# Medicube vs Medik8

Page: https://lovi.care/skincare/nl/compare/medicube-vs-medik8

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Medicube and Medik8 are established skincare brands offering distinct approaches to daily regimens, with the former founded in South Korea in 2016 and the latter originating in Britain in 2009. The Korean brand is known for moisturizers, [serums](https://lovi.care/skincare/nl/ingredients/serum), toners, and masks featuring [niacinamide](https://lovi.care/skincare/nl/ingredients/niacinamide), [collagen](https://lovi.care/skincare/nl/ingredients/collagen), and [hyaluronic acid](https://lovi.care/skincare/nl/ingredients/hyaluronic-acid), whereas the British brand centers its serums, moisturizers, eye products, and toners around hyaluronic acid. Medicube suits oily acne-prone skin and oily skin best by balancing excess sebum and hydration, while Medik8 fits dry skin and dry sensitive skin best. The brands primarily differ in their regional origins, corporate ownership, and core ingredient philosophies.

Medicube is a Korean skincare brand founded in 2016 and owned by APR Corp..

[medicubereviews.co.uk](https://medicubereviews.co.uk/medicube/story/) [glossy.co](https://www.glossy.co/beauty/medicubes-founder-on-the-products-and-people-that-fueled-the-k-beauty-brands-booming-year/)

Medik8 is a British skincare brand founded in 2009 and owned by L'Oréal Groupe since 2025.

[loreal.com](https://www.loreal.com/en/press-release/group/l-oreal-groupe-to-acquire-a-majority-stake-in-medik8/) [medik8.com](https://www.medik8.com/pages/founders-story) [tracxn.com](https://tracxn.com/d/companies/medik8/__vqs3N9eL3EfvIq0IoeUPADts7CrlGbzm7kjy9M9QY8o)

This page compares some of the most popular Medicube and Medik8 products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg52c8f797fd).

### Popular Medicube vs Medik8 products

#### Medik8

- [Liquid Peptides](https://lovi.care/skincare/nl/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [€98.05 at Amazon](https://www.amazon.nl/dp/B0DSJNWVV6?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [CRYSTAL RETINAL 3](https://lovi.care/skincare/nl/p/medik8/crystal-retinal-3/for/mature-skin) — High fit — [€88.77 at Amazon](https://www.amazon.nl/dp/B07Y5P314G?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [C-Tetra Serum](https://lovi.care/skincare/nl/p/medik8/c-tetra-serum/for/dry-sensitive-skin) — Average fit — [€89.00 at Amazon](https://www.amazon.nl/dp/B0F6Z3V4RJ?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Bakuchiol Peptides](https://lovi.care/skincare/nl/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [€71.00 at Amazon](https://www.amazon.nl/dp/B0DP31336Z?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Crystal Retinal Ceramide Eye 3](https://lovi.care/skincare/nl/p/medik8/crystal-retinal-ceramide-eye-3/for/mature-skin) — High fit — [€53.00 at Lookfantastic](https://www.lookfantastic.nl/p/medik8-crystal-retinal-ceramide-eye-3-15ml/14271143/)
- [Oxy-R Peptides](https://lovi.care/skincare/nl/p/medik8/oxy-r-peptides/for/mature-skin) — Superior fit — [€75.25 at Amazon](https://www.amazon.nl/dp/B093R4NDJS?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Total Moisture Daily Facial Cream](https://lovi.care/skincare/nl/p/medik8/total-moisture-daily-facial-cream/for/mature-skin) — High fit — [€65.00 at Notino](https://www.notino.nl/medik8/total-moisture-gezichtscreme-met-hydraterende-werking/p-16269775/)
- [Hydr8 B5 Intense](https://lovi.care/skincare/nl/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [€64.50 at Notino](https://www.notino.nl/medik8/hydro8-b5-intense-hyaluronzuur-serum/p-16088887/)

