# Good Molecules vs SK-II

Page: https://lovi.care/skincare/nl/compare/good-molecules-vs-sk-ii

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Good Molecules and SK-II are skincare brands founded in the United States and Japan that offer thoughtfully formulated [serums](https://lovi.care/skincare/nl/ingredients/serum), moisturizers, and more for dry skin and acne-prone skin. The American brand relies on [glycerin](https://lovi.care/skincare/nl/ingredients/glycerin) and [hyaluronic acid](https://lovi.care/skincare/nl/ingredients/hyaluronic-acid), whereas the Japanese brand anchors its products in its signature ingredient, pitera. While both manufacturers suit similar complexions, they differ through their distinct heritage, standout treatments, and core active components.

Good Molecules is an American skincare brand founded in 2019 and owned by Beautylish, Inc..

[beautymatter.com](https://beautymatter.com/articles/aria-growth-partners-makes-investment-in-good-molecules) [goodmolecules.com](https://www.goodmolecules.com/about) [pitchbook.com](https://pitchbook.com/profiles/company/458272-45) [preqin.com](https://www.preqin.com/data/profile/asset/good-molecules--llc-/802471)

SK-II is a Japanese skincare brand founded in 1980 and owned by The Procter & Gamble Company since 1991.

[en.wikipedia.org](https://en.wikipedia.org/wiki/SK-II) [discoversk-ii.wixsite.com](https://discoversk-ii.wixsite.com/home/brand-history) [glossy.co](https://www.glossy.co/beauty/despite-strong-results-in-beauty-in-the-first-quarter-pg-will-eliminate-thousands-of-jobs/)

This page compares some of the most popular Good Molecules and SK-II products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pga3bc3815d4).

### Popular Good Molecules vs SK-II products

#### SK-II

- [Facial Treatment Essence](https://lovi.care/skincare/nl/p/sk-ii/facial-treatment-essence/for/dry-skin) — High fit — [€116.00 at Notino](https://www.notino.nl/sk-ii/facial-treatment-gezichtsserum-tegen-huidveroudering/p-16254932/)
- [Facial Treatment Mask](https://lovi.care/skincare/nl/p/sk-ii/facial-treatment-mask/for/dry-skin) — High fit — [€159.00 at Notino](https://www.notino.nl/sk-ii/facial-treatment-verstevigende-gezichtsmasker/p-16254656/)
- [Facial Treatment Clear Lotion](https://lovi.care/skincare/nl/p/sk-ii/facial-treatment-clear-lotion/for/oily-skin) — High fit
- [Skinpower Advanced Cream](https://lovi.care/skincare/nl/p/sk-ii/skinpower-advanced-cream/for/mature-skin) — High fit
- [Genoptics Ultraura Essence](https://lovi.care/skincare/nl/p/sk-ii/genoptics-ultraura-essence/for/acne-prone-skin) — Superior fit — [€268.00 at Notino](https://www.notino.nl/sk-ii/genoptics-ultraura-essence-verhelderende-serum/p-16254642/)
- [Facial Treatment Cleansing Oil](https://lovi.care/skincare/nl/p/sk-ii/facial-treatment-cleansing-oil/for/dry-skin) — High fit — [€88.50 at Notino](https://www.notino.nl/sk-ii/facial-treatment-cleansing-oil-reinigingsolie-voor-alle-huidtypen/p-16324436/)
- [Genoptics Spot Essence](https://lovi.care/skincare/nl/p/sk-ii/genoptics-spot-essence/for/dark-spots) — Average fit

#### Good Molecules

- [Discoloration Correcting Serum](https://lovi.care/skincare/nl/p/good-molecules/discoloration-correcting-serum/for/dry-skin) — High fit — [€41.90 at Amazon](https://www.amazon.nl/dp/B0BX32CXP6?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Hyaluronic Acid Serum](https://lovi.care/skincare/nl/p/good-molecules/hyaluronic-acid-serum/for/dry-skin) — Superior fit — [€16.98 at Amazon](https://www.amazon.nl/dp/B08TM8DLFJ?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Gentle Retinol Cream](https://lovi.care/skincare/nl/p/good-molecules/gentle-retinol-cream/for/mature-skin) — High fit
- [Niacinamide Serum](https://lovi.care/skincare/nl/p/good-molecules/niacinamide-serum/for/oily-skin) — Average fit — [€17.96 at Amazon](https://www.amazon.nl/dp/B08R994Q1L?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Niacinamide Brightening Toner](https://lovi.care/skincare/nl/p/good-molecules/niacinamide-brightening-toner/for/dry-skin) — High fit — [€55.91 at Amazon](https://www.amazon.nl/dp/B08C2BLPD2?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [PIMPLE PATCHES](https://lovi.care/skincare/nl/p/good-molecules/pimple-patches/for/acne-prone-skin) — Average fit
- [Yerba Mate Wake Up Eye Gel](https://lovi.care/skincare/nl/p/good-molecules/yerba-mate-wake-up-eye-gel/for/mature-skin) — Superior fit — [€13.86 at Amazon](https://www.amazon.nl/dp/B091NJQ29P?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Lightweight Daily Moisturizer](https://lovi.care/skincare/nl/p/good-molecules/lightweight-daily-moisturizer/for/dry-skin) — Superior fit — [€21.59 at Amazon](https://www.amazon.nl/dp/B0C26KZ7G6?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)

