# Differin skincare

Page: https://lovi.care/skincare/nl/brands/differin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the Netherlands.

Differin is a French skincare brand founded in 1995 and owned by Galderma Group AG.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Galderma) [galderma.com](https://www.galderma.com/glance) [beautymatter.com](https://beautymatter.com/articles/how-differin-is-gaming-its-way-into-teen-skincare-routines)

Differin is deeply loved for its thoughtful formulations, including targeted [serums](https://lovi.care/skincare/nl/ingredients/serum) and clarifying cleansers. Its products suit oily, acne-prone, and maturing skin best because of these specialized formulas. For acne-prone skin, the standout choice is the Dark Spot Correcting Serum; for skin with dark spots, it is the Daily Deep Cleanser; and for mature skin, it is the Gel. Together, these thoughtful offerings provide a calm, steady foundation for everyday skin health.

This page covers some of the most popular Differin products; for the whole Differin range, with a fit score for every product, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=brand&af_sub3=selection_note&af_sub4=pgd1a92bea35).

### Other Differin products

#### Other products

- [Gel](https://lovi.care/skincare/nl/p/differin/gel/for/oily-acne-prone-skin) — High fit
- [Dark Spot Correcting Serum](https://lovi.care/skincare/nl/p/differin/dark-spot-correcting-serum/for/sensitive-skin) — High fit
- [Daily Deep Cleanser](https://lovi.care/skincare/nl/p/differin/daily-deep-cleanser/for/oily-acne-prone-skin) — Average fit

## People Say

★4.5

Overall rating based on 66.6k+ reviews

Reviewers most often praise Differin for clearing breakouts, fading hyperpigmentation, and being gentle on skin. The most common complaints are initial dryness and slow results.

Sources: lovi.care, amazon.com, walmart.com, target.com, ulta.com, drugs.com, and more

## Questions and answers

### Is Differin worth it?

Differin is worth it because Lovi rates the brand-focused routines Superior for dry, oily, sensitive, combination, and acne-prone skin. The Differin products on this page list no fragrance in their ingredients.

### What are Differin's best products?

Differin offers a range of options including Gel, Dark Spot Correcting [Serum](https://lovi.care/skincare/nl/ingredients/serum), and Daily Deep Cleanser. Lovi rates the Differin-focused routine Superior for acne-prone, oily, sensitive, combination, and dry skin.

### Which Differin cleanser is best for oily skin?

Daily Deep Cleanser is the best Differin cleanser for oily skin, as Lovi rates it Average for this skin type.

### Does Differin cause breakouts?

Differin helps clear breakouts by treating clogged pores and reducing blemishes. The Differin products on this page are fragrance-free.

[American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/) [American Journal of Clinical Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34674160/)

### Is Differin fragrance-free?

Yes, every one of the Differin products on this page lists no fragrance in its ingredients. This helps keep skin calm without unwanted scents.

### What are the key ingredients in Differin products?

Differin products feature key ingredients such as [adapalene](https://lovi.care/skincare/nl/ingredients/adapalene), [benzoyl peroxide](https://lovi.care/skincare/nl/ingredients/benzoyl-peroxide), [niacinamide](https://lovi.care/skincare/nl/ingredients/niacinamide), and [glycerin](https://lovi.care/skincare/nl/ingredients/glycerin), which help clear breakouts, fade dark spots, and keep skin soft. The Differin products on this page are also fragrance-free.

[American Journal of Clinical Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29549588/) [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### How do I build a Differin skincare routine?

To build a Differin routine, start by cleansing with Daily Deep Cleanser, then apply Gel or Dark Spot Correcting Serum depending on your skin goals. Lovi rates Differin-focused routines Superior for dry, oily, sensitive, combination, and acne-prone skin.

### What are good alternatives to Differin?

La Roche-Posay is a good alternative, as Lovi rates a La Roche-Posay-focused routine Superior for dry and sensitive skin, and High for oily, combination, and acne-prone skin.

