# Galderma vs Sebamed Page: https://lovi.care/skincare/nl/compare/galderma-vs-sebamed The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands. Galderma and Sebamed are established dermatological brands offering specialized solutions for distinct complexions. The Swiss enterprise focuses on targeted [serums](https://lovi.care/skincare/nl/ingredients/serum) utilizing active ingredients like [adapalene](https://lovi.care/skincare/nl/ingredients/adapalene) and [benzoyl peroxide](https://lovi.care/skincare/nl/ingredients/benzoyl-peroxide), which suit acne-prone, hyperpigmented, and mature skin effectively through formulations such as Epiduo Gel and Benzac AC. Meanwhile, the German house is known for thoughtful moisturizers and gentle cleansers that rely on scientifically balanced formulas and a skin-neutral pH to support reactive and problematic barriers, highlighted by staples like the Facial Cleanser and Clear Face Care Gel. While both care for blemish-prone areas, they differ fundamentally as the former addresses specific dermatological concerns with potent gels, whereas the latter prioritizes daily physiological balance. Galderma is a Swiss skincare brand founded in 1981 and owned by Galderma Group AG. [en.wikipedia.org](https://en.wikipedia.org/wiki/Galderma) Sebamed is a German skincare brand founded in 1967 and owned by Sebapharma GmbH & Co. KG. [sebamed.ae](https://sebamed.ae/en/article/2/Sebapharma) [sebamed.com](https://sebamed.com/en/info/company/about-us/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Sebamed) [de.wikipedia.org](https://de.wikipedia.org/wiki/Sebamed) This page compares some of the most popular Galderma and Sebamed products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgdd421184bc). ### Popular Galderma vs Sebamed products #### Galderma - [Epiduo Gel](https://lovi.care/skincare/nl/p/galderma/epiduo-gel/for/acne-prone-skin) — High fit - [Benzac AC 5](https://lovi.care/skincare/nl/p/galderma/benzac-ac-5/for/oily-acne-prone-skin) — High fit - [Benzac AC Mild Strength 2.5% Acne Gel](https://lovi.care/skincare/nl/p/galderma/benzac-ac-mild-strength-2-5-acne-gel/for/oily-acne-prone-skin) — High fit #### Sebamed - [Clear Face Care Gel](https://lovi.care/skincare/nl/p/sebamed/clear-face-care-gel/for/oily-acne-prone-skin) — High fit — [€14.50 at Amazon](https://www.amazon.nl/dp/B00NGK6AM8?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1) - [Facial Cleanser](https://lovi.care/skincare/nl/p/sebamed/facial-cleanser/for/combination-skin) — High fit ## Questions and answers ### Galderma or Sebamed: which is better? Galderma has a High Lovi fit for oily acne-prone skin with its acne-clearing [serums](https://lovi.care/skincare/nl/ingredients/serum) on this page, but it may cause severe dryness and peeling. Sebamed also has a High Lovi fit for oily acne-prone skin using its gentle facial cleanser. [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/) [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/) ### What is the difference between Galderma and Sebamed? Galderma features effective acne-clearing serums that have a High Lovi fit for oily acne-prone skin, whereas Sebamed offers products like a cleanser with a High Lovi fit for sensitive and oily acne-prone skin. Reviewers often note that Galderma products can cause severe dryness and irritation. [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/) ### Which is more affordable, Galderma or Sebamed? The provided page facts do not mention the prices of Galderma and Sebamed products, so it is not possible to determine which brand is more affordable. ### Which causes fewer breakouts, Galderma or Sebamed? Galderma is known for effective acne-clearing serums on this page, whereas Sebamed offers a facial cleanser and a care gel that fit oily acne-prone skin with High and Average levels respectively. [The Cochrane Database of Systematic Reviews, 2020](https://pubmed.ncbi.nlm.nih.gov/32175593/) [American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/) ### Which brand was founded earlier, Galderma or Sebamed? Sebamed was founded earlier in 1967 in Germany, whereas Galderma was founded later in 1981 in Switzerland. ### Do any of the products from Galderma or Sebamed contain fragrance? None of the products on this page from Galderma or Sebamed contain fragrance. Every product listed for both brands features no fragrance in its ingredients. ### How does the Lovi fit level for oily acne-prone skin compare between Galderma's Epiduo Gel and Sebamed's Clear Face Care Gel? Galderma's Epiduo Gel has a High Lovi fit level for oily acne-prone skin, while Sebamed's Clear Face Care Gel has an Average fit level for that skin type. ## Research behind their key ingredients - [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022 - [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002 - [The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction](https://pubmed.ncbi.nlm.nih.gov/27475700/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016 - [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018 - [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide, Benzoyl peroxide 25mg g · The Cochrane Database of Systematic Reviews, 2020 - [Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison](https://pubmed.ncbi.nlm.nih.gov/29549588/) Adapalene · American Journal of Clinical Dermatology, 2018 - [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of Shoulder and Elbow Surgery, 2021 - [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017 - [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide, Benzoyl peroxide 25mg g · American Journal of Clinical Dermatology, 2022 - [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017 - [A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/34251536/) Adapalene · Archives of Dermatological Research, 2022 - [Development of Multifunctional Cosmetic Cream Using Bioactive Materials from Streptomyces sp. T65 with Synthesized Mesoporous Silica Particles SBA-15](https://pubmed.ncbi.nlm.nih.gov/32224894/) Silicon dioxide · Antioxidants, 2020 - [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020 - [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel bark extract · Phytochemistry, 2001 - [Formulating octyl methoxycinnamate in hybrid lipid-silica nanoparticles: An innovative approach for UV skin protection](https://pubmed.ncbi.nlm.nih.gov/32395645/) Silicon dioxide · Heliyon, 2020 - [Clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel for moderate-to-severe acne: Efficacy and safety results from two randomized phase 3 trials](https://pubmed.ncbi.nlm.nih.gov/37656094/) Adapalene · Journal of the American Academy of Dermatology, 2023 - [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide, Benzoyl peroxide 25mg g · Journal of the American Academy of Dermatology, 2023 - [Semi-Solid Dosage Forms Containing Pranoprofen-Loaded NLC as Topical Therapy for Local Inflammation: In Vitro, Ex Vivo and In Vivo Evaluation](https://pubmed.ncbi.nlm.nih.gov/37367119/) Carbomer 940 · Gels, 2023 - [Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol](https://pubmed.ncbi.nlm.nih.gov/23752031/) Sorbitol · Journal of Cosmetic Science, 2013 - [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025 ## The brands - Swiss skincare: [Galderma](https://lovi.care/skincare/nl/brands/galderma) - German skincare: [Sebamed](https://lovi.care/skincare/nl/brands/sebamed) ## More comparisons - [SKIN1004 vs Galderma](https://lovi.care/skincare/nl/compare/skin1004-vs-galderma) - [SKIN1004 vs Sebamed](https://lovi.care/skincare/nl/compare/skin1004-vs-sebamed) - [Anua vs Galderma](https://lovi.care/skincare/nl/compare/anua-vs-galderma) - [Anua vs Sebamed](https://lovi.care/skincare/nl/compare/anua-vs-sebamed) - [Medicube vs Galderma](https://lovi.care/skincare/nl/compare/medicube-vs-galderma) - [Medicube vs Sebamed](https://lovi.care/skincare/nl/compare/medicube-vs-sebamed) - [The Ordinary vs Galderma](https://lovi.care/skincare/nl/compare/the-ordinary-vs-galderma) - [The Ordinary vs Sebamed](https://lovi.care/skincare/nl/compare/the-ordinary-vs-sebamed) - [Beauty of Joseon vs Galderma](https://lovi.care/skincare/nl/compare/beauty-of-joseon-vs-galderma) - [Beauty of Joseon vs Sebamed](https://lovi.care/skincare/nl/compare/beauty-of-joseon-vs-sebamed) - [COSRX vs Galderma](https://lovi.care/skincare/nl/compare/cosrx-vs-galderma) - [COSRX vs Sebamed](https://lovi.care/skincare/nl/compare/cosrx-vs-sebamed) - [CeraVe vs Galderma](https://lovi.care/skincare/nl/compare/cerave-vs-galderma) - [CeraVe vs Sebamed](https://lovi.care/skincare/nl/compare/cerave-vs-sebamed) - [La Roche-Posay vs Galderma](https://lovi.care/skincare/nl/compare/la-roche-posay-vs-galderma) - [La Roche-Posay vs Sebamed](https://lovi.care/skincare/nl/compare/la-roche-posay-vs-sebamed) - [Dr. Althea vs Galderma](https://lovi.care/skincare/nl/compare/dr-althea-vs-galderma) - [Dr. Althea vs Sebamed](https://lovi.care/skincare/nl/compare/dr-althea-vs-sebamed) - [Some By Mi vs Galderma](https://lovi.care/skincare/nl/compare/some-by-mi-vs-galderma) - [Some By Mi vs Sebamed](https://lovi.care/skincare/nl/compare/some-by-mi-vs-sebamed) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/compare/galderma-vs-sebamed - United Kingdom: https://lovi.care/skincare/uk/compare/galderma-vs-sebamed - Ireland: https://lovi.care/skincare/ie/compare/galderma-vs-sebamed - Germany: https://lovi.care/skincare/de/compare/galderma-vs-sebamed - France: https://lovi.care/skincare/fr/compare/galderma-vs-sebamed - Italy: https://lovi.care/skincare/it/compare/galderma-vs-sebamed - Netherlands: https://lovi.care/skincare/nl/compare/galderma-vs-sebamed (this page) - Spain: https://lovi.care/skincare/es/compare/galderma-vs-sebamed - Canada: https://lovi.care/skincare/ca/compare/galderma-vs-sebamed - Australia: https://lovi.care/skincare/au/compare/galderma-vs-sebamed - Singapore: https://lovi.care/skincare/sg/compare/galderma-vs-sebamed - Saudi Arabia: https://lovi.care/skincare/sa/compare/galderma-vs-sebamed - United Arab Emirates: https://lovi.care/skincare/ae/compare/galderma-vs-sebamed