# Avène vs MAC

Page: https://lovi.care/skincare/nl/compare/avene-vs-mac

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Avène and MAC are distinct beauty houses, with the former being a French skincare brand founded in 1990 and owned by Fondation Pierre Fabre, while the latter is a Canadian skincare brand founded in 1984 and owned by The Estée Lauder Companies Inc. since 1994. The French label is universally loved for its versatile moisturizers, reliable sunscreens, targeted [serums](https://lovi.care/skincare/nl/ingredients/serum), and gentle cleansers, all formulated with nourishing [glycerin](https://lovi.care/skincare/nl/ingredients/glycerin), whereas the Canadian label is beloved for its thoughtful approach to daily skincare, offering reliable moisturizers and makeup removers crafted from carefully balanced formulas. Products from the former suit acne-prone skin and oily acne-prone skin best, offering profound relief without heaviness, while offerings from the latter suit balanced skin best, supported by gentle and effective ingredients. They differ because the former relies on glycerin to improve skin hydration and restore barrier function, whereas the latter provides a calm and measured foundation for daily maintenance.

Avène is a French skincare brand founded in 1990 and owned by Fondation Pierre Fabre.

[pierre-fabre.com](https://www.pierre-fabre.com/en/our-company/governance) [avene.co.uk](https://www.avene.co.uk/a/water-that-makes-all-the-difference-thermal-spring-water) [aveneusa.com](https://www.aveneusa.com/history)

MAC is a Canadian skincare brand founded in 1984 and owned by The Estée Lauder Companies Inc. since 1994.

[elcompanies.com](https://www.elcompanies.com/en-gb/our-brands/mac) [en.wikipedia.org](https://en.wikipedia.org/wiki/Est%C3%A9e_Lauder_Companies)

This page compares some of the most popular Avène and MAC products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg7159c624d5).

### Popular Avène vs MAC products

#### Avène

- [Cicalfate+ Restorative Protective Cream](https://lovi.care/skincare/nl/p/avene/cicalfate-restorative-protective-cream/for/dry-skin) — High fit — [€9.15 at Amazon](https://www.amazon.nl/dp/B07XG1PLJF?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Cleanance](https://lovi.care/skincare/nl/p/avene/cleanance/for/oily-skin) — Superior fit — [€17.55 at Amazon](https://www.amazon.nl/dp/B01MQWXZNV?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Cleanance Cleansing Gel](https://lovi.care/skincare/nl/p/avene/cleanance-cleansing-gel/for/oily-acne-prone-skin) — High fit — [€17.55 at Amazon](https://www.amazon.nl/dp/B01MQWXZNV?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [Hydrance+](https://lovi.care/skincare/nl/p/avene/hydrance/for/dry-sensitive-skin) — Average fit
- [Tolerance Control Soothing Skin Recovery Balm](https://lovi.care/skincare/nl/p/avene/tolerance-control-soothing-skin-recovery-balm/for/dry-skin) — Superior fit — [€23.86 at Amazon](https://www.amazon.nl/dp/B08XYVMRP7?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)
- [RetrinAL EYES](https://lovi.care/skincare/nl/p/avene/retrinal-eyes/for/dry-skin) — High fit
- [Cold Cream](https://lovi.care/skincare/nl/p/avene/cold-cream/for/dry-sensitive-skin) — High fit
- [Vitamin Activ Cg Radiance Concentrated Serum](https://lovi.care/skincare/nl/p/avene/vitamin-activ-cg-radiance-concentrated-serum/for/mature-skin) — High fit — [€26.70 at Amazon](https://www.amazon.nl/dp/B0CNKJTV1X?tag=lovi-care-web-product085-21&linkCode=osi&th=1&psc=1)

#### MAC

- [Hyper Real Serumizer](https://lovi.care/skincare/nl/p/mac/hyper-real-serumizer/for/dry-sensitive-skin) — High fit — [€51.75 at Lookfantastic](https://www.lookfantastic.nl/p/mac-hyper-real-serumizertm-skin-balancing-hydration-serum-30ml/14194687/)
- [Mineralize Timecheck Lotion](https://lovi.care/skincare/nl/p/mac/mineralize-timecheck-lotion/for/dry-skin) — High fit
- [Hyper Real Fresh Canvas Cleansing Oil](https://lovi.care/skincare/nl/p/mac/hyper-real-fresh-canvas-cleansing-oil/for/dry-sensitive-skin) — High fit