## People Say

Good Molecules

SK-II

- Texture and Consistency Mostly Mentioned Mostly Mentioned “absorbs quickly... zero irritation or tacky feeling — Good Molecules Discoloration Correcting Serum” “practically invisible on skin — Good Molecules PIMPLE PATCHES” “drinks right into the skin — SK-II Facial Treatment Essence” “pores became miraculously invisible — SK-II Facial Treatment Mask”
- Advanced Performance and Extras Often Mentioned Mostly Mentioned “Removes leftover dirt — SK-II Facial Treatment Clear Lotion” “Dissolves waterproof mascara, melts stubborn makeup, removes sunscreen easily. — SK-II Facial Treatment Cleansing Oil” “Reduced sun spots — SK-II Genoptics Spot Essence” “scar on your chin doesn't look nearly as noticeable — Good Molecules Discoloration Correcting Serum”
- Value and Pricing Mostly Mentioned Not noted “best value for money — Good Molecules Hyaluronic Acid Serum” “great value — Good Molecules Niacinamide Serum”
- Brightening and Radiance Sometimes Noted Mostly Mentioned “gives a glass skin look — SK-II Facial Treatment Essence” “leaves me with a red carpet glow — SK-II Facial Treatment Mask” “Skin looks brighter — SK-II Genoptics Spot Essence” “skin looks more radiant — Good Molecules Niacinamide Brightening Toner”
- Hydration and Plumping Often Mentioned Mostly Mentioned “flooded my skin with moisture — SK-II Facial Treatment Mask” “skin feels deeply hydrated, plump, and smoother — SK-II Skinpower Advanced Cream” “Leaves skin soft, feels moisturized, does not dry out skin. — SK-II Facial Treatment Cleansing Oil” “skin appears smooth and supple — Good Molecules Hyaluronic Acid Serum”
- Gentle and Sensitive Care Often Mentioned Rarely Noted “no skin purging — Good Molecules Gentle Retinol Cream” “Non-abrasive, suitable for sensitive skin, no stinging — Good Molecules Pineapple Exfoliating Powder” “leaves my face feeling clean without the drying — Good Molecules Hydrating Facial Cleansing Gel” “Great for sensitive — SK-II Genoptics Spot Essence”
- High Price and Cost Not noted Mostly Mentioned “way too expensive — SK-II Facial Treatment Essence”
- Slow or Ineffective Results Often Mentioned Often Mentioned “didn't really see a difference — Good Molecules Discoloration Correcting Serum” “dried my skin out — Good Molecules Hyaluronic Acid Serum” “did absolutely nothing — SK-II Facial Treatment Essence” “No visible difference — SK-II Facial Treatment Clear Lotion”
- Scent and Fragrance Complaints Sometimes Noted Often Mentioned “Strong bergamot smell — Good Molecules Super Peptide Serum” “weird faint smell — Good Molecules Gentle Retinol Cream” “smelled of glycolic acid — Good Molecules Overnight Exfoliating Treatment” “smells like dirty feet — SK-II Facial Treatment Essence”

