# The Ordinary Retinol 1% in Squalane for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: Average · Effectiveness: Average · Safety: Low Risk.

Page: https://lovi.care/skincare/it/p/the-ordinary/retinol-1-in-squalane/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [The Ordinary](https://lovi.care/skincare/it/brands/the-ordinary)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other serums fit it better.

## Why this fit

- Offers moderate treatment for wrinkles and fine lines due to the presence of retinol, which works well for your normal skin type by promoting collagen production and reducing the appearance of aging.
- Squalane and jojoba seed oil provide supportive hydration and emollient action, though they do not directly target your primary concern of wrinkles and fine lines.
- The product is generally safe for your normal skin, but the retinol may cause some irritation if your skin is not accustomed to retinoids.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/the-ordinary/retinol-1-in-squalane/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/the-ordinary/retinol-1-in-squalane/for/dry-skin): Caution
- [Combination skin](https://lovi.care/skincare/it/p/the-ordinary/retinol-1-in-squalane/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/it/p/the-ordinary/retinol-1-in-squalane/for/sensitive-skin): Low
- [Acne-prone skin](https://lovi.care/skincare/it/p/the-ordinary/retinol-1-in-squalane/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/it/p/the-ordinary/retinol-1-in-squalane/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/the-ordinary/retinol-1-in-squalane/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/it/p/the-ordinary/retinol-1-in-squalane/for/dry-sensitive-skin): Caution
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/the-ordinary/retinol-1-in-squalane/for/oily-acne-prone-skin): Average

## Key ingredients

Retinol, Squalane, Solanum Lycopersicum Fruit Extract Tomato Fruit Extract, Jojoba Seed Oil, Bht

## What the research says

- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical application of all-trans-retinol induced epidermal thickening and increased retinoid binding protein expression similar to all-trans-retinoic acid in normal human skin, but without causing significant erythema or measurable retinoic acid levels. ([The Journal of Investigative Dermatology, 1995](https://pubmed.ncbi.nlm.nih.gov/7561157/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Topical lycopene-based emulgel significantly enhanced skin hydration and elasticity while reducing erythema, melanin, and sebum contents in human volunteers compared to a placebo formulation over 12 weeks. ([European Journal of Pharmaceutics and Biopharmaceutics, 2022](https://pubmed.ncbi.nlm.nih.gov/36283632/))
- Cosmetic formulations containing lycopene and melatonin showed significant differences in skin sebum content, hydration, elasticity, erythema index, and melanin index compared to control in 36 healthy women. ([Skin Pharmacology and Physiology, 2020](https://pubmed.ncbi.nlm.nih.gov/33070140/))
- Topical delivery of lycopene via MG- and TG-containing microemulsions significantly increased stratum corneum and viable skin layer penetration compared to a control solution, with the MG-containing microemulsion also increasing skin antioxidant activity by 10-fold. ([Journal of Pharmaceutical Sciences, 2010](https://pubmed.ncbi.nlm.nih.gov/19798758/))
- Clay jojoba oil facial masks reduced total skin lesions by a mean of 54% after 6 weeks in 133 participants with acne-prone, lesioned skin and mild acne compared to baseline. ([Forschende Komplementarmedizin, 2012](https://pubmed.ncbi.nlm.nih.gov/22585103/))
- Topical application of jojoba wax reduced LPS-induced secretion of IL-6, IL-8, and TNFα by approximately 30% and increased the synthesis of pro-collagen III and hyaluronic acid compared to untreated skin in an ex-vivo human skin organ culture model. ([Frontiers in Pharmacology, 2024](https://pubmed.ncbi.nlm.nih.gov/38344180/))
- Topical jojoba oil application in male mice decreased exercise-induced pro-inflammatory gene expression (Il-1b and Il-6 in soleus, Il-1b in gastrocnemius) compared to untreated exercised mice. ([Biomolecules, 2025](https://pubmed.ncbi.nlm.nih.gov/41154623/))

## Why other serums fit mature skin better

- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Caviar oil enhanced adipocyte differentiation in vitro, reduced MMP expression while increasing collagen and elastin formation ex vivo, and improved skin moisture, elasticity, and density in 102 participants over four weeks of Cavi Balm usage compared to baseline. ([In Vivo, 2023](https://pubmed.ncbi.nlm.nih.gov/37652485/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))

## What reviewers say

This water-free serum is widely praised by users with dry or mature skin for its ability to deeply hydrate while delivering potent anti-aging benefits, such as reduced fine lines and smoother texture. Its oil-based squalane formula is frequently described as heavy or greasy, making it a polarizing choice for those with oily or acne-prone skin who often struggle with absorption.