#### Medicube

- [Zero Pore Pad](https://lovi.care/skincare/nl/p/medicube/zero-pore-pad/for/oily-skin) — Superior fit — [€16.99 at Amazon](https://www.amazon.nl/dp/B09V7Z4TJG?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [PDRN Pink Peptide Serum](https://lovi.care/skincare/nl/p/medicube/pdrn-pink-peptide-serum/for/mature-skin) — High fit — [€18.80 at Amazon](https://www.amazon.nl/dp/B0DCJ7952P?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Collagen Jelly Cream](https://lovi.care/skincare/nl/p/medicube/collagen-jelly-cream/for/mature-skin) — Superior fit — [€19.21 at Amazon](https://www.amazon.nl/dp/B0CM2PPNMW?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Collagen Night Wrapping Mask](https://lovi.care/skincare/nl/p/medicube/collagen-night-wrapping-mask/for/dry-skin) — High fit — [€16.99 at Amazon](https://www.amazon.nl/dp/B0F8HHJG25?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [PDRN Pink Collagen Gel Mask](https://lovi.care/skincare/nl/p/medicube/pdrn-pink-collagen-gel-mask/for/dry-sensitive-skin) — High fit — [€9.97 at Amazon](https://www.amazon.nl/dp/B0DBF52CLJ?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [DEEP VITA-C CAPSULE CREAM](https://lovi.care/skincare/nl/p/medicube/deep-vita-c-capsule-cream/for/sensitive-skin) — Average fit — [€17.19 at Amazon](https://www.amazon.nl/dp/B0D2Z3GGCY?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [TRIPLE COLLAGEN CREAM](https://lovi.care/skincare/nl/p/medicube/triple-collagen-cream/for/mature-skin) — Average fit — [€17.70 at Amazon](https://www.amazon.nl/dp/B0BPXT3GBN?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Zero Foam Cleanser](https://lovi.care/skincare/nl/p/medicube/zero-foam-cleanser/for/dry-skin) — Superior fit — [€13.46 at Amazon](https://www.amazon.nl/dp/B0DYTQ5GYQ?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)

## People Say

Medicube

Medik8

- Hydration and Moisture Mostly Mentioned Often Mentioned “skin feels bouncier and hydrated — Medicube PDRN Pink Peptide Serum” “glass skin — Medicube PDRN Pink Collagen Gel Mask” “woke up with baby soft skin — Medicube Collagen Jelly Cream” “Restores moisture — Medik8 Liquid Peptides”
- Gentle and Non-Irritating Sometimes Noted Mostly Mentioned “zero irritation or peeling — Medik8 CRYSTAL RETINAL 3” “only Vitamin C my sensitive skin can tolerate — Medik8 C-Tetra Serum” “Best retinol replacement — Medik8 Bakuchiol Peptides” “Did not cause any irritation — Medicube Red Foam Cleanser”
- Glow and Brightening Often Mentioned Often Mentioned “gave me instant glass skin — Medicube Collagen Jelly Cream” “woke up with glowing skin — Medicube Collagen Night Wrapping Mask” “I wake up glowing. It adds back that youthful bloom that I've lost. — Medik8 Sleep Glycolic” “unlocked a serious glow — Medik8 C-Tetra Serum”
- Texture and Skin Smoothing Often Mentioned Mostly Mentioned “absorbed effortlessly — Medik8 Total Moisture Daily Facial Cream” “My skin was smoother, my skin texture felt more resurfaced. — Medik8 Sleep Glycolic” “Absorbs fast — Medik8 Liquid Peptides” “gives my skin a smooth, glass-like finish — Medicube Zero Pore Pad”
- Cleansing and Pores Often Mentioned Rarely Noted “Pores drastically reduced — Medicube Zero Foam Cleanser” “Mochi-like foam — Medicube Zero Foam Cleanser” “Removes every trace of oil — Medicube Red Foam Cleanser” “pores feel cleaner — Medik8 Surface Radiance Cleanse”
- High Price Point Sometimes Noted Often Mentioned “tube is tiny for the price — Medicube Collagen Night Wrapping Mask” “price is steep — Medicube PDRN Pink Collagen Gel Mask” “price is a bit steep — Medicube Red Succinic Acid Peeling Pad” “Expensive per bottle — Medik8 Liquid Peptides”
- Sticky or Greasy Residue Often Mentioned Rarely Noted “too oily for my combination skin — Medik8 C-Tetra Serum” “Can feel sticky if over-applied — Medik8 Liquid Peptides” “Oily texture unpleasant — Medik8 Bakuchiol Peptides” “hair sticks to my face — Medicube Collagen Jelly Cream”

