# Azclear vs ISDIN Isdinceutics

Page: https://lovi.care/skincare/nl/compare/azclear-vs-isdin-isdinceutics

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Azclear and ISDIN Isdinceutics are distinct skincare options that offer thoughtful formulations to gently nurture and balance the complexion. Azclear is deeply appreciated for its soothing [serums](https://lovi.care/skincare/nl/ingredients/serum) and carefully balanced formulas, specifically featuring the Medicated Lotion as a standout product for acne-prone skin, making the brand well-suited for sensitive, acne-prone, and reactive skin types. Conversely, ISDIN Isdinceutics is revered for its targeted eye products and advanced formulas, featuring the K-Ox Eyes as a standout product that offers noticeable relief for acne-prone skin while regular use supports a visibly rested, smooth, and balanced complexion, suiting mature, dry, and sensitive skin best due to their gentle yet effective compositions. Ultimately, both differ primarily in their core product types and targeted skin concerns, allowing individuals to select the option that best aligns with their unique needs.

ISDIN Isdinceutics is a Spanish skincare brand founded in 1975 and owned by Puig since 2027.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/)

This page compares some of the most popular Azclear and ISDIN Isdinceutics products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgb8c6735ee4).

### Popular Azclear vs ISDIN Isdinceutics products

#### ISDIN Isdinceutics

- [K-Ox Eyes](https://lovi.care/skincare/nl/p/isdin-isdinceutics/k-ox-eyes/for/dry-skin) — High fit

#### Azclear

- [Medicated Lotion](https://lovi.care/skincare/nl/p/azclear/medicated-lotion/for/oily-acne-prone-skin) — High fit

## Questions and answers

### Azclear or ISDIN Isdinceutics: which is better?

Azclear Medicated Lotion achieves a High fit for oily acne-prone skin, while ISDIN Isdinceutics K-Ox Eyes achieves a High fit for dry, sensitive, and mature skin. Furthermore, every product on this page for Azclear lists no fragrance, whereas the ISDIN Isdinceutics product contains fragrance.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### What is the difference between Azclear and ISDIN Isdinceutics?

Azclear has a High Lovi fit for oily acne-prone skin with its fragrance-free Medicated Lotion, whereas ISDIN Isdinceutics achieves a High Lovi fit for dry, sensitive, and mature skin with its K-Ox Eyes product, which does contain fragrance.

### Which is more affordable, Azclear or ISDIN Isdinceutics?

This page does not provide pricing information to compare the affordability of Azclear and ISDIN Isdinceutics.

### Which causes fewer breakouts, Azclear or ISDIN Isdinceutics?

Azclear Medicated Lotion has a High fit for oily acne-prone skin and an Average fit for acne-prone skin, whereas ISDIN Isdinceutics K-Ox Eyes has an Average fit for acne-prone skin. [Azelaic acid](https://lovi.care/skincare/nl/ingredients/azelaic-acid) helps reduce acne.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

### How do Azclear and ISDIN Isdinceutics compare in terms of fragrance-free product options?

Azclear has a fragrance-free option because every product on this page lists no fragrance in its ingredients, whereas ISDIN Isdinceutics does not have fragrance-free options as its products contain fragrance.

### Which brand has been around longer, Azclear or ISDIN Isdinceutics?

ISDIN Isdinceutics has been around longer, having been founded in Spain in 1975, while Azclear was founded in 2010.

### Which brand offers a better fit for oily acne-prone skin, Azclear or ISDIN Isdinceutics?

Azclear offers a better fit for oily acne-prone skin, where Lovi gives it a High fit level compared to the average fit from ISDIN Isdinceutics. Additionally, every product on this page from Azclear lists no fragrance in its ingredients.

[Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33923739/)

## Research behind their key ingredients

- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Chrysin protects epidermal keratinocytes from UVA- and UVB-induced damage](https://pubmed.ncbi.nlm.nih.gov/21699266/) Chrysin · Journal of Agricultural and Food Chemistry, 2011
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Inhibition of TRPV1 prevented skin irritancy induced by phenoxyethanol. A preliminary in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/27168163/) Phenoxyethanol · International Journal of Cosmetic Science, 2017
- [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study](https://pubmed.ncbi.nlm.nih.gov/36729399/) Azelaic acid · Journal of the European Academy of Dermatology and Venereology, 2023
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Chitosan derivative nanocarrier: safety evaluation,antibacterial property and ascorbyl palmitate encapsulation](https://pubmed.ncbi.nlm.nih.gov/19566395/) Ascorbyl palmitate · Journal of Microencapsulation, 2010
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026

## The brands

- Skincare: [Azclear](https://lovi.care/skincare/nl/brands/azclear)
- Spanish skincare: [ISDIN Isdinceutics](https://lovi.care/skincare/nl/brands/isdin-isdinceutics)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/azclear-vs-isdin-isdinceutics
- United Kingdom: https://lovi.care/skincare/uk/compare/azclear-vs-isdin-isdinceutics
- Ireland: https://lovi.care/skincare/ie/compare/azclear-vs-isdin-isdinceutics
- Germany: https://lovi.care/skincare/de/compare/azclear-vs-isdin-isdinceutics
- France: https://lovi.care/skincare/fr/compare/azclear-vs-isdin-isdinceutics
- Italy: https://lovi.care/skincare/it/compare/azclear-vs-isdin-isdinceutics
- Netherlands: https://lovi.care/skincare/nl/compare/azclear-vs-isdin-isdinceutics (this page)
- Spain: https://lovi.care/skincare/es/compare/azclear-vs-isdin-isdinceutics
- Canada: https://lovi.care/skincare/ca/compare/azclear-vs-isdin-isdinceutics
- Australia: https://lovi.care/skincare/au/compare/azclear-vs-isdin-isdinceutics
- Singapore: https://lovi.care/skincare/sg/compare/azclear-vs-isdin-isdinceutics
- Saudi Arabia: https://lovi.care/skincare/sa/compare/azclear-vs-isdin-isdinceutics
- United Arab Emirates: https://lovi.care/skincare/ae/compare/azclear-vs-isdin-isdinceutics