### Good Molecules vs SK-II routines for dry skin

#### Good Molecules-focused routine

- Cleanser: [Hydrating Facial Cleansing Gel](https://lovi.care/skincare/nl/p/good-molecules/hydrating-facial-cleansing-gel/for/dry-skin) — High fit — [€46.05 at Amazon](https://www.amazon.nl/dp/B0CMGJ1NW4?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/nl/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — [€16.89 at Amazon](https://www.amazon.nl/dp/B07B65NJLV?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Lightweight Daily Moisturizer](https://lovi.care/skincare/nl/p/good-molecules/lightweight-daily-moisturizer/for/dry-skin) — Superior fit — [€21.59 at Amazon](https://www.amazon.nl/dp/B0C26KZ7G6?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Sheer Mineral Sunscreen SPF 30](https://lovi.care/skincare/nl/p/good-molecules/sheer-mineral-sunscreen-spf-30/for/dry-skin) — Superior fit — [€81.42 at Amazon](https://www.amazon.nl/dp/B0BNC52HLN?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [ROUND LAB 1025 Dokdo Cleansing Water](https://lovi.care/skincare/nl/p/round-lab/1025-dokdo-cleansing-water/for/dry-skin) — Superior fit — [€13.99 at Amazon](https://www.amazon.nl/dp/B0BPB4KMJP?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Daily Brightening Serum](https://lovi.care/skincare/nl/p/good-molecules/daily-brightening-serum/for/dry-skin) — High fit — [€47.00 at Amazon](https://www.amazon.nl/dp/B0BXY8FDZY?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Nourishing Mask: [LANEIGE Water Sleeping Mask_EX](https://lovi.care/skincare/nl/p/laneige/water-sleeping-mask-ex/for/dry-skin) — Superior fit — [€33.90 at Amazon](https://www.amazon.nl/dp/B07XFLXW3S?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

#### SK-II-focused routine

- Cleanser: [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/nl/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [€21.95 at Amazon](https://www.amazon.nl/dp/B01N7T7JKJ?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Dear, Klairs Supple Preparation Unscented Toner](https://lovi.care/skincare/nl/p/dear-klairs/supple-preparation-unscented-toner/for/dry-skin) — Superior fit — [€16.89 at Amazon](https://www.amazon.nl/dp/B07B65NJLV?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Facial Treatment Essence](https://lovi.care/skincare/nl/p/sk-ii/facial-treatment-essence/for/dry-skin) — High fit — [€116.00 at Notino](https://www.notino.nl/sk-ii/facial-treatment-gezichtsserum-tegen-huidveroudering/p-16254932/) — Morning · Evening · Once a week
- SPF: [Purito Daily Soft Touch Sunscreen](https://lovi.care/skincare/nl/p/purito/daily-soft-touch-sunscreen/for/dry-skin) — Superior fit — [€20.01 at Amazon](https://www.amazon.nl/dp/B0BS21D6SW?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Facial Treatment Cleansing Oil](https://lovi.care/skincare/nl/p/sk-ii/facial-treatment-cleansing-oil/for/dry-skin) — High fit — [€88.50 at Notino](https://www.notino.nl/sk-ii/facial-treatment-cleansing-oil-reinigingsolie-voor-alle-huidtypen/p-16324436/) — Evening · Once a week
- Cleansing Toner: [ROUND LAB 1025 Dokdo Cleansing Water](https://lovi.care/skincare/nl/p/round-lab/1025-dokdo-cleansing-water/for/dry-skin) — Superior fit — [€13.99 at Amazon](https://www.amazon.nl/dp/B0BPB4KMJP?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Genoptics Ultraura Essence](https://lovi.care/skincare/nl/p/sk-ii/genoptics-ultraura-essence/for/dry-skin) — High fit — [€268.00 at Notino](https://www.notino.nl/sk-ii/genoptics-ultraura-essence-verhelderende-serum/p-16254642/) — Evening · Once a week
- Nourishing Mask: [Facial Treatment Mask](https://lovi.care/skincare/nl/p/sk-ii/facial-treatment-mask/for/dry-skin) — High fit — [€159.00 at Notino](https://www.notino.nl/sk-ii/facial-treatment-verstevigende-gezichtsmasker/p-16254656/) — Once a week

[See multi-brand routine · 98% fit](https://lovi.care/skincare/nl/skin/dry-skin)

