINAL 3](https://lovi.care/skincare/nl/p/medik8/crystal-retinal-3/for/mature-skin) — High fit — [€88.77 at Amazon](https://www.amazon.nl/dp/B07Y5P314G?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [C-Tetra Serum](https://lovi.care/skincare/nl/p/medik8/c-tetra-serum/for/dry-sensitive-skin) — Average fit — [€89.00 at Amazon](https://www.amazon.nl/dp/B0F6Z3V4RJ?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Bakuchiol Peptides](https://lovi.care/skincare/nl/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [€71.00 at Amazon](https://www.amazon.nl/dp/B0DP31336Z?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Crystal Retinal Ceramide Eye 3](https://lovi.care/skincare/nl/p/medik8/crystal-retinal-ceramide-eye-3/for/mature-skin) — High fit — [€53.00 at Lookfantastic](https://www.lookfantastic.nl/p/medik8-crystal-retinal-ceramide-eye-3-15ml/14271143/)
- [Oxy-R Peptides](https://lovi.care/skincare/nl/p/medik8/oxy-r-peptides/for/mature-skin) — Superior fit — [€75.25 at Amazon](https://www.amazon.nl/dp/B093R4NDJS?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Total Moisture Daily Facial Cream](https://lovi.care/skincare/nl/p/medik8/total-moisture-daily-facial-cream/for/mature-skin) — High fit — [€65.00 at Notino](https://www.notino.nl/medik8/total-moisture-gezichtscreme-met-hydraterende-werking/p-16269775/)
- [Hydr8 B5 Intense](https://lovi.care/skincare/nl/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [€64.50 at Notino](https://www.notino.nl/medik8/hydro8-b5-intense-hyaluronzuur-serum/p-16088887/)

#### Aēsop

- [Parsley Seed Facial Cleanser](https://lovi.care/skincare/nl/p/aesop/parsley-seed-facial-cleanser/for/acne-prone-skin) — Average fit
- [Damascan Rose Facial Treatment](https://lovi.care/skincare/nl/p/aesop/damascan-rose-facial-treatment/for/dry-skin) — High fit — [€129.00 at Amazon](https://www.amazon.nl/dp/B000IB0H0O?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [B Triple C Facial Balancing Gel](https://lovi.care/skincare/nl/p/aesop/b-triple-c-facial-balancing-gel/for/combination-skin) — High fit
- [Parsley Seed Anti-Oxidant Intense Serum](https://lovi.care/skincare/nl/p/aesop/parsley-seed-anti-oxidant-intense-serum/for/dark-spots) — High fit

## People Say

Medik8

Aēsop

- Deep hydration and plumping Often Mentioned Mostly Mentioned “woke up with baby-soft skin — Aēsop Damascan Rose Facial Treatment” “Savior of my winter-fueled dry skin. — Aēsop B Triple C Facial Balancing Gel” “delivers deep hydration that really fills your skin — Aēsop Parsley Seed Anti-Oxidant Intense Serum” “Restores moisture — Medik8 Liquid Peptides”
- Gentle and non-irritating formulation Mostly Mentioned Not noted “zero irritation or peeling — Medik8 CRYSTAL RETINAL 3” “only Vitamin C my sensitive skin can tolerate — Medik8 C-Tetra Serum” “Best retinol replacement — Medik8 Bakuchiol Peptides”
- Pleasant experience and scent Sometimes Noted Often Mentioned “smells divine — Aēsop Damascan Rose Facial Treatment” “Soft herbal scent that feels fresh and floral. — Aēsop Parsley Seed Facial Cleanser” “smells like a spa — Medik8 CRYSTAL RETINAL 3”
- Lightweight and elegant texture Often Mentioned Sometimes Noted “absorbed effortlessly — Medik8 Total Moisture Daily Facial Cream” “Absorbs fast — Medik8 Liquid Peptides” “Texture is divine — Medik8 Bakuchiol Peptides” “absorbs well into the skin — Aēsop Damascan Rose Facial Treatment”
- Improves skin texture Often Mentioned Not noted “smoother skin — Medik8 Surface Radiance Cleanse” “My skin was smoother, my skin texture felt more resurfaced. — Medik8 Sleep Glycolic” “skin feels baby soft — Medik8 CRYSTAL RETINAL 3”
- Brightening and glow Often Mentioned Not noted “I wake up glowing. It adds back that youthful bloom that I've lost. — Medik8 Sleep Glycolic” “unlocked a serious glow — Medik8 C-Tetra Serum” “immediate glow — Medik8 Super C Ferulic”
- High price point Often Mentioned Mostly Mentioned “Expensive per bottle — Medik8 Liquid Peptides” “very expensive for amount — Medik8 CRYSTAL RETINAL 3” “hefty price tag — Medik8 C-Tetra Serum” “quantity is too small — Aēsop Damascan Rose Facial Treatment”
- Slight tackiness or sticky texture Rarely Noted Often Mentioned “Can feel sticky if over-applied — Medik8 Liquid Peptides” “too oily — Medik8 Super C Ferulic” “Thick, almost honey-like, and needs a moment to melt in. — Aēsop B Triple C Facial Balancing Gel”
- Packaging issues and fragility Sometimes Noted Often Mentioned “Glass bottle breaks easily — Medik8 Liquid Peptides” “hard to get last bit — Medik8 CRYSTAL RETINAL 3” “click mechanism tricky — Medik8 Oxy-R Peptides” “The downside is the pump. — Aēsop Parsley Seed Facial Cleanser”
- Tricky application or pilling Not noted Often Mentioned “When applied directly to the face, it feels slippery and pills up. — Aēsop B Triple C Facial Balancing Gel”