### Medicube vs Medik8 routines for dry skin

#### Medik8-focused routine

- Cleanser: [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [€21.95 at Amazon](https://www.amazon.nl/dp/B01N7T7JKJ?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/nl/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — [€16.89 at Amazon](https://www.amazon.nl/dp/B07B65NJLV?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/nl/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [€64.50 at Notino](https://www.notino.nl/medik8/hydro8-b5-intense-hyaluronzuur-serum/p-16088887/) — Morning · Evening · Once a week
- SPF: [Purito Daily Soft Touch Sunscreen](https://lovi.care/skincare/nl/p/purito/daily-soft-touch-sunscreen/for/dry-skin) — Superior fit — [€20.01 at Amazon](https://www.amazon.nl/dp/B0BS21D6SW?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/nl/p/medik8/press-and-glow/for/dry-skin) — Superior fit — [€41.99 at Amazon](https://www.amazon.nl/dp/B08KYV8H21?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Bakuchiol Peptides](https://lovi.care/skincare/nl/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [€71.00 at Amazon](https://www.amazon.nl/dp/B0DP31336Z?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [LANEIGE Water Sleeping Mask_EX](https://lovi.care/skincare/nl/p/laneige/water-sleeping-mask-ex/for/dry-skin) — Superior fit — [€33.90 at Amazon](https://www.amazon.nl/dp/B07XFLXW3S?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

#### Medicube-focused routine

- Cleanser: [Zero Foam Cleanser](https://lovi.care/skincare/nl/p/medicube/zero-foam-cleanser/for/dry-skin) — Superior fit — [€13.46 at Amazon](https://www.amazon.nl/dp/B0DYTQ5GYQ?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Triple Collagen Toner](https://lovi.care/skincare/nl/p/medicube/triple-collagen-toner/for/dry-skin) — High fit — [€12.45 at Amazon](https://www.amazon.nl/dp/B085VS2J3T?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [AGE-R Booster Gel](https://lovi.care/skincare/nl/p/medicube/age-r-booster-gel/for/dry-skin) — Superior fit — [€15.40 at Amazon](https://www.amazon.nl/dp/B0DNPWYZMT?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Purito Daily Soft Touch Sunscreen](https://lovi.care/skincare/nl/p/purito/daily-soft-touch-sunscreen/for/dry-skin) — Superior fit — [€20.01 at Amazon](https://www.amazon.nl/dp/B0BS21D6SW?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Zero Pore Pad](https://lovi.care/skincare/nl/p/medicube/zero-pore-pad/for/dry-skin) — Average fit — [€16.99 at Amazon](https://www.amazon.nl/dp/B09V7Z4TJG?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [One Day Exosome Shot 2000](https://lovi.care/skincare/nl/p/medicube/one-day-exosome-shot-2000/for/dry-skin) — High fit — [€17.12 at Amazon](https://www.amazon.nl/dp/B0DQCJ9T9N?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [Deep Peptide Radiance Mask](https://lovi.care/skincare/nl/p/medicube/deep-peptide-radiance-mask/for/dry-skin) — High fit — [€5.99 at Amazon](https://www.amazon.nl/dp/B0HGBQSTDY?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 98% fit](https://lovi.care/skincare/nl/skin/dry-skin)

