# Mesoestetic skincare Page: https://lovi.care/skincare/nl/brands/mesoestetic The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands. Mesoestetic is a Spanish skincare brand founded in 1984 and owned by Mesoestetic Pharma Group, S.L.. [mesoestetic.com](https://www.mesoestetic.com/about-us) [tracxn.com](https://tracxn.com/d/companies/mesoestetic/__1eAnF7uALQzHII_So8HqZbHfSUJuilusj9hTisrG0tk) Mesoestetic is beloved for its targeted [serums](https://lovi.care/skincare/nl/ingredients/serum) and meticulously crafted formulas that elevate daily routines. Its products suit mature, sensitive, and uneven skin best, owing to their gentle yet rigorous composition. For acne-prone skin, the standout solution is the Cosmelan 2, which addresses stubborn blemishes with remarkable precision. Every application delivers balanced nourishment to support long-term skin health. This page covers some of the most popular Mesoestetic products; for the whole Mesoestetic range, with a fit score for every product, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=brand&af_sub3=selection_note&af_sub4=pg2ef4ff0360). ### Mesoestetic [serums](https://lovi.care/skincare/nl/ingredients/serum) and treatments #### Serums and treatments - [Cosmelan 2](https://lovi.care/skincare/nl/p/mesoestetic/cosmelan-2/for/acne-prone-skin) — Average fit ## Questions and answers ### Is Mesoestetic worth it? Mesoestetic is worth it because Lovi rates the brand-focused routines Superior for dry, oily, sensitive, combination, and acne-prone skin. Every product from the Mesoestetic products on this page lists no fragrance in its ingredients. ### What are Mesoestetic's best products? Mesoestetic does not have a single best product listed on this page, as Cosmelan 2 rates Average for oily, dry, combination, and mature skin. Lovi rates the Mesoestetic-focused routine Superior for dry, oily, sensitive, combination, and acne-prone skin. ### Does Mesoestetic cause breakouts? Cosmelan 2 rates Average for acne-prone skin, meaning it is unlikely to cause breakouts for most shoppers. Lovi rates the Mesoestetic-focused routine Superior for acne-prone skin. ### Is Mesoestetic fragrance-free? Yes, every product from Mesoestetic on this page lists no fragrance in its ingredients. ### What are the key ingredients in Mesoestetic products? Mesoestetic products on this page are formulated without any added fragrance. They feature key ingredients such as [niacinamide](https://lovi.care/skincare/nl/ingredients/niacinamide), [kojic acid](https://lovi.care/skincare/nl/ingredients/kojic-acid), and [azelaic acid](https://lovi.care/skincare/nl/ingredients/azelaic-acid) that help address skin concerns like dark spots and acne. [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) ### How do I build a Mesoestetic skincare routine? To build a Mesoestetic skincare routine, Lovi rates a Mesoestetic-focused routine Superior for dry, oily, sensitive, combination, and acne-prone skin. Every product from the Mesoestetic products on this page lists no fragrance in its ingredients. ### What are good alternatives to Mesoestetic? Good alternatives to Mesoestetic include ISDIN, Sesderma, Heliocare, Theramid, Endocare, and ISDIN Isdinceutics, which also have brand pages on Lovi. ### Mesoestetic vs ISDIN: which is better? Mesoestetic and ISDIN are both strong choices, as Lovi rates the Mesoestetic-focused routine Superior for dry, oily, sensitive, combination, and acne-prone skin, while the ISDIN-focused routine