## Questions and answers

### Medik8 or Aēsop: which is better?

Medik8 and Aēsop both have strong offerings, with Medik8 standing out for gentle formulations, lightweight textures, and brightening effects, while Aēsop excels in deep hydration and pleasant scents. Reviewers frequently note high prices for both brands.

### What is the difference between Medik8 and Aēsop?

Medik8 and Aēsop are both owned by L'Oréal Groupe, but Medik8 products on this page are rated best for dry and sensitive skin types while focusing on brightening and texture, whereas Aēsop stands out for deep hydration and non-greasy, balancing moisturizers. Reviewers note that Medik8 offers gentle [serums](https://lovi.care/skincare/nl/ingredients/serum) and lightweight textures, while Aēsop is praised for its luxurious and refreshing scents.

### Medik8 or Aēsop: which cleanser is better?

Medik8 Surface Radiance Cleanse has a Superior Lovi fit for acne-prone skin and skin with dark spots, while Aēsop Parsley Seed Facial Cleanser has an Average fit for those skin types.

### Which is more affordable, Medik8 or Aēsop?

Both Medik8 and Aēsop are mentioned by reviewers for having a high price point, so neither brand is notably more affordable than the other.

### Which causes fewer breakouts, Medik8 or Aēsop?

Medik8 is generally known for gentler, less irritating formulations on this page, while Aēsop reviewers mention non-greasy balancing. However, individual breakouts depend on your specific skin type and how each product's ingredients interact with it.

### Which brand has been owned by L'Oréal Groupe for a longer time, Medik8 or Aēsop?

Aēsop has been owned by L'Oréal Groupe for a longer time, as it was acquired in 2023, while Medik8 joined the group in 2025.

### How does the fragrance formulation compare between Medik8 and Aēsop products on this page?

The products on this page for Medik8 mostly list no fragrance except for the Total Moisture Daily Facial Cream, whereas every Aēsop product on this page lists no fragrance in its ingredients.

### Which brand is better for sensitive skin according to their brand-focused routines?

Medik8 fits sensitive skin best according to its brand-focused routines, while Aēsop does not specify a best-fit routine for sensitive skin. Medik8 features products on this page like Hydr8 B5 Intense that earn a High Lovi fit level for sensitive skin.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Medik8 or Aēsop: which moisturizer is better?