### Medicube vs Medik8 routines for oily skin

#### Medicube-focused routine

- Cleanser: [Red Foam Cleanser](https://lovi.care/skincare/nl/p/medicube/red-foam-cleanser/for/oily-skin) — High fit — [€16.11 at Amazon](https://www.amazon.nl/dp/B0CVRD7N68?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Triple Collagen Toner](https://lovi.care/skincare/nl/p/medicube/triple-collagen-toner/for/oily-skin) — High fit — [€12.45 at Amazon](https://www.amazon.nl/dp/B085VS2J3T?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [AGE-R Booster Gel](https://lovi.care/skincare/nl/p/medicube/age-r-booster-gel/for/oily-skin) — High fit — [€15.40 at Amazon](https://www.amazon.nl/dp/B0DNPWYZMT?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — [€33.70 at Amazon](https://www.amazon.nl/dp/B0CF22FB86?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/oily-skin) — High fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Zero Pore Pad](https://lovi.care/skincare/nl/p/medicube/zero-pore-pad/for/oily-skin) — Superior fit — [€16.99 at Amazon](https://www.amazon.nl/dp/B09V7Z4TJG?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/nl/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€72.82 at Amazon](https://www.amazon.nl/dp/B0D1YJN279?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Zero Pore Blackhead Mud Mask](https://lovi.care/skincare/nl/p/medicube/zero-pore-blackhead-mud-mask/for/oily-skin) — Average fit — [€16.40 at Amazon](https://www.amazon.nl/dp/B0D1G7XF9X?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

#### Medik8-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/nl/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [€21.00 at Amazon](https://www.amazon.nl/dp/B01N1LL62W?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [€19.90 at Amazon](https://www.amazon.nl/dp/B08125WDCF?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/nl/p/medik8/hydr8-b5-intense/for/oily-skin) — High fit — [€64.50 at Notino](https://www.notino.nl/medik8/hydro8-b5-intense-hyaluronzuur-serum/p-16088887/) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — [€33.70 at Amazon](https://www.amazon.nl/dp/B0CF22FB86?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/oily-skin) — High fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/nl/p/medik8/press-and-glow/for/oily-skin) — Average fit — [€41.99 at Amazon](https://www.amazon.nl/dp/B08KYV8H21?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Oxy-R Peptides](https://lovi.care/skincare/nl/p/medik8/oxy-r-peptides/for/oily-skin) — High fit — [€75.25 at Amazon](https://www.amazon.nl/dp/B093R4NDJS?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/nl/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€72.82 at Amazon](https://www.amazon.nl/dp/B0D1YJN279?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/nl/p/vt-cosmetics/cica-purifying-mask/for/oily-skin) — High fit — [€15.72 at Amazon](https://www.amazon.nl/dp/B083X5R6VR?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 95% fit](https://lovi.care/skincare/nl/skin/oily-skin)

### Medicube vs Medik8 routines for combination skin

#### Medik8-focused routine

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/nl/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — [€16.50 at Amazon](https://www.amazon.nl/dp/B07RY6Q6QM?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [€36.00 at Amazon](https://www.amazon.nl/dp/B07P7VZ2J9?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/nl/p/medik8/hydr8-b5-intense/for/combination-skin) — High fit — [€64.50 at Notino](https://www.notino.nl/medik8/hydro8-b5-intense-hyaluronzuur-serum/p-16088887/) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — [€33.70 at Amazon](https://www.amazon.nl/dp/B0CF22FB86?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/combination-skin) — Superior fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/nl/p/medik8/press-and-glow/for/combination-skin) — High fit — [€41.99 at Amazon](https://www.amazon.nl/dp/B08KYV8H21?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Oxy-R Peptides](https://lovi.care/skincare/nl/p/medik8/oxy-r-peptides/for/combination-skin) — High fit — [€75.25 at Amazon](https://www.amazon.nl/dp/B093R4NDJS?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/nl/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — [€15.72 at Amazon](https://www.amazon.nl/dp/B083X5R6VR?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