## People Say

Avène

MAC

- Excellent makeup base and primer Not noted Mostly Mentioned “foundation glides on — MAC Hyper Real Serumizer” “Sits beautifully under makeup — MAC Mineralize Timecheck Lotion”
- Soothes and calms skin Mostly Mentioned Not noted “Calmed my angry red skin overnight — Avène Cicalfate+ Restorative Protective Cream” “Nothing has ever worked to soothe or heal my skin like these before. — Avène Tolerance Control Soothing Skin Recovery Balm” “Perfect cleanser for sensitive skin. — Avène Milk Cleanser”
- Lightweight hydration and radiant glow Not noted Mostly Mentioned “absorbs quickly — MAC Hyper Real Serumizer” “lit-from-within look — MAC Hyper Real Serumizer” “Absorbs in a snap — MAC Mineralize Timecheck Lotion”
- Softens skin texture and blurs pores Not noted Often Mentioned “Reduces appearance of pores — MAC Mineralize Timecheck Lotion” “petal-soft skin — MAC Hyper Real Serumizer”
- Gentle and non-stripping cleansing Sometimes Noted Often Mentioned “Emulsifies beautifully and rinses off without a greasy film. — MAC Hyper Real Fresh Canvas Cleansing Oil” “Leaves skin feeling soft and supple, never tight. — MAC Hyper Real Fresh Canvas Cleansing Oil” “Doesn't sting my eyes or blur my vision. — MAC Hyper Real Fresh Canvas Cleansing Oil” “leaves face clean but not dry — Avène Cleanance”
- Effective makeup removal Rarely Noted Often Mentioned “Removes waterproof mascara completely without needing a separate remover. — MAC Hyper Real Fresh Canvas Cleansing Oil” “Remove a all of the makeup with ease. — Avène Milk Cleanser”
- Price point and value Sometimes Noted Mostly Mentioned “Its a bit pricey but so worth it!! — Avène Tolerance Control Soothing Skin Recovery Balm” “a bit pricey — Avène Cleanance” “Tiny tube for the money — Avène Cold Cream” “too expensive — MAC Hyper Real Serumizer”
- Strong fragrance and scent Sometimes Noted Often Mentioned “The fragrance is very present. — Avène Milk Cleanser” “smell is too strong — Avène Cleanance” “scent is overpowering — MAC Hyper Real Serumizer” “Has a scent that might irritate very sensitive noses. — MAC Hyper Real Fresh Canvas Cleansing Oil”
- Causes breakouts and acne Sometimes Noted Sometimes Noted “Woke up with tiny whiteheads all over — Avène Cicalfate+ Restorative Protective Cream” “Caused small bumps/texture — Avène Soothing Radiance Mask” “caused acne — MAC Hyper Real Serumizer” “Breaks me out, I got pimples from this. — MAC Hyper Real Fresh Canvas Cleansing Oil”
- Not hydrating enough or ineffective Rarely Noted Sometimes Noted “no difference — Avène Antirougeurs Fort Relief Concentrate” “Not hydrating enough and my skin feels so dry even right after applying the cream. — Avène Tolerance Control Soothing Skin Recovery Balm” “no difference after month — Avène Vitamin Activ Cg Radiance Concentrated Serum” “Don't expect miracles — MAC Mineralize Timecheck Lotion”

## Questions and answers

### Avène or MAC: which is better?

When comparing the products on this page, Avène may be a better choice for soothing irritated skin and managing oil control, whereas MAC is often preferred for its lightweight moisturizers and excellent makeup bases. Lovi finds that Avène fits acne-prone skin best, while both brands generally feature options that help hydrate and soften skin.

### What is the difference between Avène and MAC?

Avène is better for soothing and calming irritated skin, while MAC does better with makeup bases, primers, and gentle, non-stripping cleansing. [Glycerin](https://lovi.care/skincare/nl/ingredients/glycerin) helps provide moisture in the products on this page.

### Avène or MAC: which moisturizer is better?

For moisturizers, Lovi rates Avène Tolerance Control Soothing Skin Recovery Balm as having a Superior fit for dry skin, whereas MAC Mineralize Timecheck Lotion has a High fit and Hyper Real Serumizer has an Average fit. Avène also helps soothe and calm skin better according to reviews.

### Which is more affordable, Avène or MAC?

Avène is more affordable than MAC, as Avène is noted for better price point and value. The products on this page for both brands feature glycerin, which helps hydrate the skin.

### Which causes fewer breakouts, Avène or MAC?

According to the review themes on this page, Avène and MAC perform equally when it comes to causing breakouts and acne.

### How do the founding years and parent companies of Avène and MAC compare?

Avène was founded in France in 1990 and is owned by Fondation Pierre Fabre, whereas MAC was founded in Canada in 1984 and has been owned by The Estée Lauder Companies Inc. since 1994.

