# The Ordinary Multi-Peptide + HA Serum for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: Superior · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/it/p/the-ordinary/multi-peptide-ha-serum/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Italy.

Brand: [The Ordinary](https://lovi.care/skincare/it/brands/the-ordinary)
Category: [Serums and treatments](https://lovi.care/skincare/it/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for your normal skin, as the multiple peptides and hyaluronic acid derivatives provide excellent plumping and firming effects, alongside general hydration. Glycerin and Allantoin offer supportive soothing for your redness and irritation, but are not targeted to address these concerns directly.
- The formulation is safe for your sensitive skin due to the absence of harsh ingredients and the inclusion of soothing agents like Allantoin.
- The product is well-suited for normal skin types, providing excellent humectant action and collagen stimulation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/it/p/the-ordinary/multi-peptide-ha-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/it/p/the-ordinary/multi-peptide-ha-serum/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/it/p/the-ordinary/multi-peptide-ha-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/it/p/the-ordinary/multi-peptide-ha-serum/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/it/p/the-ordinary/multi-peptide-ha-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/it/p/the-ordinary/multi-peptide-ha-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/it/p/the-ordinary/multi-peptide-ha-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/it/p/the-ordinary/multi-peptide-ha-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/it/p/the-ordinary/multi-peptide-ha-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Multi-Peptides, Sodium Hyaluronate, Lactococcus Lysate Ferment, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))
- A peptide complex stimulated basement membrane protein expressions and significantly improved skin wrinkles at all five measured sites after two weeks in 22 healthy Asian female volunteers older than 40 years. ([International Journal of Molecular Sciences, 2019](https://pubmed.ncbi.nlm.nih.gov/31861912/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Acetyl hexapeptide-3 and tripeptide-10 citrulline demonstrated antiwrinkle efficacy and decreased transepidermal water loss in twenty-four healthy volunteers compared to control groups, though synergistic effects between the two peptides remained unclear. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28150423/))
- Daily topical acetyl hexapeptide-8 showed a trend toward a longer time until return to baseline Jankovic Blepharospasm Rating Scale scores compared to placebo (3.7 months vs. 3.0 months) in 24 patients with blepharospasm receiving botulinum toxin therapy. ([European Journal of Neurology, 2013](https://pubmed.ncbi.nlm.nih.gov/23146065/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))

## Why other serums fit sensitive skin better

- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))
- In 50 participants with sensitive skin, a Ceramide NP C15-containing emollient improved skin barrier function with a significant reduction in transepidermal water loss and induced modest changes in skin microbiota compared to the vehicle. ([Skin Pharmacology and Physiology, 2026](https://pubmed.ncbi.nlm.nih.gov/41758783/))

## What reviewers say

Based on a very large amount of data, users with dry, mature, or dehydrated skin frequently praise this serum for its ability to plump the skin and smooth texture, often noting a reduction in fine dehydration lines. While many appreciate it as an affordable "all-in-one" anti-aging solution, a minority of users report breakouts or a lack of visible results regarding deeper wrinkles.

- Liked: Deeply hydrates (mostly mentioned)
- Liked: Great value (often mentioned)
- Liked: Smooths texture (often mentioned)
- Liked: Plumps and firms (sometimes noted)
- Liked: Reduces fine lines (sometimes noted)
- Disliked: Conflicts with actives (sometimes noted)
- Disliked: Unclear results (sometimes noted)
- Disliked: Allergic reactions (rarely noted)
- Disliked: Causes breakouts (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does the Multi-Peptide + HA Serum work for sensitive skin?

The Ordinary Multi-Peptide + HA Serum works moderately well for sensitive skin, offering good hydration and firming effects along with soothing ingredients like allantoin that keep it safe from harsh irritation. Treatments that fit sensitive skin better need ingredients like niacinamide or soothing plant extracts to directly calm redness and irritation while maintaining high compatibility.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [International Journal of Molecular Sciences, 2019](https://pubmed.ncbi.nlm.nih.gov/31861912/)

### Which ingredients make this serum a good fit for sensitive skin?

This serum works for sensitive skin because it contains soothing allantoin and lacks harsh ingredients that trigger irritation. To be an even better fit for this skin type, a product of this type needs ingredients like niacinamide and snail secretion filtrate that directly target redness and irritation.