#### Medicube-focused routine

- Cleanser: [Red Foam Cleanser](https://lovi.care/skincare/nl/p/medicube/red-foam-cleanser/for/combination-skin) — High fit — [€16.11 at Amazon](https://www.amazon.nl/dp/B0CVRD7N68?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Triple Collagen Toner](https://lovi.care/skincare/nl/p/medicube/triple-collagen-toner/for/combination-skin) — High fit — [€12.45 at Amazon](https://www.amazon.nl/dp/B085VS2J3T?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [AGE-R Booster Gel](https://lovi.care/skincare/nl/p/medicube/age-r-booster-gel/for/combination-skin) — High fit — [€15.40 at Amazon](https://www.amazon.nl/dp/B0DNPWYZMT?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — [€33.70 at Amazon](https://www.amazon.nl/dp/B0CF22FB86?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/combination-skin) — Superior fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Zero Pore Pad](https://lovi.care/skincare/nl/p/medicube/zero-pore-pad/for/combination-skin) — Superior fit — [€16.99 at Amazon](https://www.amazon.nl/dp/B09V7Z4TJG?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Mask: [Zero Pore Blackhead Mud Mask](https://lovi.care/skincare/nl/p/medicube/zero-pore-blackhead-mud-mask/for/combination-skin) — Average fit — [€16.40 at Amazon](https://www.amazon.nl/dp/B0D1G7XF9X?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 94% fit](https://lovi.care/skincare/nl/skin/combination-skin)

## Questions and answers

### Medicube or Medik8: which is better?

Medicube is better for hydration and pores, while Medik8 is better for being gentle and improving skin texture. For dry or sensitive skin, Medik8 has a Superior routine fit, whereas Medicube has a High fit.

### What is the difference between Medicube and Medik8?

Medicube is a South Korean brand founded in 2016 that focuses on hydration, moisture, and pore care, while Medik8 is a UK brand founded in 2009 that is known for being gentle and improving skin texture. For dry skin, Medik8 has a superior routine fit, whereas Medicube provides a high fit.

### Medicube or Medik8 for dry skin?

For dry skin, Medik8 has a Superior routine fit, while Medicube has a High routine fit. Both brands offer products that help provide deep hydration, though Medik8 is especially noted for being gentle and non-irritating.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Medicube or Medik8: which cleanser is better?

Medicube offers more options for cleansing, with several cleansers achieving high fit levels across various skin types, whereas Medik8 features Surface Radiance Cleanse as a standout choice.

### Which is more affordable, Medicube or Medik8?

Both brands face reviewer complaints about high prices, but Medicube has pricing issues noted specifically as a negative theme on this page. Medik8 is known for a high price point as well, making affordability a challenge for both options.

### Between Medicube and Medik8, which brand has a higher routine fit for dry sensitive skin?

Medik8 has a higher routine fit for dry sensitive skin, offering a Superior level compared to Medicube's High level.

### How do the founding years and corporate ownerships of Medicube and Medik8 compare?

Medicube was founded in South Korea in 2016 and is owned by APR Corp., whereas Medik8 was founded in the United Kingdom in 2009 and is owned by L'Oréal Groupe.

### Which brand uses fragrance in fewer of its products, Medicube or Medik8?

Medicube uses fragrance in fewer of its products than Medik8, featuring fragrance in 23 of its 25 products while Medik8 includes it in 11 of its 12 products on this page.

### Medicube or Medik8 for oily skin?

Both Medicube and Medik8 are good options for oily skin, as Lovi rates both brands as having a High routine fit for this skin type. Reviewers note that Medicube tends to do better for cleansing and pores, while Medik8 is often praised for its gentle [serums](https://lovi.care/skincare/nl/ingredients/serum).

### Medicube or Medik8: which moisturizer is better?

Medicube offers moisturizers like the [Collagen](https://lovi.care/skincare/nl/ingredients/collagen) Jelly Cream that help provide deep hydration and a radiant glow, while Medik8 provides options like Total Moisture Daily Facial Cream that are gentle and non-irritating.