### Which brand has more fragrance-free options among the products listed?

Avène has more fragrance-free options on this page, with 7 of its 15 products listing no fragrance, whereas none of the products from MAC are fragrance-free.

### What are the specific reviewer opinions regarding the cleansers and sunscreens of Avène?

Reviewers note that the products on this page by Avène feature gentle and non-stripping sunscreens and a gentle deep clean from their cleansers.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate · Dermatologic Therapy, 2022
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo](https://pubmed.ncbi.nlm.nih.gov/12823436/) Ascorbic acid activ cg · Experimental Dermatology, 2003
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol, Bakuchiol · The British Journal of Dermatology, 2019
- [Effect of Camellia japonica oil on human type I procollagen production and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/17386986/) Camellia japonica seed oil · Journal of Ethnopharmacology, 2007
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Efficacy and tolerability assessment of a topical formulation containing copper sulfate and hypericum perforatum on patients with herpes skin lesions: a comparative, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/22270204/) Copper sulfate · Journal of Drugs in Dermatology, 2012
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Self-Assembled Cubic Liquid Crystalline Nanoparticles for Transdermal Delivery of Paeonol](https://pubmed.ncbi.nlm.nih.gov/26517086/) Paeonia albiflora flower extract · Medical Science Monitor, 2015
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Paeonia albiflora flower extract · Molecules, 2023
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [An oil-soluble extract of Rubus idaeus cells enhances hydration and water homeostasis in skin cells](https://pubmed.ncbi.nlm.nih.gov/25940647/) Rubus idaeus fruit extract raspberry fruit extract · International Journal of Cosmetic Science, 2015
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Clay jojoba oil facial mask for lesioned skin and mild acne--results of a prospective, observational pilot study](https://pubmed.ncbi.nlm.nih.gov/22585103/) Jojoba seed oil · Forschende Komplementarmedizin, 2012
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study](https://pubmed.ncbi.nlm.nih.gov/36698447/) Zinc gluconate · Clinical, Cosmetic and Investigational Dermatology, 2023
- [A new dermocosmetic containing retinaldehyde, delta-tocopherol glucoside and glycylglycine oleamide for managing naturally aged skin: results from in vitro to clinical studies](https://pubmed.ncbi.nlm.nih.gov/28203099/) Tocopheryl glucoside · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Efficacy and safety of non-thermal nitrogen plasma versus long-pulsed Nd:YAG laser for hand rejuvenation](https://pubmed.ncbi.nlm.nih.gov/33420853/) Nitrogen · Lasers in Medical Science, 2022
- [Subclinical cutaneous inflammation remained after permeability barrier disruption enhances UV sensitivity by altering ER stress responses and topical pseudoceramide prevents them](https://pubmed.ncbi.nlm.nih.gov/28631090/) Ceramide ng · Archives of Dermatological Research, 2017
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Comparative benefit of two thermal spring waters after photodynamic therapy procedure](https://pubmed.ncbi.nlm.nih.gov/17348993/) Avène thermal spring water, Avene thermal spring water avene aqua · Journal of Cosmetic Dermatology, 2007
- [Partially purified paeoniflorin exerts protective effects on UV-induced DNA damage and reduces facial wrinkles in human skin](https://pubmed.ncbi.nlm.nih.gov/16676123/) Paeonia albiflora flower extract · Journal of Cosmetic Science, 2006
- [Wax-oil lubricants to reduce the shear between skin and PPE](https://pubmed.ncbi.nlm.nih.gov/34078980/) Paraffinum liquidum mineral oil · Scientific Reports, 2021
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Effects of Investigational Moisturizers on the Skin Barrier and Microbiome following Exposure to Environmental Aggressors: A Randomized Clinical Trial and Ex Vivo Analysis](https://pubmed.ncbi.nlm.nih.gov/37763018/) Yeast extract · Journal of Clinical Medicine, 2023
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Specific protection of sensitive skin against environmental stress by maintenance and improvement of barrier function](https://pubmed.ncbi.nlm.nih.gov/35315151/) Aquaphilus dolomiae extract filtrate · Journal of the European Academy of Dermatology and Venereology, 2022
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Butyl methoxydibenzoylmethane · European Journal of Pharmaceutical Sciences, 2023
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Sustained effect of two antioxidants (oxothiazolidine and δ-tocopheryl glucoside) for immediate and long-term sun protection in a sunscreen emulsion based on their different penetrating properties](https://pubmed.ncbi.nlm.nih.gov/33848378/) Tocopheryl glucoside · International Journal of Cosmetic Science, 2021
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Citric acid · Journal of Drugs in Dermatology, 2013
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Clinical evaluation of anaesthetic-like effect of two dermocosmetic formulations containing Aquaphilus dolomiae extract-G3 in subjects with sensitive facial skin](https://pubmed.ncbi.nlm.nih.gov/35315150/) Aquaphilus dolomiae extract filtrate · Journal of the European Academy of Dermatology and Venereology, 2022
- [The Real-World Effectiveness and Tolerability of a Soothing Cream Containing the Postbiotic Aquaphilus dolomiae Extract-G2 for Skin Healing](https://pubmed.ncbi.nlm.nih.gov/38451421/) Aquaphilus dolomiae extract filtrate · Dermatology and Therapy, 2024
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Protective properties of Avène Thermal Spring Water on biomechanical, ultrastructural and clinical parameters of human skin](https://pubmed.ncbi.nlm.nih.gov/32870553/) Thermal spring water, Aqua dolomiae extract · Journal of the European Academy of Dermatology and Venereology, 2020
- [Effects of Malaysian thermal spring water as adjunct therapy for mild to moderate acne vulgaris - a prospective, randomised, controlled, split face study](https://pubmed.ncbi.nlm.nih.gov/38553920/) Avène thermal spring water, Avene thermal spring water avene aqua, Thermal spring water · The Medical Journal of Malaysia, 2024
- [Rapid and Visible Efficacy of a Dermocosmetic in Acne Patients With Fair Skin Phototypes: Results of a Randomized Split-Face Study](https://pubmed.ncbi.nlm.nih.gov/41487026/) Zinc gluconate · Journal of Cosmetic Dermatology, 2026
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [A cleanser formulated with Tris (hydroxymethyl) aminomethane and l-arginine significantly improves facial acne in male Thai subjects](https://pubmed.ncbi.nlm.nih.gov/31347768/) Arginine · Journal of Cosmetic Dermatology, 2020
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025
- [Clinical Evaluation of a Soap-Free Cleansing Lotion Containing Sodium Cocoyl Apple Amino Acids for Effective Impurity Removal and Skin Barrier Preservation in Healthy Adults With Diverse Skin Types](https://pubmed.ncbi.nlm.nih.gov/40978887/) Cetyl alcohol · Cureus, 2025
- [Dermatological Effects of a Beeswax-Pine Resin Mixture on Abdominal Skin: A Proof-of-Concept Study Supporting the Development of an Affordable Investigational Ostomy Pouching System in Low-Income Regions](https://pubmed.ncbi.nlm.nih.gov/42758164/) Beeswax cera alba cera · Journal of Wound, Ostomy, and Continence Nursing, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025