### Differin vs La Roche-Posay: which is better?

Differin rates Superior for dry, oily, sensitive, combination, and acne-prone skin, performing on par with or slightly above La Roche-Posay across those routines. The Differin products on this page are all free of added fragrance.

### Who owns Differin, and where is it from?

Differin is a French brand founded in 1995, owned by Galderma Group AG.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Galderma) [galderma.com](https://www.galderma.com/glance) [beautymatter.com](https://beautymatter.com/articles/how-differin-is-gaming-its-way-into-teen-skincare-routines)

### Is Differin cruelty-free?

PETA, Leaping Bunny, and Cruelty Free International, the registries Lovi checks, do not list Differin as cruelty-free.

## Research behind Differin's key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide · The Cochrane Database of Systematic Reviews, 2020
- [Prevention and Reduction of Atrophic Acne Scars with Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in Subjects with Moderate or Severe Facial Acne: Results of a 6-Month Randomized, Vehicle-Controlled Trial Using Intra-Individual Comparison](https://pubmed.ncbi.nlm.nih.gov/29549588/) Adapalene retinoid, Adapalene · American Journal of Clinical Dermatology, 2018
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide · Journal of Shoulder and Elbow Surgery, 2021
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Adapalene retinoid, Adapalene, Benzoyl peroxide · American Journal of Clinical Dermatology, 2022
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A topical gel of tea tree oil nanoemulsion containing adapalene versus adapalene marketed gel in patients with acne vulgaris: a randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/34251536/) Adapalene retinoid, Adapalene · Archives of Dermatological Research, 2022
- [Semi-Solid Dosage Forms Containing Pranoprofen-Loaded NLC as Topical Therapy for Local Inflammation: In Vitro, Ex Vivo and In Vivo Evaluation](https://pubmed.ncbi.nlm.nih.gov/37367119/) Carbomer 940 · Gels, 2023
- [Clindamycin phosphate 1.2%/adapalene 0.15%/benzoyl peroxide 3.1% gel for moderate-to-severe acne: Efficacy and safety results from two randomized phase 3 trials](https://pubmed.ncbi.nlm.nih.gov/37656094/) Adapalene retinoid · Journal of the American Academy of Dermatology, 2023
- [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide · Journal of the American Academy of Dermatology, 2023
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects](https://pubmed.ncbi.nlm.nih.gov/22142309/) Sodium ascorbyl phosphate · Experimental Dermatology, 2012
- [Hippophae rhamnoides oil-in-water (O/W) emulsion improves barrier function in healthy human subjects](https://pubmed.ncbi.nlm.nih.gov/25362595/) Hippophae rhamnoides oil · Pakistan Journal of Pharmaceutical Sciences, 2014
- [Hydroxyethyl cellulose as carbohydrate polymer scaffold for surfactant-free serums with enhanced hydration and structural stability](https://pubmed.ncbi.nlm.nih.gov/42214523/) Hydroxyethylcellulose · International Journal of Biological Macromolecules, 2026

## Similar brands

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi rates every product from its full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind these ratings: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/brands/differin
- United Kingdom: https://lovi.care/skincare/uk/brands/differin
- Ireland: https://lovi.care/skincare/ie/brands/differin
- Germany: https://lovi.care/skincare/de/brands/differin
- France: https://lovi.care/skincare/fr/brands/differin
- Italy: https://lovi.care/skincare/it/brands/differin
- Netherlands: https://lovi.care/skincare/nl/brands/differin (this page)
- Spain: https://lovi.care/skincare/es/brands/differin
- Canada: https://lovi.care/skincare/ca/brands/differin
- Australia: https://lovi.care/skincare/au/brands/differin
- Singapore: https://lovi.care/skincare/sg/brands/differin
- Saudi Arabia: https://lovi.care/skincare/sa/brands/differin
- United Arab Emirates: https://lovi.care/skincare/ae/brands/differin