### Medicube or Medik8 for sensitive skin?

Medik8 is a Superior fit for sensitive skin, whereas Medicube has a High fit level. Medik8 is frequently noted for gentle and non-irritating serums.

### Medicube or Medik8 for acne-prone skin?

Both Medicube and Medik8 are good options for acne-prone skin, as Lovi rates both brands as High for this skin type. Medicube focuses its routines best on acne-prone skin, oily skin, and oily acne-prone skin.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Efficacy of combined treatment with human adipose tissue stem cell-derived exosome-containing solution and microneedling for facial skin aging: A 12-week prospective, randomized, split-face study](https://pubmed.ncbi.nlm.nih.gov/37377400/) Exosome cica · Journal of Cosmetic Dermatology, 2023
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo](https://pubmed.ncbi.nlm.nih.gov/12823436/) Vitamin c derivatives · Experimental Dermatology, 2003
- [Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin](https://pubmed.ncbi.nlm.nih.gov/28330776/) Aha · Journal of Dermatological Science, 2017
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol vitamin e, Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics](https://pubmed.ncbi.nlm.nih.gov/35223163/) Collagen, Water-soluble collagen · Dermatology Practical & Conceptual, 2022
- [Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin](https://pubmed.ncbi.nlm.nih.gov/18492182/) Palmitoyl pentapeptide-4 · International Journal of Cosmetic Science, 2005
- [Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent](https://pubmed.ncbi.nlm.nih.gov/25648593/) Hydrolyzed opuntia ficus-indica flower extract · Molecules, 2015
- [Topical anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica](https://pubmed.ncbi.nlm.nih.gov/25821823/) Hydrolyzed opuntia ficus-indica flower extract · BioMed Research International, 2015
- [Tea tree oil reduces histamine-induced skin inflammation](https://pubmed.ncbi.nlm.nih.gov/12452873/) Tree · The British Journal of Dermatology, 2002
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract · International Journal of Molecular Medicine, 2016
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Centella asiatica extract, Madecassoside · Indian Journal of Pharmaceutical Sciences, 2016
- [Topical delivery of tetrahydrocurcumin lipid nanoparticles effectively inhibits skin inflammation: in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/29938544/) Tetrahydrodiferuloylmethane · Drug Development and Industrial Pharmacy, 2018
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Use of Collagen in Cosmetic Products](https://pubmed.ncbi.nlm.nih.gov/38534748/) Collagen, Water-soluble collagen · Current Issues in Molecular Biology, 2024
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Effect of Camellia japonica oil on human type I procollagen production and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/17386986/) Camellia japonica flower extract · Journal of Ethnopharmacology, 2007
- [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012
- [Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/26061570/) Hydrolyzed opuntia ficus-indica flower extract · Journal of Medicinal Food, 2015
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol vitamin e, Ferulic acid · Journal of Cosmetic Dermatology, 2020
- [Inhibitory effect of mulberroside A and its derivatives on melanogenesis induced by ultraviolet B irradiation](https://pubmed.ncbi.nlm.nih.gov/21946069/) Hydroxyresveratrol · Food and Chemical Toxicology, 2011
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Madecassoside · Journal of Alternative and Complementary Medicine, 2020
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [Protective effects of Camellia japonica flower extract against urban air pollutants](https://pubmed.ncbi.nlm.nih.gov/30691451/) Camellia japonica flower extract · BMC Complementary and Alternative Medicine, 2019
- [Quaternized carboxymethyl chitosan/organic montmorillonite nanocomposite as a novel cosmetic ingredient against skin aging](https://pubmed.ncbi.nlm.nih.gov/28732847/) Bentonite · Carbohydrate Polymers, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Development and photoprotective effect of a sunscreen containing the antioxidants Spirulina and dimethylmethoxy chromanol on sun-induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28341613/) Dimethylmethoxy chromanol · European Journal of Pharmaceutical Sciences, 2017
- [Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study](https://pubmed.ncbi.nlm.nih.gov/30548170/) Glycolic acid · Journal of Cosmetic Dermatology, 2019
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Hydrolyzed Collagen Induces an Anti-Inflammatory Response That Induces Proliferation of Skin Fibroblast and Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/36501011/) Collagen extract · Nutrients, 2022
- [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Moisturizing factors nmf, Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin, Panthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone, Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Acid-base combination principles for preparation of anti-acne dissolving microneedles loaded with azelaic acid and matrine](https://pubmed.ncbi.nlm.nih.gov/34284096/) Sophora angustifolia root extract, Sophora flavescens root extract · European Journal of Pharmaceutical Sciences, 2021