### Good Molecules vs SK-II routines for oily skin

#### Good Molecules-focused routine

- Cleanser: [Hydrating Facial Cleansing Gel](https://lovi.care/skincare/nl/p/good-molecules/hydrating-facial-cleansing-gel/for/oily-skin) — Average fit — [€46.05 at Amazon](https://www.amazon.nl/dp/B0CMGJ1NW4?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [€19.90 at Amazon](https://www.amazon.nl/dp/B08125WDCF?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hyaluronic Acid Serum](https://lovi.care/skincare/nl/p/good-molecules/hyaluronic-acid-serum/for/oily-skin) — High fit — [€16.98 at Amazon](https://www.amazon.nl/dp/B08TM8DLFJ?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Sheer Mineral Sunscreen SPF 30](https://lovi.care/skincare/nl/p/good-molecules/sheer-mineral-sunscreen-spf-30/for/oily-skin) — High fit — [€81.42 at Amazon](https://www.amazon.nl/dp/B0BNC52HLN?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/oily-skin) — High fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/nl/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [€18.05 at Amazon](https://www.amazon.nl/dp/B09SN5B88W?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Overnight Exfoliating Treatment](https://lovi.care/skincare/nl/p/good-molecules/overnight-exfoliating-treatment/for/oily-skin) — Superior fit — [€22.99 at Amazon](https://www.amazon.nl/dp/B08TMDRF1L?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/nl/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€72.82 at Amazon](https://www.amazon.nl/dp/B0D1YJN279?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/nl/p/vt-cosmetics/cica-purifying-mask/for/oily-skin) — High fit — [€15.72 at Amazon](https://www.amazon.nl/dp/B083X5R6VR?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

#### SK-II-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/nl/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [€21.00 at Amazon](https://www.amazon.nl/dp/B01N1LL62W?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/nl/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [€19.90 at Amazon](https://www.amazon.nl/dp/B08125WDCF?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Facial Treatment Essence](https://lovi.care/skincare/nl/p/sk-ii/facial-treatment-essence/for/oily-skin) — Average fit — [€116.00 at Notino](https://www.notino.nl/sk-ii/facial-treatment-gezichtsserum-tegen-huidveroudering/p-16254932/) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-skin) — Superior fit — [€33.70 at Amazon](https://www.amazon.nl/dp/B0CF22FB86?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Facial Treatment Cleansing Oil](https://lovi.care/skincare/nl/p/sk-ii/facial-treatment-cleansing-oil/for/oily-skin) — Average fit — [€88.50 at Notino](https://www.notino.nl/sk-ii/facial-treatment-cleansing-oil-reinigingsolie-voor-alle-huidtypen/p-16324436/) — Evening · Once a week
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/nl/p/pixi/glow-tonic/for/oily-skin) — Superior fit — [€18.05 at Amazon](https://www.amazon.nl/dp/B09SN5B88W?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Genoptics Ultraura Essence](https://lovi.care/skincare/nl/p/sk-ii/genoptics-ultraura-essence/for/oily-skin) — High fit — [€268.00 at Notino](https://www.notino.nl/sk-ii/genoptics-ultraura-essence-verhelderende-serum/p-16254642/) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/nl/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [€72.82 at Amazon](https://www.amazon.nl/dp/B0D1YJN279?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/nl/p/vt-cosmetics/cica-purifying-mask/for/oily-skin) — High fit — [€15.72 at Amazon](https://www.amazon.nl/dp/B083X5R6VR?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 95% fit](https://lovi.care/skincare/nl/skin/oily-skin)

### Good Molecules vs SK-II routines for combination skin

#### Good Molecules-focused routine

- Cleanser: [Hydrating Facial Cleansing Gel](https://lovi.care/skincare/nl/p/good-molecules/hydrating-facial-cleansing-gel/for/combination-skin) — Average fit — [€46.05 at Amazon](https://www.amazon.nl/dp/B0CMGJ1NW4?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [€36.00 at Amazon](https://www.amazon.nl/dp/B07P7VZ2J9?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hyaluronic Acid Serum](https://lovi.care/skincare/nl/p/good-molecules/hyaluronic-acid-serum/for/combination-skin) — High fit — [€16.98 at Amazon](https://www.amazon.nl/dp/B08TM8DLFJ?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Sheer Mineral Sunscreen SPF 30](https://lovi.care/skincare/nl/p/good-molecules/sheer-mineral-sunscreen-spf-30/for/combination-skin) — High fit — [€81.42 at Amazon](https://www.amazon.nl/dp/B0BNC52HLN?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/nl/p/missha/ultra-hyalon-cleansing-cream/for/combination-skin) — Superior fit — [€11.83 at Amazon](https://www.amazon.nl/dp/B084Q16G8D?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/nl/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [€16.99 at Amazon](https://www.amazon.nl/dp/B09V7Z4TJG?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Overnight Exfoliating Treatment](https://lovi.care/skincare/nl/p/good-molecules/overnight-exfoliating-treatment/for/combination-skin) — Superior fit — [€22.99 at Amazon](https://www.amazon.nl/dp/B08TMDRF1L?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/nl/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — [€15.72 at Amazon](https://www.amazon.nl/dp/B083X5R6VR?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

