# ISDIN vs MAËLYS

Page: https://lovi.care/skincare/nl/compare/isdin-vs-maelys

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

ISDIN and MAËLYS are distinct skincare collections that offer thoughtful solutions for varied complexions. The Spanish brand founded in 1975 provides elegant moisturizers, advanced sunscreens, restorative [serums](https://lovi.care/skincare/nl/ingredients/serum), and targeted eye products that suit dry skin and sensitive skin best, while the other label is known for targeted serums and advanced formulas that suit all skin types best. They differ primarily in their core formulation focus and ideal skin matches, with standout options including Fusion [Water](https://lovi.care/skincare/nl/ingredients/water), Eryfotona Actinica, and K-Ox Eyes from the first, and TOO-FINE alongside the RE-LURE Tight & Tone Body Serum from the second. Through these specialized remedies, both collections deliver reliable daily support that maintains a healthy and balanced complexion.

ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/) [beautymatter.com](https://beautymatter.com/articles/puig-to-take-full-ownership-of-isdin-in-1-39-billion-deal) [uploads.puig.com](https://uploads.puig.com/uploads/Puig_NP_Sept_14_EN_fc21e2f47a.pdf)

This page compares some of the most popular ISDIN and MAËLYS products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgf624effac1).

### Popular ISDIN vs MAËLYS products

#### ISDIN

- [Eryfotona Actinica](https://lovi.care/skincare/nl/p/isdin/eryfotona-actinica/for/mature-skin) — Superior fit — [€32.43 at Amazon](https://www.amazon.nl/dp/B0875W6QQG?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Fusion Water](https://lovi.care/skincare/nl/p/isdin/fusion-water/for/dry-sensitive-skin) — Superior fit — [€24.98 at Amazon](https://www.amazon.nl/dp/B09SQF23RV?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [K-Ox Eyes](https://lovi.care/skincare/nl/p/isdin/k-ox-eyes/for/dry-skin) — High fit — [€50.91 at Amazon](https://www.amazon.nl/dp/B01BMLQ4JQ?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Hyaluronic Concentrate](https://lovi.care/skincare/nl/p/isdin/hyaluronic-concentrate/for/sensitive-skin) — High fit
- [Hyaluronic Moisture](https://lovi.care/skincare/nl/p/isdin/hyaluronic-moisture/for/dry-sensitive-skin) — Average fit
- [Flavo-C Serum](https://lovi.care/skincare/nl/p/isdin/flavo-c-serum/for/sensitive-skin) — High fit — [€45.97 at Amazon](https://www.amazon.nl/dp/B01BMLQ086?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Uradin Lotion 10](https://lovi.care/skincare/nl/p/isdin/uradin-lotion-10/for/dry-skin) — High fit
- [Retinal Intense Serum](https://lovi.care/skincare/nl/p/isdin/retinal-intense-serum/for/acne-prone-skin) — High fit — [€63.01 at Amazon](https://www.amazon.nl/dp/B0BD9DK6SC?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)

#### MAËLYS

- [TOO-FINE](https://lovi.care/skincare/nl/p/maelys/too-fine/for/sensitive-skin) — Low fit
- [RE-LURE Tight & Tone Body Serum](https://lovi.care/skincare/nl/p/maelys/re-lure-tight-and-tone-body-serum/for/dry-sensitive-skin) — Average fit

## Questions and answers

### ISDIN or MAËLYS: which is better?

ISDIN is the better choice because the products on this page have significantly higher Lovi fit levels across multiple skin types, whereas MAËLYS products mostly show low or average fits. Topical [hyaluronic acid](https://lovi.care/skincare/nl/ingredients/hyaluronic-acid) helps improve skin quality and signs of skin aging.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What is the difference between ISDIN and MAËLYS?

ISDIN offers a broad selection of sunscreens and moisturizers with High to Superior Lovi fit levels for dry, sensitive, and acne-prone skin types, whereas the products on this page for MAËLYS show Low or Average fit levels. Antioxidants like [vitamin C](https://lovi.care/skincare/nl/ingredients/vitamin-c) help brighten the skin, while hyaluronic acid helps retain moisture.

[Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which is more affordable, ISDIN or MAËLYS?

ISDIN has a high price point among the products on this page, while pricing details for MAËLYS are not provided.

### Which causes fewer breakouts, ISDIN or MAËLYS?

ISDIN is the better choice for acne-prone skin because the products on this page achieve High fit levels for that skin type, whereas MAËLYS products are rated Low. Topical hyaluronic acid and antioxidants help support skin quality and protect against damage, which may reduce irritation and breakouts.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

### Between ISDIN and MAËLYS, which brand was founded earlier?

ISDIN was founded earlier in 1975, while MAËLYS was founded in 2017.

### Which brand has more fragrance-free products listed on the page?

ISDIN has more fragrance-free products listed on the page, with three fragrance-free items compared to MAËLYS, which has only one.

### Which brand's products achieve a Superior fit level for mature skin?

ISDIN achieves a Superior fit level for mature skin with Eryfotona Actinica, while MAËLYS products on this page are unlikely to reach that level for mature skin.