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Comparison of skin calming effects of cosmetic products containing 4-t-butylcyclohexanol or acetyl dipeptide-1 cetyl ester on capsaicin-induced facial stinging in volunteers with sensitive skin](https://pubmed.ncbi.nlm.nih.gov/26805418/) Lifting peptide · Journal of the European Academy of Dermatology and Venereology, 2016
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Moisturizing factors nmf · Molecules, 2021
- [Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release](https://pubmed.ncbi.nlm.nih.gov/35929319/) Oenothera biennis flower extract · Biomaterials Advances, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [New clinical approach in facial mild-moderate acne: Re-stabilization of skin microbiota balance with a topical biotechnological phytocomplex](https://pubmed.ncbi.nlm.nih.gov/39205505/) Succinic acid · Journal of Cosmetic Dermatology, 2024
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow bark extract · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow bark extract · Planta Medica, 2019
- [An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging](https://pubmed.ncbi.nlm.nih.gov/20883292/) Willow bark extract · Journal of Cosmetic Dermatology, 2010
- [A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/32390309/) Lauric acid · Dermatologic Therapy, 2020
- [The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging](https://pubmed.ncbi.nlm.nih.gov/36762391/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2023
- [Administration of skin care regimens containing β-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study](https://pubmed.ncbi.nlm.nih.gov/33128496/) Beta-glucan · Journal of Cosmetic Dermatology, 2021
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol](https://pubmed.ncbi.nlm.nih.gov/23752031/) Sorbitol · Journal of Cosmetic Science, 2013
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Aloe barbadensis flower extract · Molecules, 2024
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial](https://pubmed.ncbi.nlm.nih.gov/40464749/) Ferulic acid · The Journal of Dermatological Treatment, 2025
- [Gene expression profile of human follicle dermal papilla cells in response to Camellia japonica phytoplacenta extract](https://pubmed.ncbi.nlm.nih.gov/33410284/) Camellia japonica flower extract · FEBS Open Bio, 2021
- [Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects](https://pubmed.ncbi.nlm.nih.gov/39383579/) Palmitoyl tripeptide-5 · Colloids and Surfaces. B, Biointerfaces, 2025
- [Depth-dependent hydration dynamics in human skin: Vehicle-controlled efficacy assessment of a functional 10% urea plus NMF moisturizer by near-infrared confocal spectroscopic imaging (KOSIM IR) and capacitance method complemented by volunteer perception](https://pubmed.ncbi.nlm.nih.gov/35034387/) Moisturizing factors nmf · Skin Research and Technology, 2022
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [Comparison of topical purslane & topical 0.1% triamcinolone acetonide in the management of oral lichen planus - a double blinded clinical trial](https://pubmed.ncbi.nlm.nih.gov/37726676/) Portulaca oleracea extract · BMC Oral Health, 2023
- [Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores](https://pubmed.ncbi.nlm.nih.gov/17598025/) Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Anti-inflammatory and skin-hydrating properties of a dietary supplement and topical formulations containing oligomeric proanthocyanidins](https://pubmed.ncbi.nlm.nih.gov/17035721/) Grape seed extract · Skin Pharmacology and Physiology, 2007
- [Clinical study of Asian skin changes after application of a sunscreen formulation containing grape seed extract](https://pubmed.ncbi.nlm.nih.gov/35403355/) Grape seed extract · Journal of Cosmetic Dermatology, 2022
- [Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/35745923/) Moringa oleifera seed oil · Polymers, 2022
- [Assessment of the efficacy and safety of a new complex skin cream in Asian women: A controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/28512843/) Hydroxyresveratrol · Journal of Cosmetic Dermatology, 2017
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [Composition characterization and clinical efficacy study of a salmon egg extract](https://pubmed.ncbi.nlm.nih.gov/23738607/) Salmon egg extract · International Journal of Cosmetic Science, 2013
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Ethanolamines permeate slowly across human skin ex vivo, but cause severe skin irritation at low concentrations](https://pubmed.ncbi.nlm.nih.gov/31435711/) Ethanolamine · Archives of Toxicology, 2019
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
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- [The Therapeutic Effects of a Bentonite-Based Facial Mask With Alcea sulphurea Extract on Acne Severity and Patient Experience: Add-On Randomized Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/41347526/) Bentonite · Journal of Cosmetic Dermatology, 2025
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## The brands