## The brands

- French skincare: [Avène](https://lovi.care/skincare/nl/brands/avene)
- Canadian skincare: [MAC](https://lovi.care/skincare/nl/brands/mac)

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- [CeraVe vs MAC](https://lovi.care/skincare/nl/compare/cerave-vs-mac)
- [La Roche-Posay vs Avène](https://lovi.care/skincare/nl/compare/la-roche-posay-vs-avene)
- [La Roche-Posay vs MAC](https://lovi.care/skincare/nl/compare/la-roche-posay-vs-mac)
- [Dr. Althea vs Avène](https://lovi.care/skincare/nl/compare/dr-althea-vs-avene)
- [Dr. Althea vs MAC](https://lovi.care/skincare/nl/compare/dr-althea-vs-mac)
- [Some By Mi vs Avène](https://lovi.care/skincare/nl/compare/some-by-mi-vs-avene)
- [Some By Mi vs MAC](https://lovi.care/skincare/nl/compare/some-by-mi-vs-mac)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/avene-vs-mac
- United Kingdom: https://lovi.care/skincare/uk/compare/avene-vs-mac
- Ireland: https://lovi.care/skincare/ie/compare/avene-vs-mac
- Germany: https://lovi.care/skincare/de/compare/avene-vs-mac
- France: https://lovi.care/skincare/fr/compare/avene-vs-mac
- Italy: https://lovi.care/skincare/it/compare/avene-vs-mac
- Netherlands: https://lovi.care/skincare/nl/compare/avene-vs-mac (this page)
- Spain: https://lovi.care/skincare/es/compare/avene-vs-mac
- Canada: https://lovi.care/skincare/ca/compare/avene-vs-mac
- Australia: https://lovi.care/skincare/au/compare/avene-vs-mac
- Singapore: https://lovi.care/skincare/sg/compare/avene-vs-mac
- Saudi Arabia: https://lovi.care/skincare/sa/compare/avene-vs-mac
- United Arab Emirates: https://lovi.care/skincare/ae/compare/avene-vs-mac