Medik8 moisturizers achieve a High fit for dry skin, dry sensitive skin, and mature skin on this page, while Aēsop's [Damascan Rose](https://lovi.care/skincare/nl/ingredients/rose) Facial Treatment and B Triple C Facial Balancing Gel also offer strong options for hydration.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review](https://pubmed.ncbi.nlm.nih.gov/30666070/) Aloe barbadensis leaf juice · Iranian Journal of Medical Sciences, 2019
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol vitamin e, Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent](https://pubmed.ncbi.nlm.nih.gov/25648593/) Hydrolyzed opuntia ficus-indica flower extract · Molecules, 2015
- [Topical anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica](https://pubmed.ncbi.nlm.nih.gov/25821823/) Hydrolyzed opuntia ficus-indica flower extract · BioMed Research International, 2015
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Lactate triggers KAT8-mediated LTBP1 lactylation at lysine 752 to promote skin rejuvenation by inducing collagen synthesis in fibroblasts](https://pubmed.ncbi.nlm.nih.gov/39102921/) Lactic acid · International Journal of Biological Macromolecules, 2024
- [Topical delivery of tetrahydrocurcumin lipid nanoparticles effectively inhibits skin inflammation: in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/29938544/) Tetrahydrodiferuloylmethane · Drug Development and Industrial Pharmacy, 2018
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Effect of Camellia japonica oil on human type I procollagen production and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/17386986/) Camellia japonica seed oil · Journal of Ethnopharmacology, 2007
- [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012
- [Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/26061570/) Hydrolyzed opuntia ficus-indica flower extract · Journal of Medicinal Food, 2015
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol vitamin e, Ferulic acid · Journal of Cosmetic Dermatology, 2020
- [Inhibitory effect of mulberroside A and its derivatives on melanogenesis induced by ultraviolet B irradiation](https://pubmed.ncbi.nlm.nih.gov/21946069/) Hydroxyresveratrol · Food and Chemical Toxicology, 2011
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Poly-L-Lactic acid increases collagen gene expression and synthesis in cultured dermal fibroblast (Hs68) through the TGF-β/Smad pathway](https://pubmed.ncbi.nlm.nih.gov/36575891/) Lactic acid · Journal of Cosmetic Dermatology, 2023
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Application of Standardized Rosa damascena Stem Cell-Derived Exosomes in Dermatological Wound Healing and Scar Management: A Retrospective Case-Series Study with Long-Term Outcome Assessment](https://pubmed.ncbi.nlm.nih.gov/40733118/) Damascan rose · Pharmaceutics, 2025
- [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Moisturizing factors nmf, Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone, Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin, Panthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel water · Phytochemistry, 2001
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Moisturizing factors nmf · Molecules, 2021
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release](https://pubmed.ncbi.nlm.nih.gov/35929319/) Oenothera biennis oil · Biomaterials Advances, 2022
- [Efficacy of cosmetic formulations containing dispersion of liposome with magnesium ascorbyl phosphate, alpha-lipoic acid and kinetin](https://pubmed.ncbi.nlm.nih.gov/22236139/) Magnesium ascorbyl phosphate · Photochemistry and Photobiology, 2012
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Aloe barbadensis flower extract · Molecules, 2024
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial](https://pubmed.ncbi.nlm.nih.gov/40464749/) Ferulic acid · The Journal of Dermatological Treatment, 2025
- [Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol](https://pubmed.ncbi.nlm.nih.gov/23752031/) Sorbitol · Journal of Cosmetic Science, 2013
- [Depth-dependent hydration dynamics in human skin: Vehicle-controlled efficacy assessment of a functional 10% urea plus NMF moisturizer by near-infrared confocal spectroscopic imaging (KOSIM IR) and capacitance method complemented by volunteer perception](https://pubmed.ncbi.nlm.nih.gov/35034387/) Moisturizing factors nmf · Skin Research and Technology, 2022
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [Design and in vivo evaluation of emulgel formulations including green tea extract and rose oil](https://pubmed.ncbi.nlm.nih.gov/24451077/) Rosa damascena oil flower, Damascan rose · Acta Pharmaceutica, 2013
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/35745923/) Moringa oleifera seed oil · Polymers, 2022
- [Assessment of the efficacy and safety of a new complex skin cream in Asian women: A controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/28512843/) Hydroxyresveratrol · Journal of Cosmetic Dermatology, 2017
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [Highly efficient and compatible shampoo for use after hair transplant](https://pubmed.ncbi.nlm.nih.gov/26229498/) Chamomilla recutita oil flower matricaria oil flower · Clinical, Cosmetic and Investigational Dermatology, 2015
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
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- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/) Pha polyhydroxy acid · Cutis, 2004
- [Evolution of lipid composition in skin treated with blackcurrant seed oil](https://pubmed.ncbi.nlm.nih.gov/19456920/) Ribes nigrum seed oil · International Journal of Cosmetic Science, 1988
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
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- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025
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## The brands

