# Theramid Copper Peptide for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/it/p/theramid/copper-peptide/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [Theramid](https://lovi.care/skincare/it/brands/theramid)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate hydration and anti-aging benefits for your dry and sensitive skin, as glycerin and sodium hyaluronate provide humectant action and barrier repair, while copper tripeptide-1 and acetyl hexapeptide-1 work to minimize fine lines and wrinkles.
- The formula is safe for your dry and sensitive skin, as it lacks harsh ingredients that could cause irritation.
- While the product offers general skincare benefits, its primary focus on hydration and anti-aging may not fully address your specific concerns of dryness and flakiness.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/theramid/copper-peptide/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/it/p/theramid/copper-peptide/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/it/p/theramid/copper-peptide/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/it/p/theramid/copper-peptide/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/it/p/theramid/copper-peptide/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/theramid/copper-peptide/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/theramid/copper-peptide/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/theramid/copper-peptide/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/theramid/copper-peptide/for/oily-acne-prone-skin): High

## Key ingredients

Copper Tripeptide-1, Acetyl Tetrapeptide-2, Sodium Hyaluronate, Bifida Lysate Ferment, Acetyl Glutamine

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))
- Treatment of immortalized human keratinocytes with Acetyl Tetrapeptide-2 increased cell stiffness across its concentration range, while Acetyl Hexapeptide-50 increased stiffness at 0.05 µg/ml but decreased it at 0.5 and 5 µg/ml compared to untreated controls. ([International Journal of Peptide Research and Therapeutics, 2018](https://pubmed.ncbi.nlm.nih.gov/30416406/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))

## Why other serums fit dry sensitive skin better

- Tocopherol succinate-loaded ethosomal gel increased skin deposition, stability, moisture, and mechanical properties in 13 human subjects compared to a control gel over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35274433/))
- In 50 participants with sensitive skin, a Ceramide NP C15-containing emollient improved skin barrier function with a significant reduction in transepidermal water loss and induced modest changes in skin microbiota compared to the vehicle. ([Skin Pharmacology and Physiology, 2026](https://pubmed.ncbi.nlm.nih.gov/41758783/))
- Hydrogels containing vitamin E-loaded nanostructured lipid carriers exhibited better occlusive properties and long-lasting effects, while vitamin E-loaded nanoemulsions performed a faster skin hydration effect and were selected as more attractive for skin application. ([Colloids and Surfaces. B, Biointerfaces, 2019](https://pubmed.ncbi.nlm.nih.gov/30974262/))

## What reviewers say

A lightweight, fast-absorbing texture is frequently praised, and a moderate number of users report a boost in skin radiance. Some users find the high silicone content problematic for layering and note that copper peptides require careful routine planning to avoid conflicts with other active ingredients.

- Liked: Improves firmness (often mentioned)
- Liked: Lightweight, fast-absorbing (often mentioned)
- Liked: Boosts radiance (sometimes noted)
- Liked: Gentle, non-irritating (sometimes noted)
- Disliked: Hard to combine (sometimes noted)
- Disliked: High silicone content (rarely noted)
- Disliked: No visible results (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Theramid Copper Peptide treatment work for dry sensitive skin?

Theramid Copper Peptide treatment works moderately well for dry sensitive skin by offering gentle hydration and anti-aging benefits, though it may not fully address severe dryness and flakiness. Treatments that fit this skin best need rich moisturizing ingredients for deep moisture retention, skin barrier support, ceramides, and vitamins to soothe and protect without irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this treatment a good fit for dry sensitive skin?

Glycerin and sodium hyaluronate make this treatment a good fit by helping to draw in moisture and soothe dry skin. This product needs ingredients like ceramides, richer moisturizers, and barrier-protecting components to deeply nourish dry skin, relieve flakiness, and prevent moisture loss.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Copper Tripeptide-1 do for dry sensitive skin?

Copper Tripeptide-1 helps calm irritation and protects dry sensitive skin from sun damage while smoothing out wrinkles and supporting a stronger skin barrier. This ingredient may also improve overall firmness and elasticity, though a product for this skin type also needs gentle, soothing hydrators like colloidal oatmeal or plant oils to keep the skin soft and comfortable.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/), [Journal of Biomaterials Science. Polymer Edition, 2008](https://pubmed.ncbi.nlm.nih.gov/18644225/)

### What does Acetyl Tetrapeptide-2 do for dry sensitive skin?

Acetyl Tetrapeptide-2 helps firm and support skin structure, which may improve how resilient dry sensitive skin feels. This ingredient works by helping cells maintain better integrity, though very sensitive skin should introduce it slowly to watch for any irritation.
Sources: [International Journal of Peptide Research and Therapeutics, 2018](https://pubmed.ncbi.nlm.nih.gov/30416406/)

### Where does this treatment go in a skincare routine for dry sensitive skin?

This treatment goes in the evening routine after your soothing toner and before your moisturizer. Dry and sensitive skin of this type needs a richer product focused heavily on deep hydration and soothing ingredients to properly combat dryness and flakiness.

### Can I use this treatment with retinol, and in what order?

You can use this treatment with retinol by applying the treatment first and following with your retinol at night. Because this product lacks harsh ingredients, it is unlikely to irritate your skin, but dry and sensitive skin needs products that also bring extra moisture and soothing ingredients to fully tackle dryness and flakiness.

### How often should I use this treatment?

You can use this treatment in your evening routine, applying it after your cleanser and soothing toner and before your moisturizer. A product of this type needs richer hydrators and barrier-repairing ingredients to fully comfort dry and sensitive skin.

### Can this treatment clog pores, cause breakouts or purging for dry sensitive skin?

This treatment is unlikely to clog pores or cause breakouts on dry sensitive skin, as it is safe and lacks harsh ingredients that could cause irritation. A product of this type needs rich moisturizing ingredients and barrier-supporting agents to properly soothe dryness and flakiness.

### Is this treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/dry-sensitive-skin) — Superior fit — €129.99 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-sensitive-skin) — Superior fit — €57.00 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/it/p/augustinus-bader/the-serum/for/dry-sensitive-skin) — Superior fit — €380.10 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/it/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — €9.19 at Amazon
- Soothing Toner: [Pixi Milky Tonic](https://lovi.care/skincare/it/p/pixi/milky-tonic/for/dry-sensitive-skin) — Superior fit — €30.10 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/it/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — €20.40 at Amazon

## Where to buy

No store in Italy has a checked price for this product, so the page shows none.

## Ingredients

Water, Propanediol, Cyclopentasiloxane, Dimethicone, Betaine, Copper Tripeptide-1, Bifida Lysate Ferment, Cyclohexasiloxane, Glycerin, Sodium Chloride, Polyglyceryl-4 Isostearate, Sodium Hyaluronate, Acetyl Tetrapeptide-2, Trifluoroacetyl Tripeptide-2, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-9, Acetyl Hexapeptide-1, Bacillus Folic Acid Extract Ferment Filtrate, Cetyl Peg Ppg-10 1 Dimethicone, Hexyl Laurate, Peg Ppg-18 18 Dimethicone, Lecithin, Acetyl Glutamine, Caprylyl Glycol, Butylene Glycol, Dextran, Disodium Edta, Acetic Acid, Lactic Acid, 1,2-Hexanediol, Sodium Benzoate, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/theramid/copper-peptide/for/dry-sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/theramid/copper-peptide/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/theramid/copper-peptide/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/theramid/copper-peptide/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/theramid/copper-peptide/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/theramid/copper-peptide/for/dry-sensitive-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/theramid/copper-peptide/for/dry-sensitive-skin
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