# Azclear vs Mesoestetic Page: https://lovi.care/skincare/nl/compare/azclear-vs-mesoestetic The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands. Azclear and Mesoestetic are refined skincare lines offering thoughtfully formulated treatments for diverse complexions. Azclear is deeply appreciated for its soothing [serums](https://lovi.care/skincare/nl/ingredients/serum), while the Spanish brand Mesoestetic is beloved for its targeted serums. Both feature meticulously crafted formulas that suit sensitive and acne-prone skin best, though the former is known for its Medicated Lotion and the latter for its Cosmelan 2. Ultimately, the brands differ in their origins and specific product offerings, with each delivering balanced nourishment to support long-term skin health. Mesoestetic is a Spanish skincare brand founded in 1984 and owned by Mesoestetic Pharma Group, S.L.. [mesoestetic.com](https://www.mesoestetic.com/about-us) [tracxn.com](https://tracxn.com/d/companies/mesoestetic/__1eAnF7uALQzHII_So8HqZbHfSUJuilusj9hTisrG0tk) This page compares some of the most popular Azclear and Mesoestetic products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg58166efb5d). ### Popular Azclear vs Mesoestetic products #### Azclear - [Medicated Lotion](https://lovi.care/skincare/nl/p/azclear/medicated-lotion/for/oily-acne-prone-skin) — High fit #### Mesoestetic - [Cosmelan 2](https://lovi.care/skincare/nl/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit ### Azclear vs Mesoestetic [serums](https://lovi.care/skincare/nl/ingredients/serum) and treatments #### Azclear - [Medicated Lotion](https://lovi.care/skincare/nl/p/azclear/medicated-lotion/for/oily-acne-prone-skin) — High fit #### Mesoestetic - [Cosmelan 2](https://lovi.care/skincare/nl/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit ## Questions and answers ### Azclear or Mesoestetic: which is better? Azclear has a High Lovi fit for oily acne-prone skin with its Medicated Lotion, whereas Mesoestetic achieves an Average fit for that skin type with Cosmelan 2. [Azelaic acid](https://lovi.care/skincare/nl/ingredients/azelaic-acid) helps manage acne vulgaris. [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/) ### What is the difference between Azclear and Mesoestetic? Azclear Medicated Lotion has a High fit for oily acne-prone skin, whereas Mesoestetic Cosmelan 2 has an Average fit for that skin type. Both brands offer products on this page that list no fragrance in their ingredients. ### Which is more affordable, Azclear or Mesoestetic? I am sorry, but the provided page facts and studies do not contain pricing information to determine whether Azclear or Mesoestetic is more affordable. ### Which causes fewer breakouts, Azclear or Mesoestetic? For oily acne-prone skin, Azclear Medicated Lotion has a High Lovi fit, while Mesoestetic Cosmelan 2 has an Average fit, so Azclear helps with breakouts more. Both brands list no fragrance in the products on this page. [Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/) ### When were Azclear and Mesoestetic founded and where is Mesoestetic based? Mesoestetic was founded in 1984 in Spain, while the founding year for Azclear is not available. ### How does the Lovi fit level of Azclear Medicated Lotion compare to Mesoestetic Cosmelan 2 for oily acne-prone skin? Azclear Medicated Lotion has a High Lovi fit level for oily acne-prone skin, whereas Mesoestetic Cosmelan 2 has an Average Lovi fit level for the same skin type. ### Do any products from Azclear or Mesoestetic contain fragrance? Every product on this page from Azclear and Mesoestetic lists no fragrance in its ingredients. ## Research behind their key ingredients - [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002 - [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018 - [Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study](https://pubmed.ncbi.nlm.nih.gov/34211271/) Retinyl palmitate · International Journal of Nanomedicine, 2021 - [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021 - [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017 - [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020 - [Inhibition of TRPV1 prevented skin irritancy induced by phenoxyethanol. A preliminary in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/27168163/) Phenoxyethanol · International Journal of Cosmetic Science, 2017 - [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024 - [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024 - [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023 - [The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study](https://pubmed.ncbi.nlm.nih.gov/36729399/) Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023 ## The brands - Skincare: [Azclear](https://lovi.care/skincare/nl/brands/azclear) - Spanish skincare: [Mesoestetic](https://lovi.care/skincare/nl/brands/mesoestetic) ## More comparisons - [SKIN1004 vs Azclear](https://lovi.care/skincare/nl/compare/skin1004-vs-azclear) - [SKIN1004 vs Mesoestetic](https://lovi.care/skincare/nl/compare/skin1004-vs-mesoestetic) - [Anua vs Azclear](https://lovi.care/skincare/nl/compare/anua-vs-azclear) - [Anua vs Mesoestetic](https://lovi.care/skincare/nl/compare/anua-vs-mesoestetic) - [Medicube vs Azclear](https://lovi.care/skincare/nl/compare/medicube-vs-azclear) - [Medicube vs Mesoestetic](https://lovi.care/skincare/nl/compare/medicube-vs-mesoestetic) - [The Ordinary vs Azclear](https://lovi.care/skincare/nl/compare/the-ordinary-vs-azclear) - [The Ordinary vs Mesoestetic](https://lovi.care/skincare/nl/compare/the-ordinary-vs-mesoestetic) - [Beauty of Joseon vs Azclear](https://lovi.care/skincare/nl/compare/beauty-of-joseon-vs-azclear) - [Beauty of Joseon vs Mesoestetic](https://lovi.care/skincare/nl/compare/beauty-of-joseon-vs-mesoestetic) - [COSRX vs Azclear](https://lovi.care/skincare/nl/compare/cosrx-vs-azclear) - [COSRX vs Mesoestetic](https://lovi.care/skincare/nl/compare/cosrx-vs-mesoestetic) - [CeraVe vs Azclear](https://lovi.care/skincare/nl/compare/cerave-vs-azclear) - [CeraVe vs Mesoestetic](https://lovi.care/skincare/nl/compare/cerave-vs-mesoestetic) - [La Roche-Posay vs Azclear](https://lovi.care/skincare/nl/compare/la-roche-posay-vs-azclear) - [La Roche-Posay vs Mesoestetic](https://lovi.care/skincare/nl/compare/la-roche-posay-vs-mesoestetic) - [Dr. Althea vs Azclear](https://lovi.care/skincare/nl/compare/dr-althea-vs-azclear) - [Dr. Althea vs Mesoestetic](https://lovi.care/skincare/nl/compare/dr-althea-vs-mesoestetic) - [Some By Mi vs Azclear](https://lovi.care/skincare/nl/compare/some-by-mi-vs-azclear) - [Some By Mi vs Mesoestetic](https://lovi.care/skincare/nl/compare/some-by-mi-vs-mesoestetic) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/compare/azclear-vs-mesoestetic - United Kingdom: https://lovi.care/skincare/uk/compare/azclear-vs-mesoestetic - Ireland: https://lovi.care/skincare/ie/compare/azclear-vs-mesoestetic - Germany: https://lovi.care/skincare/de/compare/azclear-vs-mesoestetic - France: https://lovi.care/skincare/fr/compare/azclear-vs-mesoestetic - Italy: https://lovi.care/skincare/it/compare/azclear-vs-mesoestetic - Netherlands: https://lovi.care/skincare/nl/compare/azclear-vs-mesoestetic (this page) - Spain: https://lovi.care/skincare/es/compare/azclear-vs-mesoestetic - Canada: https://lovi.care/skincare/ca/compare/azclear-vs-mesoestetic - Australia: https://lovi.care/skincare/au/compare/azclear-vs-mesoestetic - Singapore: https://lovi.care/skincare/sg/compare/azclear-vs-mesoestetic - Saudi Arabia: https://lovi.care/skincare/sa/compare/azclear-vs-mesoestetic - United Arab Emirates: https://lovi.care/skincare/ae/compare/azclear-vs-mesoestetic