### What do Peptides do for sensitive skin?

Peptides help support and strengthen sensitive skin while improving the look of lines and wrinkles. They are generally safe and well-tolerated by delicate skin types, helping to keep the skin looking smooth and firm.
Sources: [International Journal of Molecular Sciences, 2019](https://pubmed.ncbi.nlm.nih.gov/31861912/)

### What does Hyaluronic Acid do for sensitive skin?

Hyaluronic acid helps calm and hydrate sensitive skin while supporting the skin barrier to keep it soft and comfortable. Clinical studies show it improves surface moisture and reduces dryness, roughness, and redness without irritation.
Sources: [Journal of Drugs in Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41037531/), [Journal of Cosmetic Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/29356277/)

### Where does this serum go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. It is safe for sensitive skin due to soothing ingredients like Allantoin, but for this skin type, a product of this type needs extra calming agents and barrier-strengthening ingredients to provide better overall comfort.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first and letting it absorb before putting on your retinol. This product is generally safe for sensitive skin due to the lack of harsh ingredients, but a product for this skin needs more targeted soothing agents to properly calm redness and irritation.

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. A product for sensitive skin needs soothing ingredients like allantoin and gentle hydrating agents to calm redness and irritation while keeping skin soft.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to cause breakouts for sensitive skin, as reviewer complaints about breakouts are low and the formula lacks harsh pore-clogging ingredients. To better care for sensitive skin, a product of this type needs dedicated soothing agents and calming plant extracts that directly target redness and irritation.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/it/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — €57.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/it/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — €129.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/it/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — €35.10 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/it/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/sensitive-skin) — Superior fit — €17.59 at Amazon
- Soothing Toner: [Pixi Milky Tonic](https://lovi.care/skincare/it/p/pixi/milky-tonic/for/sensitive-skin) — Superior fit — €30.10 at Amazon
- Moisturizer with Sun Protection: [Clinique Mineral Sunscreen Fluid for Face SPF 50](https://lovi.care/skincare/it/p/clinique/broad-spectrum-spf-50-mineral-sunscreen-fluid-for-face/for/sensitive-skin) — Superior fit — €19.21 at Amazon

## Where to buy

- Amazon.it: €17.89 (https://www.amazon.it/dp/B0BLHW7JZM?tag=lovi-care-web-product09-21&linkCode=osi&th=1&psc=1)
- Lookfantastic: €33.24 (https://www.lookfantastic.it/p/the-ordinary-multi-peptide-copper-peptides-1-serum-30ml/14853143/)
Prices checked 15 Oct – 3 Nov 2026.

## Ingredients

Water, Glycerin, Lactococcus Lysate Ferment, Acetyl Hexapeptide-8, Pentapeptide-18, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-38, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Acetylarginyltryptophyl Diphenylglycine, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Allantoin, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Arginine, Aspartic Acid, Trehalose, Fructose, Glucose, Maltose, Urea, Sodium Pca, Pca, Sodium Lactate, Citric Acid, Hydroxypropyl Cyclodextrin, Sodium Chloride, Sodium Hydroxide, Butylene Glycol, Pentylene Glycol, Acacia Senegal Gum, Xanthan Gum, Carbomer, Polysorbate 20, Ppg-26-Buteth-26, Peg-40 Hydrogenated Castor Oil, Trisodium Ethylenediamine Disuccinate, Ethoxydiglycol, Sodium Benzoate, Caprylyl Glycol, Ethylhexylglycerin, Phenoxyethanol, Chlorphenesin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-ordinary/multi-peptide-ha-serum/for/sensitive-skin
- United Kingdom: https://lovi.care/skincare/uk/p/the-ordinary/multi-peptide-ha-serum/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/the-ordinary/multi-peptide-ha-serum/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/the-ordinary/multi-peptide-ha-serum/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/the-ordinary/multi-peptide-ha-serum/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/the-ordinary/multi-peptide-ha-serum/for/sensitive-skin (this page)
- Netherlands: https://lovi.care/skincare/nl/p/the-ordinary/multi-peptide-ha-serum/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/the-ordinary/multi-peptide-ha-serum/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/the-ordinary/multi-peptide-ha-serum/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/the-ordinary/multi-peptide-ha-serum/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/the-ordinary/multi-peptide-ha-serum/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/the-ordinary/multi-peptide-ha-serum/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/the-ordinary/multi-peptide-ha-serum/for/sensitive-skin