- British skincare: [Medik8](https://lovi.care/skincare/nl/brands/medik8)
- Skincare: [Aēsop](https://lovi.care/skincare/nl/brands/aesop)

## More comparisons

- [SKIN1004 vs Medik8](https://lovi.care/skincare/nl/compare/skin1004-vs-medik8)
- [SKIN1004 vs Aēsop](https://lovi.care/skincare/nl/compare/skin1004-vs-aesop)
- [Anua vs Medik8](https://lovi.care/skincare/nl/compare/anua-vs-medik8)
- [Anua vs Aēsop](https://lovi.care/skincare/nl/compare/anua-vs-aesop)
- [Medicube vs Medik8](https://lovi.care/skincare/nl/compare/medicube-vs-medik8)
- [Medicube vs Aēsop](https://lovi.care/skincare/nl/compare/medicube-vs-aesop)
- [The Ordinary vs Medik8](https://lovi.care/skincare/nl/compare/the-ordinary-vs-medik8)
- [The Ordinary vs Aēsop](https://lovi.care/skincare/nl/compare/the-ordinary-vs-aesop)
- [Beauty of Joseon vs Medik8](https://lovi.care/skincare/nl/compare/beauty-of-joseon-vs-medik8)
- [Beauty of Joseon vs Aēsop](https://lovi.care/skincare/nl/compare/beauty-of-joseon-vs-aesop)
- [COSRX vs Medik8](https://lovi.care/skincare/nl/compare/cosrx-vs-medik8)
- [COSRX vs Aēsop](https://lovi.care/skincare/nl/compare/cosrx-vs-aesop)
- [CeraVe vs Medik8](https://lovi.care/skincare/nl/compare/cerave-vs-medik8)
- [CeraVe vs Aēsop](https://lovi.care/skincare/nl/compare/cerave-vs-aesop)
- [La Roche-Posay vs Medik8](https://lovi.care/skincare/nl/compare/la-roche-posay-vs-medik8)
- [La Roche-Posay vs Aēsop](https://lovi.care/skincare/nl/compare/la-roche-posay-vs-aesop)
- [Dr. Althea vs Medik8](https://lovi.care/skincare/nl/compare/dr-althea-vs-medik8)
- [Dr. Althea vs Aēsop](https://lovi.care/skincare/nl/compare/dr-althea-vs-aesop)
- [Some By Mi vs Medik8](https://lovi.care/skincare/nl/compare/some-by-mi-vs-medik8)
- [Some By Mi vs Aēsop](https://lovi.care/skincare/nl/compare/some-by-mi-vs-aesop)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/medik8-vs-aesop
- United Kingdom: https://lovi.care/skincare/uk/compare/medik8-vs-aesop
- Ireland: https://lovi.care/skincare/ie/compare/medik8-vs-aesop
- Germany: https://lovi.care/skincare/de/compare/medik8-vs-aesop
- France: https://lovi.care/skincare/fr/compare/medik8-vs-aesop
- Italy: https://lovi.care/skincare/it/compare/medik8-vs-aesop
- Netherlands: https://lovi.care/skincare/nl/compare/medik8-vs-aesop (this page)
- Spain: https://lovi.care/skincare/es/compare/medik8-vs-aesop
- Canada: https://lovi.care/skincare/ca/compare/medik8-vs-aesop
- Australia: https://lovi.care/skincare/au/compare/medik8-vs-aesop
- Singapore: https://lovi.care/skincare/sg/compare/medik8-vs-aesop
- Saudi Arabia: https://lovi.care/skincare/sa/compare/medik8-vs-aesop
- United Arab Emirates: https://lovi.care/skincare/ae/compare/medik8-vs-aesop