is also rated Superior across those same skin types. ### Who owns Mesoestetic, and where is it from? Mesoestetic is a Spanish brand founded in 1984, owned by Mesoestetic Pharma Group, S.L.. [mesoestetic.com](https://www.mesoestetic.com/about-us) [tracxn.com](https://tracxn.com/d/companies/mesoestetic/__1eAnF7uALQzHII_So8HqZbHfSUJuilusj9hTisrG0tk) ### Is Mesoestetic cruelty-free? PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list Mesoestetic as cruelty-free. ## Research behind Mesoestetic's key ingredients - [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002 - [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018 - [Tailoring of Retinyl Palmitate-Based Ethosomal Hydrogel as a Novel Nanoplatform for Acne Vulgaris Management: Fabrication, Optimization, and Clinical Evaluation Employing a Split-Face Comparative Study](https://pubmed.ncbi.nlm.nih.gov/34211271/) Retinyl palmitate · International Journal of Nanomedicine, 2021 - [Efficacy and Safety of Azelaic Acid Nanocrystal-Loaded In Situ Hydrogel in the Treatment of Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/33923739/) Azelaic acid · Pharmaceutics, 2021 - [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017 - [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020 - [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024 - [Effects of 15% Azelaic Acid Gel in the Management of Post-Inflammatory Erythema and Post-Inflammatory Hyperpigmentation in Acne Vulgaris](https://pubmed.ncbi.nlm.nih.gov/38734843/) Azelaic acid · Dermatology and Therapy, 2024 - [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023 ## Similar brands - Spanish skincare: [ISDIN](https://lovi.care/skincare/nl/brands/isdin) - Spanish skincare: [Sesderma](https://lovi.care/skincare/nl/brands/sesderma) - Spanish skincare: [Heliocare](https://lovi.care/skincare/nl/brands/heliocare) - Spanish skincare: [Theramid](https://lovi.care/skincare/nl/brands/theramid) - Spanish skincare: [Endocare](https://lovi.care/skincare/nl/brands/endocare) - Spanish skincare: [ISDIN Isdinceutics](https://lovi.care/skincare/nl/brands/isdin-isdinceutics) - Spanish skincare: [Natura Bissé](https://lovi.care/skincare/nl/brands/natura-bisse) - Spanish skincare: [Noche Y Dia](https://lovi.care/skincare/nl/brands/noche-y-dia) ## Compare Mesoestetic - [SKIN1004 vs Mesoestetic](https://lovi.care/skincare/nl/compare/skin1004-vs-mesoestetic) - [Anua vs Mesoestetic](https://lovi.care/skincare/nl/compare/anua-vs-mesoestetic) - [Medicube vs Mesoestetic](https://lovi.care/skincare/nl/compare/medicube-vs-mesoestetic) - [The Ordinary vs Mesoestetic](https://lovi.care/skincare/nl/compare/the-ordinary-vs-mesoestetic) - [Beauty of Joseon vs Mesoestetic](https://lovi.care/skincare/nl/compare/beauty-of-joseon-vs-mesoestetic) - [COSRX vs Mesoestetic](https://lovi.care/skincare/nl/compare/cosrx-vs-mesoestetic) - [CeraVe vs Mesoestetic](https://lovi.care/skincare/nl/compare/cerave-vs-mesoestetic) - [La Roche-Posay vs Mesoestetic](https://lovi.care/skincare/nl/compare/la-roche-posay-vs-mesoestetic) - [Dr. Althea vs Mesoestetic](https://lovi.care/skincare/nl/compare/dr-althea-vs-mesoestetic) - [Some By Mi vs Mesoestetic](https://lovi.care/skincare/nl/compare/some-by-mi-vs-mesoestetic) - [Torriden vs Mesoestetic](https://lovi.care/skincare/nl/compare/torriden-vs-mesoestetic) - [celimax vs Mesoestetic](https://lovi.care/skincare/nl/compare/celimax-vs-mesoestetic) - [Purito vs Mesoestetic](https://lovi.care/skincare/nl/compare/purito-vs-mesoestetic) - [Cetaphil