- Liked: Highly affordable (mostly mentioned)
- Disliked: Greasy/oily finish (mostly mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Moisturizing base (often mentioned)
- Liked: Effective anti-aging (sometimes noted)
- Disliked: Irritation & sensitivity (sometimes noted)
- Disliked: Short shelf life (rarely noted)
- Disliked: Unpleasant scent (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week, and work up to daily use if your skin likes it.
- Apply this serum after your toner and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- You can apply the serum on dry skin for the best results against fine lines.
- Always do a patch test before your first use and avoid the sensitive eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does The Ordinary Retinol 1% in Squalane work for mature skin?

The Ordinary Retinol 1% in Squalane works moderately well for mature skin, offering helpful treatment for wrinkles and fine lines while squalane and jojoba seed oil provide supportive hydration. The retinol may cause some irritation if your skin is not accustomed to retinoids. A product of this type needs exceptional safety with no risk of irritation, highly effective anti-aging ingredients that target fine lines, and rich antioxidants and peptides for optimal moisture retention and elasticity.

### Which ingredients make this serum a good fit for mature skin?

Retinol makes this serum a good fit for mature skin by helping smooth out wrinkles and fine lines, while squalane and jojoba seed oil provide supportive moisture. However, a product for this skin needs high safety without irritation risk, potent antioxidants, peptides, and moisture-retaining ingredients to improve firmness and elasticity.

### What does Retinol do for mature skin?

Retinol helps smooth out fine lines and wrinkles while improving overall skin thickness and firmness over time. It may also cause temporary dryness, scaling, or stinging as your skin gets used to it.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### What does Squalane do for mature skin?

Squalane helps keep mature skin feeling soft and smooth by boosting moisture and protecting the skin barrier. It also provides antioxidant support that helps improve the look of fine lines and wrinkles over time.
Sources: [Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/), [Journal of Nanoscience and Nanotechnology, 2010](https://pubmed.ncbi.nlm.nih.gov/21137794/)

### Where does this serum go in a skincare routine for mature skin?

This treatment goes in the evening routine after cleansing and before moisturizing, though mature skin also needs products with collagen-boosting ingredients and targeted wrinkle-fighting actives that fit even better.

### Can I use this serum with vitamin C, and in what order?

You can use this treatment alongside vitamin C by applying your vitamin C in the morning and saving this retinol serum for your evening routine. Using retinol at night helps avoid mixing potent actives while still smoothing fine lines, though a product of this type for mature skin also needs rich moisturizers and gentle soothing ingredients to keep dry skin calm and comfortable.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### How often should I use this serum?

This treatment works well for mature skin when used in your evening routine, though you may want to start slowly to help your skin adjust to the retinol. Mature skin of this type needs strong collagen-boosting ingredients and targeted anti-aging actives, along with rich nourishing oils that keep the surface soft and smooth.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### Can this serum clog pores, cause breakouts or purging for mature skin?

This product may cause some irritation or breakouts if your skin is not yet accustomed to retinol. A product for mature skin needs ingredients that smooth fine lines without a greasy finish.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/mature-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/mature-skin) — Superior fit — €129.99 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vita-c-serum/for/mature-skin) — High fit — €34.95 at Amazon

## Pairs well with

- Cleanser: [d'Alba White Truffle Return Oil Cream Cleanser](https://lovi.care/skincare/it/p/d-alba/white-truffle-return-oil-cream-cleanser/for/mature-skin) — Superior fit — €24.99 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/it/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — €16.03 at Amazon
- Moisturizer: [Elizabeth Arden Ceramide Lift and Firm Night Cream](https://lovi.care/skincare/it/p/elizabeth-arden/advanced-ceramide-lift-and-firm-night-cream/for/mature-skin) — Superior fit — €53.50 at Amazon

## Where to buy

- Amazon.it: €10.59 (https://www.amazon.it/dp/B0779YGB2G?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €10.35 (https://www.lookfantastic.it/p/the-ordinary-retinol-serum-1-in-squalane-30ml/11638503/)
Prices checked 17 Oct – 5 Nov 2026.

## Ingredients

Squalane, Caprylic Capric Triglyceride, Retinol, Solanum Lycopersicum Fruit Extract Tomato Fruit Extract, Jojoba Seed Oil, Bht, Hydroxymethoxyphenyl Decanone, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-ordinary/retinol-1-in-squalane/for/mature-skin
- United Kingdom: https://lovi.care/skincare/uk/p/the-ordinary/retinol-1-in-squalane/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/the-ordinary/retinol-1-in-squalane/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/the-ordinary/retinol-1-in-squalane/for/mature-skin
- France: https://lovi.care/skincare/fr/p/the-ordinary/retinol-1-in-squalane/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/the-ordinary/retinol-1-in-squalane/for/mature-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/the-ordinary/retinol-1-in-squalane/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/the-ordinary/retinol-1-in-squalane/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/the-ordinary/retinol-1-in-squalane/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/the-ordinary/retinol-1-in-squalane/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/the-ordinary/retinol-1-in-squalane/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/the-ordinary/retinol-1-in-squalane/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/the-ordinary/retinol-1-in-squalane/for/mature-skin
