Timeless Coenzyme Q10 Serum for oily acne-prone skin
Ubiquinone
Matrixyl 3000
Sodium Hyaluronate
Aloe Barbadensis
Vitamin EHigh
- HighOily Skin Fit
- HighEffectiveness
- HighSafety
A great choice for oily acne-prone skin; a few serums fit it even better.
This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.
Page built Nov 8, 2026How the Fit score works
Lovi Assistant explains
- Offers excellent anti-aging benefits for your oily skin, as Matrixyl 3000 and Ubiquinone work to firm and smooth texture while Glycerin and Sodium Hyaluronate hydrate without adding excess oil.
- The serum provides moderate support for your acne, blemishes, and breakouts, with Ubiquinone and Vitamin E offering antioxidant and anti-inflammatory properties.
- The safety profile is excellent, with Aloe Barbadensis and the absence of harsh ingredients ensuring no irritation for your oily skin.
How to apply
- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
People Say
★4.8Overall rating based on 6.0k+ reviewsBased on a very large amount of data, this serum is highly praised for its lightweight, fast-absorbing, and non-greasy formula that effectively hydrates and smooths skin texture, particularly favored by those with mature, combination, or sensitive skin. Users frequently report improvements in skin texture and hydration, leading to a firmer, more youthful appearance without irritation. Some users noted limited dramatic results or concerns about the product size and potential dryness.
Highlights
Lightweight, fast-absorbing Mostly Mentioned
- “Light feel, not oily or greasy.”
- “Feels lightweight, absorbed quickly.”
- “Absorbs completely without sticky residue.”
Effective hydration Often Mentioned
- “My skin feels 'plumper' and more hydrated.”
- “Leaves my skin feeling and looking... more hydrated.”
- “Keeping my skin soft and moisturized.”
Gentle, non-irritating Often Mentioned
- “I didn't experience any irritation or breakouts.”
- “Gentle and irritation-free, sensitive-skin friendly.”
- “Incredibly gentle and high quality.”
Improves skin texture Often Mentioned
- “My skin looked good and smooth.”
- “Makes a fantastic difference in how my skin looks and feels.”
- “Improving the texture and firmness of your face.”
Limited visible results Sometimes Noted
- “I didn't see a change in my skin.”
- “Others did not observe significant changes despite prolonged use.”
- “I've seen some results, but nothing dramatic.”
Potential dryness Rarely Noted
- “Leaves a little bit of dryness like almost any other serum.”
- “Concerned about the benzylalcohol drying out my skin.”
Small bottle size Rarely Noted
- “The product's small size (30ml) is a common point of criticism.”
- “I wish it came in a larger size.”
Sources: lovi.care, amazon.com, walmart.com, timelessha.com, influenster.com, dermapproved.com, and more
Questions and answers
What makes Timeless Coenzyme Q10 Serum a great fit for oily acne-prone skin?
Timeless Coenzyme Q10 Serum is a great fit because it firms and smooths texture and hydrates your skin without adding excess oil, while also providing moderate support for acne and breakouts. Its gentle formula is unlikely to cause irritation.
Clinical, Cosmetic and Investigational Dermatology, 2017Journal of Cosmetic Dermatology, 2015
Which ingredients make this serum a good fit for oily acne-prone skin?
Matrixyl 3000 and Ubiquinone firm and smooth your skin while Glycerin and Sodium Hyaluronate hydrate it without adding excess oil. Additionally, Ubiquinone and Vitamin E provide antioxidant and anti-inflammatory properties that help support your acne and breakouts.
Clinical, Cosmetic and Investigational Dermatology, 2017Journal of Cosmetic Dermatology, 2015
What does Coenzyme Q10 do for oily acne-prone skin?
Coenzyme Q10 helps energize skin cells and provides antioxidant protection to reduce daily stress on oily, acne-prone skin. It is unlikely to clog pores and may improve the overall health and appearance of aging skin.
What does Matrixyl 3000 do for oily acne-prone skin?