#### SK-II-focused routine

- Cleanser: [Dr. Althea Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/nl/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/combination-skin) — Superior fit — [€16.50 at Amazon](https://www.amazon.nl/dp/B07RY6Q6QM?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/nl/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [€36.00 at Amazon](https://www.amazon.nl/dp/B07P7VZ2J9?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Facial Treatment Essence](https://lovi.care/skincare/nl/p/sk-ii/facial-treatment-essence/for/combination-skin) — High fit — [€116.00 at Notino](https://www.notino.nl/sk-ii/facial-treatment-gezichtsserum-tegen-huidveroudering/p-16254932/) — Morning · Evening · Once a week
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/nl/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/combination-skin) — Superior fit — [€33.70 at Amazon](https://www.amazon.nl/dp/B0CF22FB86?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Facial Treatment Cleansing Oil](https://lovi.care/skincare/nl/p/sk-ii/facial-treatment-cleansing-oil/for/combination-skin) — Average fit — [€88.50 at Notino](https://www.notino.nl/sk-ii/facial-treatment-cleansing-oil-reinigingsolie-voor-alle-huidtypen/p-16324436/) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/nl/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [€16.99 at Amazon](https://www.amazon.nl/dp/B09V7Z4TJG?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Serum or Treatment: [Genoptics Ultraura Essence](https://lovi.care/skincare/nl/p/sk-ii/genoptics-ultraura-essence/for/combination-skin) — High fit — [€268.00 at Notino](https://www.notino.nl/sk-ii/genoptics-ultraura-essence-verhelderende-serum/p-16254642/) — Evening · Once a week
- Cleansing Mask: [VT Cosmetics Cica Purifying Mask](https://lovi.care/skincare/nl/p/vt-cosmetics/cica-purifying-mask/for/combination-skin) — High fit — [€15.72 at Amazon](https://www.amazon.nl/dp/B083X5R6VR?tag=lovi-care-web-routine0d5-21&linkCode=osi&th=1&psc=1) — Once a week

[See multi-brand routine · 94% fit](https://lovi.care/skincare/nl/skin/combination-skin)

## Questions and answers

### Good Molecules or SK-II: which is better?

Good Molecules offers better value and sensitive skin care, while SK-II provides superior brightening, hydration, and advanced performance based on the products on this page.

### What is the difference between Good Molecules and SK-II?

Good Molecules and SK-II both offer effective products for various skin types, but Good Molecules is more affordable and better suited for gentle and sensitive care, while SK-II excels in advanced performance, brightening, and hydration.

### Good Molecules or SK-II for dry skin?

Both Good Molecules and SK-II achieve a Superior routine fit for dry skin. Reviewers often mention Good Molecules for offering affordable and hydrating moisturizers, while the products on this page list no fragrance in their ingredients.

### Good Molecules or SK-II: which moisturizer is better?

Both brands offer solid moisturizer choices, with Good Molecules providing affordable and hydrating moisturizers and SK-II delivering advanced hydration and plumping. [Hyaluronic acid](https://lovi.care/skincare/nl/ingredients/hyaluronic-acid) helps maintain moisture levels in the skin.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which is more affordable, Good Molecules or SK-II?

Good Molecules is more affordable, offering budget-friendly and great value [serums](https://lovi.care/skincare/nl/ingredients/serum) and moisturizers compared to SK-II.

### Between Good Molecules and SK-II, which brand is better for sensitive and gentle care according to reviewer themes?

Good Molecules does better for sensitive and gentle care compared to SK-II according to the reviewer themes on this page.

### What are the founding years and parent companies of Good Molecules and SK-II?

Good Molecules was founded in 2019 in the United States and is owned by Beautylish, Inc., while SK-II was founded in 1980 in Japan and is owned by The Procter & Gamble Company since 1991.

### Which brand performs better in terms of hydration and plumping?

SK-II performs better in terms of hydration and plumping compared to Good Molecules. Hyaluronic acid helps hydrate and improve skin quality.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Good Molecules or SK-II for oily skin?

Both Good Molecules and SK-II achieve a High routine fit level for oily skin. Reviewers indicate that Good Molecules offers great value, while SK-II delivers better brightening and hydration.

### Good Molecules or SK-II for sensitive skin?

For sensitive skin, Good Molecules has a Superior routine fit, whereas SK-II has a High routine fit on the products on this page.