- Korean skincare: [Medicube](https://lovi.care/skincare/nl/brands/medicube)
- British skincare: [Medik8](https://lovi.care/skincare/nl/brands/medik8)

## More comparisons

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- [SKIN1004 vs Medik8](https://lovi.care/skincare/nl/compare/skin1004-vs-medik8)
- [Anua vs Medicube](https://lovi.care/skincare/nl/compare/anua-vs-medicube)
- [Anua vs Medik8](https://lovi.care/skincare/nl/compare/anua-vs-medik8)
- [Medicube vs The Ordinary](https://lovi.care/skincare/nl/compare/medicube-vs-the-ordinary)
- [Medicube vs Beauty of Joseon](https://lovi.care/skincare/nl/compare/medicube-vs-beauty-of-joseon)
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- [Medicube vs CeraVe](https://lovi.care/skincare/nl/compare/medicube-vs-cerave)
- [Medicube vs La Roche-Posay](https://lovi.care/skincare/nl/compare/medicube-vs-la-roche-posay)
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- [Medicube vs Some By Mi](https://lovi.care/skincare/nl/compare/medicube-vs-some-by-mi)
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- [Medicube vs celimax](https://lovi.care/skincare/nl/compare/medicube-vs-celimax)
- [Medicube vs Purito](https://lovi.care/skincare/nl/compare/medicube-vs-purito)
- [Medicube vs Cetaphil](https://lovi.care/skincare/nl/compare/medicube-vs-cetaphil)
- [Medicube vs Paula's Choice](https://lovi.care/skincare/nl/compare/medicube-vs-paula-s-choice)
- [Medicube vs Neutrogena](https://lovi.care/skincare/nl/compare/medicube-vs-neutrogena)
- [Medicube vs Kiehl's](https://lovi.care/skincare/nl/compare/medicube-vs-kiehl-s)
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- [Medicube vs Dermalogica](https://lovi.care/skincare/nl/compare/medicube-vs-dermalogica)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/medicube-vs-medik8
- United Kingdom: https://lovi.care/skincare/uk/compare/medicube-vs-medik8
- Ireland: https://lovi.care/skincare/ie/compare/medicube-vs-medik8
- Germany: https://lovi.care/skincare/de/compare/medicube-vs-medik8
- France: https://lovi.care/skincare/fr/compare/medicube-vs-medik8
- Italy: https://lovi.care/skincare/it/compare/medicube-vs-medik8
- Netherlands: https://lovi.care/skincare/nl/compare/medicube-vs-medik8 (this page)
- Spain: https://lovi.care/skincare/es/compare/medicube-vs-medik8
- Canada: https://lovi.care/skincare/ca/compare/medicube-vs-medik8
- Australia: https://lovi.care/skincare/au/compare/medicube-vs-medik8
- Singapore: https://lovi.care/skincare/sg/compare/medicube-vs-medik8
- Saudi Arabia: https://lovi.care/skincare/sa/compare/medicube-vs-medik8
- United Arab Emirates: https://lovi.care/skincare/ae/compare/medicube-vs-medik8