Matrixyl 3000 helps smooth fine lines and supports collagen levels, but because it is typically formulated in rich moisturizers, it may feel too heavy for oily acne-prone skin. Oily acne-prone skin needs lightweight, oil-free hydrators with ingredients like niacinamide or hyaluronic acid that keep skin soft without clogging pores.
Where does this serum go in a skincare routine for oily acne-prone skin?
This serum goes in the evening routine after cleansing and before moisturizing, which keeps things simple and safe. It is gentle on oily skin and helps smooth texture without adding excess oil.
Can I use this serum with retinol, and in what order?
You can use this serum with retinol by applying it during your evening routine after cleansing and toning, followed by your moisturizer. Because this product is gentle and hydrating, it is unlikely to cause irritation when layered with retinol.
How often should I use this serum?
This serum fits your oily acne-prone skin well and is best used in the evening routine. It hydrates and smooths texture without adding excess oil, while antioxidants help calm breakouts.
Clinical, Cosmetic and Investigational Dermatology, 2017Journal of Cosmetic Dermatology, 2015
Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?
This serum is a great fit for oily acne-prone skin and is unlikely to clog pores, cause breakouts, or lead to purging. Its ingredients hydrate without adding excess oil, and it has an excellent safety profile that ensures no irritation.
Clinical, Cosmetic and Investigational Dermatology, 2017BioFactors, 2008
Is this serum fragrance-free and alcohol-free?
It has no drying alcohol and contains fragrance (benzyl alcohol).
What the research says
A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.
Clinical, Cosmetic and Investigational Dermatology, 2017A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo.
Journal of Cosmetic Dermatology, 2015Topical application of CoQ10 improves mitochondrial function in aging skin in vivo, combating cellular signs of aging caused by an age-dependent shift to a functionally anaerobic energy metabolism.
BioFactors, 2008Topical treatment with coenzyme Q10 formulas replenishes Q10 levels in the skin surface and deeper epidermis, augments cellular energy metabolism, and reduces free radicals while increasing antioxidant capacity in stressed skin.
BioFactors, 2015A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.
Clinical Pharmacology, 2018Encapsulating coenzyme Q10 in lipid nanoparticles for topical use improves skin compatibility, protects against degradation, increases skin penetration, and provides controlled release to counteract aging effects.
Colloids and Surfaces. B, Biointerfaces, 2023Review of topical administration of carotenoids and coenzyme Q10 loaded in lipid nanoparticles highlights their improved bioavailability, chemical stability, skin absorption, and photoprotective effects.
Antioxidants, 2021Topical application of CoQ10-formulated products reduces the depth of cutaneous wrinkles and replenishes skin antioxidant levels by stimulating cutaneous energy metabolism and providing antioxidant effects in aging and stressed skin.
The Journal of Clinical and Aesthetic Dermatology, 2024Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants.
Journal of Cosmetic Dermatology, 2026Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.
Journal of Drugs in Dermatology, 2011Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.
Clinical Oral Investigations, 2022Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.
BMC Oral Health, 2019Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief.
Plastic and Reconstructive Surgery, 2018Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo.
Journal of Alternative and Complementary Medicine, 2010Formulations containing 0.10%, 0.25%, and 0.50% freeze-dried Aloe vera extract increased stratum corneum water content compared with the vehicle in 20 female subjects, while transepidermal water loss was not modified.
Skin Research and Technology, 2006Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls.
Journal of Cosmetic Dermatology, 2025Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.
Contemporary Clinical Trials Communications, 2021Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin.
Journal of Cosmetic Dermatology, 2024
Ingredients
Water, Matrixyl 3000, Ubiquinone, Aloe Barbadensis, Glycerin, Sodium Hyaluronate, Vitamin E, Benzyl Alcohol, Dehydroacetic Acid
Behind this fit score
Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.
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Co-founder, Medical Director
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PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex
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Dr. Sofía Perea Pérez, MD, MSc
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Specialist dermatologist, MBBS, MD, IFAAD
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Dermatology MD
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Elina Nazarenko, MD
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Victoria Derkova, MS
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Cosmetic chemist, cosmetic development technologist
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