### Good Molecules or SK-II for acne-prone skin?

Both Good Molecules and SK-II achieve a Superior fit for acne-prone skin on Lovi. Reviewers note that the products on this page for Good Molecules are affordable and very gentle.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Nicotinamide w, Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, D-pantothenyl alcohol · American Journal of Clinical Dermatology, 2002
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol, Ascorbic acid, Ascorbic acid powder · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · Journal of Periodontology, 2009
- [The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction](https://pubmed.ncbi.nlm.nih.gov/27475700/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016
- [Effect of fermentation time on the content of bioactive compounds with cosmetic and dermatological properties in Kombucha Yerba Mate extracts](https://pubmed.ncbi.nlm.nih.gov/34552134/) Ilex paraguariensis leaf extract · Scientific Reports, 2021
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Anti-acne vulgaris effects of chlorogenic acid by anti-inflammatory activity and lipogenesis inhibition](https://pubmed.ncbi.nlm.nih.gov/33433016/) Ilex paraguariensis leaf extract · Experimental Dermatology, 2021
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid, Ascorbic acid powder · Journal of Cosmetic Dermatology, 2020
- [A double-blind, placebo-controlled randomized trial of Serratulae quinquefoliae folium, a new source of β-arbutin, in selected skin hyperpigmentations](https://pubmed.ncbi.nlm.nih.gov/26119285/) Arbutin · Journal of Cosmetic Dermatology, 2015
- [Licochalcone A activates Nrf2 in vitro and contributes to licorice extract-induced lowered cutaneous oxidative stress in vivo](https://pubmed.ncbi.nlm.nih.gov/25381913/) Licorice root extract · Experimental Dermatology, 2015
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin, Concentrated glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine](https://pubmed.ncbi.nlm.nih.gov/17348991/) Acetyl glucosamine · Journal of Cosmetic Dermatology, 2007
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, D-pantothenyl alcohol · The Journal of Dermatological Treatment, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) D-pantothenyl alcohol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula](https://pubmed.ncbi.nlm.nih.gov/34198790/) Galactomyces ferment filtrate, Pitera essence, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Pitera ferment filtrate, Sk-ii pitera concentrate, Pitera · Journal of Clinical Medicine, 2021
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Preparation and evaluation of anti-wrinkle cream containing saffron extract and avocado oil](https://pubmed.ncbi.nlm.nih.gov/31957954/) Avocado oil · Journal of Cosmetic Dermatology, 2020
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Chemical peels for acne vulgaris: a systematic review of randomised controlled trials](https://pubmed.ncbi.nlm.nih.gov/29705755/) Mandelic acid · BMJ Open, 2018
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Challenging the safety and efficacy of topically applied chlorogenic acid, apigenin, kaempferol, and naringenin by HET-CAM, HPLC-TBARS-EVSC, and laser Doppler flowmetry](https://pubmed.ncbi.nlm.nih.gov/38831914/) Ilex paraguariensis extract · Frontiers in Chemistry, 2024
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Evaluating the Safety and Efficacy of a Topical Formulation Containing Epidermal Growth Factor, Tranexamic Acid, Vitamin C, Arbutin, Niacinamide and Other Ingredients as Hydroquinone 4% Alternatives to Improve Hyperpigmentation: A Prospective, Randomized, Controlled Split Face Study](https://pubmed.ncbi.nlm.nih.gov/33022197/) Arbutin · Journal of Cosmetic Science, 2020
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract, Camellia sinensis leaf water · Clinical, Cosmetic and Investigational Dermatology, 2019
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Reduction in the appearance of facial hyperpigmentation by topical N-undecyl-10-enoyl-L-phenylalanine and its combination with niacinamide](https://pubmed.ncbi.nlm.nih.gov/19958429/) Undecylenoyl phenylalanine · Journal of Cosmetic Dermatology, 2009
- ['All-natural' anti-wrinkle emulsion serum with Acmella oleracea extract: A design of experiments (DoE) formulation approach, rheology and in vivo skin performance/efficacy evaluation](https://pubmed.ncbi.nlm.nih.gov/34297422/) Acmella oleracea extract · International Journal of Cosmetic Science, 2021
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow bark extract · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow bark extract · Planta Medica, 2019
- [Inhibitory effects of shell of Camellia oleifera Abel extract on mushroom tyrosinase and human skin melanin](https://pubmed.ncbi.nlm.nih.gov/31033161/) Butylene glycol · Journal of Cosmetic Dermatology, 2019
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Betaine · Molecules, 2024
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [New topical tranexamic acid derivative for the improvement of hyperpigmentation and inflammation in the sun-damaged skin](https://pubmed.ncbi.nlm.nih.gov/32588531/) Cetyl tranexamate mesylate · Journal of Cosmetic Dermatology, 2021