## Research behind their key ingredients

- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Antioxidants · Drug Delivery, 2017
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Regulatory effects of Lactobacillus plantarum-GMNL6 on human skin health by improving skin microbiome](https://pubmed.ncbi.nlm.nih.gov/33526970/) Lactobacillus · International Journal of Medical Sciences, 2021
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Antiaging efficacy of melatonin-based day and night creams: a randomized, split-face, assessor-blinded proof-of-concept trial](https://pubmed.ncbi.nlm.nih.gov/29416368/) Melatonin · Clinical, Cosmetic and Investigational Dermatology, 2018
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Efficacy of probiotic-derived lotion from Lactobacillus paracasei MSMC 39-1 in mild to moderate acne vulgaris, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/35384257/) Lactobacillus · Journal of Cosmetic Dermatology, 2022
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Butyl methoxydibenzoylmethane · European Journal of Pharmaceutical Sciences, 2023
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Evaluation of a retinol containing topical treatment to improve signs of neck aging](https://pubmed.ncbi.nlm.nih.gov/37461826/) Glaucine · Journal of Cosmetic Dermatology, 2023
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl salicylate · Archives of Dermatological Research, 2024
- [The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration](https://pubmed.ncbi.nlm.nih.gov/38140770/) Lens esculenta seed extract · Journal of Cosmetic Dermatology, 2024
- [Clinical and histologic findings after use of a novel combined retinol, tripeptide, and glaucine containing cream in the treatment of photo-aged skin](https://pubmed.ncbi.nlm.nih.gov/37584260/) Glaucine · Journal of Cosmetic Dermatology, 2023
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · International Journal of Cosmetic Science, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025

## The brands

- Spanish skincare: [ISDIN](https://lovi.care/skincare/nl/brands/isdin)
- Skincare: [MAËLYS](https://lovi.care/skincare/nl/brands/maelys)

## More comparisons

- [SKIN1004 vs ISDIN](https://lovi.care/skincare/nl/compare/skin1004-vs-isdin)
- [SKIN1004 vs MAËLYS](https://lovi.care/skincare/nl/compare/skin1004-vs-maelys)
- [Anua vs ISDIN](https://lovi.care/skincare/nl/compare/anua-vs-isdin)
- [Anua vs MAËLYS](https://lovi.care/skincare/nl/compare/anua-vs-maelys)
- [Medicube vs ISDIN](https://lovi.care/skincare/nl/compare/medicube-vs-isdin)
- [Medicube vs MAËLYS](https://lovi.care/skincare/nl/compare/medicube-vs-maelys)
- [The Ordinary vs ISDIN](https://lovi.care/skincare/nl/compare/the-ordinary-vs-isdin)
- [The Ordinary vs MAËLYS](https://lovi.care/skincare/nl/compare/the-ordinary-vs-maelys)
- [Beauty of Joseon vs ISDIN](https://lovi.care/skincare/nl/compare/beauty-of-joseon-vs-isdin)
- [Beauty of Joseon vs MAËLYS](https://lovi.care/skincare/nl/compare/beauty-of-joseon-vs-maelys)
- [COSRX vs ISDIN](https://lovi.care/skincare/nl/compare/cosrx-vs-isdin)
- [COSRX vs MAËLYS](https://lovi.care/skincare/nl/compare/cosrx-vs-maelys)
- [CeraVe vs ISDIN](https://lovi.care/skincare/nl/compare/cerave-vs-isdin)
- [CeraVe vs MAËLYS](https://lovi.care/skincare/nl/compare/cerave-vs-maelys)
- [La Roche-Posay vs ISDIN](https://lovi.care/skincare/nl/compare/la-roche-posay-vs-isdin)
- [La Roche-Posay vs MAËLYS](https://lovi.care/skincare/nl/compare/la-roche-posay-vs-maelys)
- [Dr. Althea vs ISDIN](https://lovi.care/skincare/nl/compare/dr-althea-vs-isdin)
- [Dr. Althea vs MAËLYS](https://lovi.care/skincare/nl/compare/dr-althea-vs-maelys)
- [Some By Mi vs ISDIN](https://lovi.care/skincare/nl/compare/some-by-mi-vs-isdin)
- [Some By Mi vs MAËLYS](https://lovi.care/skincare/nl/compare/some-by-mi-vs-maelys)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/isdin-vs-maelys
- United Kingdom: https://lovi.care/skincare/uk/compare/isdin-vs-maelys
- Ireland: https://lovi.care/skincare/ie/compare/isdin-vs-maelys
- Germany: https://lovi.care/skincare/de/compare/isdin-vs-maelys
- France: https://lovi.care/skincare/fr/compare/isdin-vs-maelys
- Italy: https://lovi.care/skincare/it/compare/isdin-vs-maelys
- Netherlands: https://lovi.care/skincare/nl/compare/isdin-vs-maelys (this page)
- Spain: https://lovi.care/skincare/es/compare/isdin-vs-maelys
- Canada: https://lovi.care/skincare/ca/compare/isdin-vs-maelys
- Australia: https://lovi.care/skincare/au/compare/isdin-vs-maelys
- Singapore: https://lovi.care/skincare/sg/compare/isdin-vs-maelys
- Saudi Arabia: https://lovi.care/skincare/sa/compare/isdin-vs-maelys
- United Arab Emirates: https://lovi.care/skincare/ae/compare/isdin-vs-maelys