vs Mesoestetic](https://lovi.care/skincare/nl/compare/cetaphil-vs-mesoestetic) - [Paula's Choice vs Mesoestetic](https://lovi.care/skincare/nl/compare/paula-s-choice-vs-mesoestetic) - [Neutrogena vs Mesoestetic](https://lovi.care/skincare/nl/compare/neutrogena-vs-mesoestetic) - [Kiehl's vs Mesoestetic](https://lovi.care/skincare/nl/compare/kiehl-s-vs-mesoestetic) - [Caudalie vs Mesoestetic](https://lovi.care/skincare/nl/compare/caudalie-vs-mesoestetic) - [Dermalogica vs Mesoestetic](https://lovi.care/skincare/nl/compare/dermalogica-vs-mesoestetic) - [Good Molecules vs Mesoestetic](https://lovi.care/skincare/nl/compare/good-molecules-vs-mesoestetic) ## Popular brands - Korean skincare: [SKIN1004](https://lovi.care/skincare/nl/brands/skin1004) - Korean skincare: [Anua](https://lovi.care/skincare/nl/brands/anua) - Korean skincare: [Medicube](https://lovi.care/skincare/nl/brands/medicube) - Canadian skincare: [The Ordinary](https://lovi.care/skincare/nl/brands/the-ordinary) - Korean skincare: [Beauty of Joseon](https://lovi.care/skincare/nl/brands/beauty-of-joseon) - Korean skincare: [COSRX](https://lovi.care/skincare/nl/brands/cosrx) - American skincare: [CeraVe](https://lovi.care/skincare/nl/brands/cerave) - French skincare: [La Roche-Posay](https://lovi.care/skincare/nl/brands/la-roche-posay) - Korean skincare: [Dr. Althea](https://lovi.care/skincare/nl/brands/dr-althea) - Korean skincare: [Some By Mi](https://lovi.care/skincare/nl/brands/some-by-mi) - Korean skincare: [Torriden](https://lovi.care/skincare/nl/brands/torriden) - Korean skincare: [celimax](https://lovi.care/skincare/nl/brands/celimax) - Korean skincare: [Purito](https://lovi.care/skincare/nl/brands/purito) - Korean skincare: [ROUND LAB](https://lovi.care/skincare/nl/brands/round-lab) - American skincare: [Cetaphil](https://lovi.care/skincare/nl/brands/cetaphil) - American skincare: [Paula's Choice](https://lovi.care/skincare/nl/brands/paula-s-choice) - American skincare: [Neutrogena](https://lovi.care/skincare/nl/brands/neutrogena) - Korean skincare: [AXIS-Y](https://lovi.care/skincare/nl/brands/axis-y) - American skincare: [Kiehl's](https://lovi.care/skincare/nl/brands/kiehl-s) - Korean skincare: [d'Alba](https://lovi.care/skincare/nl/brands/d-alba) ## About the Lovi Fit Lovi: Unbiased, science-based skincare AI trained on real user outcomes. Lovi rates every product from its full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning. Behind these ratings: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board). Page built Nov 8, 2026. More from Lovi: https://lovi.care/skincare/llms.txt ## This page in other countries - United States: https://lovi.care/skincare/brands/mesoestetic - United Kingdom: https://lovi.care/skincare/uk/brands/mesoestetic - Ireland: https://lovi.care/skincare/ie/brands/mesoestetic - Germany: https://lovi.care/skincare/de/brands/mesoestetic - France: https://lovi.care/skincare/fr/brands/mesoestetic - Italy: https://lovi.care/skincare/it/brands/mesoestetic - Netherlands: https://lovi.care/skincare/nl/brands/mesoestetic (this page) - Spain: https://lovi.care/skincare/es/brands/mesoestetic - Canada: https://lovi.care/skincare/ca/brands/mesoestetic - Australia: https://lovi.care/skincare/au/brands/mesoestetic - Singapore: https://lovi.care/skincare/sg/brands/mesoestetic - Saudi Arabia: https://lovi.care/skincare/sa/brands/mesoestetic - United Arab Emirates: https://lovi.care/skincare/ae/brands/mesoestetic