- [Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid](https://pubmed.ncbi.nlm.nih.gov/38794349/) Betaine · Pharmaceutics, 2024
- [Fabrication of polyvinyl pyrrolidone-K90/Eudragit RL100-based dissolving microneedle patches loaded with alpha-arbutin and resveratrol for skin depigmentation](https://pubmed.ncbi.nlm.nih.gov/37183632/) Arbutin · Biomaterials Science, 2023
- [Treatment of mild to moderate acne with a fixed combination of hydroxypinacolone retinoate, retinol glycospheres and papain glycospheres](https://pubmed.ncbi.nlm.nih.gov/25876142/) Papain · Giornale Italiano Di Dermatologia E Venereologia, 2015
- [Randomized prospective study of low-dose isotretinoin alone and combination with salicylic acid and mandelic peel against acne tarda](https://pubmed.ncbi.nlm.nih.gov/35388606/) Mandelic acid · Journal of Cosmetic Dermatology, 2022
- [The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively](https://pubmed.ncbi.nlm.nih.gov/12535284/) Betaine · Skin Research and Technology, 2003
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
- [Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer](https://pubmed.ncbi.nlm.nih.gov/35456214/) Galactomyces ferment filtrate, Pitera essence, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Pitera ferment filtrate, Sk-ii pitera concentrate, Pitera · Journal of Clinical Medicine, 2022
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, D-pantothenyl alcohol · Journal of Cosmetic Dermatology, 2025
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Moisturizing Effects of Diglycerol Combined with Glycerol on Human Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/27430380/) Diglycerin · Journal of Oleo Science, 2016
- [Antioxidant and membrane-protective effects of the 3-O-ethyl ascorbic acid-cannabigerol system on UVB-irradiated human keratinocytes](https://pubmed.ncbi.nlm.nih.gov/39778604/) 3-o-ethyl ascorbic acid · Free Radical Biology & Medicine, 2025
- [Three clinical studies showing the anti-aging benefits of sodium salicylate in human skin](https://pubmed.ncbi.nlm.nih.gov/20883290/) Sodium salicylate · Journal of Cosmetic Dermatology, 2010
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Preliminary safety and in vivo efficacy of Acmella oleracea extract-loaded glycolipid emulsion serum-Effects on ocular irritation, dermal absorption, and facial skin biophysical and microrelief properties](https://pubmed.ncbi.nlm.nih.gov/39617635/) Acmella oleracea extract · International Journal of Cosmetic Science, 2025
- [Taurine and Polyphenol Complex Repaired Epidermal Keratinocyte Wounds by Regulating IL8 and TIMP2 Expression](https://pubmed.ncbi.nlm.nih.gov/39194729/) Ilex paraguariensis leaf extract · Current Issues in Molecular Biology, 2024
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Thermostable hyaluronic acid-based dissolving microneedles with high-loading capacity: design, optimization, and transdermal delivery of anti-aging ingredients](https://pubmed.ncbi.nlm.nih.gov/41628877/) 3-o-ethyl ascorbic acid · International Journal of Biological Macromolecules, 2026
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Hippophae rhamnoides oil-in-water (O/W) emulsion improves barrier function in healthy human subjects](https://pubmed.ncbi.nlm.nih.gov/25362595/) Hippophae rhamnoides oil · Pakistan Journal of Pharmaceutical Sciences, 2014
- [Development and efficacy assessments of tea seed oil makeup remover](https://pubmed.ncbi.nlm.nih.gov/27988044/) Camellia oleifera seed oil · Annales Pharmaceutiques Francaises, 2017
- [Glycerol crosslinked vitamin E loaded xanthan gum and gellan gum nanoemulgels for topical management of dry skin](https://pubmed.ncbi.nlm.nih.gov/41224059/) Xanthan gum · International Journal of Biological Macromolecules, 2025
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Pleiotropic effects of a Camellia sinensis leaf extract on in vitro and in vivo skin health characteristics](https://pubmed.ncbi.nlm.nih.gov/40391588/) Camellia sinensis leaf water · International Journal of Cosmetic Science, 2025
- [Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41319188/) Camellia oleifera seed oil · International Journal of Cosmetic Science, 2026
- [Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months-An 11-Year Longitudinal Skin Aging Rejuvenation Study](https://pubmed.ncbi.nlm.nih.gov/36769815/) Galactomyces ferment filtrate, Pitera essence, Pitera ferment filtrate galactomyces ferment filtrate, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate, Pitera · Journal of Clinical Medicine, 2023
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Centella Asiatica Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color](https://pubmed.ncbi.nlm.nih.gov/33938432/) Galactomyces ferment filtrate, Sk-ii pitera concentrate, Galactomyces ferment filtrate pitera ferment filtrate · Skinmed, 2021
- [Efficacy of anti-sebum moisturizing cream containing 2% l-carnitine and 5% epigallocatechin gallate in seborrhea: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/37194909/) Camellia sinensis leaf water · Journal of Cosmetic Dermatology, 2023
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Ascorbyl glucoside · Cureus, 2026

## The brands

- American skincare: [Good Molecules](https://lovi.care/skincare/nl/brands/good-molecules)
- Japanese skincare: [SK-II](https://lovi.care/skincare/nl/brands/sk-ii)

## More comparisons

- [SKIN1004 vs Good Molecules](https://lovi.care/skincare/nl/compare/skin1004-vs-good-molecules)
- [SKIN1004 vs SK-II](https://lovi.care/skincare/nl/compare/skin1004-vs-sk-ii)
- [Anua vs Good Molecules](https://lovi.care/skincare/nl/compare/anua-vs-good-molecules)
- [Anua vs SK-II](https://lovi.care/skincare/nl/compare/anua-vs-sk-ii)
- [Medicube vs Good Molecules](https://lovi.care/skincare/nl/compare/medicube-vs-good-molecules)
- [Medicube vs SK-II](https://lovi.care/skincare/nl/compare/medicube-vs-sk-ii)
- [The Ordinary vs Good Molecules](https://lovi.care/skincare/nl/compare/the-ordinary-vs-good-molecules)
- [The Ordinary vs SK-II](https://lovi.care/skincare/nl/compare/the-ordinary-vs-sk-ii)
- [Beauty of Joseon vs Good Molecules](https://lovi.care/skincare/nl/compare/beauty-of-joseon-vs-good-molecules)
- [Beauty of Joseon vs SK-II](https://lovi.care/skincare/nl/compare/beauty-of-joseon-vs-sk-ii)
- [COSRX vs Good Molecules](https://lovi.care/skincare/nl/compare/cosrx-vs-good-molecules)
- [COSRX vs SK-II](https://lovi.care/skincare/nl/compare/cosrx-vs-sk-ii)
- [CeraVe vs Good Molecules](https://lovi.care/skincare/nl/compare/cerave-vs-good-molecules)
- [CeraVe vs SK-II](https://lovi.care/skincare/nl/compare/cerave-vs-sk-ii)
- [La Roche-Posay vs Good Molecules](https://lovi.care/skincare/nl/compare/la-roche-posay-vs-good-molecules)
- [La Roche-Posay vs SK-II](https://lovi.care/skincare/nl/compare/la-roche-posay-vs-sk-ii)
- [Dr. Althea vs Good Molecules](https://lovi.care/skincare/nl/compare/dr-althea-vs-good-molecules)
- [Dr. Althea vs SK-II](https://lovi.care/skincare/nl/compare/dr-althea-vs-sk-ii)
- [Some By Mi vs Good Molecules](https://lovi.care/skincare/nl/compare/some-by-mi-vs-good-molecules)
- [Some By Mi vs SK-II](https://lovi.care/skincare/nl/compare/some-by-mi-vs-sk-ii)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/good-molecules-vs-sk-ii
- United Kingdom: https://lovi.care/skincare/uk/compare/good-molecules-vs-sk-ii
- Ireland: https://lovi.care/skincare/ie/compare/good-molecules-vs-sk-ii
- Germany: https://lovi.care/skincare/de/compare/good-molecules-vs-sk-ii
- France: https://lovi.care/skincare/fr/compare/good-molecules-vs-sk-ii
- Italy: https://lovi.care/skincare/it/compare/good-molecules-vs-sk-ii
- Netherlands: https://lovi.care/skincare/nl/compare/good-molecules-vs-sk-ii (this page)
- Spain: https://lovi.care/skincare/es/compare/good-molecules-vs-sk-ii
- Canada: https://lovi.care/skincare/ca/compare/good-molecules-vs-sk-ii
- Australia: https://lovi.care/skincare/au/compare/good-molecules-vs-sk-ii
- Singapore: https://lovi.care/skincare/sg/compare/good-molecules-vs-sk-ii
- Saudi Arabia: https://lovi.care/skincare/sa/compare/good-molecules-vs-sk-ii
- United Arab Emirates: https://lovi.care/skincare/ae/compare/good-molecules-vs-sk-ii